iiinova — where your digital self keeps evolving

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Gozde Demirer @prof-gozde.bsky.social · 16/05/2026

Caltech Chemical Engineering is recruiting a long-term lecturer! Reach out if you’re interested and have any questions. applications.caltech.edu/job/chemeng

applications.caltech.edu

Long-Term Lecturer in Chemical Engineering | Caltech Applications

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Peter to the Ploeg 𓆚 @pvdp.eurosky.social · 24/04/2026

Ik sprak Nobelprijswinnaar Frances Arnold! Zij laat in haar baanbrekende onderzoek naar de perfecte enzymen evolutie het werk doen: ‘Je kunt veertig jaar proberen enzymen te ontwerpen, maar de natuur wéét hoe je iets moet ontwerpen’ 🎁: www.nrc.nl/nieuws/2026/...

nrc.nl

Frances Arnold laat evolutie het werk doen: ‘Je kunt veertig jaar proberen enzymen te ontwerpen, maar de natuur wéét hoe je iets moet ontwerpen’

Frances Arnold | biochemicus: Enzymen kun je zien als de startkabels van de natuur. Frances Arnold, voormalig adviseur van president Joe Biden, kreeg in 2018 een Nobelprijs voor haar werk om deze eiwi...

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The Onion @theonion.com · 17/04/2026

“According to our observations over the past 24 hours, the vast majority of species on earth have pretty much just been holding steady and staying the course, gene-wise,” said biologist Clarice Abernathy

theonion.com

Biologists Confirm Not Much Evolution Happened Today

STANFORD, CA—Calling it a “pretty slow one” as far as natural selection and genetic drift were concerned, biologists from Stanford University confirmed Tuesday that not much evolution happened today. ...

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Alex Tong @alextong.bsky.social · 08/04/2026

Such an incredible journey building DISCO 🪩. Love working with this team. DISCO is a co-design model with functional, de novo, new-to-nature enzymes. Huge shoutout to my co-authors for making this a reality! 🚀👇

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Marta Skreta @martaowesyou.bsky.social · 08/04/2026

What if AI could invent enzymes that nature hasn’t seen? 👩‍🔬🧑‍🔬 Introducing 🪩 DISCO: Diffusion for Sequence-structure CO-design 📝 Blog: disco-design.github.io 📄 Paper: arxiv.org/abs/2604.05181 💻 Code: github.com/DISCO-design...

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Michael Peel @mikepeeljourno.bsky.social · 21/02/2026

Nobel laureate Frances Arnold has had an extraordinary journey from teenage rebellion in Pittsburgh to harnessing AI to evolutionary biology to create new kinds of chemistry. I sat down with her for a Lunch with the FT in the bistro of Stockholm's Nobel Prize Museum. www.ft.com/content/9923...

ft.com

Nobel chemistry laureate Frances Arnold: ‘Whole swaths of science are just going to die on the vine’

The Caltech professor on using AI to harness the power of enzymes — and what US funding cuts could mean for research

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Théophile Lambert @tlambert99.bsky.social · 17/02/2026

New work in Nature Communications! Using generative AI, we designed TrpB enzymes that are not only functional, but outperform natural ones and rival top lab-evolved TrpBs. www.nature.com/articles/s41... Huge thanks to @francesarnold.bsky.social, @anima-anandkumar.bsky.social, and all co-authors!

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Christopher Michel @christophermichel.com · 10/02/2026

One of the quiet failures of our time is how rarely we humanize science. We celebrate breakthroughs, but often lose sight of the people behind them. When science feels abstract, it becomes easy to dismiss or distrust it. That's why New Heroes exists www.explorers.com @nationalacademies.org #SciArt

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Anima Anandkumar @anima-anandkumar.bsky.social · 16/12/2025

An exciting collaboration with @francesarnold.bsky.social on AI+enzymes. This combines generative protein models with carefully tuned filters that resulted in functional and versatile enzymes beating natural and previously engineered enzymes.

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Frances Arnold @francesarnold.bsky.social · 16/12/2025

Generated PLP-dependent Trp synthases are functional, stable, and exhibit usefully broad substrate scopes! fun collaboration with @anima-anandkumar.bsky.social @ramanathanlab.bsky.social Amin Takavoli. I love AI + #enzymes!

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Kevin K. Yang 楊凱筌 @kevinkaichuang.bsky.social · 12/12/2025

Enzyme Engineering Database (EnzEngDB): a platform for sharing and interpreting sequence–function relationships across protein engineering campaigns @francescazfl.bsky.social @jsunn-y.bsky.social @francesarnold.bsky.social @arianemora.bsky.social Paper: doi.org/10.1093/nar/... DB: enzengdb.org

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Frances Arnold @francesarnold.bsky.social · 19/10/2025

Friday night at Adams pack station. 9 miles and a century from @caltech.

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Chemistry World @chemistryworld.com · 19/10/2025

A new round of layoffs at Nasa’s jet propulsion lab will result in ‘an untold loss of scientific knowledge and expertise’ according to congresswoman Judy Chu.

chemistryworld.com

Nasa’s Jet Propulsion Lab and home of Mars rovers loses 10% of its staff

The dismissal of 550 JPL workers is the fourth round of recent layoffs at the lab, prompting fears of a brain drain

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Frances Arnold @francesarnold.bsky.social · 08/09/2025

Looking for PhD or postdoctoral opportunities in #AI+biology #proteinengineering? the brilliant @arianemora.bsky.social has joined @aithyra.bsky.social in beautiful #vienna. I wish I could start over again!

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Frances Arnold @francesarnold.bsky.social · 04/09/2025

Our new paper on AI-generated TrpBs with @anima-anandkumar.bsky.social. GenSLM generated very useful promiscuous TrpB #enzymes, bypassing a lot of #directedevolution! great work by the whole team, especially Theophile Lambert. www.biorxiv.org/content/10.1...

biorxiv.org

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Kevin K. Yang 楊凱筌 @kevinkaichuang.bsky.social · 03/09/2025

A compelling review of how ML/AI could help in the quest to find an enzyme for every reaction. @jsunn-y.bsky.social @francescazfl.bsky.social Yueming Long @francesarnold.bsky.social www.cell.com/cell-systems...

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Frances Arnold @francesarnold.bsky.social · 03/09/2025

Private tour of the Louvre is a special treat. They were vacuuming the Sphinx. You may not have seen a Sphinx being brushed, so I am sharing.

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Frances Arnold @francesarnold.bsky.social · 10/08/2025

On the beautiful @Caltech campus with two new professors @reisenbauerlab.bsky.social and @arianemora.bsky.social headed to start their careers in Vienna. Prospective graduate students take note! This is the future of #enzymes #proteinengineering. @caltechcce.bsky.social @caltech.edu

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Frances Arnold @francesarnold.bsky.social · 31/07/2025

Loved seeing so many former #Arnoldgroup members at GRC #ProteinEngineering this week! Protein engineering is in good hands.

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Frances Arnold @francesarnold.bsky.social · 12/07/2025

I saw it firsthand at the Lindau Nobel Laureates meeting--international young scientists welcomed and recruited in Germany and elsewhere. www.wsj.com/politics/pol...

wsj.com

America’s Brain Drain Could Become the World’s Brain Gain

Research-funding cuts and immigration changes threaten some of America’s economic advantages.

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imbb-forth.bsky.social @imbb-forth.bsky.social · 02/07/2025

📅July 7-11 The 2025 Onassis Lectures in Biology and Chemistry will be held @forth-ite.bsky.social, Heraklion, Crete. This year’s Lectures are devoted to the advances, challenges, and future prospects of #Re-engineeringBiology through #DirectedEvolution and #Synthetic cellular pathways.

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Stephan Hammer @stephanhammer.bsky.social · 27/06/2025

Join us! We are looking for a new team member (PhD student) with strong background in organic chemistry. 🙏 RETWEET (We want to recruit internationally) Organic chemistry meets #DirectedEvolution Highly interdisciplinary & passionate research group uni-bielefeld.hr4you.org/job/view/433...

uni-bielefeld.hr4you.org

Research Position (PhD) in organic chemistry and b...

<div style="text-align: justify;">The  research  group  „Organic  Chemistry  and&nb...

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Frances Arnold @francesarnold.bsky.social · 27/06/2025

Really enjoying #Repartzymes Repurposed and Artificial Enzymes meeting organized by #TomWard of Uni. Basel. Many former group members are here! rep.artzymes.info

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Frances Arnold @francesarnold.bsky.social · 25/06/2025

I'm honored to be involved in the SDSS @stanforddoerr.bsky.social --we need it now more than ever. Let's continue to be bold about building the future.

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Kevin K. Yang 楊凱筌 @kevinkaichuang.bsky.social · 22/05/2025

Steered generation for protein optimization: On datasets with ~10^2 measurements, steering a discrete diffusion model outperforms RL on a protein language model for generating improved variants. @jsunn-y.bsky.social @francesarnold.bsky.social @yisongyue.bsky.social arxiv.org/abs/2505.15093

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Frances Arnold @francesarnold.bsky.social · 30/03/2025

Took a walk in the woods this weekend. So good for the soul.

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Frances Arnold @francesarnold.bsky.social · 27/03/2025

Such a pleasure to gather with current and former Arnold group members in San Diego! Thank you one and all. #ACSSpring2025

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Frances Arnold @francesarnold.bsky.social · 25/03/2025

My @acs.org Priestley award address can be found here fhalab.caltech.edu/wp-content/u...

fhalab.caltech.edu

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Frances Arnold @francesarnold.bsky.social · 25/03/2025

I got to tell some stories I don't usually include in science talks. Thank you for coming. I will post the address on my website soon.

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C&EN (Chemical & Engineering News) @cenmag.bsky.social · 13/03/2025

Meet @francesarnold.bsky.social, 2025 Priestley Medalist, at #ACSSpring2025. Stop by the ACS Booth Theater in the Expo Hall to hear about her contributions to #chemistry and pick up a signed copy of her C&EN feature issue. RSVP: connect.discoveracs.org/cen-priestle... #chemsky

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Will Thomas @williamthomas.bsky.social · 20/01/2025

Also remember that the National Archives maintains prior administrations' websites, e.g., bidenwhitehouse.archives.gov. I spent a lot of time unnecessarily downloading the Obama-era OSTP archive in 2017.

bidenwhitehouse.archives.gov

The White House

President Biden and Vice President Harris promised to move quickly to deliver results for working families. That’s what they’ve done.

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Frances Arnold @francesarnold.bsky.social · 20/01/2025

The White House website has been wiped clean, but thanks to @erichorvitz.bsky.social , all the Biden #PCAST reports are available below. I want to thank the #PCAST members, all of whom donated their time and expertise to helping policy be science-based. tinyurl.com/2acnv2nh

tinyurl.com

PCAST Reports (2020-2025)

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Jason Yang @jsunn-y.bsky.social · 16/01/2025

Happy to share that our work on Active Learning-Assisted Directed Evolution is now published in @naturecomms.bsky.social! Paper: www.nature.com/articles/s41... Check out the original thread here: x.com/jsunn_y/stat...

x.com

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Frances Arnold @francesarnold.bsky.social · 12/01/2025

Hell continues in #LosAngeles with the #LAfires. I live next to #Altadena, which is pretty much destroyed. My power finally came on after three cold nights. So many have lost their homes, and danger not over since big winds are coming back starting tomorrow. Views at my house Wednesday early am.

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Frances Arnold @francesarnold.bsky.social · 09/01/2025

#eatonfire near me. So many have lost their homes. Power is out and I am drinking the best wine.

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Frances Arnold @francesarnold.bsky.social · 05/01/2025

Many congratulations to #PCAST members Paula Hammond and John Dabiri for #NMS National Medal of Science and #NMTI National Medal of Technology and Innovation. These fabulous scientists are using #science and #technology in service of the nation and the world. www.whitehouse.gov/briefing-roo...

whitehouse.gov

President Biden Honors Nation’s Leading Scientists, Technologists, and Innovators | The White House

Today, President Biden announced the latest recipients of the National Medal of Science and the National Medal of Technology and Innovation—our nation’s

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Caltech Division of Chemistry and Chemical Engineering @caltechcce.bsky.social · 03/01/2025

Please join us in welcoming our newest Professor of Chemistry, Sandeep Sharma! 👋 His group's research eﬀorts are directed towards developing algorithms that solve the problem of electronic structure theory. He loves to spend time with his family and enjoys playing racket sports. Welcome, Sandeep!

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Laura Kiessling @laurakiessling.bsky.social · 04/01/2025

Just listened to a fantastic talk on harnessing evolution to do new #chemistry by @francesarnold.bsky.social at the Bowei Research Conference in Taiwan. Loved her advice: “Nature does not care about your calculations.”

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Frances Arnold @francesarnold.bsky.social · 03/01/2025

My grandson did not enjoy this juice. But he loved the vending machine.

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Frances Arnold @francesarnold.bsky.social · 31/12/2024

Happy 2025 to all! Crazy to watch a whole building erupt...

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Paul S. Weiss @pswnano.bsky.social · 24/12/2024

A pride of lions with seven cubs and three lionesses in Serengeti National Park in Tanzania, with Anne & @francesarnold.bsky.social

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Frances Arnold @francesarnold.bsky.social · 24/12/2024

Wishing you a Merry Christmas. I am spending mine with my three #cheetah brothers. The world is a wonderful place, full of quirks and treasures of #evolution.

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