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Jeff Leek

@jtleek.bsky.social
624 followers 79 following 45 posts

Dad/Coach Chief Data Officer, Fred Hutch hutchdatascience.org Professor, Fred Hutch jtleek.com Founder, Synthesize Bio www.synthesize.bio Building things to help people. Opinions & content are my own.

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Reposted by Jeff Leek
Fred Hutch Biostatistics Program @fredhutchbiostat.bsky.social · 15/03/2026
📣 TOMORROW! Stephen Salerno, Awan Afiaz, and @jtleek.bsky.social present "Scorcher: An R Package to Democratize Building and Fitting Torch Deep Learning Models." 🔥
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Jeff Leek @jtleek.bsky.social · 11/02/2026
Inference with predicted data is one of the hottest topics in statistics with many, many big names focusing on it. If you are interested in hearing about one of the hottest topics in the field from one of the best teachers I know - you should go to this! #ENAR2026
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Reposted by Jeff Leek
UW Biostatistics @uwbiostat.bsky.social · 18/12/2025
Check out @uwbiostat.bsky.social department contributions highlighted in the @uwsph.bsky.social 2025 impact report. sph.washington.edu/impact
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Jeff Leek @jtleek.bsky.social · 12/12/2025
We are really interested in hearing the trainee experience - would love to hear from any trainees about their interests and styles of learning! Check this out and please share!
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Reposted by Jeff Leek
itcrtraining.bsky.social @itcrtraining.bsky.social · 18/11/2025
The ITCR Training Network (ITN) www.itcrtraining.org develops training materials for informatics and research. We have a short survey ~3-9 min about your experience & preferences for learning as a researcher. Previous engagement not required! xiar7j-itn.shinyapps.io/itn_follow_up/
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Reposted by Jeff Leek
Stephen Turner @stephenturner.us · 31/10/2025
Ad hoc, post hoc and intrinsic-hoc in bioinformatics www.nature.com/articles/s41... (read free: rdcu.be/eNGd3) 🧬🖥️🧪
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Jeff Leek @jtleek.bsky.social · 24/09/2025
A cool story that connects the first data I ever analyzed to the work we are doing with Synthesize ! youtube.com/shorts/zN4_m...
youtube.com
The Experiments #Biology Can’t Run — Until Now. #AI #entrepreneur #technology #tech #geneexpression
YouTube video by Madrona
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Jeff Leek @jtleek.bsky.social · 16/09/2025
Generative genomics predicts future and impossible experiments! Read the new preprint from Synthesize Bio: www.biorxiv.org/content/10.1... and anyone can try our models on the cloud or in R/Python! product.synthesize.bio
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Reposted by Jeff Leek
Fred Hutch Biostatistics Program @fredhutchbiostat.bsky.social · 15/09/2025
CAIA is breaking down research silos with federated learning. AI models learn from diverse data without moving it. Read more: www.canceralliance.ai/blog/beyond-... Congrats to @jtleek.bsky.social + CAIA for advancing secure, equitable cancer research. #CancerAI #FederatedLearning #Biostatistics
canceralliance.ai
Research beyond silos - Cancer AI Alliance
The Cancer AI Alliance (CAIA) brings together top cancer centers and tech leaders to break down institutional silos. Using federated learning, they securely train AI models on diverse patient data, ac...
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Reposted by Jeff Leek
Johns Hopkins Engineering @hopkinsengineer.bsky.social · 02/09/2025
Our pioneering partnership with leading cancer centers and tech companies has been recognized by TIME magazine’s #TIME100AI 2025 for groundbreaking work in artificial intelligence and cancer research!
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Jeff Leek @jtleek.bsky.social · 28/08/2025
Honored to see the Cancer AI Alliance included on TIME's list of the TIME100 AI of 2025! #TIME100AI. CAIA has been a true team sport based on the shared commitment of all our Alliance members to accelerate cancer research and ultimately improve and save patient’s lives. time.com/collections/...
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Jeff Leek @jtleek.bsky.social · 27/08/2025
Check out this great post explaining our approach to enabling AI model learning and reasoning across multiple-institutions while carefully protecting (and never transferring!) patient data! www.canceralliance.ai/blog/caia-fe...
canceralliance.ai
How CAIA harnesses federated learning for secure collaboration - Cancer AI Alliance
How can we train AI models on the collective knowledge of the nation's top cancer centers without exposing sensitive patient information? CAIA’s solution is an AI training approach called federated ...
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Jeff Leek @jtleek.bsky.social · 19/08/2025
I was recently on a panel talking about Synthesize Bio and the future of AI in biotech! www.youtube.com/watch?v=AR5s...
youtube.com
The Future of Drug Discovery: AI, Data, and Design
YouTube video by Madrona
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Reposted by Jeff Leek
Fred Hutch @fredhutch.org · 08/08/2025
Fred Hutch data scientists Carrie Wright and Elizabeth Humphries weigh in on OpenAI's first open-weight reasoning #AI, noting its potential for personalization in research applications while emphasizing thoughtful integration. Via @nature.com go.nature.com/4mFSoRb @fredhutchbiostat.bsky.social
go.nature.com
OpenAI launches reasoning LLM that you can download and tweak
One version of the gpt-oss large language model can run on a laptop, and performs nearly as well as the company’s most powerful models.
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Jeff Leek @jtleek.bsky.social · 07/08/2025
Code from my first live R package demo talk in honor of Hadley at #jsm2025 gist.github.com/jtleek/8c927... Steve Salerno, Awan Afiaz, and I have been developing the scorcher package to help you more easily fit deep learning models in R ! github.com/jtleek/scorc...
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Jeff Leek @jtleek.bsky.social · 06/08/2025
The highlight of my #jsm2025 talk was @hadley.nz roasting the panel with ChatGPT.😂 I also love that he talked about aspiring to kindness!
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Jeff Leek @jtleek.bsky.social · 06/08/2025
We are about to be live talking about how cool @hadley.nz is in CC214 at 1030am ! Come hang out if you are at #jsm2025
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Jeff Leek @jtleek.bsky.social · 28/07/2025
My family and I are going to be running the 5k at Obliteride again this year! (we'll be biking as soon as the boys are old enough :)). We are raising funds for data science and AI efforts to find cancer cures at the Fred Hutch, consider donating if you are able! secure.fredhutch.org/site/TR/Obli...
secure.fredhutch.org
Jeff Leek
Help Fred Hutch Cancer Center advance innovative research. Donate today!
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Jeff Leek @jtleek.bsky.social · 23/07/2025
Wild congratulations to one of the most incredible people I’ve ever worked with. @benlangmead.bsky.social I hope you are celebrating this very well deserved honor!!!
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Jeff Leek @jtleek.bsky.social · 04/06/2025
These are not just grants. This is thousands of people who devoted their lives and careers - taking pay cuts, working long hours, living with uncertainty - all for the chance to try to make people's lives a bit better for you and your loved ones. This breaks my heart.
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Rob Patro @robp.bsky.social · 30/05/2025
Damn... I wonder why scientists wouldn't want to come to the US to compete at the highest levels for highly-restricted funding that then gets pulled surreptitiously for some imagined reason or no reason at all, all while being vilified by the federal government for their work? A mystery! 🤔
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Ben Langmead @benlangmead.bsky.social · 29/05/2025
Industry friends, now is the time for MUCH more speaking out on behalf of academic colleagues under duress. Here are core open source methods that many of your products doubtlessly depend on either directly or indirectly (see en.wikipedia.org/wiki/HMMER) being abruptly defunded. Make noise.
en.wikipedia.org
HMMER - Wikipedia
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Jeff Leek @jtleek.bsky.social · 28/05/2025
If you are around Seattle, see ya there :)
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Reposted by Jeff Leek
Alexandra Rink @alexandrarink79.bsky.social · 22/05/2025
Bright and early talk by @jtleek.bsky.social at the Princess Margaret Cancer Centre Grand Rounds on building and scaling AI engines in oncology.
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Jeff Leek @jtleek.bsky.social · 19/05/2025
NOOOOOOOOOOOOOOOOOOOOOO
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Mike Schatz @mikeschatz.bsky.social · 06/05/2025
Congratulations to the @jxtxfoundation.bsky.social scholarship winners for the 2025 Biology of Genomes conference @cshlnews.bsky.social! Learn more about their research and the scholarship program here: jxtxfoundation.org/news/2025-3-... #bog25
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Jeff Leek @jtleek.bsky.social · 02/05/2025
Synthesize Bio's platform is awesome as a teaching tool. In just a couple of minutes you can (a) find a dataset, (b) run a validated workflow like @mikelove.bsky.social's published EDA workflow, and (c) share with your friends: app.synthesize.bio/notebooks/3a...
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Reposted by Jeff Leek
Dr. Tom Lynch @hutchpresident.bsky.social · 02/05/2025
This alliance helps solve the key technical challenges that will enable us to securely use both #AI and massive computational power to find these breakthrough insights and save more lives. Congrats to the CAIA team on this well-deserved recognition! #oncsky
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Jeff Leek @jtleek.bsky.social · 02/05/2025
An incredible honor and the momentum is building for the Cancer AI Alliance. We have been hard at work behind the scenes - expect more public from us soon! @brianmbot.bsky.social (pictured) and the broader CAIA team are amazing and it is fantastic to see their work rewarded.
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Dr. Tom Lynch @hutchpresident.bsky.social · 30/04/2025
We are in a period of remarkable progress in cancer research and care. It’s critical that we don’t let near-term pressures immobilize us and lose sight of our long-term plans. Thanks to Becker’s Hospital Review for inviting me to share what's at stake. www.beckershospitalreview.com/oncology/ami...
beckershospitalreview.com
Amid federal funding uncertainty, cancer center leaders forge ahead - Becker's Hospital Review | Healthcare News & Analysis
Facing federal funding uncertainty, a looming workforce shortage and an increasingly aging patient population, cancer center leaders in the U.S. remain undeterred. Their focus remains, as it has for d...
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Jeff Leek @jtleek.bsky.social · 30/04/2025
Really excited about releasing our platform for integrating gene expression data - search for and easily integrate multiple datasets app.synthesize.bio/datasets, analyze them in Notebooks, and sign up for our beta for AI-generated gene expression data from experimental designs!
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Reposted by Jeff Leek
Candace Savonen @cansavvy.bsky.social · 29/04/2025
The beta version of Synthesize Bio is up! You can jump right to playing with data! - Pull ready-to-go publicly available gene expression data. - Play around with this data using notebooks. - Request access to the beta version of AI data generation. product.synthesize.bio!
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Jeff Leek @jtleek.bsky.social · 23/04/2025
This is beyond short sighted. www.science.org/content/arti... The Women’s Health Initiative is simultaneously a gold standard for how to do large scale research, a huge impact study, a long term investment, and one of the best resources for AI in science. I’m just gutted for everyone involved
science.org
NIH guts its first and largest study centered on women
The Women’s Health Initiative has produced numerous influential findings
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Reposted by Jeff Leek
Leonidas Platanias, MD @leonidasplatan1.bsky.social · 22/04/2025
Cancer mortality rates have been dropping because of NIH and NCI funded research to Universities. Without it there would be no new cancer treatments that save lives.
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Jeff Leek @jtleek.bsky.social · 22/04/2025
The Cancer AI Alliance (www.canceralliance.ai) is hiring for a full time Director of Operations role careers-fhcrc.icims.com/jobs/29460/c... This role will drive execution across legal, financial, research compliance, philanthropy, and business development.
careers-fhcrc.icims.com
Fred Hutchinson Cancer Center
Fred Hutch is dedicated to the elimination of cancer and related diseases as causes of human suffering and death.
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Reposted by Jeff Leek
Prasad Jallepalli, MD, PhD @prasad.bsky.social · 04/04/2025
www.nytimes.com/2025/04/03/o... Really important piece to share widely. Too many Americans don’t know how severe a threat this Administration poses to our scientific infrastructure, global leadership, and health security
nytimes.com
Opinion | The Uncertain Fate of the Young American Scientist (Gift Article)
Young researchers are choosing between staying in science and staying in the United States.
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Jeff Leek @jtleek.bsky.social · 04/04/2025
Excited to officially welcome Google and AI2 to the Cancer AI Alliance ! www.prnewswire.com/news-release... The alliance is enabling us to move at incredible speed and still being super careful about data thanks to the big collaborative team of experts!
prnewswire.com
Google Cloud and Ai2 Commit $20M to Advance AI-Powered Research for the Cancer AI Alliance
/PRNewswire/ -- Today, Google Cloud and Ai2 announced they have partnered with the Cancer AI Alliance (CAIA), a pioneering consortium uniting leading cancer...
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Jeff Leek @jtleek.bsky.social · 03/04/2025
Check out this awesome new R package for simplifying working with AWS from folks at @fredhutch.bsky.social recology.info/2025/04/sixt...
recology.info
sixtyfour: writing robust code against AWS
Introduction At work (Fred Hutch Cancer Center) we’ve been working on an R package (sixtyfour) over the last ~1.5 years. This post is a quick intro to the package with some learnings about working wit...
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Jeff Leek @jtleek.bsky.social · 31/03/2025
Public health biostatistics has always been incredibly important; but in this moment even more so! Consider nominating an early career biostatistician for our field's most prestigious award: www.spiegelmanaward.org by May 1! This is an opportunity to highlight how biostatistics helps so many people
spiegelmanaward.org
Mortimer Spiegelman Award
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Reposted by Jeff Leek
Wake Forest Statistical Sciences @wakeforeststats.bsky.social · 10/03/2025
👏 Huge congratulations to Assistant Prof @lucystats.bsky.social for her Emerging Leader Award from the Committee of Presidents of Statistical Societies!
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Jeff Leek @jtleek.bsky.social · 14/03/2025
Our Cancer AI Alliance is up for Health Innovation of the Year for the Seattle-based Geekwire awards! www.geekwire.com/events/2025-... @fredhutch.bsky.social is very proud to represent our Alliance - we'd love your vote for the hard work being done by all of the people involved!
geekwire.com
2025 GeekWire Awards
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Jeff Leek @jtleek.bsky.social · 06/03/2025
Watching one of the world’s leading scientists talk about one of the world’s most important studies; Garnet Anderson from @fredhutch.bsky.social reflecting on 30 years of the Women’s Health Initiative. Such an incredible force for good over 3+ decades
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Jeff Leek @jtleek.bsky.social · 24/02/2025
This is an incredibly important post by @rafalab.bsky.social on our Simply Statistics blog (its still around!) on why "indirect costs" are spent on research and its not enough! simplystatistics.org/posts/2025-0...
simplystatistics.org
Simply Statistics: Universities Do Spend Indirect Costs on Research, And It’s Still Not Enough
Many, including prominent scientists, seem to misunderstand the true cost of biomedical research and the fact that universities subsidize it beyond what they receive from the NIH.
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Jeff Leek @jtleek.bsky.social · 24/02/2025
Amazing work from a big collaborative group in publishing our ipd R package for doing inference after prediction. Are you making predictions with ML models? Then you should be using ipd! academic.oup.com/bioinformati... code here: github.com/ipd-tools/ipd
academic.oup.com
ipd: an R package for conducting inference on predicted data
AbstractSummary. ipd is an open-source R software package for the downstream modeling of an outcome and its associated features where a potentially sizable
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Jeff Leek @jtleek.bsky.social · 07/01/2025
This is an INCREDIBLE episode. I would say without exaggeration podcast episode of the year in #ai. It is a fully human centered view of the data that drives our models. Should be required listening for anyone who uses data about people in their work.
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Jeff Leek @jtleek.bsky.social · 07/01/2025
So excited about the huge possibilities of this public private partnership with our amazing colleagues in tech and across cancer centers!!
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Reposted by Jeff Leek
Denis Wirtz @deniswirtz.bsky.social · 17/12/2024
Hopkins is recruiting 30 Bloomberg Distinguished Professors in AI + X (X = astrophysics, cancer, neuroscience, genomics, social sciences, etc.) hub.jhu.edu/2024/12/17/d... 22 of these 30 will be organized in clusters that were selected after rigorous external review. The list of clusters is:
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Jeff Leek @jtleek.bsky.social · 12/12/2024
I think one low cost, high impact intervention to improve peer review is training trainees on what peer review should look like. I wrote this guide for my students: github.com/jtleek/reviews that includes an opinionated approach to what is/isn't important in review (pretty computationally flavored)
github.com
GitHub - jtleek/reviews: Writing reviews of academic papers
Writing reviews of academic papers. Contribute to jtleek/reviews development by creating an account on GitHub.
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BF Francis Ouellette @bffo.bsky.social · 04/12/2024
I know lots of requests on Tuesdays. Let me pitch in the one I did give to today, the @jxtxfoundation.bsky.social foundation for #OpenScience. Please give a little, a lot, and often, not just this Tuesday. Think about the #OpenScience minds that need 2 B encouraged! www.zeffy.com/donation-for...
zeffy.com
James P. Taylor Foundation for Open Science
Your donation will help provide support for graduate students to attend conferences in computational biology and data science, where they can present their work and form connections with other researc...
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Jeff Leek @jtleek.bsky.social · 04/12/2024
Check out this awesome new podcast "Cracking the Cancer Code" on the intersection of data/ai and cancer: crackingthecancercode.buzzsprout.com
crackingthecancercode.buzzsprout.com
Cracking the Cancer Code
In an age where data are everywhere, harnessing the power of data science can be a catalyst for groundbreaking discoveries in the fight against cancer. Welcome to the Cracking the Cancer Code podcast ...
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