Neural crest cells differentiate into skeletogenic mesenchyme and neuro-glial lineages, thereby contributing to craniofacial formation. Here, single-cell analysis of cranial neural crest shows that sp...

Summary: This Editorial offers an honest look at impact factor trends in developmental biology, explains how Development serves its community, and makes the case that sustaining developmental biology ...

Problem-solving using novel solutions without explicit training is often considered a hallmark of cognitive flexibility. We investigated whether bumble bees (Bombus terrestris) could solve a novel obj...

In this Comment, Cedric Feschotte highlights evidence from diverse lineages showing that transposable elements are key drivers of evolutionary innovation, repeatedly introducing regulatory and coding ...

Frenster et al. utilize mosaic mouse gastruloids as a model of cell fitness and competition, identifying a temporal window between primed pluripotency and early gastrulation during which cell competit...

UCL is consistently ranked as one of the top ten universities in the world (QS World University Rankings 2010-2022) and is No.2 in the UK for research power (Research Excellence Framework 2021).

Following an open letter of 1 February, Sir Ian Chapman responds to feedback and provides an update.

Chromatin organization, through the assembly of DNA with histones and the folding of nucleosome chains, regulates DNA accessibility for transcription, DNA replication and repair. Although models deriv...

How did eukaryotic cells with complex architecture evolve from simpler prokaryotic cells? DNA analyses offer possible answers.

UKRI Chief Executive outlines changes to UKRI investment approach, addressing concerns about research funding and the financial position of STFC.

UKRI Chief Executive outlines changes to UKRI investment approach, addressing concerns about research funding and the financial position of STFC.

Objective peer review, and HHS- and NIH- specific priorities, and a standardized, transparent process for incorporating NIAID-specific priorities will guide funding selections.

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YouTube video by Bruce Springsteen

Nature Communications - The type I interferon response is suppressed during early development, making embryos susceptible to pathogens. Here, the authors show that this suppression contributes to...

Dorota Skowronska-Krawczyk sits in her office, eyes fixed on the computer monitor in front of her. "You see it move its eye," says the UC Irvine associate professor of physiology and biophysics, point...

Highlighted Article: SALL4A recruits BAF to activate neural crest enhancers early in development, revealing why SALL4 mutations cause craniofacial anomalies in human congenital syndromes.

Highlighted Article: SALL4A recruits BAF to activate neural crest enhancers early in development, revealing why SALL4 mutations cause craniofacial anomalies in human congenital syndromes.

This Resource provides a detailed atlas of morphogen-induced responses in human neural organoids.

A new type of mRNA splicing mechanism discovered in Caenorhabditis elegans that detects and removes inverted repeats also occurs in human cells, thereby providing another strategy to protect against t...

Nature Communications - Reversibility, regulation, and the community of development: the legacy of Sir John B. Gurdon

Inge et al. show that human endoderm originates from two converging developmental routes with distinct dynamics and efficiencies yet similar developmental potential. Combinatorial activin and BMP4 sig...

Intragenomic conflict with selfish genetic elements spurs adaptive changes in subunits of essential multiprotein complexes. Whether and how these adaptive changes disrupt interactions within such comp...