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🇲🇽 Leonardo Collado-Torres

@lcolladotor.bsky.social
4.1K followers 2.9K following 455 posts

#RStats @Bioconductor.bsky.social/🧠 genomics @lieberinstitute.bsky.social + Asst. Prof. @jhubiostat.bsky.social/@lcgunam @jtleek.bsky.social @aejaffe.bsky.social alumni/ @libdrstats.bsky.social @CDSBMexico.bsky.social lcolladotor.github.io

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🇲🇽 Leonardo Collado-Torres @lcolladotor.bsky.social · 09/10/2026
140.776 - Statistical Computing at @jhubiostat.bsky.social @johnshopkinssph.bsky.social Lecture 12 summary lcolladotor.github.io/jhustatcompu... #RStats #DataScience #regex #RegularExpression
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🇲🇽 Leonardo Collado-Torres @lcolladotor.bsky.social · 07/10/2026
140.776 - Statistical Computing at @jhubiostat.bsky.social @johnshopkinssph.bsky.social Lecture 11 summary lcolladotor.github.io/jhustatcompu... #RStats #DataScience #lubridate #TimeZones #LeapSeconds
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Nicola Rennie @nrennie.bsky.social · 04/11/2025
I had a great time talking about the process of creating charts with ggplot2 at @rladiesrome.bsky.social tonight! 📊 Slides and code from the session can be found here: nrennie.rbind.io/talks/rladie... #RStats #DataViz #ggplot2 #RLadies
Screenshot of title slide showing title as Developing your data visualisation skills in ggplot2.
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🇲🇽 Leonardo Collado-Torres @lcolladotor.bsky.social · 05/10/2026
140.776 - Statistical Computing at @jhubiostat.bsky.social @johnshopkinssph.bsky.social Lecture 10 summary lcolladotor.github.io/jhustatcompu... #RStats #DataScience
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Dax Kellie @daxkellie.bsky.social · 02/10/2026
This thread is so great! 🤩 To avoid annoying resizing, figured I'd mention an alternative to {ggview}: {showtext} can resize all text to a specific dpi Text is the part that I find I have to fiddle with most when saving #ggplot2 plots, so this usually works for me 😀 #rstats #dataviz
library(showtext)
showtext_opts(dpi = 300)
ggsave(
  plot = my_plot,
  file = "file_name.png",
  width = 6,
  height = 4,
  dpi = 300
)
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🇲🇽 Leonardo Collado-Torres @lcolladotor.bsky.social · 30/09/2026
140.776 - Statistical Computing at @jhubiostat.bsky.social @johnshopkinssph.bsky.social Lecture 09 summary lcolladotor.github.io/jhustatcompu... #RStats #DataScience
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🇲🇽 Leonardo Collado-Torres @lcolladotor.bsky.social · 25/09/2026
140.776 - Statistical Computing at @jhubiostat.bsky.social @johnshopkinssph.bsky.social Lecture 08 summary lcolladotor.github.io/jhustatcompu... #RStats #DataScience
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Kristina Killgrove @killgrove.bsky.social · 22/09/2026
The newly discovered cuneiform tablet fragment contains text from a section of the Treaty of Kadesh related to the treatment of Hittite and Egyptian refugees in the Bronze Age (circa 1269 BC). 🧪🏺
livescience.com
'We have found traces of peace, thousands of years old': Fragment of world's oldest known peace treaty found in Turkey
Archaeologists excavating in the ancient Hittite capital of Hattusha have uncovered a fragment of the world's oldest peace treaty, signed around 1269 B.C.
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🇲🇽 Leonardo Collado-Torres @lcolladotor.bsky.social · 22/09/2026
* Follow @sara-altman.bsky.social and @simonpcouch.com
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🇲🇽 Leonardo Collado-Torres @lcolladotor.bsky.social · 22/09/2026
140.776 - Statistical Computing at @jhubiostat.bsky.social @johnshopkinssph.bsky.social Lecture 07 summary lcolladotor.github.io/jhustatcompu... Guest speaker: @nick-eagles.bsky.social from @lieberinstitute.bsky.social #RStats #DataScience #PositAssistant #AIcoding #Claude
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🇲🇽 Leonardo Collado-Torres @lcolladotor.bsky.social · 18/09/2026
140.776 - Statistical Computing at @jhubiostat.bsky.social @johnshopkinssph.bsky.social Lecture 06 summary lcolladotor.github.io/jhustatcompu... #RStats #DataScience #ggplot2 #DataViz
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Renee García-Flores @freneegf.bsky.social · 16/09/2026
After a few more sprints between rooms and more great talks, we finished the day with the keynote by @christinezhang.bsky.social, Graphics Editor at The NYT. She’s part of the team behind many of the graphs the NYT times used on election night in 2024. (I was fangirling cuz she is so cool 😅)
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Renee García-Flores @freneegf.bsky.social · 16/09/2026
Day 1 of talks at posit::conf(2026) started with keynote speakers @sara-altman.bsky.social and @simonpcouch.com They talked about Posit’s efforts on building AI tools that are correct (trustworthy) while staying convenient (straightforward and intuitive). slides: pos.it/keynote #PositConf2026
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Renee García-Flores @freneegf.bsky.social · 14/09/2026
Woo! posit::conf(2026) started this morning, and I am super happy and grateful to be a Posit Opportunity Scholar this year! I am starting the week attending the Modern R Workflow Workshop taught by @jennybryan.bsky.social and @hadley.nz #PositConf2026
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🇲🇽 Leonardo Collado-Torres @lcolladotor.bsky.social · 15/09/2026
140.776 - Statistical Computing at @jhubiostat.bsky.social @johnshopkinssph.bsky.social Lecture 05 summary lcolladotor.github.io/jhustatcompu... Full notes at gist.github.com/lcolladotor/... #RStats #DataScience #postcards #dplyr #tidyr
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Christine Zhang @christinezhang.bsky.social · 13/09/2026
Headed to Houston for #positconf! I can’t overstate the impact that @posit.co’s opensource products & packages (RStudio, Positron, tidyverse) have had on me as a journalist & data nerd 🤓 Thrilled/terrified to be giving a keynote presentation on Tues. If you’re there, say hello! conf.posit.co/2026/
Keynote Session by Christine Zhang, Graphics Editor at The New York Times: How to Be Clear When You Can’t Be Certain
Sometimes, data visualization is about using charts to illustrate a key point or conclusion gleaned from analyzing the data. But what if you’re not sure what the conclusion is? Presenting examples from news reporting on the topics of elections, polling and economics, I will talk about how I have grappled with uncertainty and how to communicate it to the public.
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🇲🇽 Leonardo Collado-Torres @lcolladotor.bsky.social · 14/09/2026
We are excited to host @areal25.bsky.social at @lieberinstitute.bsky.social In prep, my team did a journal club on the #BigBrain project preprint "Mapping genetic effects on splicing [...]" doi.org/10.1101/2025... from the @trajnp.bsky.social & @davidaknowles.bsky.social labs youtu.be/iVyVcAgPZW8
youtu.be
[2026-09-02] Journal club on "Mapping genetic effects on splicing [...]" aka BigBrain project
YouTube video by Leonardo Collado Torres
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Bernie Mulvey @berniejmulvey.bsky.social · 11/09/2026
Excited to share work with cryostat wizard @heenadivecha.bsky.social looking at gene expression in my favorite brain region (LC) in adult postmortem brain! (Long URL to spare the trouble of identifying cars, buses, beds in 5x5 pixel imgs). (1/x) link.springer.com/epdf/10.1007...
link.springer.com
Molecular programs in human locus coeruleus link APOE and neuromelanin to Alzheimer’s vulnerability
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Jorge Miranda Barrientos @jorge-miranda.bsky.social · 11/09/2026
A little bit of what we are doing in the circuits group at @lieberinstitute.bsky.social. An Amphetamine recruited ensemble in the mPFC tagged with mCherry. Credits to Suhaas Adiraju (Grad student) and @danolivares.bsky.social. #fluorescencefriday
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🇲🇽 Leonardo Collado-Torres @lcolladotor.bsky.social · 08/09/2026
140.776 - Statistical Computing at @jhubiostat.bsky.social @johnshopkinssph.bsky.social Lecture 03 summary lcolladotor.github.io/jhustatcompu... #RStats #DataScience #quarto
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🇲🇽 Leonardo Collado-Torres @lcolladotor.bsky.social · 03/09/2026
140.776 - Statistical Computing at @jhubiostat.bsky.social @johnshopkinssph.bsky.social Lecture 2 summary #RStats #DataScience #git #GitHub #Reproducibility @jennybryan.bsky.social
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🇲🇽 Leonardo Collado-Torres @lcolladotor.bsky.social · 03/09/2026
140.776 - Statistical Computing at @jhubiostat.bsky.social @johnshopkinssph.bsky.social Lecture 1 summary #RStats #DataScience
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Vinny Costa @vincentcostaphd.bsky.social · 28/08/2026
Like I have mentioned before spatial neurobiology is very hard. @svitlanabach.bsky.social makes the impossible seem routine.
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🇲🇽 Leonardo Collado-Torres @lcolladotor.bsky.social · 23/08/2026
Seeing those around me grow and blossom has been very rewarding. I like how they ask me challenging questions which push me to learn more. You also identify your allies who want you to be there, and whom you mutually help grow. ¡Muchísimas gracias 😊! Leo « fixer of everything » #10YearAnniversary
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🇲🇽 Leonardo Collado-Torres @lcolladotor.bsky.social · 23/08/2026
and go through tough weeks with me: that don’t abandon you when it’s convenient. Colleagues that sent the biggest flower arrangement to my mom’s funeral. And some that are taken too young 😔 If you do a job long enough, you become an expert, but can also become a mentor.
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🇲🇽 Leonardo Collado-Torres @lcolladotor.bsky.social · 23/08/2026
what I wanted to learn the past 2 years and how I did so. That drove me to be very productive. Across these challenges, I’ve had the opportunity to work with many great colleagues. Colleagues that set high expectations for me, that push me to grow, that give me direction,
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🇲🇽 Leonardo Collado-Torres @lcolladotor.bsky.social · 23/08/2026
You learn to evaluate if what you don’t like is 5% of the job (even if it can feel like 50%), or whether it truly is 50%. I used to think in 2 year windows and took actions to have many open doors. But also to challenge myself and be ready to say at any interview
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🇲🇽 Leonardo Collado-Torres @lcolladotor.bsky.social · 23/08/2026
I think that’s something natural as you learn that no job is perfect. Mine has given me the flexibility to do other things: like be involved in training Mexicans in my field at my undergrad alma mater #LCG-UNAM & @cdsbmexico.bsky.social, or teaching at my PhD alma mater @jhubiostat.bsky.social.
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🇲🇽 Leonardo Collado-Torres @lcolladotor.bsky.social · 23/08/2026
I had to learn quickly how to lead a team, although my prior experience in Mexico at Winter Genomics helped me: I knew that building a team documentation website would be critical first step. Over these 10 years there have been several types of challenges and I did think about leaving a few times.
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🇲🇽 Leonardo Collado-Torres @lcolladotor.bsky.social · 23/08/2026
Over the next few years Andrew coached me and fought hard to retain me once I got my US permanent residency, which opened the door to new opportunities. Later, I inherited his team when he left for a great new challenge.
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🇲🇽 Leonardo Collado-Torres @lcolladotor.bsky.social · 23/08/2026
The last 3 years of my PhD I worked with LIBD data and was co-advised by @aejaffe.bsky.social. Then on 2016-08-22, #10YearsAgo today, I started my job at @lieberinstitute.bsky.social. The decision to stay on wasn’t the easiest but it felt like the best one for me: one I’m glad that I said yes to.
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Jorge Miranda Barrientos @jorge-miranda.bsky.social · 14/08/2026
Coming back from another amazing GRC frontal cortex. So proud of Suhaas Adiraju who presented some of the work we are doing at @lieberinstitute.bsky.social about Amphetamine ensembles within the mPFC.
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Bioconductor @bioconductor.bsky.social · 13/08/2026
🌟Thank you, R consortium, for supporting the Bioconductor community and helping make BioC2026 possible. R Consortium's mission is to support the R Foundation and organizations that develop, maintain, distribute & use R by identifying, developing & implementing infrastructure projects. #BioC2026
Thank you message for BioC2026 acknowledging R Consortium as a Silver Sponsor, featuring the Bioconductor logo, large colorful "THANK YOU" text, a boxed R Consortium logo with a "SILVER SPONSOR" badge, rainbow-colored raised-arms figures, and the line "Your generosity helped bring our community
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Keri Martinowich @martinowk.bsky.social · 31/07/2026
Congratulations @robinmagnard.bsky.social @daiannaglez.bsky.social and everyone involved from @kr-maynard.bsky.social @triciajanak.bsky.social @lcolladotor.bsky.social teams! Excited to see you all get this paper published and excited for the next steps and follow up studies!
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Jorge Miranda Barrientos @jorge-miranda.bsky.social · 30/07/2026
I am so thrilled to share that i was selected to received the 2026 BBRF young investigator grant from the @bbrfoundation.bsky.social. This is meaningful for me. Thanks so much to @martinowk.bsky.social and the @lieberinstitute.bsky.social for all the support.
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Robin Magnard @robinmagnard.bsky.social · 30/07/2026
The dataset is openly shared and available for download here 👇 github.com/LieberInstit...
github.com
GitHub - LieberInstitute/fentanyl_rat_hb_amy
Contribute to LieberInstitute/fentanyl_rat_hb_amy development by creating an account on GitHub.
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Robin Magnard @robinmagnard.bsky.social · 30/07/2026
It was great working with @daiannaglez.bsky.social on this study! This is the first paper from a collaboration between @triciajanak.bsky.social, @lcolladotor.bsky.social and @kr-maynard.bsky.social labs! Stay tuned for our single-cell profiling follow-up in both males and females!
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Robin Magnard @robinmagnard.bsky.social · 30/07/2026
Integration with existing rodent and human single-cell datasets linked these changes to specific neuronal, glial and vascular cell types. In the amygdala, upregulated genes overlapped with schizophrenia risk genes, while downregulated genes were enriched for substance use disorder risk genes.
The left and middle heatmaps link amygdala differentially expressed gene groups to enriched cell types in mouse and human single-cell datasets. The right heatmap compares habenula and amygdala gene groups with genes associated with disorders in large human genetic studies, known as genome-wide association studies (GWAS). Upregulated amygdala genes overlapped with schizophrenia-associated genes, while downregulated genes overlapped with substance-use-disorder-associated genes.
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Robin Magnard @robinmagnard.bsky.social · 30/07/2026
Bulk RNA-seq found 453 differentially expressed genes in the habenula and 3,041 in the amygdala. Upregulated genes: synaptic transmission and ion conductance in the habenula; metabolic and vesicular functions in the amygdala. Downregulated genes: extracellular matrix functions in both regions.
The upper heatmap shows log-fold changes for genes uniquely or jointly differentially expressed in the habenula and amygdala, separated into upregulated and downregulated groups. The lower matrix links these gene groups to enriched Gene Ontology terms in biological-process, cellular-component, and molecular-function categories. Shared downregulated genes are prominently associated with extracellular-matrix and glial functions.
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Robin Magnard @robinmagnard.bsky.social · 30/07/2026
🧠🧬 What are the effects of intravenous fentanyl self-administration on the habenula and amygdala transcriptomes? In our new Addiction Biology paper, we addressed this question using a chronic long-access model in rats! Here are some highlights 🧵👇 Paper 👉 dx.doi.org/10.1111/adb....
dx.doi.org
Transcriptional Response to Chronic Long‐Access Fentanyl Self‐Administration in Rat Habenula and Amygdala
Chronic intravenous long-access fentanyl self-administration in rats produced transcriptional remodeling in the habenula and amygdala. Bulk RNA-sequencing identified 453 habenula and 3,041 amygdala d...
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Keri Martinowich @martinowk.bsky.social · 16/07/2026
Was HOT 🌞 yesterday for long standing @lieberinstitute.bsky.social annual 🦀 feast tradition. Thanks to everyone on our teams who came out to celebrate another year of accomplishments, community and great science!
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Prashanthi Ravichandran @prashanthi-ravi.bsky.social · 02/07/2026
(1/10) We’re excited to share our recently published study www.sciencedirect.com/science/arti... which uncovers the spatiomolecular landscape of the human NAc, a key reward structure by integrating snRNA-seq with Visium spatial transcriptomics. 🧠 #NAcLIBD #snRNAseq #10xVisium
sciencedirect.com
Spatiomolecular mapping reveals anatomical organization of heterogeneous cell types in the human nucleus accumbens
The nucleus accumbens (NAc) is a key component of the mesolimbic dopamine system that is implicated in several neuropsychiatric disorders. The NAc con…
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Kristen Maynard @kr-maynard.bsky.social · 02/07/2026
Excited to share our new study characterizing spatial gene expression in the human NAc led by @prashanthi-ravi.bsky.social @svitlanabach.bsky.social @rphillips3.bsky.social in collaboration with @martinowk.bsky.social @stephaniehicks.bsky.social @alexisbattle.bsky.social @lcolladotor.bsky.social.
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🇲🇽 Leonardo Collado-Torres @lcolladotor.bsky.social · 29/06/2026
Me pregunto si conocen a alguien en #Guatemala 🇬🇹 que trabaje con datos de transcriptómica ( #scRNAseq #RNAseq #SpatialTranscriptomics) y/o use R y en especial #Bioconductor. Para ver si puedo coordinar y a dar una plática por allá. ¡Gracias! #RStats #RStatsES #ARNsec
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🇲🇽 Leonardo Collado-Torres @lcolladotor.bsky.social · 06/06/2026
We are cooking up a few research products and I can’t wait to share them with the wider neuroscience research community. Which photo should we use on the team website? lcolladotor.github.io #Bioconductor #RStats #DataScience #TeamPhoto #Neuroscience
lcolladotor.github.io
L. Collado-Torres
R/Bioconductor-powered Team Data Science
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🇲🇽 Leonardo Collado-Torres @lcolladotor.bsky.social · 06/06/2026
Thank you very much team for all your hard work and efforts this past year. The current science climate is challenging in the US, but within our little bubble at @lieberinstitute.bsky.social (the “Translational Neuroscience Division”), I’ve greatly enjoyed working with all of you.
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🇲🇽 Leonardo Collado-Torres @lcolladotor.bsky.social · 06/06/2026
New team photos! 2026 version with @mbarse.bsky.social, @lahuuki.bsky.social, @nick-eagles.bsky.social ^^. We also have remote member contributors 🗺️ (@daiannaglez.bsky.social, @melo-mq99.bsky.social, @gabrielramirezv.bsky.social, from LCG UNAM). Thank you @martinowk.bsky.social for hosting us!
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Robin Magnard @robinmagnard.bsky.social · 15/05/2026
Thrilled about our new @janaklab.bsky.social paper now out in @npp-journal.bsky.social🧠⚡ Action-sequence termination cues evoke mesolimbic dopamine activity that drives habit-like behavior. Thanks to Tricia Janak, @younavandaele.bsky.social, and @yfcheng.bsky.social! www.nature.com/articles/s41...
nature.com
Sequence termination cues drive automated habit-like strategy via dopamine-mediated processes - Neuropsychopharmacology
Neuropsychopharmacology - Sequence termination cues drive automated habit-like strategy via dopamine-mediated processes
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elizabethginexi.bsky.social @elizabethginexi.bsky.social · 29/05/2026
Summary of Key Changes in OMB’s Proposed Federal Financial Assistance Rule. Russell Vought is going destroy American Science. elizabethginexi.substack.com/p/summary-of...
elizabethginexi.substack.com
Summary of Key Changes in OMB’s Proposed Federal Financial Assistance Rule
Russell Vought is going destroy American Science
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🇲🇽 Leonardo Collado-Torres @lcolladotor.bsky.social · 26/05/2026
Si conocen a mexicano/as 🇲🇽 en @jhu.edu (o afiliada/os) y/o profesionistas en Baltimore, avísenme. Organizo un grupo de WA de mexas en Balto que estoy buscando revivir. Voy a aprovechar que estoy organizando una fiesta con mariachis 🎺 🎤 y así intentar fomentar nuestra pequeña comunidad. ¡Gracias!
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