Programmed −1 ribosomal frameshifting (PRF) is a translational control mechanism used by RNA viruses to regulate the relative abundance of proteins en…

F1-ATPase is a rotary motor protein essential for cellular energy transduction. Here the authors develop a thermodynamically consistent Markov model that quantitatively matches experimental data and r...

CliM is a ribosome arrest peptide in Clostridia. Here, the authors show that CliM adopts helices and extensively interacts with the ribosome. The penultimate residue sterically blocks A-site accommoda...

This Perspective discusses current challenges in macromolecular ensemble prediction and the infrastructure and methodological advances needed to overcome these barriers.

Ubiquitin coordinates a complex network of cellular pathways through covalent modification of substrates. Specificity in substrate recognition and modification choice is largely conferred by ubiquitin...

Recent high-throughput applications to shotgun proteomics have shown great benefits of coupling ion mobility spectrometry (IMS) to mass spectrometry. IMS adds a separation dimension by differentiating...

Abstract. Recently, a tRNATrpCCA with a 4-base-pair (bp) anticodon stem (AS) was shown to efficiently recognize a near-cognate UGA codon in unicellular euk

We are looking for a highly motivated and dynamic computational postdoc for a 3-year position to join the Lund Group. Our research Our team aims to understand h

🚨Due to the regime cutting off the internet last 5 days messages coming out of Iran have decreased by 99% - this one made it through. The scale of civilian massacre is far beyond what has been reported. The figure of 12,000 killed is described as ‘almost a joke’ compared to the magnitude of the catastrophe that has taken place.The regime in Iran have carried out widespread and systematic deadly violence. “It is a massacre beyond human imagination”. There are subtitles so please go to the end. It is still happening. Please share widely.#IranianRevolution2026

MINFLUX microscopy allows for localization of fluorophores with nanometer precision by using targeted scanning with an illumination profile with a minimum. However, current scanning patterns and the o...

Annual conference on Free Energy Methods in Drug Discovery

The group studies the relationship between dynamics and function of biological macromolecules at the atomic level using computer simulations. Modern, sophisticated techniques are employed to follow the motions of atoms and molecules at timescales of femtoseconds to microseconds, thereby providing insight into the functional mechanism of e.g. enzymesand transport proteins. The main research focus lies on permeation events in membrane channels like aquaporins or gramicidin, collective and functionally essential modes of motion in enzymes, and the development of novel simulation techniques as an alternative to conventional simulation methods.