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Michael Koeris

@koeris.bsky.social
534 followers 53 following 50 posts

Director of the Office of Biological Technologies of DARPA

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Reposted by Michael Koeris
Mick Ryan @warinthefuture.bsky.social · 31/12/2025
On 29 December, just as the summit between Zelenskyy and Trump was finishing at Mar-a-lago, the PLA Eastern Theatre Command announced that it had commenced exercise "Justice Mission 2025" in the Taiwan Strait. I have just published an assessment of the exercise. mickryan.substack.com/p/justice-mi...
mickryan.substack.com
Justice Mission 2025 is a Golden Opportunity to Learn about PLA Joint Planning and Capabilities
A special assessment of China's Exercise Justice Mission 2025, what China designed it to achieve, and how we can learn from it.
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Reposted by Michael Koeris
STAT @statnews.com · 18/10/2025
Kyle Muldoon thought he might never get to watch an Eagles game with his son KJ, who was born with a rare and fatal liver disease that was treated with an individual CRISPR therapy. #STATSummit
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Michael Koeris @koeris.bsky.social · 14/06/2025
The Defense Advanced Research Projects Agency BTO (us!!!) is seeking disruptive solutions to defend U.S. agriculture (crops and livestock) against chemical/biological threats! darpa.mil/research/progr…
darpa.mil
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Reposted by Michael Koeris
Institute for the Study of War @thestudyofwar.bsky.social · 14/06/2025
ISW is seeking a full-time Middle East Security Program Researcher to provide timely open-source research and analysis of the geo-strategic dynamics of the Middle East region and how those dynamics will affect U.S. national security interests. For more info & to apply: isw.pub/MiddleEastRe...
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Reposted by Michael Koeris
Institute for the Study of War @thestudyofwar.bsky.social · 09/05/2025
4/ PRC is possibly conducting bathymetric surveys in the strategically significant Luzon Strait between Taiwan and the Philippines.
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Reposted by Michael Koeris
Financial Times @financialtimes.com · 24/03/2025
Indonesia names Ray Dalio and Jeffrey Sachs as sovereign wealth fund advisers www.ft.com/content/d90a401b-d086-44…
ft.com
Indonesia names Ray Dalio and Jeffrey Sachs as sovereign wealth fund advisers
Investors voice concern over governance at fund expected to manage state assets
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Reposted by Michael Koeris
Addgene @addgene.bsky.social · 11/03/2025
Check out our latest Hot Plasmids post, featuring cool new tools like self-labeling constructs from @dozenoaks.bsky.social, an improved voltage sensor from @michaelzlin.bsky.social, prime editing in dicot plants, and more! blog.addgene.org/hot...
blog.addgene.org
Hot Plasmids: Winter 2025
Check out the latest Hot Plasmids, viral vectors, and antibodies in the Addgene repository!
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Reposted by Michael Koeris
Addgene @addgene.bsky.social · 11/03/2025
pcDNA3-Y392C-WLS-HA-IRES-GFP Depositor: Joseph Gleeson Purpose: Expression of WLS-HA protein (Y392C mutant) www.addgene.org/178062/
Plasmid of the Day
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Reposted by Michael Koeris
Financial Times @financialtimes.com · 08/03/2025
‘Game changer’: German spending plans lift bond market’s growth forecasts www.ft.com/content/f54f6eb2-5858-44…
ft.com
‘Game changer’: German spending plans lift bond market’s growth forecasts
Chancellor-in-waiting Merz’s promise to do ‘whatever it takes’ pushes Bund yields sharply higher in anticipation of more issuance
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Reposted by Michael Koeris
Financial Times @financialtimes.com · 24/02/2025
Europe needs Friedrich Merz to succeed | Opinion www.ft.com/content/61eef114-b42d-45…
ft.com
Europe needs Friedrich Merz to succeed | Opinion
The first moves by Germany’s chancellor-designate are bold and encouraging
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Reposted by Michael Koeris
Financial Times @financialtimes.com · 19/02/2025
Big Tech’s AI ambitions deliver funding boost to nuclear reactor race www.ft.com/content/2d84198e-7eeb-41…
ft.com
Big Tech’s AI ambitions deliver funding boost to nuclear reactor race
Developers of advanced microreactors have raised at least $1.5bn over the past year as demand soars
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Michael Koeris @koeris.bsky.social · 19/02/2025
Fantastic work by @kexinhuang.bsky.social at Stanford (arXiv: 2502.09858) Validation of hypotheses for experimental planning and verification based on the falsification principle by Karl Popper. The Future just most a lot closer!!!
github.com
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Reposted by Michael Koeris
STAT @statnews.com · 14/02/2025
Michael Lauer, deputy director of the National Institutes of Health’s extramural research, will leave the agency at the end of the week.
buff.ly
Second top NIH official, who oversaw awarding of research grants, departs abruptly
Michael Lauer, deputy director of the National Institutes of Health’s extramural research, will leave the agency at the end of the week.
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Michael Koeris @koeris.bsky.social · 13/02/2025
It’s been a tough few years. But innovation doesn’t stop. Science still advances, improvements and breakthroughs will still happen. The pace is different but it’s not gone. I know it’s tough to see @adamfeuerstein.bsky.social and we at DARPA BTO still believe & will get after it. #stayInTheFight
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Reposted by Michael Koeris
Addgene @addgene.bsky.social · 13/02/2025
Ready to jump into base editing? Check out our updated CRISPR 101 blog post "Cytosine and Adenine Base Editors"! blog.addgene.org/sin...
blog.addgene.org
CRISPR 101: Cytosine and Adenine Base Editors
An overview of cytosine and adenine base transition editors, which make precise changes in DNA bases without causing double-strand breaks.
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Reposted by Michael Koeris
Michael Koeris @koeris.bsky.social · 06/02/2025
We're hiring here at DARPA! A "Program Manager" is effectively an intrapreneur and we're going after Synthetic Biology #SynBio super hard. Please fwd to interested people! www.linkedin.com/posts/mkoeri...
linkedin.com
Michael Koeris on LinkedIn: Thank you Jeffrey S. Buguliskis for the interview and patience as I go on…
Thank you Jeffrey S. Buguliskis for the interview and patience as I go on and on about SCIENCE and of course especially Synthetic Biology! Many sciences are…
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Reposted by Michael Koeris
Addgene @addgene.bsky.social · 06/02/2025
🎉🎉 Congrats! 🥳 If you're interested in unveiling the NATURA way, you can find the plasmids here: www.addgene.org/browse/artic...
addgene.org
Addgene: Unveiling Sequence-Agnostic Mixed-Chemical Modification Patterns for SpliceSwitching Oligonucleotides using the NATURA platform
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Reposted by Michael Koeris
Adam Feuerstein✡️ @adamfeuerstein.bsky.social · 06/02/2025
The CRISPR companies are not OK Today, in @statnews.com - a must-read story from my colleague @jasonmast.bsky.social www.statnews.com/2025/02/06/c...
statnews.com
The CRISPR companies are not OK
Gene editing promised a revolution, but biotech layoffs, stock slumps, and industry struggles reveal a stark reality: CRISPR is hard to do profitably.
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Michael Koeris @koeris.bsky.social · 06/02/2025
We're hiring here at DARPA! A "Program Manager" is effectively an intrapreneur and we're going after Synthetic Biology #SynBio super hard. Please fwd to interested people! www.linkedin.com/posts/mkoeri...
linkedin.com
Michael Koeris on LinkedIn: Thank you Jeffrey S. Buguliskis for the interview and patience as I go on…
Thank you Jeffrey S. Buguliskis for the interview and patience as I go on and on about SCIENCE and of course especially Synthetic Biology! Many sciences are…
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Reposted by Michael Koeris
Tom Ellis @proftomellis.bsky.social · 06/02/2025
What happens to bacterial genomes when they're cloned into yeast? Do they transcribe, do they get silenced, do they get packaged away from the rest of the DNA? This cool study congrats to the Koszul lab team at Pasteur for this great work. www.science.org/doi/10.1126/...
science.org
Sequence-dependent activity and compartmentalization of foreign DNA in a eukaryotic nucleus
In eukaryotes, DNA-associated protein complexes coevolve with genomic sequences to orchestrate chromatin folding. We investigate the relationship between DNA sequence and the spontaneous loading and a...
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Michael Koeris @koeris.bsky.social · 04/02/2025
Very excited to have The New Yorker cover the #FSHARP program we've been running here at @DARPA! Synthetic blood analog that is shelf-stable and mass manufacturable to deal with all blood shortages whether for warfighters or in the civilian medical world! t.co/41zItaHSpb
t.co
https://www.newyorker.com/magazine/2025/02/10/the-long-quest-for-artificial-blood
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Reposted by Michael Koeris
C&EN (Chemical & Engineering News) @cenmag.bsky.social · 02/02/2025
Helicore Biopharma has emerged from stealth with $65 million in series A financing to clinically test its lead drug candidate, an injectable for weight loss and related conditions. cen.acs.org/business/sta... 🧪 #scinews #biosky
cen.acs.org
Weight-loss start-up emerges from stealth
Unlike popular GLP-1 agonists, Helicore’s lead asset targets GIP receptors
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Reposted by Michael Koeris
Scott Gottlieb, MD @scottgottliebmd.bsky.social · 29/01/2025
statnews.com
Former surgeon general: Vaccine-preventable diseases are still a major threat
“You can’t die of heart disease at 50 if you died of polio at 5,” Jerome Adams, former surgeon general, warns.
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Michael Koeris @koeris.bsky.social · 26/01/2025
Ohhhhh 👀
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Reposted by Michael Koeris
Institute for the Study of War @thestudyofwar.bsky.social · 26/01/2025
NEW: Israel announced on Jan. 25 that it will prevent Palestinians from returning to northern Gaza because Hamas violated the ceasefire agreement. Reuters reported that Hamas has recruited between 10,000 to 15,000 fighters since the start of the Israel-Hamas war. isw.pub/IranUpdate01... More 🔽
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Reposted by Michael Koeris
Financial Times @financialtimes.com · 25/01/2025
CIA says that Covid-19 probably leaked from Chinese laboratory www.ft.com/content/9880273c-8517-45…
ft.com
CIA says that Covid-19 probably leaked from Chinese laboratory
The US intelligence agency has changed its assessment of the likely origins of the pandemic
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Reposted by Michael Koeris
Financial Times @financialtimes.com · 23/01/2025
Sam Altman-backed Retro Biosciences to raise $1bn for project to extend human life www.ft.com/content/25a473ea-9f87-47…
ft.com
Sam Altman-backed Retro Biosciences to raise $1bn for project to extend human life
The San Francisco-based start-up plans to get its first drug into trials this year
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Michael Koeris @koeris.bsky.social · 21/01/2025
Yes
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Reposted by Michael Koeris
Simon Bayly @simonbayly.bsky.social · 21/01/2025
Putting this cat amongst the #chemsky pigeons...
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Reposted by Michael Koeris
Financial Times @financialtimes.com · 20/01/2025
Hedge fund managers pocket nearly half of investment gains as fees www.ft.com/content/d66e183c-6d0d-45…
ft.com
Hedge fund managers pocket nearly half of investment gains as fees
Industry has taken $1.8tn in charges since the 1960s, according to LCH research
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Michael Koeris @koeris.bsky.social · 18/01/2025
🤣🤣🤣🤣🤣🤣🤣
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Reposted by Michael Koeris
Uncle Duke @uncleduke1969.bsky.social · 18/01/2025
"What happened?" "I’m stuck. It's so embarrassing." “I guess things went... a-rye?” “Please do shut up.” "You should get out of the sun." "Why?" "Otherwise, you'll be toast." "You're an asshole, Charlie." “You’re right, you deserve butter.”
Two seagulls walking. One’s beak is stuck through a slice of bread.
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Michael Koeris @koeris.bsky.social · 18/01/2025
Looks like a bunker buster …
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Reposted by Michael Koeris
Max Planck Institute of Biophysics @mpibp.bsky.social · 17/01/2025
Fresh out of the press! ✨Check out our new paper on the violent entry of the HIV capsid into the nuclear pore — and how it cracks the gate! 🤯 💥 Incredible work from @becklab.bsky.social and @hummerlab.bsky.social 🤩 More here: www.biophys.mpg.de/2842024/hivcapsid-cracks-the-npc?c=2011019 🔗 #teamTOMO
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Reposted by Michael Koeris
Scott Gottlieb, MD @scottgottliebmd.bsky.social · 18/01/2025
I’ll be on @cnbc.com Monday from the inauguration booth with host Becky Quick discussing the Trump Administration’s healthcare agenda, coming policy changes, and the outlook for innovation and continued advances in life sciences. #TrumpInauguration
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Reposted by Michael Koeris
Scott Gottlieb, MD @scottgottliebmd.bsky.social · 17/01/2025
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Michael Koeris @koeris.bsky.social · 12/01/2025
Listen to what the doctor is prescribing everyone. Safety and security starts with (disease) surveillance. We have to move and vigorously monitor our national bio-intelligence perimeter.
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Reposted by Michael Koeris
Frances Arnold @francesarnold.bsky.social · 12/01/2025
Hell continues in #LosAngeles with the #LAfires. I live next to #Altadena, which is pretty much destroyed. My power finally came on after three cold nights. So many have lost their homes, and danger not over since big winds are coming back starting tomorrow. Views at my house Wednesday early am.
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Reposted by Michael Koeris
Financial Times @financialtimes.com · 03/01/2025
Germany debates menace of ‘firework bombs’ after New Year’s violence www.ft.com/content/9eaebd08-b00d-49…
ft.com
Germany debates menace of ‘firework bombs’ after New Year’s violence
Deaths and clashes with police mar celebrations, with officials calling for tougher curbs on use of powerful fireworks
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Reposted by Michael Koeris
Financial Times @financialtimes.com · 03/01/2025
Recovery in US car sales eases fear of economic malaise settling in www.ft.com/content/00420e5d-ae16-45…
ft.com
Recovery in US car sales eases fear of economic malaise settling in
Strong purchase data to end the year reverses downward trend as lower interest rates and better deals lure buyers
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