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Reposted by Laurent Gil

The Polygenic Score Catalog @pgscatalog.bsky.social · 29/07/2026

A big day for ancestry-specific polygenic risk scores in the PGS Catalog, a phenome-wide atlas of scores for 241 traits (1501 PGS)! Check it out 🔗: www.pgscatalog.org/publication/...!

pgscatalog.org

PGS Catalog - Chen HH, Nature (2025) (Publication)

The Polygenic Score (PGS) Catalog is an open database of published PGS and the relevant metadata needed to apply and evaluate them correctly.

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Reposted by Laurent Gil

The Polygenic Score Catalog @pgscatalog.bsky.social · 04/06/2026

The new v2.3.0 release of pgsc_calc makes our calculator tool fully compatible with scores from the updated @omicspred.bsky.social resource (www.omicspred.org)! Stay tuned for future updates to v3 that improve WGS compatibility next. Github 🔗: github.com/PGScatalog/p...

github.com

Release v2.3.0 · PGScatalog/pgsc_calc

Changelog Improvements Add partial OmicsPred support by @smlmbrt in #498 Bug fixes Fix compatibility with strict syntax in Nextflow v26 Fix quarto report generation with recent Fusion filesystem...

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Reposted by Laurent Gil

Sam Lambert @iamslambert.bsky.social · 20/05/2026

Interested in applying multi-omics imputation or TWAS/PWAS approaches to your data? Frustrated by the models being spread across multiple resources? Enter OmicsPred: a centralised resource for genetic prediction of multi-omic traits! 🔗 : www.omicspred.org 📃 : www.medrxiv.org/content/10.6...

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Reposted by Laurent Gil

Sam Lambert @iamslambert.bsky.social · 20/05/2026

This is a collaborative effort with colleagues @ UChicago (@hakyim.bsky.social) and our Cambridge group (@mikeinouye.bsky.social @cfoguet.bsky.social @laurentgil33.bsky.social @yuxu.bsky.social) + many more! Thanks to authors for making their data open, add yours here: www.omicspred.org/submit!

omicspred.org

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Reposted by Laurent Gil

The Polygenic Score Catalog @pgscatalog.bsky.social · 14/04/2026

Lots of exciting new scores in our latest release! Including: - Multiple metabolic PRS: www.pgscatalog.org/publication/... - First score for Eosinophilic Esophagitis: www.pgscatalog.org/score/PGS012... & much more! Share your data at www.pgscatalog.org/submit!

pgscatalog.org

PGS Catalog - About the Polygenic Score Catalog

The Polygenic Score (PGS) Catalog is an open database of published PGS and the relevant metadata needed to apply and evaluate them correctly.

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Reposted by Laurent Gil

The Polygenic Score Catalog @pgscatalog.bsky.social · 15/12/2025

Wish it was easier to calculate PGS in trusted research environments (TRE) like DNAnexus or the All of Us workbench? Us to! We've been hard at work on a new version of pgsc_calc to make it more scalable in those TREs! Introducing pgsc_calc v3.0.0-alpha.1: pgsc-calc.readthedocs.io/en/v3-alpha.1/

buff.ly

pgsc_calc: a reproducible workflow to calculate polygenic scores | PGS Catalog Calculator documentation.

The `pgsc_calc` workflow makes it easy to calculate a polygenic score

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Reposted by Laurent Gil

The Polygenic Score Catalog @pgscatalog.bsky.social · 11/11/2025

Stay tuned here for upcoming updates to pgsc_calc (github.com/PGScatalog/p...), our tool for reproducible PGS calculation. Our next version aims to increase the scalability to WGS data in cloud trusted research environments (e.g. All of Us).

github.com

GitHub - PGScatalog/pgsc_calc: The Polygenic Score Catalog Calculator is a nextflow pipeline for polygenic score calculation

The Polygenic Score Catalog Calculator is a nextflow pipeline for polygenic score calculation - PGScatalog/pgsc_calc

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Reposted by Laurent Gil

The Polygenic Score Catalog @pgscatalog.bsky.social · 11/11/2025

Another month and lots of new & useful data added to www.PGSCatalog.org! Including new multi-ancestry insulin resistance scores, a score tailored for heart failure in East Asian individuals & more!

pgscatalog.org

PGS Catalog - The Polygenic Score Catalog

The Polygenic Score (PGS) Catalog is an open database of published PGS and the relevant metadata needed to apply and evaluate them correctly.

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Reposted by Laurent Gil

The Polygenic Score Catalog @pgscatalog.bsky.social · 22/07/2025

At #ISMB2025 in Liverpool? Interested in polygenic scores? Ben Wingfield will be back at his poster this afternoon at 4 PM (B507 / TransMed) to discuss all things pgsc_calc - our portable, scalable Nextflow workflow, designed for PGS calculation at scale in TREs! Go say hello!

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Reposted by Laurent Gil

The Polygenic Score Catalog @pgscatalog.bsky.social · 17/06/2025

Check out this PRS (www.pgscatalog.org/publication/...) and more in the latest PGS Catalog data release! Thanks to @pnatarajanmd.bsky.social & co for submitting their scores! See www.pgscatalog.org/submit for information about how to share your work!

pgscatalog.org

PGS Catalog - Flores AM, JAMA Cardiol (2025) (Publication)

The Polygenic Score (PGS) Catalog is an open database of published PGS and the relevant metadata needed to apply and evaluate them correctly.

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Reposted by Laurent Gil

OmicsPred @omicspred.bsky.social · 16/06/2025

We're working closely with our PredictDB colleagues to bring you an integrated resource for multi-omic predictors We're happy to announce that PrediXcan GTExV8 expression predictors are now annotated and openly available via OmicsPred! www.omicspred.org More info www.omicspred.org/publication/...

omicspred.org

OmicsPred is an atlas of genetic scores for prediction of multi-omics data.

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Reposted by Laurent Gil

The Polygenic Score Catalog @pgscatalog.bsky.social · 20/05/2025

Interested in the results of the BARCODE PRS-guided prostate cancer screening study last month in @nejm.org? Just added to the Catalog is the PRS that was used in the cohort: www.pgscatalog.org/score/PGS005.... This and more in the latest release!

pgscatalog.org

PGS Catalog - PGS005205 / Prostate cancer (Polygenic Score)

The Polygenic Score (PGS) Catalog is an open database of published PGS and the relevant metadata needed to apply and evaluate them correctly.

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Reposted by Laurent Gil

The Polygenic Score Catalog @pgscatalog.bsky.social · 31/03/2025

Discover data from our latest release: - New PGS for atrial fibrillation (buff.ly/E1TkmKv) - PGS optimised for East Asian ancestry in cancer (buff.ly/gLkYKVo) and 10 other common diseases (buff.ly/nG7rOIq) Find out how to submit your data here: buff.ly/nJCjUMr

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Reposted by Laurent Gil

Sam Lambert @iamslambert.bsky.social · 01/04/2025

Interested in calculating polygenic scores in the All Of Us workbench? Like those from @pgscatalog.bsky.social? Take a look at our new documentation for how to run pgsc_calc in the cloud environment: pgsc-calc.readthedocs.io/en/latest/ho.... Very much work-in-progress, optimisations incoming!

pgsc-calc.readthedocs.io

Running the PGS Catalog Calculator via the All of Us workbench — Polygenic Score (PGS) Catalog Calculator documentation

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Reposted by Laurent Gil

The Polygenic Score Catalog @pgscatalog.bsky.social · 04/03/2025

📣 Excited to share our new tutorial with @training.ebi.embl.org ! The course covers the basics of polygenic scores and describes the PGS Catalog resources (buff.ly/L8e6a3J, including pgsc_calc), a great overview of the area. Access the course online at buff.ly/CEBWMio!

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Reposted by Laurent Gil

The Polygenic Score Catalog @pgscatalog.bsky.social · 26/02/2025

Also out today is this multi-ancestry PGS for PSA! 🔗: www.pgscatalog.org/publication/...

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Reposted by Laurent Gil

The Polygenic Score Catalog @pgscatalog.bsky.social · 26/02/2025

Now available in the PGS Catalog 🔗: www.pgscatalog.org/publication/...! Thanks to authors like Sean for submitting the data directly, find out how to submit your data at pgscatalog.org/submit

pgscatalog.org

PGS Catalog - Zheng SL, Nat Genet (2025) (Publication)

The Polygenic Score (PGS) Catalog is an open database of published PGS and the relevant metadata needed to apply and evaluate them correctly.

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Reposted by Laurent Gil

OmicsPred @omicspred.bsky.social · 06/02/2025

OmicsPred is developed by @laurentgil33.bsky.social @yuxu.bsky.social @iamslambert.bsky.social @mikeinouye.bsky.social with support from @uniofcam.bsky.social, HDRUK, @ebi.embl.org and the Baker Institute. Many thanks also to @hakyim.bsky.social, Ruidong Xiang, many others! (8/N)

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