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Britton Sauerbrei

@brittonsauerbrei.bsky.social
1K followers 1.1K following 230 posts

Neurophysiologist working on motor control and neural population dynamics. Assistant Prof. at the Case Western Reserve University School of Medicine. sauerbreilab.org

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Reposted by Britton Sauerbrei
John Tuthill @tuthill.bsky.social · 01/10/2026
two new preprints from Wangchu Xiang (@darbly.bsky.social, Ginty labs) about connectomic reconstruction from electron microscopy of somatosensory afferents and projection neurons in the dorsal horn of the mouse spinal cord www.biorxiv.org/content/10.6... www.biorxiv.org/content/10.6...
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Britton Sauerbrei @brittonsauerbrei.bsky.social · 01/10/2026
A great opportunity to work at the cutting edge of motor systems neurophysiology!
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Tessa Montague @tessamontague.bsky.social · 29/09/2026
I'm excited to share our new preprint: Generation of a transgenic cephalopod tinyurl.com/pc86jxz8 Cephalopods (cuttlefish, octopus & squid) are crazy critters that dynamically camouflage to their surroundings by changing the color, pattern, & texture of their skin, which they control w their brain.
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Jeremiah Cohen @jeremiahycohen.bsky.social · 13/04/2026
Delighted to share our discoveries about one of the brain's neurotransmitter systems: www.biorxiv.org/content/10.6... Together with colleagues at the @alleninstitute.org, we have learned a lot about a tiny cluster of neurons in the brainstem locus coeruleus (LC) that releases norepinephrine (NE). 1
biorxiv.org
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(((Dr Hannah Wirtshafter))) 🔬 @aheadofthenerve.bsky.social · 15/09/2026
Hi friends & colleagues! I’m on the hunt for a tenure-track home! I’m a BRAIN Initiative K99/R00 scholar studying learning & memory at the intersection of experimental neuroscience, theory, & machine learning/AI. I’d love to connect & would appreciate help spreading the word! web.mit.edu/hsw/www/
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Michael Hendricks 🇨🇦 @michaelhendricks.bsky.social · 13/09/2026
Thread. Apologies in advance, I've been grinding away for weeks on a grant with maybe a 10% success rate. Canadian researchers work in buildings held together with duct tape, run labs on shoestrings, and spend more and more time competing for lower and lower success rate operating programs.
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Britton Sauerbrei @brittonsauerbrei.bsky.social · 13/09/2026
Fail Safe (1964): worth a watch these days. www.youtube.com/watch?v=AF5M...
youtube.com
Fail Safe (1964)
YouTube video by YouTube Movies
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Drew Schreiner @schreinerdrew.bsky.social · 09/09/2026
I’m on the faculty job market this fall! 🐦🧠 I’m an NIH K99/R00 awardee studying how the brain learns complex skills, using birdsong to connect molecules, synapses, circuits, behavior & computation. Know of a search where I might fit? Please send it my way & share!
drewschreiner.github.io
Drew Schreiner, Ph.D. | Neuroscience of Learning
I use birdsong to understand how the brain learns complex skills across molecules, synapses, circuits, behavior, and computation. On the 2026–27 faculty job market.
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Misha Ahrens @mishaahrens.bsky.social · 09/09/2026
Whole-body cellular activity imaging in zebrafish, headed by Virginie Ruetten @vmsruetten.bsky.social - new paper is out: www.nature.com/articles/s41...
nature.com
Imaging cellular activity across all organs reveals body-wide circuits - Nature
An imaging system developed to record cellular activity throughout the whole body of zebrafish captures cellular organ dynamics and identifies multiple distributed circuits.
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Princeton Neuroscience Institute @princetonneuro.bsky.social · 04/09/2026
We're hiring! PNI is recruiting an assistant professor of neuroscience working with non-human primates in any area. Review begins Oct 19: apply.interfolio.com/192521 #NeuroJobs #Neuroskyence
photo of PNI and psychology building
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Andrew Straw @andrewstraw.bsky.social · 04/09/2026
We are hiring! Come join us in the Straw Lab at the @biologyunifreiburg.bsky.social . Seeking a scientist to work on the neural and computational mechanisms of visual navigation in honey bees. uni-freiburg.de/en/job/00005...
Bee trajectories in agricultural landscape and two photon microscope for in-vivo calcium activity imaging.
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Britton Sauerbrei @brittonsauerbrei.bsky.social · 29/08/2026
A fascinating novel about von Neumann. Recommend.
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Shivani Hariharan @shivanihari.bsky.social · 19/08/2026
Very excited to see our preprint out! 🦇 We show that bats time their echolocation calls to brief dips in rhythmic noise, helping them avoid acoustic jamming. Check it out!
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Britton Sauerbrei @brittonsauerbrei.bsky.social · 20/08/2026
Worth revisiting after four decades.
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Jonathan A. Michaels @jonathanamichaels.bsky.social · 19/08/2026
Looking for a postdoc in motor control / systems neuroscience? I'm seeking candidates to develop a Connected Minds Fellowship proposal with me at York University: $70K/yr for 2 years + benefits, plus an $8.5K/yr research allowance. Deadline: Sept 27, 2026. 🧵
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Ariel Levine @ariellevine.bsky.social · 18/08/2026
We have 2 postdoc positions available to study spinal mechanisms of motor control. Postdoc 1 will focus on how specific spinal cell types shape neural activity www.levine-lab.org jobs.smartrecruiters.com/UniversityHe...
jobs.smartrecruiters.com
Postdoctoral Researcher, Spinal Mechanisms of Motor Control - Neural Activity
Company Description: The University Health Network, where “above all else the needs of patients come first”, encompasses Toronto General Hospital, Toronto Western Hospital, Princess Margaret Canc...
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jhubatlab.bsky.social @jhubatlab.bsky.social · 17/08/2026
What happens when a bat’s eyes and ears disagree? www.biorxiv.org/content/10.6... Dr. Nikita Finger Johns Hopkins University and Medical School
Egyptian fruit bats with prism gogglesEgyptian fruit bats with prism goggles
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The Transmitter @thetransmitter.bsky.social · 17/08/2026
Being able to record from large neuron populations has led to myriad methods to compare them, writes @itsneuronal.bsky.social. But we still grapple with how to convert measures of likeness into better mechanistic understanding. #neuroskyence www.thetransmitter.org/neural-dynam...
thetransmitter.org
Mind over metrics: How can we tell if two brains (or AI models) are alike?
The ability to record from large populations of neurons has triggered the development of myriad methods for comparing them. But we’re still grappling with how to convert measures of likeness into a…
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Abraham Zelalem Vollan @azvollan.bsky.social · 06/08/2026
Now in Science: How does the brain’s navigation system allocate its limited representational resources during behavior? We found that grid cells sweep toward locations of interest, providing a potential mechanism for allocating spatial attention in the cognitive map.🧵 science.org/doi/10.1126/...
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Britton Sauerbrei @brittonsauerbrei.bsky.social · 03/08/2026
Extremely cool!
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Yichen Luo 骆奕辰 @camellyc.bsky.social · 03/08/2026
1/8 Breathing seems automatic. But it's a finely tuned motor behavior that has to be controlled. In this preprint, I map the circuits that match a fly's respiration to the metabolic demands of flight and mitigate the risk of dehydration. 🧵🪰 www.biorxiv.org/content/10.6...
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Cris Niell @crisniell.bsky.social · 03/08/2026
Very happy to share our new review on visual computation in the cephalopod brain, with @vangeliqueallen.bsky.social, out now! We discuss exciting recent advances in understanding how the radically different brain of cephalopods processes the visual scene. 🐙🔬👀 www.sciencedirect.com/science/arti...
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Britton Sauerbrei @brittonsauerbrei.bsky.social · 03/08/2026
The Sauerbrei Lab at Case Western Reserve University is recruiting a postdoctoral scholar to work on neural dynamics and motor control: apply.interfolio.com/189987
apply.interfolio.com
Apply - Interfolio {{$ctrl.$state.data.pageTitle}} - Apply - Interfolio
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Britton Sauerbrei @brittonsauerbrei.bsky.social · 30/07/2026
An extraordinary study of Cezanne’s composition that proceeds by comparison of his paintings with photos of his motifs. One of my favorite examples from the Cleveland Museum: the pigeon house at Bellevue.
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Satpreet (Sat) Singh @satpreetsingh.bsky.social · 29/07/2026
How do you "see" with electric eyes? How does collective behavior emerge from individual interactions? Nocturnal weakly electric fish evolved to do this, but studying naturalistic social behavior is very hard. Our solution? Virtual 'fish' 🤖🐟⚡ 📄 arxiv.org/abs/2511.08436
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Reza Shadmehr @rezashadmehr.bsky.social · 28/07/2026
If an action results in error, each neuron requires an individualized teaching signal that guides change in its output. This is the credit assignment problem of learning. Are there neurons in the brain that can compute such a sophisticated teaching signal? Yes. www.biorxiv.org/content/10.6...
biorxiv.org
Climbing fibers encode the gradient of a loss function for the cerebellum
Neurons in the brain are often many synapses away from motoneurons, yet if a movement results in error, each distant neuron needs a teacher that considers its specific contribution to production of th...
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Ann Kennedy @antihebbiann.bsky.social · 27/07/2026
Happy Monday! Come learn how jellyfish swim. In a review led by fluid dynamics maestro Alex Hoover, we outline how neuromechanical modeling will help us understand how modulation of neural activity allows jellyfish to jet and pirouette through fluids www.sciencedirect.com/science/arti...
Figure 1. The fluid dynamics of jellyfish swimming. a) Minimum intensity projection of a video clip of swimming Clytia hemisphaerica recorded at 30 fps; dark spots capture trajectories of tentacle bulbs, mouth, and gonads over time. Blue outlines approximate the margin of jellyfish on the frame of maximum extent on two successive swim pulses; green arrow shows direction of swimming. b) Minimum intensity projection of the same animal during a period of turning, showing asymmetry in the movement of bulbs on the inside vs outside of the turn. c) 3D diagram of the bell of a swimming jellyfish, showing starting and stopping vortex rings and fluid flow into (blue) vs away from (purple) the bell during the passive energy recapture phase of swimming. d) Cross section of a swimming jellyfish showing fluid vorticity toward the end of a swim pulse relaxation phase, showing locations of the starting and stopping vortex rings and the boundary layer. e) Swim pulse dynamics of an oblate jellyfish under symmetric bell contraction, producing straight swimming. The starting vortex ring is generated by active muscle contraction of the bell (ii, purple arrows), while the stopping vortex ring is generated by passive elastic relaxation (iii-iv, green arrows) from the mesoglea. Forward motion during the relaxation phase arises from the interaction of the starting and stopping vortex rings, with the starting vortex ring pulling fluid away from the bell and the stopping vortex ring directing fluid into the subumbrellar cavity. f) Swim pulse dynamics under asymmetric bell contraction, producing turning. Initially at rest (i), the neuronal signal initiates a muscular contraction in the bell margin on the inside of the turn before a stronger contraction of the bell margin is observed on the outside of the turn (ii-iii, purple arrows). The corresponding passive restoration yields a stronger expansion of the bell margin on the outside of the turn (iv, green arrows).
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Andrew Pruszynski @andpru.bsky.social · 27/07/2026
We're hiring! Postdoc position to study the neural control of reaching using high-density multi-area electrophysiology. 5 years of funding, great collaborative environment. Please share with anyone who may be interested. For details, see: docs.google.com/document/d/1...
docs.google.com
Pruszynski Postdoc 2026
Postdoctoral Researcher, Control Policies in the Primate Motor Circuit Pruszynski Lab @ Sensorimotor Superlab​ The Pruszynski Laboratory at Western University is seeking a postdoctoral researcher to j...
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Britton Sauerbrei @brittonsauerbrei.bsky.social · 23/07/2026
A vital addition to the library!
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yifatprut.bsky.social @yifatprut.bsky.social · 23/07/2026
Exciting news! Our lab has been awarded an ISF-Breakthrough Grant to investigate how subcortical signals shape local and inter-areal cortical interactions during motor learning. We are now recruiting PhD students and postdoctoral fellows. Interested? Send me a message or email.
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Amy Orsborn @neuroamyo.bsky.social · 22/07/2026
🧠 New preprint alert! 🧠 Leo led the heroic effort to improve how we map connections across large cortical networks in macaques—stably—over weeks to years. The secret sauce: a combo of optogenetics + µECoG + new signal processing to localize stim-driven responses. www.biorxiv.org/content/10.6...
biorxiv.org
Combining phase analysis and causal stimulation enables longitudinal mesoscale connectivity mapping
Uncovering the circuit mechanisms of flexible behavior requires characterizing how neural signals propagate across large-scale networks and tracking how those networks evolve over time. Signal propaga...
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Science Magazine @science.org · 21/07/2026
The July 2026 issue of #ScienceRobotics is out! This month's cover features a robot that can switch between different motor skills to jump over logs and navigate varied terrain using a new control framework. Learn about this research and more: scim.ag/4aRI2dk
This month’s cover is a photograph of a quadrupedal robot jumping over a fallen tree trunk.

Credit: Hyungjoon Jeon
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Michael Friendly @datavisfriendly.bsky.social · 19/07/2026
#TodayinHistory #dataviz #Onthisday #OTD 📊 💀Jul 18, 1650 Christopher Scheiner died in Niesse, Poland 🇵🇱 1626: Visual representations used to chart the changes in sunspots over time, the first known use of small multiples, giving a sense of animation
Device used by Scheiner to record sunspots. It consists of a tube which focuses an image of the sun on a plane perpendicular to the axis.
Scheiner's representation of the pattern observed in sunspots over a 40 day period, each day a different circle diagram showing the location of sunspots.
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Ale Santuz @alesantuz.bsky.social · 17/07/2026
Bungee-jumping mice may reveal why astronauts skip on the Moon | Science | AAAS www.science.org/content/arti...
science.org
Bungee-jumping mice may reveal why astronauts skip on the Moon
Low gravity puts a bounce in the step of humans and rodents alike
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stefanofusi.bsky.social @stefanofusi.bsky.social · 15/07/2026
From a great collaboration with @lorenzoposani.com, @shuqiw.bsky.social, Samuel Muscinelli, Liam Paninski, now in Nature: www.nature.com/articles/s41...
nature.com
Rarely categorical, highly separable representations along the cortical hierarchy - Nature
Cortical circuits prioritize diversity over categorical structure, supporting a computational regime geared towards high-dimensional, highly separable neural representations.
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Ben Hayden @benhayden.bsky.social · 16/07/2026
And, of course, Eb Fetz was the prophet of this whole direction, with this paper from 1992, but that reads like it was written 30 years later: depts.washington.edu/fetzweb/asse...
depts.washington.edu
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Niccolò Zampieri @niccolozampieri.bsky.social · 15/07/2026
Thanks @phiejacobs.bsky.social for featuring our work in @science.org! Why did Apollo astronauts skip on the Moon? Our study shows that reduced gravity reveals a proprioception-dependent mechanism for locomotor state selection. @alesantuz.bsky.social leading the way to the moon 🐭🚀
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Joshua Glaser @joshuaiglaser.bsky.social · 13/07/2026
Excited to share this work, led by Andrew Zimnik and Sherry An, from @mchurchland.bsky.social and my labs! www.cell.com/neuron/fullt... 1/2
cell.com
Sparse component analysis: A method that uncovers separable computations within neural population activity
Zimnik et al. provide a new, interpretable, unsupervised dimensionality approach for neural population activity. Their approach, sparse component analysis (SCA), reveals the latent factors correspondi...
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Grace Lindsay @neurograce.bsky.social · 08/07/2026
Neuroscientists: Given that most NHP studies are roughly n=2, what is considered best practice for interpreting results that conflict across monkeys? #neuroskyence
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Britton Sauerbrei @brittonsauerbrei.bsky.social · 04/07/2026
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Britton Sauerbrei @brittonsauerbrei.bsky.social · 04/07/2026
An interesting observation by Warren McCulloch in 1955.
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Britton Sauerbrei @brittonsauerbrei.bsky.social · 30/06/2026
1/N Excited to share a major update to this work, which includes (1) identification of a thalamocortical communication subspace, (2) cortical lesions which induce selective behavioral deficits, and (3) extraction of cortical readouts by EMG decoding. www.biorxiv.org/content/10.1... Thread:
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The Transmitter @thetransmitter.bsky.social · 26/06/2026
An obituary looks back on the life of Avis H. Cohen, who bridged the disciplines of neuroscience, math and engineering to decode lamprey locomotion. By @sarahthau.bsky.social www.thetransmitter.org/locomotion/r...
thetransmitter.org
Remembering Avis H. Cohen, who bridged disciplines to decode lamprey locomotion
The founding director of the University of Maryland’s Neuroscience and Cognitive Science program brought neuroscience, math and engineering together.
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Jeremiah Cohen @jeremiahycohen.bsky.social · 18/06/2026
Excited to move to the Department of Neuroscience at the University of Minnesota in the fall. We will continue our work on neuromodulators and behavior. Positions available in the lab. Please get in touch if interested, and share broadly! hr.myu.umn.edu/jobs/ext/374... hr.myu.umn.edu/jobs/ext/374...
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Jonathan A. Michaels @jonathanamichaels.bsky.social · 17/06/2026
The Neural Control & Computation Lab is recruiting a Postdoctoral Fellow to investigate the neural basis of learning, flexible neural computation, and skilled movement control using large-scale electrophysiology from single-neuron populations in non-human primates 🧠🐒 www.ncclab.ca/join-the-lab
ncclab.ca
Join the Lab — neural control & computation lab
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Nature @nature.com · 15/06/2026
A brain implant is helping a man with paralysis to communicate with his family and friends and to use his personal computer at home go.nature.com/4xN2O7Z
go.nature.com
At-home brain implant gives man with motor neuron disease his daily life back
The device has helped a man with motor neuron disease communicate and control his computer for nearly two years.
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Susan Coltman @susancoltman.bsky.social · 13/06/2026
Homeward bound! After a successful postdoc at Penn State, I'm thrilled to be heading back to Canada to join the University of Guelph faculty in neuroscience and applied cognitive sciences. Bring on the next chapter!
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Jonathan A. Michaels @jonathanamichaels.bsky.social · 12/06/2026
Many of the scientific questions we're interested in tackling require studying learning over long periods of time across the brain. This is challenging – which is why we're excited to say we've been developing a system for chronic wireless recording using long Neuropixels probes in macaque monkeys.
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Andrew Pruszynski @andpru.bsky.social · 10/06/2026
Natural behavior unfolds as a continuous stream of actions. Because these actions often occur in rapid succession, the brain must prepare multiple future actions while the current action is being executed. Our TICS piece explores how this works. www.sciencedirect.com/science/arti...
sciencedirect.com
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The Rockefeller University @rockefeller.edu · 04/06/2026
How can a brain no bigger than a poppy seed offer insights into the mechanisms by which humans navigate the world and make choices? Rockefeller's Gaby Maimon addresses this question, and more, in a #SeekMagazine interview: bit.ly/4ogZv4n
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