STANFORD, CA—Calling it a “pretty slow one” as far as natural selection and genetic drift were concerned, biologists from Stanford University confirmed Tuesday that not much evolution happened today. ...

Rapid & standardized genome annotation using protein structural information - gbouras13/baktfold

Nature Biotechnology - A long-read metagenome assembly method recovers circular and complete genomes better than existing tools.

Long-read sequence assemblies from metagenomes contain frequent errors.

A newly compiled atlas of species-wide structural variants and gene-based and graph pangenomes derived from highly complete assemblies of genomes from 1,086 natural isolates enable integrative genome-...

Bifidobacterium are beneficial members of the microbiota across animal hosts. Kujawska et al. demonstrate that bifidobacteria have likely co-evolved more closely with mammals, particularly primates, a...

The authors sequence and phenotype over 1,000 isolates of the yeast Brettanomyces bruxellensis, and show how allopolyploidization reshapes genome evolution and enhances phenotypic diversity, highlight...

The human skin microbiome is increasingly recognized to influence skin health, immune function and disease susceptibility. However, large-scale, multi-site metagenomic studies in the general populatio...

Genomes from metagenomes have revolutionised our understanding of microbial diversity, ecology, and evolution, propelling advances in basic science, biomedicine, and biotechnology. Assembly algorithms...

: Hallucinated package names fuel 'slopsquatting'

Nature Methods - Phylogenetic compression achieves performant and lossless compression of massive collections of microbial genomes, facilitating fast BLAST-like search and versatile alignment tasks.

A tool for generating consensus long-read assemblies for bacterial genomes - rrwick/Autocycler

Creating mirrored organisms using synthetic biology could seriously harm extant life, a 300-page report claims. While the risks from mirrored life are uncertain, it is best not to find out.

The Central Dogma is not a

The discovery of synthetic xeno-nucleic acids (XNAs) that can basepair as unnatural bases (UBs) to expand the genetic alphabet has spawned interest in many applications, from synthetic biology to DNA ...

Engineered microbes can detect harmful chemicals, but may not work well in complex environments. Here, the authors built microbial sensors for detection of TNT explosive and tested their response over...

Strain richness of gut microbiota ecosystems is a key characteristic underpinning engraftment in faecal microbiota transplantation, and could improve the design of defined live biotherapeuti...

Non-human-associated microbial communities play important biological roles, but they remain less understood than human-associated communities. Here, we assess the impact of key environmental sample pr...

A tiny fern has a genome 50 times larger than a human’s. Energy and diffusion—not the nucleus volume—are the key bottlenecks to more expansive growth.

I’m posting this question, and an answer, to help dispel a few misunderstandings about what p-values are. As a hiring manager interviewing mid-level and senior data scientists, I have noticed these

Alignment-free SNP calling from metagenomes reduces computational time by two orders of magnitude.