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Isa Palstek

@ipalstek.eurosky.social
1.1K followers 605 following 365 posts

Biologist, PhD, loves microscopy, microbiome research & microbiome support. Manages an autoimmune disease. Focus since 2013: wild fermented food and microbiome. www.wildefermente.de

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Reposted by Isa Palstek
Stephen Graham's Lab @atomicvirology.bsky.social · 08/10/2026
Now published in Science Advances @science.org Herpes simplex virus has a single protein that completely silences neuronal activity by removing ion channels from the cell surface 🧠🤫⚡ www.science.org/doi/10.1126/... Bluetorial of the preprint 👇
science.org
Herpes simplex virus pUL56 abolishes neuronal activity by removing voltage-gated ion channels from the plasma membrane
Herpes simplex virus 1 (HSV-1) infections of the central nervous system cause encephalitis and are associated with increased risk of neurodegeneration, yet the molecular consequences of lytic infectio...
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Isa Palstek @ipalstek.eurosky.social · 07/10/2026
med.stanford.edu/news/all-new...
med.stanford.edu
Gut microbes across continents trace ancient human migration
A study of the microbiome of groups in Africa and South America indicates that diverse gut microbes joined us as we migrated out of Africa — a diversity that is lost among industrialized peoples.
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Reposted by Isa Palstek
Matt Olm @mattolm.bsky.social · 07/10/2026
My final postdoc project is out today in Nature! We show microbes co-migrated with humans out of Africa; three independent methods agree, and timing matches archaeological / genetic evidence (Fig. 4c). Seeing Fig. 4c for 1st time was one of my most memorable "eureka" moments! doi.org/10.1038/s415...
doi.org
Prehistoric global migration of vanishing gut microbes with humans - Nature
Microbial species disappearing from industrialized populations have evolved with humans over millennia and migrated worldwide with them—this may have consequences for human health.
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Matt Olm @mattolm.bsky.social · 07/10/2026
Sharable link: rdcu.be/9D1PAYzgMhea Coverage from NYT: www.nytimes.com/2026/10/07/s... Coverage from NPR: www.npr.org/2026/10/07/n... Coverage from Stanford: med.stanford.edu/news/all-new...
nytimes.com
Was the Human Gut Healthier in Ancient Times? (Gift Article)
The microbiome isn’t what it used to be in many parts of the world. The shift may be affecting the well-being of people in industrialized countries.
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Trends in Microbiology @cp-trendsmicrobiol.bsky.social · 06/05/2026
Calling #GameofThrones fans! The May '26 issue of Trends in Microbiology is live now with the cover image depicting the intimate co-evolution between the host and the microbiota. Read the full issue here: www.cell.com/issue/S0966-...
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Stephan P. Rosshart @srosshart.bsky.social · 05/10/2026
Reposts appreciated! Natural microbiota-based mouse models - particularly Wildlings - improve reproducibility & translation across a remarkable range of biomedical fields. Our new @jem.org Found in Translation! Thanks Isabel, Mario & @jonatcoquet.bsky.social! doi.org/10.1084/jem....
doi.org
Natural microbiota–based mouse models: A platform to fast-track translation of fundamental discoveries into the clinic
Conventional laboratory mice are invaluable tools in biomedical research, but their restricted microbial complexity limits their translational relevance. H
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Rockefeller University Press @rupress.org · 05/10/2026
In @jem.org, Gößwein, Ulmert, @srosshart.bsky.social, and @jonatcoquet.bsky.social describe how colonizing laboratory mice with a naturally evolved #microbiota can restore important features of mammalian physiology & how this can benefit translational research. rupress.org/jem/article/...
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APC Microbiome Ireland @apcmicrobiomeirel.bsky.social · 30/09/2026
Could fermented protein foods influence the gut-muscle axis? A new @commsbio.nature.com review by Dominic Farsi, @pauldcotter.bsky.social & @orlaos.bsky.social examines the evidence. Direct muscle evidence remains limited. 📰 buff.ly/WS6RB9R #Microbiome #Nutrition #FermentedFoods
New publication announcement stating "Fermented protein foods may influence the gut‑muscle axis, but direct evidence for effects on muscle remains limited," shown with a journal article screenshot, three author headshots, and a University College Cork logo.
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Samuele Laudani @samuelelaud.bsky.social · 29/09/2026
Very excited to share that our paper from the Benakis Lab is now published in Cell! 🎉🧠 Huge thanks to @benakis-lab.bsky.social for the opportunity to be part of this project! 🚀 www.cell.com/cell/fulltex...
cell.com
Gut microbiota primes stroke severity via the AHR in intestinal dendritic cells
Indole-producing Escherichia coli worsens ischemic stroke through the activation of aryl hydrocarbon receptor signaling in dendritic cells. Limiting AHR signaling in DCs promotes gut-derived DC migrat...
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Tom Gauld @tomgauld.bsky.social · 24/09/2026
My latest @newscientist.com cartoon. many more here: www.newscientist.com/author/tom-gauld/
Image: A graph with lots of red dots clustered together in a curve. The are all looking upwards at a single red dot wearing sunglasses. 

Caption: Mike was an outlier and would probably be excluded from the study, but all the other data points secretly thought he was really cool.
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Michael Baym @baym.lol · 13/09/2026
Ten years ago Tami, Roy, and I released a movie we made of antibiotic resistance evolving in real time. I thought maybe a couple thousand people tops would see it. I couldn't have imagined it would be seen millions of times, and be taught from middle school through the graduate level worldwide
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Benjamin Wolfe @benwolfe.bsky.social · 09/09/2026
Over the past decade, a toxic fungus that destroys cheese rinds has been popping up in cheese caves throughout New England. In a new paper from my lab, we tried to better understand this emerging threat to New England's artisan cheese industry. doi.org/10.1128/aem....
Cheese rinds contaminated with Aspergillus westerdijkiae
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Guillaume Urtecho @gogurtecho.bsky.social · 02/09/2026
Excited to share the first paper from the Urtecho Lab! We built a framework to move fecal microbiota transplantation (FMT) from a black-box therapy to precision medicine for gut disorders 🧵 doi.org/10.1080/19490976.2026.2725403 #Microbiome. #OpenAccess
doi.org
Metagenome-scale modeling to assess microbiome metabolic complementarity for precision microbiota transplantation therapies
Fecal microbiota transplantation (FMT) holds therapeutic promise beyond recurrent Clostridioides difficile infection, but clinical outcomes remain unpredictable and donor-selection strategies remai...
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Dr. Lucky Tran @luckytran.com · 25/08/2026
Do not normalize children dying from measles. Measles was previously eliminated in the US, thanks to vaccines. When children die from measles, it means that adults have catastrophically failed to protect them because they have rejected basic science.
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ISB @isbscience.org · 28/08/2026
Why do some people develop harmful autoantibodies after COVID-19? New ISB-led research in Immunity traces their production to a distinct population of B cells and reveals striking connections to autoimmune disease. isbscience.org/news/infecti... @cellpress.bsky.social @cp-immunity.bsky.social
isbscience.org
ISB Researchers Identify Immune Cells that Drive Harmful Autoantibody Responses After COVID-19
ISB identifies B cells that drive harmful autoantibody production after COVID-19, revealing links between viral infection and autoimmunity.
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Jason Koebler @jasonkoebler.bsky.social · 18/08/2026
“X’s algorithm learns what you hate and shows you more of it, according to a new study just published in the Proceedings of the National Academy of Sciences” www.404media.co/xs-algorithm...
404media.co
X's Algorithm Feeds Off Ragebait and Impacts Democrats More, Study Finds
X is driving engagement by making users fight in the replies.
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Microbiome @microbiomej.bsky.social · 17/08/2026
In #Microbiome Microbially derived glutathione from Eubacterium rectale alleviates oxidative stress and promotes intestinal epithelial recovery🦠 Read more➡️ doi.org/rjc8 #Microbes
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Elaine Hsiao @pipethero.bsky.social · 11/08/2026
Congratulations to Sabeen Kazmi & colleagues on their new study showing that gut microbes & microbial metabolites can promote tau aggregation in a mouse model of tauopathy/Alzheimer’s disease. The work identifies microbiome changes linked to tau risk over time as potential therapeutic targets.
nature.com
Select microbial metabolites promote tau aggregation in a murine tauopathy model - Nature Communications
Here, using a mouse model of tauopathy, the authors reveal that disruption of the gut microbiome drives tau pathology and cognitive decline, and identify five microbial metabolites that directly promo...
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🎃Bushybritches🎃 @bushybritches.bsky.social · 22/07/2026
🤩🤩🤩 This is so cool! A possible new single dose treatment for colon cancer that also acts as an immunization from getting it again. It uses bacteria from tree frogs. Short video if you don’t wanna read the article. youtube.com/shorts/VGvuE... www.sciencedaily.com/releases/202...
sciencedaily.com
This frog bacterium wiped out cancer tumors in mice with a single dose
A naturally occurring bacterium from amphibian intestines completely eliminated colorectal tumors in mice with a single treatment by both attacking cancer cells and activating the immune system. The f...
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jessamyn @librarian.bsky.social · 31/07/2026
I work at a public library. People who want to use AI seem to have no trouble doing so. People who don't want to use AI have a harder time. I crowdsourced and then finalized this document "How to disable or avoid intrusive AI" and then gave it a short URL: notoai.org Please pass along if it's useful
An aircraft passenger oxygen mask: a drop down passenger mask with air bag and yellow plastic mouth and nose cover, oxygen tube has been cut; Demonstration model used by flight attendant crew for passenger instruction. Has text on the side indicating that it's non-functional.
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Universität Jena @uni-jena.de · 31/07/2026
For the first time, researchers from #UniJena and @leibniz-hki.de at @microverse.bsky.social have detected tiny membrane tunnels connecting social amoebae, serving as a communication and transport system. ➡️ www.uni-jena.de/en/434214/amo…
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Oliver @oliver48.bsky.social · 31/07/2026
The thin line between US President policy making satire and reality ... via Arthur Barnes
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Yasin Dagdas @plantophagy.bsky.social · 29/07/2026
If I were an Early Career Researcher (#ECR) today, I wouldn’t join a lab that doesn’t #preprint (the PI agreed to keep paying me until my paper is finally published). It now takes ages to get papers through peer review, and without preprints you’re putting your future in someone else’s hands.
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Prof. Stefan Rahmstorf @rahmstorf.bsky.social · 24/07/2026
Holiday in the climate emergency. No that’s not AI or edited, just a snapshot I just took with my phone on Lacanau beach in France. What future will this boy grow up in? It is in our hands, but time is running out.
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Michael Wagner @michiwagner4.bsky.social · 16/07/2026
"Artificial sweeteners don’t just pass through the body passively - they can interact with gut microbes, and these effects can be amplified or altered by other substances like medication" #MicroSky 🧪 www.the-microbiologist.com/news/sweeten...
the-microbiologist.com
Sweeteners shown to slow growth of important gut bacteria in lab tests
Researchers have shown how commonly-used sweeteners slow the growth of certain gut bacteria. One sweetener in particular - combined with the anti-depressant duloxetine - significantly impaired two imp...
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Eileen Clancy 🧿 @clancyny.bsky.social · 09/07/2026
Gift link! Long read! Our Bacteria Are Talking. We’ve Just Begun to Understand What They’re Saying. By Jeneen Interlandi The human microbiome is essential to our health, but scientists still know very little about it. Two researchers set out to map this largely uncharted terrain.
nytimes.com
Our Bacteria Are Talking. We’ve Just Begun to Understand What They’re Saying.
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DFG RU5042 "miTarget" @ru5042mitarget.bsky.social · 07/07/2026
🎉 Congratulations to Mathieu Groussin and Mathilde Poyet from Project P2 on receiving a Gates Foundation grant to investigate the links between the microbiome and pregnancy! 🧬🤰 Read full article here: www.uni-kiel.de/en/details/n... #Microbiome #PregnancyResearch #GlobalHealth
uni-kiel.de
Groussin and Poyet receive Gates Foundation grant to investigate links between the microbiome and pregnancy
The Gates Foundation is funding a research project  at Kiel University and UKSH investigating the gut microbiome’s influence on the course and outcome of pregnancy
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Rob Waterhouse @rmwaterhouse.bsky.social · 04/07/2026
Horizontal gene transfer (HGT) in ants - several likely underpinning functional innovations, primarily by mediating immune-system adaptations or facilitating nutritional niche expansions academic.oup.com/gigascience/... #biodiversity #genomics
academic.oup.com
Comparative analysis of 163 ant genomes reveals recurrent horizontal gene transfer from bacteria to ants
AbstractBackground. Horizontal gene transfer (HGT) from bacteria can drive phenotypic innovation and adaptation in eukaryotes. Ants are likely carriers of
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DZIF - Deutsches Zentrum für Infektionsforschung @dzif.bsky.social · 30/06/2026
Excited that #DZIF is part of the #REPhRAME consortium: Together with our partners from across Europe, we are advancing innovative approaches to tackle antimicrobial resistance and translate research into better patient care. We look forward to working together! 🚀 t1p.de/6mcot #AMR #HorizonEurope
t1p.de
Viruses against bacteria: EU funds phage therapy with €15 million | German Center for Infection Research
Bacteria are becoming increasingly resistant to antibiotics. One alternative is treatment with viruses that exclusively infect bacteria, known as phages.
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Kate Wong @katewong.bsky.social · 23/06/2026
Today is my last day at Scientific American, which has been sold to LabX media group. For three decades I've led the magazine's coverage of human origins, archaeology, paleontology, animal behavior, ecology, BIRDS. End of an era. Anyway this feels weird to say, but I'm now available for assignments!
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Oded Rechavi @odedrechavi.bsky.social · 23/06/2026
Sad to hear that Carlo Ginzburg, who pioneered "micro history" passed away. "The cheese and the worms" is an incredible book. www.theguardian.com/commentisfre...
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Dirk-Jan Scheffers 🟥 @dirkscheffers.bsky.social · 23/06/2026
‘…the show fills a “critical need” in early childhood development, which is teaching toddlers that the research their parents’ taxes funded belongs to a Dutch corporation.’ 🤣🤣🤣 inpreparation.substack.com/p/elsevier-l...
inpreparation.substack.com
Elsevier Launches Animated Series ‘Paywally And Friends’ To Teach Children Value Of Restricting Information
AMSTERDAM—Academic publishing giant Elsevier announced Tuesday the launch of Paywally And Friends, a new animated series for children ages three to seven that teaches young viewers the importance of r...
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Mel Andrews @bayesianboy.bsky.social · 17/06/2026
When utilized in literature review, LLMs consistently 1. fail to mention female authors in female-led literatures, 2. insist that men are more influential or more heavily cited when this is contradicted by objective citation counts, and 3. attribute women’s work to hallucinated male scholars.
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Simon Kuestenmacher @simongerman600.bsky.social · 18/06/2026
This made me laugh. Here is a London Tube map of the digestive system. Source: buff.ly/23pvsjh
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Ken Timmis @kentimmis.bsky.social · 17/06/2026
the "global biosphere connectome": doi.org/10.1093/fems...
doi.org
Microbes are life, the biological core of One Health and Health in All Policies
The World Health Organization (WHO) is promoting the operative concept of “Health in All Policies” (HiAP; https://iris.who.int/bitstream/handle/10665/11263
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Plague Poems @plaguepoems.bsky.social · 12/06/2026
When you see the story about how the world now has its first trillionaire, and when you see the story about how laboratories in Congo have run out of supplies to test for Ebola, it is important to understand that in many ways these are the same story.
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Aude Bernheim @audeber.bsky.social · 22/05/2026
Great piece and cover @science.org about how our field is uncovering the evolutionary and mechanistic connections between bacterial and eukaryotic immunity ! www.science.org/content/article/ancient-wars-between-microbes-gave-us-key-immune-defenses
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Pádraic Fogarty @whittledaway.bsky.social · 06/06/2026
Wow! 200,000km² of ocean declared entirely off-limits to fishing in some of the most biodiverse waters on earth 🌏 That's a win 🙌 #oceanoptimism oceanographicmagazine.com/news/papua-n...
oceanographicmagazine.com
Papua New Guinea announces largest MPA in its history - Oceanographic
Papua New Guinea has announced the Western Manus Marine Protected Area - a no-take zone covering 200,000 km² of the Pacific Ocean.
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Michael Wagner @michiwagner4.bsky.social · 22/05/2026
"The size of the Ebola outbreak in its initial days is worrying researchers. The next few weeks will determine how large it grows, they say." www.nature.com/articles/d41...
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Alejandro Fábregas-Tejeda @alejandrofabregastejeda.com · 18/05/2026
I am genuinely humbled by the kind words from the first readers of my book! The 📗 is fully #openaccess, made possible by the generosity of libraries worldwide and @mitpress.bsky.social's D2O program: direct.mit.edu/books/oa-mon... Please help spread the word! #booksky #philsci #philsky #histsci
direct.mit.edu
The Organism-Environment Pairing: A Historical and Philosophical Reappraisal
A historical and philosophical exploration of the organism-environment relationship and its role in shaping biological thought.In this first systematic boo
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APC Microbiome Ireland @apcmicrobiomeirel.bsky.social · 08/05/2026
The gut’s nerve signals are part of the autism & gut health research picture. A commentary in 𝐃𝐢𝐠𝐞𝐬𝐭𝐢𝐯𝐞 𝐃𝐢𝐬𝐞𝐚𝐬𝐞𝐬 & 𝐒𝐜𝐢𝐞𝐧𝐜𝐞𝐬 discusses altered intestinal neurotransmission in #autism spectrum disorder, with @valentineturpin.bsky.social @maburto.bsky.social. 📰https://buff.ly/Iw8WIqb #Microbiome
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Adam Schwarz @adamjschwarz.bsky.social · 09/05/2026
Hungary’s parliament sings “Ode to Joy” — the anthem of Europe — after Péter Magyar is sworn in as prime minister. Hungary is once again a proud member of the European Union.
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Xan López @xanlopez.net · 08/05/2026
The European Commission (@ec.europa.eu) has updated the top follow buttons on its web page. Mastodon and Bluesky are in, X is out. commission.europa.eu/index_en
Follow buttons on the European Commission's web page: Mastodon, LinkedIn, Bluesky, Facebook, Youtube, link to other channels.
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FEMS @femsmicro.org · 08/05/2026
What if future antibiotics come from microbes living on social wasps? 🐝 In this #FEMSmicroBlog, Manasa Narayan walks us through how insect-associated Actinobacteria are emerging as promising sources of antimicrobial compounds:
buff.ly
#FEMSmicroBlog: Discovery of Actinobacteria strains associated with social wasps
As antibiotic resistance continues to rise, the search for new antimicrobial compounds is becoming increasingly urgent. While soils have long been the traditional source of antibiotic discovery,…
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Jake Robinson @jake1.bsky.social · 06/05/2026
What happens when people learn that humans are not standalone organisms, but walking ecosystems? Our new paper explored whether learning about the #holobiont concept – humans are symbiotic assemblages of a host & trillions of microbes – influences nature connectedness. 1/
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Stephan P. Rosshart @srosshart.bsky.social · 06/05/2026
Reposts appreciated! What if standard lab mice miss the real microbial game? Honored to be featured on the May cover @cp-trendsmicrobiol.bsky.social: „The microbial companion.“ Our paper “Game of Microbes: A Wildling’s Guide” is out now: dlvr.it/TRl1Zs Thread below with more @cellpress.bsky.social
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Sara Di Rienzi @saradirienzi.bsky.social · 15/03/2026
Cool finding! B. wexlerae converts fatty acids to acyl amines that stimulate GLP1 release.
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Ute Hentschel @utehentschel.bsky.social · 23/04/2026
Brilliant new paper by @tylerjcarrier.bsky.social on how plastid-derived structures help sea urchin development and dispersal. 10.1371/journal.pbio.3003705 @plosbiology.org @geomarkiel.bsky.social @moorefound.bsky.social
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Terrible Maps @terriblemapshq.bsky.social · 22/04/2026
No one does street name trolling quite like Prague
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