iiinova — where your digital self keeps evolving

Michael Guertin @guertin.bsky.social · 23/09/2026

Can we stop using the term "axis" in papers/grants/seminars? I have no idea what it means when you say the p53/CBP cancer axis

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Reposted by Michael Guertin

Seychelle Vos @voslab.org · 08/09/2026

⚡Preprint alert⚡ So proud of @amohamed98.bsky.social! Abdallah determined the cryo-EM structure of BRD4 bound to the kinase P-TEFb, defining the molecular basis of this key transcription interaction — and revealing that BRD4 and AFF4 binding are mutually exclusive to P-TEFb. Lots more inside 👇

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Michael Guertin @guertin.bsky.social · 30/08/2026

As an enlisted Airman in the early aughts, I often said “I support the war, but not the troops” as a comical response to the reciprocal trite saying. It took over 20 years, but now the highest levels of the government have adopted this as their official stance

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Michael Guertin @guertin.bsky.social · 21/07/2026

Registration for this mechanisms of RNA Polymerase regulation meeting is Aug 2: u.osu.edu/mltermmeeting/

u.osu.edu

Mountain Lake Termination Meeting

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Michael Guertin @guertin.bsky.social · 20/06/2026

The gas pump is not a parking spot. Vacate if you are not actively paying or pumping

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Michael Guertin @guertin.bsky.social · 06/06/2026

Maybe we stop drinking in our 40s because 2 beers is not enough for a buzz, but sufficient for a hang over.

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Michael Guertin @guertin.bsky.social · 05/06/2026

AI slop and electric scooters/mopeds make society worse.

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Michael Guertin @guertin.bsky.social · 15/05/2026

If you are an admin and claim something is policy and not just your convention, you should be able to point to a written policy. Everyone's priority at the university is to support the education and research missions! do not make our lives harder for no reason.

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Michael Guertin @guertin.bsky.social · 06/05/2026

i often hear faculty complaining that students do not enter graduate school with the skills necessary to complete a PhD. they don't seem to understand that graduate students need to be trained in these skills.

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Michael Guertin @guertin.bsky.social · 05/05/2026

in the era where moving small amounts of liquid between tubes and bioinformatics is relatively easy, domain expertise and knowing how to address a question is what will get you a fellowship, grant, job, tenure, etc

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Michael Guertin @guertin.bsky.social · 10/04/2026

I am glad I went to college without a cell phone and without AI

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Michael Guertin @guertin.bsky.social · 07/04/2026

conflating statistical significance and biological significance is the downfall of many scientists. We have really sensitive assays in 'omics, so be careful about chasing small effect sizes of statistically significant phenomenon.

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Michael Guertin @guertin.bsky.social · 01/04/2026

I would much rather complete a ChIP-seq analysis midterm than grade 16 midterms. Giving everyone their own transcription factor raw data makes it much tougher to grade.

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Michael Guertin @guertin.bsky.social · 25/03/2026

does phenol:chloroform still dissolve serological pipettes? is this still a concern that my students shoudl have?

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Michael Guertin @guertin.bsky.social · 25/03/2026

digitally signing documents with Adobe is the hardest part of my job. Signatures always disappear, nothing seems reproducible. I can see signatures in Preview, but not Acrobat; I see them on email previews, but not when it is downloaded. I must be missing something. Is it because I am 40+ now?

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Reposted by Michael Guertin

All-Ireland Chromatin Consortium @aicc-ireland.bsky.social · 10/03/2026

⏰ Calling all chromatin aficionados! We we will be joined by @adelmanlab.bsky.social from @harvardmed.bsky.social for our March 27th webinar 📅 Karen will be sharing her groups work on 'Transcription & RNA Quality Control in Health & Disease' 😷🧬 Register here: us06web.zoom.us/webinar/regi...

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Seychelle Vos @voslab.org · 12/02/2026

Please join Andreas Ladurner and me for the GRC Chromatin Structure and Function conference to be held near Barcelona Spain from May 31-June 5! We accepting abstracts for posters and talks. The meeting is preceded by an awesome GRS. Learn more in our video below and apply www.grc.org/chromatin-st...

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Michael Guertin @guertin.bsky.social · 11/02/2026

consistently having smaller incoming PhD class sizes is going to kill labs. I am fortunate to have grants, but with incoming PhD classes at 15 for the entire UConn Health, there is no way I can fill out the 3 student positions I can fund.

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Michael Guertin @guertin.bsky.social · 02/02/2026

when my university communications office wants to highlight/detract from the data, they selectively include zero on the y-axis or not. They also seem to really like default excel graphics

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Michael Guertin @guertin.bsky.social · 30/01/2026

If I fill out a scheduling poll, it is not safe to assume that I will still be free at those same times over 2 weeks later.

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Michael Guertin @guertin.bsky.social · 23/01/2026

you paper was in review for 4 months, then one month of editorial who knows what. YOU HAVE 24 MINUTES TO GET THESE PROOFS BACK TO US!!!!

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Michael Guertin @guertin.bsky.social · 21/01/2026

Is it ok to use "you nerds" as a gender neutral term to refer to the students in class? I cannot get myself to use "y'all" and "you guys" is not neutral.

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Michael Guertin @guertin.bsky.social · 15/01/2026

submitting to a journal who accepts LaTeX submission, but the .bst file is not correct and they cannot send me a correct one. Why bother having editors, copy editors, and production staff?

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Michael Guertin @guertin.bsky.social · 14/01/2026

my 13 year old is learning to code and I told him he should not use chatGPT. I know he listened because the code is crap (but it works!) and all his comments are just commented out print() statements.

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Reposted by Michael Guertin

Teif lab @teiflab.bsky.social · 29/12/2025

As usual this time of year, started drafting the list of gene regulation conferences for 2026, enjoy! generegulation.org/conferences-... Know of a relevant event that’s missing? Please reply below

generegulation.org

Conferences & Schools – 2026 – Gene Regulation – Teif Lab

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Michael Guertin @guertin.bsky.social · 05/01/2026

the solution for a leaky roof at UVA and UConn Health seems to be a bucket under the leak. This should be embarrassing and they should use indirects to fix the problem.

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Reposted by Michael Guertin

Alex Stark @alex-stark.bsky.social · 29/12/2025

Join @stirlingchurchman.bsky.social, @moffittlab.bsky.social, @saramostafavi.bsky.social, me and all speakers for the 2026 CSHL meeting Systems Biology: Global Regulation of Gene Expression, March 11-14. Abstract deadline January 9! More infos and registration at meetings.cshl.edu/meetings.asp...

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Michael Guertin @guertin.bsky.social · 12/12/2025

I usually see "peaked" as opposed to "piqued" __my interest__ in graduate school applications, but I got "peeked" for the first time this cycle!

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Michael Guertin @guertin.bsky.social · 17/11/2025

Does anyone have a -80 that they like? Ideally one that doesn't require a thaw every year and constant software updates. I really want one from 1990.

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Michael Guertin @guertin.bsky.social · 27/10/2025

we should force politicians to take 9th grade math tests or critical reasoning tests live during a debate. speaking words confidently is not a great measure of competency.

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Michael Guertin @guertin.bsky.social · 24/10/2025

anyone applying for jobs, PhD slots, or really anything: it is easy to tell if chatGPT spouted out some vague and general essay that recycles language from the advertisement, compared to a sincere narrative informed by personal experiences.

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Michael Guertin @guertin.bsky.social · 23/10/2025

your -80 stopped working because you did not update the software is so stupid. I don't know if it is true, but this should not be possible. I want a -80 from 1986

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Michael Guertin @guertin.bsky.social · 21/10/2025

is everyone else having issues logging into the NIH eRA commons?

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Michael Guertin @guertin.bsky.social · 15/10/2025

we are recruiting a postdoc with interest in using genomics and molecular biology to study transcription factors. We have an R35 to fund the project/salary.

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Michael Guertin @guertin.bsky.social · 03/10/2025

I don't understand why a wheel speed sensor is $20 online and $200 at any auto parts store. I don't find this to be the case for most parts

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Michael Guertin @guertin.bsky.social · 24/09/2025

are double em dashes common with chatGPT write ups? I don't recall seeing them often until recently.

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Reposted by Michael Guertin

Zeitlinger Lab @zeitlingerlab.bsky.social · 19/09/2025

Excited to join Bluesky! Looking forward to seeing the cool research everyone posts!

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Reposted by Michael Guertin

Craig Kaplan @triggerloop.bsky.social · 16/09/2025

Here are the proposed dates

Screenshot of estimated post date for NIH MIRA R35 research grant program for established investigators (11/3/2025) with applications anticipated as due 1/27/2026

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Michael Guertin @guertin.bsky.social · 12/09/2025

Not replying to emails and being late on everything is apparently considered quirky and charming amongst colleagues. Faculty should not laugh this behavior off, normalize it, and enable. Being inconsiderate adds work for everyone else. Pointing out the behavior shouldn’t make me the jerk.

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Michael Guertin @guertin.bsky.social · 09/09/2025

in your 40s, it is necessary to stretch before taking the trash bin down the driveway or you'll hurt your back.

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Michael Guertin @guertin.bsky.social · 09/09/2025

Am I missing something or is there still no Program Announcement for R35s at NIGMS that are not ESI?

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Reposted by Michael Guertin

Cheryl Keller @cherylkeller.bsky.social · 22/08/2025

Excited to announce that I’ll be the Director of the Huck Institutes of the Life Sciences Genomics Core Facility starting mid September 🧬🧪🧫 www.psu.edu/news/huck-in...

psu.edu

New director appointed at Huck Institutes Genomics Core | Penn State University

Research Professor Cheryl Keller has been named the new director of the Genomics Core Facility in the Huck Institutes of the Life Sciences.

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Michael Guertin @guertin.bsky.social · 22/07/2025

I don't mind drinking Drosophila that meet their end in my glass of wine.

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Michael Guertin @guertin.bsky.social · 18/07/2025

perspective: Human geneticists will soon have to figure out how the genes/encoded proteins lead to the phenotype. More GWAS variants with smaller effect sizes and more molecular phenotyping (QTL) is not sustainable. who cares about the causal variant? Figure out what the causal gene/protein does!

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Reposted by Michael Guertin

Genes & Development @genesdev.bsky.social · 10/07/2025

In this study, Mimoso et al. show that Restrictor serves as a transcriptional safeguard that suppresses the spurious transcription of non-coding RNAs, while preserving mRNA transcription. Learn more here: ➡️ tinyurl.com/gd352654

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Reposted by Michael Guertin

Biochemical Society @biochemsoc.bsky.social · 26/06/2025

Taking place on 17-19 September 2025, Transcription and Chromatin UK will showcase cutting-edge research and is a ‘mustattend’ for anyone within the transcription and epigenetics community🧪. Register now: www.eventsforce.net/biochemsoc/2...

Transcription and Chromatin UK
Manchester, UK
17-19 September 2025
Earlybird deadline: 17 July 2025

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