Sequencing of oligonucleotide barcodes holds promise as a high-throughput approach for reconstructing synaptic connectivity at scale. Rabies viruses can act as a vehicle for barcode transmission, than...

The execution of coordinated movements depends on the ability to dynamically adapt motor plans to external conditions and perturbations. Spinal circuits integrate motor commands and sensory information in order to generate precise patterns of muscle activation. The detection of different sensory stimuli and their integration with descending commands from the brain and local spinal networks is therefore critical for motor control. Our laboratory studies the mechanisms controlling assembly and function of spinal sensorimotor circuits by combining transcriptomics, genetics, tracing, and behavioral analyses to reveal how these circuits are first organized during development and then function in controlling movement and coding of sensory information.

Most studies of neurological disorders in mice erroneously treat multiple samples from a single animal as independent replicates, according to a new analysis. But scientists and journals can take…

Imaging and optogenetics in mice provide insight into the interplay between the primary motor cortex and the motor thalamus during learning, showing that thalamic inputs have a key role in the executi...

It will be held at the Niigata Convention Center 'Toki Messe' from July 24 to 27, 2025.

The ability to use subjective, latent contextual representations to influence decision-making is crucial for everyday life. The hippocampus is hypothesized to bind together otherwise abstract combinat...

The authors of this Essay examine whether action potentials cause consciousness in a three-step thought experiment that assumes technology is advanced enough to fully manipulate our brains.