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Katherine Aird

@airdlab.bsky.social
2.6K followers 1.4K following 94 posts

My lab studies the interplay between cancer metabolism and cell cycle dysregulation. Professor at The Wistar Institute airdlab.com

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Katherine Aird @airdlab.bsky.social · 30/07/2026
Thrilled to see our work on senescence & metastasis out! We found that chemotherapy increases ovarian cancer metastasis in a paracrine manner via fructose. Dietary fructose is sufficient to increase metastatis. This work has multiple implications related to both chemo and diet.
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Barbara Marte @barbmarte.bsky.social · 28/05/2026
new out in Nature www.nature.com/articles/s41...
nature.com
αKG-mediated carnitine synthesis drives DNA repair via histone acetylation - Nature
The metabolite αKG promotes carnitine synthesis and increases site-specific histone acetylation, thereby promoting homologous recombination-mediated DNA repair, which has potential implications f...
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Andrea Andress Huacachino, PhD @chemistandrea.bsky.social · 27/05/2026
Amazing work from @airdlab.bsky.social and @mzspectrum.bsky.social Labs led by insanely talented Apporva Uboveja! Very grateful to play a small part in this impactful work.
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Katherine Aird @airdlab.bsky.social · 27/05/2026
It's time to rewrite reviews-aKG doesn't just regulate demethylation. Work from my lab and @mzspectrum.bsky.social demonstrates a new role for aKG in promoting histone acetylation and DNA repair through regulating carnitine synthesis. Congrats Apoorva Uboveja! www.nature.com/articles/s41...
nature.com
αKG-mediated carnitine synthesis drives DNA repair via histone acetylation - Nature
The metabolite αKG promotes carnitine synthesis and increases site-specific histone acetylation, thereby promoting homologous recombination-mediated DNA repair, which has potential implications f...
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Katherine Aird @airdlab.bsky.social · 02/05/2026
The lab is expanding and hiring both a postdoc and staff scientist! See more on our website: airdlab.com. We study how metabolism and cell cycle states drive tumor progression, therapy response, and immune interactions. Candidates interested in mechanistic cancer biology are encouraged to apply.
airdlab.com
Aird Lab
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Katherine Aird @airdlab.bsky.social · 11/04/2026
Looking for a postdoc position and attending AACR in San Diego? I'll be there, too, and the lab is actively recruiting! Send me an email with your CV and cover letter, and I’ll follow up if there is a mutual fit. See more about our research at airdlab.com.
airdlab.com
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Rich Possemato @richpossemato.bsky.social · 09/01/2026
Join us for the 2026 NYAS Cancer Metabolism conference on March 24th at NYU Langone! The poster deadline is rapidly approaching. Speakers include @airdlab.bsky.social @bensahralab.bsky.social Javier Garcia-Bermudez, Marcus Goncalves, @naama-kanarek.bsky.social @bdmanning.bsky.social Erika Pearce,
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Ronny Drapkin @rdrapkin8-penn.bsky.social · 22/09/2025
Excited to share the Ovarian Cancer Research Syndicate line-up of speakers for the fall. Please share. We have amazing trainees presenting and the latest from leaders in the field. @powelldrescher.bsky.social @srocf.bsky.social @pennmedcso.bsky.social @penncancer.bsky.social
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Katherine Aird @airdlab.bsky.social · 18/09/2025
My lab at The Wistar Institute is recruiting on multiple levels! We are looking for a research technician and/or senior lab manager to help support all lab projects. Cell culture, molecular biology, and animal handling expertise and 3+ years of experience needed. Apply here: lnkd.in/ecvdTwkf
lnkd.in
Job Details | Dayforce Jobs
Find your next adventure
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Katherine Aird @airdlab.bsky.social · 03/09/2025
Big day for multiple lab members who celebrated a promotion! Congrats to Apoorva Uboveja for promotion to Staff Scientist and Aidan Cole for starting as a postdoc! I am now a full professor too 🤓 Want to learn more about our science or join the lab? Visit Airdlab.com
airdlab.com
Aird Lab
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Katherine Aird @airdlab.bsky.social · 14/08/2025
The summer has been busy! Along with the move and a PhD defense, we have updated two preprints: www.biorxiv.org/content/10.1... www.biorxiv.org/content/10.1...
biorxiv.org
The chemotherapy-induced senescence-associated secretome promotes cell detachment and metastatic dissemination through metabolic reprogramming
Cellular senescence, characterized by a stable cell cycle arrest, is a well-documented consequence of several widely used chemotherapeutics that has context-dependent roles in cancer. Although senesce...
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Katherine Aird @airdlab.bsky.social · 22/07/2025
I could not be more excited to finally announce that my lab will be moving to The Wistar Institute in Philadelphia in early September! While this is somewhat of a homecoming for me, it is a new adventure for the 6 lab members moving with me! More details to come about new roles and opportunities!
jobs.dayforcehcm.com
Job Details | Dayforce Jobs
Find your next adventure
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Katherine Aird @airdlab.bsky.social · 23/04/2025
Our preprint by @raquelbuj.bsky.social was highlighted! What a cool idea to give early career scientists the opportunity to practice peer review skills! See the updated preprint: www.biorxiv.org/content/10.1....
biorxiv.org
CDKN2ALow cancer cells outcompete macrophages for microenvironmental zinc to drive immunotherapy resistance
Approximately 50% of cancers exhibit decreased CDKN2A expression ( CDKN2A Low), which is linked to immune checkpoint blockade (ICB) resistance. While CDKN2A is traditionally recognized as a tumor supp...
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Katherine Aird @airdlab.bsky.social · 14/03/2025
Anyone else having trouble contacting Fetterman? I’ve tried both his DC and Pittsburgh office numbers, and it keeps disconnecting
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Jeremy Berg @jeremymberg.bsky.social · 13/02/2025
Bluetorial: The rationale for the “NIH” indirect cost “plan” is based on misunderstood (unintentional or intentional) accounting and math The value of real government transparency
media.tenor.com
a cartoon of homer simpson holding a card
ALT: a cartoon of homer simpson holding a card
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Katherine Aird @airdlab.bsky.social · 12/02/2025
If you are worried about the constitutional crisis, NIH/NSF funding, diversity issues, or anything else: CONTACT YOUR REPRESENTATIVES. For those in PA: Dave McCormick: 202 224 6324 (www.mccormick.senate.gov/share-your-o...) John Fetterman: 202 224 4254 (www.fetterman.senate.gov/contact/)
summerlee.house.gov
Contact - Summer Lee
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Josh Gerstein @joshgerstein.bsky.social · 11/02/2025
BREAKING: Federal judge in Boston broadens block on Trump's NIH grant 15% overhead limit (indirect cost rates) to all recipients nationwide. Doc: www.documentcloud.org/documents/25... #TROpalooza ain't done
documentcloud.org
AAMCOrd021025
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Jeremy Berg @jeremymberg.bsky.social · 10/02/2025
A useful tool and a great thing to do... 5calls.org/issue/nih-ns...
5calls.org
Save NIH and NSF Research Funding ⭑ 5 Calls
On February 7, the Trump administration moved to cut billions of dollars in funding from the National Institutes of Health (NIH) and National Science …
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Stephen Floor @snf.bsky.social · 09/02/2025
not paying indirect costs for research is like only paying the players in the Super Bowl. can't have a Super Bowl without coaches, referees, security, janitors, announcers, stadium staff, and a stadium - and you can't have research without supporting people and facilities
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Katherine Aird @airdlab.bsky.social · 09/02/2025
Cutting NIH funds hurts all Americans. Why? Three main reasons: #1: These funds support a huge industry in all states. For every $1 of NIH funding generated, there is a short-term return of ~$2.46 in economic activity. $4B in cuts will take away $10B from the economy.
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Katherine Aird @airdlab.bsky.social · 13/12/2024
So proud of Richard Fang, a senior undergrad in the lab, highlighted in this nice write-up. He is about to graduate and move on to bigger and better things as an MD/PhD student, and we will miss him! www.pitt.edu/pittwire/fea...
pitt.edu
This Pitt senior and cancer researcher is one to keep watching
Here’s what’s next for Richard Su Fang, a Goldwater scholar who has already received interview invitations from 17 MD/PhD programs.
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Christian Frezza @frezzalab.bsky.social · 08/12/2024
Good Sunday. This weekly summary of papers in #cancermetabolism and #mitochondrialbiology is full of exciting discoveries. Check it here: biomed.news/bims-camemi/... @biomednews.bsky.social "The greatest obstacle to living is expectancy, which hangs upon tomorrow and loses today."-Seneca
media.tenor.com
a poster that says " never stop reading " next to a magazine
ALT: a poster that says " never stop reading " next to a magazine
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TheRaiLab @therailab.bsky.social · 03/12/2024
This project started with a talented grad student noticing that low levels of sGC correspond to the ability of CSPC cells to evade androgen deprivation-induced senescence. Six years (2 in peer review) and one pandemic later, voila… aacrjournals.org/cancerres/ar...
aacrjournals.org
Stimulating Soluble Guanylyl Cyclase with the Clinical Agonist Riociguat Restrains the Development and Progression of Castration-Resistant Prostate Cancer
Abstract. Castration-resistant prostate cancer (CRPC) is incurable and fatal, making prostate cancer the second-leading cancer-related cause of death for American men. CRPC results from therapeutic re...
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Science News @scinews.bsky.social · 04/12/2024
Academic Journals and News (Updated Dec 3, 2024) go.bsky.app/hCfhqn
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Christian Frezza @frezzalab.bsky.social · 04/12/2024
As the community grows fast, here is an updated Metabolism Starter Pack 2 with loads of exciting scientists go.bsky.app/CH1MctZ
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Katherine Aird @airdlab.bsky.social · 04/12/2024
Want a cliffsnote version of amazing cancer discoveries from 2024? Check out the Dec issue of Cancer Discovery. It was hard to pick just 1 paper to highlight!
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Females in Mass Spectrometry (FeMS+) @femalesinms.bsky.social · 30/11/2024
Hi #TeamMassSpec! #FeMS+ has joined BlueSky! Please share and get the word out so we can build up a base here.
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Katherine Aird @airdlab.bsky.social · 01/12/2024
Do you want to read about what it’s like to be a mid- or senior career female scientist? Read this. The sexism and misogyny absolutely gets worse the higher you go.
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Christian Frezza @frezzalab.bsky.social · 01/12/2024
Goood Sunday, all! A very exciting curated issue of papers in #cancermetabolism and #mitochondrialbiology is waiting for you here: biomed.news/bims-camemi/... @biomednews.bsky.social #readingtime "Most human beings have an almost infinite capacity for taking things for granted."-Aldous Huxley
media.tenor.com
a drawing of a man with glasses and gloves with the words science mode written above him
ALT: a drawing of a man with glasses and gloves with the words science mode written above him
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Christian Frezza @frezzalab.bsky.social · 01/12/2024
Dietary Restriction Enhances CD8⁺ T Cell Ketolysis to Limit Exhaustion and Boost Anti-Tumor Immunity 🧪 www.biorxiv.org/content/10.1...
biorxiv.org
Dietary Restriction Enhances CD8⁺ T Cell Ketolysis to Limit Exhaustion and Boost Anti-Tumor Immunity
Reducing calorie intake without malnutrition limits tumor progression but the underlying mechanisms are poorly understood. Here we show that dietary restriction (DR) suppresses tumor growth by enhanci...
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Katherine Aird @airdlab.bsky.social · 28/11/2024
It’s my lab’s 8th birthday today. I am overwhelmed with gratitude to be able to do this job, mentor my trainees (currently killing it 🤩), and interact with the smartest colleagues and collaborators one could ask for. Mid-career hasn’t been easy, and I’m thankful to still be making cool discoveries.
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Christian Frezza @frezzalab.bsky.social · 24/11/2024
Good morning all! Another week of fantastic papers in #cancermetabolism and #mitochondrialbiology has just passed. Don't miss these papers, find them here: biomed.news/bims-camemi/... @biomednews.bsky.social "Calm down. Both your sins and your good deeds will be lost in oblivion." -Czesław Miłosz
media.tenor.com
a cartoon of a robot reading a newspaper with the words morning news below him
ALT: a cartoon of a robot reading a newspaper with the words morning news below him
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Stylianos Lefkopoulos (he/him) @slefkopoulos.bsky.social · 20/11/2024
Are you ready for this? We are on Bluesky too!!! Follow the account of NATURE CELL BIOLOGY below! bsky.app/profile/natu...
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TheRaiLab @therailab.bsky.social · 20/11/2024
Our NCI-funded SURF program applications are open! Pls share w any rising juniors or seniors who want to spend 10 weeks next summer doing research with our med school faculty and living on our beautiful Coral Gables campus. More info and app link here: med.miami.edu/graduate-stu...
med.miami.edu
Summer Undergraduate Research Fellowship (SURF)
Official website for the University of Miami Leonard M. Miller School of Medicine
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Christian Frezza @frezzalab.bsky.social · 19/11/2024
Metabolism starter pack now full with 150 contacts! go.bsky.app/VavECSX
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Christian Frezza @frezzalab.bsky.social · 19/11/2024
I am very excited to share this preprint led by Cissy Yong. 🧪 This study shows how tumour sampling conditions during surgery can alter the metabolic profile of ccRCC tissues, with major research implications #Metabolomics (now with the correct link) www.researchsquare.com/article/rs-5...
researchsquare.com
Tumour sampling conditions perturb the metabolic landscape of clear cell renal cell carcinoma
Human isotopic tracer studies are fast becoming the gold standard model to study cancer metabolism in vivo. Analysed tissues are typically retrieved after surgical resection, which exposes them to a v...
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Adrian Saurin @adesaurin.bsky.social · 17/11/2024
A list of people interested in cell cycle entry and exit. Reply to this post if you want to be added. #senescence #cellcycle go.bsky.app/7hEivbt
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Johanna Joyce @johannajoyce.bsky.social · 17/11/2024
Here's the #Cancer #Research #2 starter pack 🤩 Researchers, oncologists, patient advocates & more -working across all aspects of cancer research and treatment 🧪🔬⚕️ I also tried to give some exposure to #PhD #students & #postdocs - randomly picked from followers of me or my lab! go.bsky.app/6EcjWNA
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Christian Frezza @frezzalab.bsky.social · 18/11/2024
Let's start the week at Bluesky with an updated Starter Pack V3.0 #metabolism and #mitochondrialbiology are super strong here! go.bsky.app/VavECSX
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Denis Wirtz @deniswirtz.bsky.social · 17/11/2024
Download our database of 492 (!) funding opportunities for EARLY-CAREER FACULTY AND RESEARCHERS. For each entry, we provide link to funder, description, amount, deadline, and eligibility criteria (e.g. citizenship). Download freely here: research.jhu.edu/rdt/funding-...
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Katherine Aird @airdlab.bsky.social · 17/11/2024
Hello to so many new followers! We recently received fundable scores on 2 R01s and are actively recruiting multiple postdocs. The broad theme of the lab is cancer cell metabolism, and I tailor projects to the postdoc’s scientific interests and career goals. See more: Airdlab.com
airdlab.com
Aird Lab
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Christian Frezza @frezzalab.bsky.social · 15/11/2024
Updated extensive starter pack for #cancermetabolism and #mitochondrialbiology go.bsky.app/VavECSX
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Oded Rechavi @odedrechavi.bsky.social · 12/11/2024
For a PhD student, choosing a good lab is 10 times more important than choosing a particular topic to study
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Richard Sever @richardsever.bsky.social · 10/11/2024
Reminder for newcomers that bioRxiv has Bluesky accounts in every subject category - great way to keep up (please re-skeet) connect.biorxiv.org/news/2023/09...
connect.biorxiv.org
bioRxiv expands on Mastodon and Bluesky
bioRxiv - the preprint server for biology, operated by Cold Spring Harbor Laboratory, a research and educational institution
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Tim Rhoads @timwrhoads.bsky.social · 08/11/2024
Trying to find all the metabolism/mito folks on here, so i created a starter pack. Please suggest anyone I missed! go.bsky.app/C2t7snh
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Piotr Jung-Sillah @jung-sillah.bsky.social · 09/11/2024
go.bsky.app/7xTwrrn
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Anne-Ruxandra Carvunis @carvunis.bsky.social · 10/11/2024
Hi, are there some starter packs for molecular evolution, or evolutionary biology in general?
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Katherine Aird @airdlab.bsky.social · 10/11/2024
Excited to see so many scientists active here over the past few days! As a re-introduction, I am a faculty member at UPitt, and my lab focuses on cancer metabolism and its intersection with cell cycle dysregulation. We are actively recruiting postdocs!! See more at Airdlab.com
airdlab.com
Aird Lab
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Katherine Aird @airdlab.bsky.social · 09/11/2024
One of the best things for me about that other site was finding good papers to read. Where are all the journals? Have they not migrated here?
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Katherine Aird @airdlab.bsky.social · 09/11/2024
Switching back to Bluesky after the shit show of this week! Hi everyone! 👋
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