Reposted by Gonca Erdemci-Tandogan
Really excited to finally show off our work on the specification of neuroblasts. While it has been a long-standing model for lateral inhibition, we show that Notch does not select the NB, but instead reinforces fate decisions.
www.cell.com/current-biol...
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cell.com
Positional cues, not Notch, direct neuroblast selection during early neurogenesis in the Drosophila embryo
Using quantitative live imaging, Green et al. show that proneural gene expression
is biased by positional cues and that Notch is activated only after neuroblast selection
in the Drosophila embryo. Thi...