Trials of drugs to fight deadly resistant infections are advancing, but they might fall victim to overuse of agricultural fungicides just like their predecessors.

A subanalysis of 396 candidemia cases diagnosed outside the intensive care unit from the pan-European multicenter ECMM Candida III study showed higher surv

Critical Care - Influenza-associated pulmonary aspergillosis (IAPA) is a frequent and often fatal complication of severe influenza in critically ill patients. Despite increased recognition, its...

Abstract. ECMM-Candida III was a pan-European, multicentre observational study of adult patients with blood culture-proven candidemia. Among a total of 632

AbstractBackground. Endemic mycoses are caused by fungi inhabiting specific ecological niches. These infections remain underdiagnosed and underreported due

Mucormycosis is a severe fungal infection that is challenging to diagnose as traditional methods lack sensitivity and serological testi

This multicenter study evaluated circulating immune biomarkers in patients with invasive aspergillosis to monitor treatment and predict outcome. Several pr

To evaluate the diagnostic performance, particularly specificity, of the MucorGenius® PCR assay for detecting pulmonary mucormycosis in bronchoalveolar lavage fluid (BALF) samples from at-risk patient...

Mucormycosis is a rapidly progressive and fatal fungal infection. Timely diagnosis is critical for effective treatment, yet current diagnostic tools are slow, insensitive, or require complex laborator...

AbstractBackground. Mucormycosis is a severe fungal infection that is challenging to diagnose as traditional methods lack sensitivity and serological testi

Invasive candidiasis is a life-threatening infection associated with high morbidity, mortality and healthcare costs in both general and critical care settings. Timely diagnosis and adequate antifunga....

Background Invasive candidiasis (IC) remains one of the most challenging infections in critical care, contributing significantly to morbidity, prolonged organ support, and mortality among intensive ca...

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Use of some antifungal pesticides may select for resistant fungi in the environment, which can then endanger human health. Coordinated regulatory processes in this area are important.

Candida endophthalmitis and chorioretinitis are uncommon but potentially devastating complications of candidemia, associated with significant risks of vision loss and long-term morbidity. Effective ma...

ECMM Candida IV Antifungal tolerance, resistance and clinical outcomes on candidemia caused by non-albicans Candida  Observation periods/Timeline Observation period: April 1st, 2024 – September 30th, ...

Eine internationale Studie unter Beteiligung der Med Uni Graz erforscht bestimmte Biomarker im Zusammenhang mit Pilzinfektionen.

A drug candidate with a new mechanism of action shows promise against several drug-resistant infections in mice

A drug candidate with a new mechanism of action shows promise against several drug-resistant infections in mice

Background Invasive mould infections (IMI) cause substantial morbidity and mortality in populations at risk. Novel treatment approaches are urgently needed. Targeting immune checkpoints may reverse ...

Despite increasing burden of injecting-related bacterial and fungal infection, there has been no recent synthesis of their epidemiology. We performed a systematic review and meta-analysis evaluating prevalence and incidence of injecting-related infection among people who inject drugs.

Fungal infections are becoming an escalating public health challenge, particularly among immunocompromised individuals. The partially limited efficacy…

Abstract. Illicit drug use in the United States continues to rise, alongside an increasing number of severe infections associated with drug use. Surveillan