MDA5 detects double-stranded RNA during viral infections. This work shows that MDA5 binds aberrant host RNA induced during viral infection. Rescue of aberrant cytoplasmic RNA during infection abrogate...

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(A) We propose that Helicobacter pylori secretes a nucleomodulin, Tumour Necrosis Factor-α-inducing protein (Tipα), predominantly via extracellular vesicles (EVs), also known as outer membrane vesicl...

Fetal growth restriction (FGR) arises from chronic hypoxia and increases the risk of cardiovascular dysfunction following perinatal asphyxia, although underlying mechanisms remain unclear. We investigated whether cardiovascular responses to asphyxia are impaired in preterm FGR lambs and whether this …

Pediatric Research - Commentary on ‘Early diagnosis of serious bacterial infection in febrile infants using type I interferon signature’ by Fueri, Bellini and group

Melbourne researchers have developed a new RNA drug designed to prevent the damaging effects of the debilitating autoimmune disease lupus, in a major breakthrough supported by the Allan Labor Governme...

Abstract figure legend Differences in cardiovascular function between appropriately grown (AG) and fetal growth restricted (FGR) infants after the cardiopulmonary transition at birth. AG infants typi....