Background. Type 2 diabetes (T2D) and coronary artery disease (CAD) frequently co-occur, yet the biological pathways that jointly determine risk remain incompletely understood. Most genetic studies ha...

Results from a panel of assays that analyse different aspects of DNA sequence specificity reveal more than 100 new motifs to aid the characterization of putative human transcription factors.

Changelog Improvements Add partial OmicsPred support by @smlmbrt in #498 Bug fixes Fix compatibility with strict syntax in Nextflow v26 Fix quarto report generation with recent Fusion filesystem...

Genetic prediction of multi-omic data has emerged as a cost-effective alternative to direct omics profiling, particularly useful for identifying molecular features associated with disease susceptibili...

Alt: Mr Bean standing on the beach waiting for access to cohort data

The NHGRI-EBI GWAS Catalog: a curated collection of all published genome-wide association studies, produced by a collaboration between EMBL-EBI and NHGRI

Lead a biomedical data science lab, secure funding, publish research and collaborate globally to drive impactful cardiometabolic outcomes.

University of Cambridge, University of Edinburgh, Imperial College London and University of Oxford Applications are invited for up to 10 funded 4-year PhD studentships starting in October 2026, as

An exciting opportunity has arisen for a new University of Cambridge-Royal Papworth Hospital NHS Foundation Trust Assistant/Associate Professor in Respiratory Medicine. We are seeking applications

An exciting opportunity has arisen for a new University of Cambridge - Royal Papworth Hospital NHS Foundation Trust Assistant/Associate Professor in Cardiology. We are seeking expressions of interest

How to calculate polygenic scores on the UK Biobank Research Analysis Platform

The `pgsc_calc` workflow makes it easy to calculate a polygenic score

The Polygenic Score Catalog Calculator is a nextflow pipeline for polygenic score calculation - PGScatalog/pgsc_calc

The Polygenic Score (PGS) Catalog is an open database of published PGS and the relevant metadata needed to apply and evaluate them correctly.

Friday, October 17th | 11:45AM – 1:15PM | Convention Center room 259A The meeting will open with an introduction (Noel Burtt), include a recap of the landscape analysis (Laura Harris), presentation…

Background Current cardiovascular disease (CVD) risk prediction models place many individuals in an intermediate risk category where clinical decision-making remains uncertain, highlighting a critical...

Nature Communications - Here the authors present a method to transform polygenic scores into disorder probabilities using only GWAS summary statistics, genotype data and a prior - no tuning sample...

Background: Current cardiovascular disease (CVD) risk prediction models place many individuals in an intermediate risk category where clinical decision-making remains uncertain, highlighting a…

Background: Current cardiovascular disease (CVD) risk prediction models place many individuals in an intermediate risk category where clinical decision-making remains uncertain, highlighting a…