iiinova — where your digital self keeps evolving

Jack Underwood @jfgunderwood.bsky.social · 31/07/2026

Been a successful year for publications for me, but this one is special. The first language & management guidelines for Timothy syndrome & CACNA1C-Related Disorder, internationally co-produced by experts and the lived experience community, is now published in EJHG (Open Access)!

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The Secret Barrister @barristersecret.bsky.social · 25/07/2026

I regret to inform you that we have reached the “Broadmoor is a holiday camp” stage of right-wing discourse.

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Sergiu P. Pasca @sergiuppasca.bsky.social · 08/07/2026

Our article, led by the remarkable Xiangling Meng, on establishing CRISPR screens in neural #assembloids and #organoids is on the cover of Nature Protocols today

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Dr Kimberley Kendall @drkkendall.bsky.social · 02/07/2026

Thought I'd give this place a go again. I'm Kim. I'm a psychiatrist who does research on genetics and proteomics. I also do a lot of recruitment of people with psychosis for research studies. My clinical work is in a psychiatric genetics clinic in Cardiff.

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Jack Underwood @jfgunderwood.bsky.social · 30/06/2026

Pleased to share our new paper, out open-access in Psychological Medicine. In this work we looked at the relationship between childhood trauma, autism/ autistic traits and depression over a 28 year follow-up in the ALSPAC birth cohort.

cambridge.org

Childhood trauma as a mediator between autistic traits and depression: Evidence from the ALSPAC birth cohort | Psychological Medicine | Cambridge Core

Childhood trauma as a mediator between autistic traits and depression: Evidence from the ALSPAC birth cohort - Volume 56

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Timothy Syndrome Alliance (TSA) @cacna1c.bsky.social · 19/11/2025

New expert-led guidance clarifies terminology for pathogenic CACNA1C variants, defining Timothy Syndrome and introducing CACNA1C-Related Disorders (CRDs). Read the preprint: www.researchsquare.com/article/rs-8... #CACNA1C #TimothySyndrome #RareDisease

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Autism in Adulthood @autisminadulthood.bsky.social · 05/06/2025

“The Experience of Itch in Autistic Adults: An Online Survey” by Tackley et al (2025) finds that autistic adults report greater itch severity and itch-related impact on their daily life than non-autistic adults. FREE until 20th June www.liebertpub.com/doi/10.1089/...

A close-up of a person scratching their arm with their opposite hand.

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Martin McKee @martinmckee.bsky.social · 03/05/2025

3 elections in as many weeks. Centre left parties in two of them take on populist right and win, in 3rd they emulate populists and lose. Could there be a lesson here? And is there even a remote chance U.K. Labour might see it?

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Eberl Lab 👨🏻‍🔬👩🏽‍💻🔬🧫 @eberllab.bsky.social · 24/04/2025

When you were asked to return the corrected page proofs within 48 hours but four months later your paper is still not available online.

media.tenor.com

a man with a mustache is sitting on a swing in a park

ALT: a man with a mustache is sitting on a swing in a park

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Simon Fisher @profsimonfisher.bsky.social · 09/04/2025

"We established four-part assembloids from human pluripotent stem cells, integrating somatosensory, spinal, thalamic & cortical organoids [...to...] accelerate understanding of sensory circuits & facilitate therapeutic development." Elegant work by the @sergiuppasca.bsky.social lab in @nature.com. 🧪

nature.com

Human assembloid model of the ascending neural sensory pathway - Nature

A human ascending somatosensory assembloid model was developed, which integrates multiple organoids to simulate the spinothalamic pathway, demonstrating functional connectivity and responsiveness to s...

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Microplastics Sommelier @leastactionhero.bsky.social · 27/06/2024

einstein sent this to curie in 1911 when she was being harassed by tabloids. it contains everything you’d want in such a letter: (1) your haters are trash (2) you’re a baller, a true queen (3) i have determined the statistical law of motion of the diatomic molecule in planck’s radiation field 🧪⚛️

Prague, 23 November 1911
Highly esteemed Mrs. Curie,
Do not laugh at me for writing you without having anything sensible to say.
But I am so enraged by the base manner in which the public is presently daring to concern itself with you!? that I absolutely must give vent to this feeling. However, I am convinced that you consistently despise this rabble, whether it obsequiously lavishes respect on you or whether it attempts to satiate its lust for sensationalism!
I am impelled to tell you how much I have come to admire your intellect, your drive, and your honesty, and that I consider myself lucky to have made your personal acquaintance in Brussels. Anyone who does not number among these reptiles is certainly happy, now as before, that we have such personages among us as you, and Langevin(3) too, real people with whom one feels privileged to be in contact. If the rabble continues to occupy itself with you, then simply don't read that hogwash, but rather leave it to the reptile for whom i

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Martin McKee @martinmckee.bsky.social · 07/03/2025

🧵 1/11 📚 Our new rapid systematic review, led by @trishgreenhalgh.bsky.social in @bmj.com examines the role of physician associates (PAs) and anaesthetic associates (AAs) in the UK. This is a crucially important question in light of the Leng Review

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Dr Rachel Clarke @drrachelclarke.com · 01/03/2025

Starmer: "You are very, very welcome here in Downing Street. As you heard from the cheers on the street outside, you have full backing across the United Kingdom. We will stand with you and Ukraine for as long as it may take." Proud to be British tonight. #SlavaUkrainii 🇺🇦🇺🇦🇺🇦

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Michel Nivard @michelnivard.bsky.social · 28/11/2024

🚨 This will become a curated list of awesome tools for complex trait genetics, **add yours**! it may become a review in which case those who contribute are invited as co-authors.

github.com

GitHub - MichelNivard/awesome-complex-trait-genetics: A list of awesome tools for complex trait genetics.

A list of awesome tools for complex trait genetics. - MichelNivard/awesome-complex-trait-genetics

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Jay Das-Munshi @jdasmunshi.bsky.social · 22/11/2024

My first post on Bluesky :) We’re hiring! We’re looking for a postdoc research associate, to come work with us in our national population mental health consortium. If you’re into psych epi, public health & tackling mental health inequities take a look ⏬ www.timeshighereducation.com/unijobs/mini...

timeshighereducation.com

Research Associate/Research Fellow in Population Mental Health job with KINGS COLLEGE LONDON | 384309

About us In April 2024, IoPPN, King’s College London led the establishment of a national disseminated population mental health consortium, as part ...

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Sergiu P. Pasca @sergiuppasca.bsky.social · 11/12/2024

Our 2024 CSHL conference on human brain development and stem cell models is in full swing, with over 300 participants! This year’s event features exciting new discoveries and dynamic discussions, driven largely by the energy & insights of trainees #Assembloids #Organoids #Brain #CSHL2024Brain

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Fishbourne Roman Palace @romanpalace.bsky.social · 10/12/2024

A lot of people will tell you we're a Roman Palace. We are in fact a moon-sized super-weapon capable of destroying a planet. (Better with sound).

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Awais Aftab @awaisaftab.bsky.social · 04/12/2024

"Why should our entire built environment be optimized to amuse a sliver of one percent of the population, even granting that it amuses them very effectively?" www.astralcodexten.com/p/book-revie...

astralcodexten.com

Book Review: From Bauhaus To Our House

...

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Dave Jones @welshgasdoc.bsky.social · 03/12/2024

Looking forward to the biggest shakeup of the NHS since the last one…

"Reorganise
to create
the
illusion of progress. We trained hard, but it seemed that every time we were beginning to work as a team,
we would be
reorganised. I was to learn later in life that we tend to meet any new situation by reorganizing, and a wonderful method it can be for creating the illusion of progress
while
producing
confusion,
inefficiency, and
demoralization."
Gaius Petronius Arbiter(d. 66 AD) Roman satirist

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Dr Kate Womersley @katewomersley.com · 03/12/2024

RCPsych needs to move from Twitter to Bluesky! It’s a mental health imperative. Peers are already here.

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Neil Renic @ncrenic.bsky.social · 30/11/2024

“thanks so much for the feedback”

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Robert Howard @profrobhoward.bsky.social · 28/11/2024

Disappointing to see a reviewer use a book review to so push his own ideological view of mental illness and mental health services. www.theguardian.com/books/2024/n...

theguardian.com

An Improbable Psychiatrist by Rebecca Lawrence review – doctor turned patient

A brave memoir from a psychiatrist with severe mental illness that describes a failing system from within

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Eric Fauman (he/him) @ericfauman.bsky.social · 28/11/2024

I am still obsessing over this bone development paper showing bone replacing cartilage and thinking about how this mirrors the evolutionary innovation of a bony skeleton replacing a cartilage body plan. Ontogeny recapitulates phylogeny. www.nature.com/articles/s41...

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Prof Christina Pagel @chrischirp.bsky.social · 27/11/2024

My latest post on what to expect for the NHS this winter open.substack.com/pub/christin... TLDR: looks likely we'll avoid a repeat of disastrous 2022/23 winter, but only by luck 1/6

open.substack.com

What is winter looking like for the NHS?

Worrying signs in A&E for October but we are likely to avoid a repeat of the 2022 nightmare winter

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Techpriest @techpriest.bsky.social · 26/11/2024

Me seeing all the healthcare/psych/MH types appear as followers/mutuals when ~80% of what I post is either unserious/fun or otherwise unrelated to the day job

media.tenor.com

a man with a mustache is sitting in a red car looking out the window .

Alt: a man with a mustache is sitting in a red car looking out the window .

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Sergiu P. Pasca @sergiuppasca.bsky.social · 21/11/2024

Latest paper in Nature this week: an atlas integrating 36 single-cell datasets spanning 26 protocols for making neural #organoids Effort led by B. Treutlein, @fabiantheis.bsky.social and @graycamplab.bsky.social

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Suffolk Broad (aka Anna) 🇬🇧🇵🇱🇪🇺 @annadamski.bsky.social · 20/11/2024

This is the live tracker map of Scottish gritter lorries, each with their own hilarious name, like "Grittin' on wae it", "Sled Zepplin" and "Snow bother". You can find the map here: experience.arcgis.com/experience/9...

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Awais Aftab @awaisaftab.bsky.social · 18/11/2024

I did a version about psychiatry papers back then 😆

An xkcd spin off that I made about types of psychiatric papers

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The Voltage-Gated Calcium Channel Collective @thevgccc.bsky.social · 18/11/2024

The Voltage-Gated #Calcium Channel Collective - a #CACNA1A, #CACNA1B, #CACNA1C, #CACNA1D, #CACNA1E, #CACNA1F, #CACNA1G, #CACNA1H, #CACNA1I & #CACNA1S collaboration alongside researchers and clinicians raising awareness, accelerating knowledge, signposting and empowering our communities. #IonChannels

What is the VGCCC?
Voltage-Gated Calcium Channels act like doors on cells, opening when there's an electrical signal. They let calcium ions* flow in, helping with muscle movement, neurotransmission, and other important body functions.
The genes that represent the Voltage-Gated Calcium Channels are CACNA1A, CACNA1B, CACNA1C, CACNA1D, CACNA1E, CACNA1F, CACNA1G, CACNA1H, CACNA1I and CACNA1S.
In the same way the channels work together like a team to ensure proper cell communication and function, we are collaborating as patient gene groups with a network of researchers to raise awareness and accelerate knowledge for all our gene groups. We are the Voltage-Gated Calcium Channel Collective.

* Calcium ions are positively charged particles of calcium, an essential mineral found in the body.

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Dr. Elena Mikalsen @drelenamikalsen.bsky.social · 17/11/2024

I have a Fellowship open in my division for 2025/2026 for an early career psychologist interested in Autism and Neurodevelopmental Disabilities. Message me for info.

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Jack Underwood @jfgunderwood.bsky.social · 17/11/2024

Got an email that a paper of mine had been cited. Citation is a dross manuscript in a predatory journal; so far, so dull. BUT, the article also included copyrighted media from the charity I work with. No attribution or prior authorisation. Article so bad it would damage the charity rep. Options?

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The Museum of English Rural Life (MERL) @themerl.bsky.social · 14/11/2024

If you're new to Bluesky: welcome! You made it! For any lovers of museums or the arts, we made a Starter Pack containing many museums, galleries and libraries that you can follow and enjoy in a single click. Have any suggestions of accounts we should include? Let us know! bsky.app/starter-pack...

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Ewan Birney @ewanbirney.bsky.social · 14/11/2024

Got a PhD in bioinformatics or quantiative/CS degree? Want to work with AI on real world health care data, using some of the biggest and most complete datasets in the world? Want to live in Cambridge UK and work in European EMBL? This job in my research group is for you! www.embl.org/jobs/positio...

embl.org

EMBL Jobs

We offer a wide range of challenging scientific and non-scientific positions at all of our European locations and encourage applications from international candidates at all career levels.

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Jack Underwood @jfgunderwood.bsky.social · 11/11/2024

In the spirit of academic openness: I got a manuscript rejection today. Big-ish paper and journal, and it had been through a round of review and edits. 3 years of work (and counting). Stings, but we get back on the horse.

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Frances: Meh and Loving It @francesmeh.reviews · 10/11/2024

one of the reasons bluesky works differently is because early users waged a successful fight to get the devs to prioritize safety features to protect communities at risk as a result bluesky now has a suite of controls that i think are unmatched on social media here’s the list, lmk what i’ve missed

A Probably Incomplete List of Bluesky User Safety Mechanisms

Protecting your posts
• disabling replies on your posts
• limiting replies on your posts to people you follow, mention, or include in specific lists
• disabling quote posting on your posts
• detaching your post from someone else's quote
• changing the above interaction settings even after a post is sent hiding replies to your posts for yourself or for everyone
• self-labeling your media for adult or graphic content to protect other users
• limiting account visibility only to logged in users
• note: this is not 100% enforceable but all major bluesky clients and apps support it

Limiting your interaction
• blocking users from seeing or interacting with your posts
• if you block after an interaction, they vaporize
• if they've replied already, the entire thread below their reply is cauterized for everyone, floating in space detached from your post
• note: your blocks are publicly visible via 3rd party apps
• muting users to remove them from your notis and feeds, and hide them in replies
• note: your mutes are private
• muting or blocking entire moderation lists of users
• note: inclusion in a list is public via third party apps. muting a list is private, blocks via a list are public
• subscribing to other people's mod lists
• note: your subscription is private, muting & blocking work the same
• subscribing to labelers (moderation services) from bluesky or third parties
o decide whether to show, warn, or hide posts that have been labeled in each category
• report content that should be labeled to bluesky and/or third parties labelers

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Dr Kate Womersley @katewomersley.com · 08/11/2024

For all things psychiatry, psychology and mental health. Message below if you’d like to be added to the starter pack! go.bsky.app/C36fgiD

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Michel Nivard @michelnivard.bsky.social · 07/11/2024

New here? or logged back in recently? Find your old friends in statistical and psychiatric genetics in this starter pack, ill try to update frequently, let me know if you want to be added: go.bsky.app/9643dwo

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Erin Biba @erinbiba.bsky.social · 26/10/2024

This one is my favorite

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IMS Epidemiology, University of Cambridge @imsepidemiology.bsky.social · 17/10/2024

The 1st national survey of play in preschool-aged children in Britain has found that from the age of two, girls play outside in nature less than boys. The research was by researchers at the Universities of Cambridge & Exeter. Read - buff.ly/3YbzNS3

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Matthew Holehouse @matthewholehouse.bsky.social · 21/10/2024

Why is The Rest Is Politics so popular? Because it harks back to an earlier age of broadcasting: less cynical, less combative, and in which the BBC's John Freeman asked questions like : “Are you on the whole more interested in ideas or in people?” www.economist.com/britain/2024...

economist.com

Why “The Rest Is Politics”, a British podcast, is a hit

Centrism and an old-fashioned approach to broadcasting are at its core

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Jehannine (J9) Austin @j9austin.bsky.social · 19/10/2024

Ok friends! I made a starter pack of psychiatric genetics people! Please let me know if you want to be added and share widely on other platforms to get our community here go.bsky.app/SkkmtMG

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Jack Underwood @jfgunderwood.bsky.social · 25/09/2024

Hello all, another refugee finding my way here. I'm an academic forensic psychiatry SpR interested in all things psychiatric genetics, particularly neurodevelopmental conditions and rare genetic disorders. Also posting about consciousness, AI, sci-fi & economics/politics. Will disagree agreeably.

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