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Anchel de Jaime-Soguero

@ancheldjs.bsky.social
243 followers 406 following 30 posts

Cell and developmental biology enthusiast studying cellular communication. Group leader at IRIBHM-ULB, Belgium

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Anchel de Jaime-Soguero @ancheldjs.bsky.social · 22/09/2026
Great contribution @fueyoraquel.bsky.social , congratulations to you and your lab members! If you would like to share novel stem cell–based models or state-of-the-art technologies and their applications, please have a look at the collection. www.jove.com/topical-coll...
jove.com
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Development @dev-journal.bsky.social · 15/09/2026
In preprints – the embryo, the placenta and lessons from developmental metabolism @bernasozen.bsky.social explores how recent #preprints by Aguilera-Castrejon et al. & Xu et al. reveal metabolic roles for embryonic and extra-embryonic tissues during mid-gestation. doi.org/10.1242/dev....
doi.org
In preprints – the embryo, the placenta and lessons from developmental metabolism
This article discusses the preprinted work of Lokshtanov and colleagues (Lokshtanov et al., 2026 preprint) as well as that of Xu and team (Xu et al., 2026 preprint). As preprints, these works have…
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Development @dev-journal.bsky.social · 11/09/2026
Meet our Preprint Editors We are pleased to welcome Anchel de Jaime-Soguero @ancheldjs.bsky.social from @iribhm.bsky.social to our first group of Preprint Editors to our editorial team, responsible for handling our 'In preprints' articles. journals.biologists.com/dev/pages/pr...
Profile card for Anchel de Jaime-Soguero, Preprint Editor (Development) at IRIBHM Jacques E. Dumont Institute, Belgium. The card includes a quote about contributing to a more critical and insightful preprint landscape, increasing visibility for authors, and refining research judgment. Key topics listed are early embryogenesis, signalling, and stem cells. On the right, a portrait photo shows Anchel in a laboratory.
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Development @dev-journal.bsky.social · 11/08/2026
In preprints – can a signaling snapshot reveal the fate of a cell? @ancheldjs.bsky.social highlights a #preprint by Fijabi, @heemskerklab.bsky.social & co that offers a new way of thinking about how cells translate extracellular information into developmental outcomes. doi.org/10.1242/dev....
doi.org
In preprints – can a signaling snapshot reveal the fate of a cell?
During development, cells are exposed to multiple types of signals that often overlap and instruct them when to divide, migrate or differentiate (Row et al., 2018; Pera et al., 2003; Derynck et al.,…
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Anchel de Jaime-Soguero @ancheldjs.bsky.social · 04/08/2026
Our lab has just launched a new website! 🎉🧫 Take a look at our research projects and meet the people behind the science at the Developmental Resilience Lab, based at @iribhm.bsky.social @ulbruxelles.bsky.social . dejaimesoguero-lab.ulb.be
dejaimesoguero-lab.ulb.be
De Jaime – Soguero Lab
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David Brückner @davidbrueckner.bsky.social · 25/07/2026
Our paper about predicting cell fates from combinatorial signals in 2D human gastruloids received a preprint highlight in @dev-journal.bsky.social Thank you @ancheldjs.bsky.social for a great perspective piece on our work! 👉 journals.biologists.com/dev/article/...
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Anchel de Jaime-Soguero @ancheldjs.bsky.social · 01/06/2026
Interested in stem cell-based models of early mammalian development? Our JoVE Methods Collection is actively seeking exciting new contributions. If you have a novel method, protocol, or perspective, we'd love to hear from you—reach out and submit an abstract! www.jove.com/methods-coll...
jove.com
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Development @dev-journal.bsky.social · 01/05/2026
Meet our Preprint Editors We are pleased to welcome our first group of Preprint Editors to our editorial team, responsible for handling our 'In preprints' articles. #preprints journals.biologists.com/dev/pages/ed...
Clarisse Brunet Avalos, Anchel de Jaime-Soguero, Joaquina Delas, Gwendolyn K. Kirschner, Daniel Ríos-Barrera, Sumeet Pal Singh, Roshana Thambyrajah and Xianfa Yang.
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Anchel de Jaime-Soguero @ancheldjs.bsky.social · 12/05/2026
Excited to be part of the first cohort of Preprint Editors at @dev-journal.bsky.social @biologists.bsky.social I will discuss selected preprints in stem cell biology, embryogenesis, signaling & genome integrity. Contact me if you come across an interesting preprint that you wish to highlight!
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Anchel de Jaime-Soguero @ancheldjs.bsky.social · 25/03/2026
New hypothesis paper: the anterior–posterior (A–P) axis in early embryos may do more than pattern the body—it could create gradients of genome stability, with anterior regions more error-prone and posterior regions protected by morphogen signaling. 🧬 onlinelibrary.wiley.com/doi/10.1002/...
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Anchel de Jaime-Soguero @ancheldjs.bsky.social · 29/01/2026
🚨 PhD opportunity Interested in stem cells, mammalian development, and omics? The Migeotte & De Jaime-Soguero labs are recruiting a PhD student with bioinformatics background to work on embryonic and extraembryonic development. 🗓 Deadline April 2026 👇 Details below www.iribhm.org/open-positio...
iribhm.org
PhD Position — IRIBHM Jacques E. Dumont
Anchel De Jaime Soguero Lab: PhD position in cellular and developmental biology
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Wittamer Lab @valeriewittamer.bsky.social · 13/12/2025
🚨 Paper alert! The final version of our latest manuscript is published. We are excited to share this new resource for the zebrafish community and beyond: doi.org/10.7554/eLif... Congratulations to all authors! 🥳
doi.org
A single-cell transcriptomic atlas reveals resident dendritic-like cells in the zebrafish brain parenchyma
The zebrafish brain combines a conserved heterogeneity of immune cells with a unique dendritic cell-like population.
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Alfonso Martinez Arias @amartinezarias.bsky.social · 23/12/2025
Beautiful, thorough, personal in places, memoir of John Gurdon from Eddy de Robertis, disciple and friend. Å #MustRead about a generation and a time from which we have moved on but that laid the foundation for contemporary biology. www.sciencedirect.com/science/arti...
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Anchel de Jaime-Soguero @ancheldjs.bsky.social · 20/12/2025
Cellular signaling (BMP/SMAD) at the helm of chromosomal instability in cancer, similar as what we described during development and lineage specification. Congrats to our collaborators at the Bastians lab.
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Anchel de Jaime-Soguero @ancheldjs.bsky.social · 16/07/2025
‼️‼️📢📢 Job Alert! Our lab at @iribhm.bsky.social - @ulbruxelles.bsky.social is seeking for a PhD student to work on the proteostasis of early mammalian development using stem cell models and the embryo. If you are enthusiastic about cell and dev biology, please apply!
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Anchel de Jaime-Soguero @ancheldjs.bsky.social · 02/07/2025
Excited to present our work tomorrow online at Social DNAing series. 18.00PM CEST time following the link below.
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Alfonso Martinez Arias @amartinezarias.bsky.social · 23/06/2025
The modularity of the mammalian #embryo in display. Controlled assembly of classic #gastruloids and uncommitted precursors in #hypoxia, patterns the AP axis www.biorxiv.org/content/10.1... Beautiful & insightful from @bulutkarslioglu.bsky.social‬ group. Building models to learn and learning.
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The Francis Crick Institute @crick.ac.uk · 15/05/2025
Crick researchers have developed a new stem cell model of the mature amniotic sac development. The team is now exploring the potential for using these new 3D models in clinical applications, such as cornea reconstruction and treating ulcers. www.crick.ac.uk/news/2025-05...
crick.ac.uk
New stem cell model sheds light on human amniotic sac development
Researchers at the Francis Crick Institute have developed a new stem cell model of the mature human amniotic sac, which replicates development of the tissues supporting the embryo from two to four wee...
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Virtual Gastrulation Zoom Talks @vgzt2021.bsky.social · 07/05/2025
Join us tomorrow for our next seminar: 🗓️ Thursday, May 08 ⏰ 9:30 PDT / 12:30 EDT / 16:30 UTC / 17:30 BST / 18:30 CET
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Anchel de Jaime-Soguero @ancheldjs.bsky.social · 02/05/2025
Looking forward to giving this talk next week!
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Rajiv McCoy @rajivmccoy.bsky.social · 07/04/2025
Aneuploidy is the leading cause of pregnancy loss. In work led by @saracarioscia.bsky.social and @aabiddanda.bsky.social, we reanalyzed genetic testing data from 139,416 IVF embryos to discover variants associated with recombination phenotypes and aneuploidy risk. www.medrxiv.org/content/10.1...
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Anchel de Jaime-Soguero @ancheldjs.bsky.social · 30/03/2025
Last few months have been of change. I finished my postdoc at @cosheidelberg.bsky.social and moved to Belgium to begin my research group at @iribhm.bsky.social. I will reflect here my thoughts about the last years experience.
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Development @dev-journal.bsky.social · 17/03/2025
In this Review, @eliananehme.bsky.social, @amiteshp.bsky.social, Isabelle Migeotte and @pasquelab.bsky.social give an overview of the embryonic origin and function of extra-embryonic mesoderm in vertebrates from in vivo studies. journals.biologists.com/dev/article/...
Figure 1 Schematics of extra-embryonic mesoderm development across species. (A) An intermediate stage of reptilian development displaying the vascularized trilaminar omphalopleure, also known as choriovitelline membrane, and the bilaminar omphalopleure. (B) A later developmental stage in squamates, showing a feature unique to squamates: the yolk cleft. The composition of the amnion, allantois and chorion is similar in all reptiles. (C) E1 (24 h) chick embryo showing the primitive streak, area vitellina and vasculosa. (D) E10 chick embryo displaying the localization of vascularized and non-vascularized extra-embryonic mesoderm (EXM) cells.
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Acebrón @acebronsp.bsky.social · 26/02/2025
Do you want to illuminate your studies on innate immune responses? Our new biosensor monitors mtDNA from apoptosis, viral infections, other sources of dsDNA and environmental cGAMP. We also show that micro nuclei are poor activators of the #STING response
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Anja Groth @groth-anja.bsky.social · 26/02/2025
SAVE THE DATE! The next EMBO | EMBL Symposium on 'DNA replication and genome maintenance: from basic biology to disease' will be held October 20-23, 2026.   Organized by Helle Ulrich (IMB), Johannes Walter (Harvard) and Anja Groth (Danish Cancer Institute). www.embl.org/about/info/c...
embl.org
DNA replication and genome maintenance: from basic biology to disease
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Anchel de Jaime-Soguero @ancheldjs.bsky.social · 22/02/2025
Design of a STING fluorescent real time biosensor. Tour de force of my colleague #Steve under Sergio @acebronsp.bsky.social supervision. 👏👏👏
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Anchel de Jaime-Soguero @ancheldjs.bsky.social · 19/02/2025
Novel insights on cellular signaling regulation of DNA replicative dynamics. BMP signaling not only prevents from replicative stress in pluripotency, as we described recently (www.nature.com/articles/s41...) but also drives regeneration through same mechanisms. www.nature.com/articles/s41...
nature.com
BMP signaling promotes zebrafish heart regeneration via alleviation of replication stress - Nature Communications
Zebrafish show robust heart regeneration after injury. Here they show that zebrafish cardiomyocytes experience replication stress, which BMP signaling alleviates via a conserved mechanism of replicati...
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Alfonso Martinez Arias @amartinezarias.bsky.social · 26/01/2025
Surprisingly we find that as few as 2 starting p53KO cells will compete in an environment of @300 WT cells. Also, see an input for BMP & Wnt signalling that mirrors work on the control of chromosomal segregation in stem cells www.nature.com/articles/s41...
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Anchel de Jaime-Soguero @ancheldjs.bsky.social · 27/01/2025
Great work on cell competition during mammalian gastrulation. It aligns with our observations on chromosome stability-driven by morphogens and open further questions on the relation of cellular fitness and genome integrity. Congrats!
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Anchel de Jaime-Soguero @ancheldjs.bsky.social · 20/01/2025
Great city, great environment and cool projects (including stem cell modelling, development, homeostasis and cancer biology). Have a look to the research groups offer and do not hesitate to apply!
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Acebrón @acebronsp.bsky.social · 12/01/2025
Great opportunity for a PhD in Brussels. Outstanding mentor and project addressing bottlenecks in human development
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Anchel de Jaime-Soguero @ancheldjs.bsky.social · 05/01/2025
⚠️📢 Few weeks to close the call. If you love cell & devbio, and are interested on doing a PhD in stress resilisence, please APPLY!
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Anchel de Jaime-Soguero @ancheldjs.bsky.social · 20/12/2024
Gracias a Pilar Perla y @heraldo.es por la difusión de nuestro trabajo en el lab de Sergio Acebrón @acebronsp.bsky.social y mi opinión sobre la investigación básica en mi tierra, Aragón. www.heraldo.es/noticias/ara...
heraldo.es
Anchel de Jaime Soguero: "Aragón necesita dar un impulso a la investigación básica"
Tras pasar por Alemania, el biomédico aragonés lidera su propio grupo en el Instituto Interdisciplinar de Biología Humana y Molecular, en Bruselas.
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Alfonso Martinez Arias @amartinezarias.bsky.social · 17/12/2024
Registration is open for the 12th Advances in Stem Cell Biology Course #ASCBcourse at the @pasteur.fr Hands-on training in different models, embryonic stem cells, iPS cells and much more on #StemCells. 🕘June23-July04, 2025 👉https://qrfy.io/VEcoKQpGfV
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Anchel de Jaime-Soguero @ancheldjs.bsky.social · 26/11/2024
🚨 🚨 Job Alert! I am currently opening my research lab at @iribhm.bsky.social @ulbruxelles.bsky.social in Belgium and I am seeking for an enthusiastic PhD candiate to study cellular stress across mammalian development and lineage specification! If you are interested, info below. Please RT!
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James Briscoe @jamesbriscoe.bsky.social · 04/12/2024
Applications open for a new cohort of @dev-journal.bsky.social *Pathway to Independence* fellows Know a #devbio post-doc about to enter the academic job market? Would they benefit from a little support & mentoring? Spread the word Deadline 31 Jan 2025 journals.biologists.com/dev/pages/pi...
journals.biologists.com
PI programme | Development | The Company of Biologists
PI programme | Development | The Company of Biologists Development's Pathway to Independence programme Development is excited to announce our call for our Pathway to Independence program...
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Anchel de Jaime-Soguero @ancheldjs.bsky.social · 30/11/2024
What a day! An honour to present our work next to these giants and the dynamic belgian stem cell researchers. Great to be back!
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Vincent Pasque @pasquelab.bsky.social · 29/11/2024
It was a fantastic edition of the 8th Meeting of the Belgian Society for Stem Cell Research in Brussels with stellar speakers including Susana de Sousa Lopes, Jacob Hanna, Florian Merkle, Anchel de Jaime-Soguero and many more. Thank you to all participants. #BeSSCR #StemCells
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Anchel de Jaime-Soguero @ancheldjs.bsky.social · 26/11/2024
🚨 🚨 Job Alert! I am currently opening my research lab at @iribhm.bsky.social @ulbruxelles.bsky.social in Belgium and I am seeking for an enthusiastic PhD candiate to study cellular stress across mammalian development and lineage specification! If you are interested, info below. Please RT!
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Anchel de Jaime-Soguero @ancheldjs.bsky.social · 25/11/2024
We recently uncovered that morphogenetic signals not only read our blueprints, but are key to maintain them, particularly in stem cells. Joint effort of numerous collaborations and the lead of Prof. Sergio Acebrón at @cosheidelberg.bsky.social www.nature.com/articles/s41...
nature.com
Developmental signals control chromosome segregation fidelity during pluripotency and neurogenesis by modulating replicative stress - Nature Communications
Here the authors show that the patterning signals WNT, BMP, and FGF control chromosome segregation fidelity during early lineage specification and neurogenesis, which could provide a rationale for the...
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