By Dr. Douglas R. Waverly, Professor Emeritus of Biochemistry, Yale University

Nuciforo et al. establish a biopsy-derived organoid biobank spanning the clinical diversity of liver cancer and use large-scale phenotypic screening to build rational drug combinations. Because the combined agents act through complementary mechanisms, triplet therapies remain effective across heterogeneous tumors, with in vivo efficacy and favorable tolerability supporting translational potential.

BETHESDA, MD—The National Institutes of Health announced Tuesday that it would replace its 50-year-old numerical scoring system with a streamlined three-emoji format, in which grant applications will ...

Dolly Parton’s Imagination Library is a book gifting program that mails free books to children from birth until they begin school in participating areas.

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Sincere disagreements about AI are usually disagreements about future AI capabilities.

The kidney proximal tubule undergoes dramatic cell-state transformations during recovery from injury, serving as a unique model to study the dynamic t…

Michael Kratsios, President Trump’s science adviser, proposed overhauling how the government funds research. Democrats said Mr. Trump’s actions had weakened science.

COMBINE-lab develops algorithms, data structures, and software for high-throughput genomics.

Office of Management and Budget Director Russell Vought has poured gas on the foundations of science. Pharma CEOs should demand that President Donald Trump...

At public and private universities across the country, high-impact science is being damaged and derailed.

The metabolite αKG promotes carnitine synthesis and increases site-specific histone acetylation, thereby promoting homologous recombination-mediated DNA repair, which has potential implications f...