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The Polygenic Score Catalog @pgscatalog.bsky.social · 29/07/2026

A big day for ancestry-specific polygenic risk scores in the PGS Catalog, a phenome-wide atlas of scores for 241 traits (1501 PGS)! Check it out 🔗: www.pgscatalog.org/publication/...!

pgscatalog.org

PGS Catalog - Chen HH, Nature (2025) (Publication)

The Polygenic Score (PGS) Catalog is an open database of published PGS and the relevant metadata needed to apply and evaluate them correctly.

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The Polygenic Score Catalog @pgscatalog.bsky.social · 04/06/2026

The new v2.3.0 release of pgsc_calc makes our calculator tool fully compatible with scores from the updated @omicspred.bsky.social resource (www.omicspred.org)! Stay tuned for future updates to v3 that improve WGS compatibility next. Github 🔗: github.com/PGScatalog/p...

github.com

Release v2.3.0 · PGScatalog/pgsc_calc

Changelog Improvements Add partial OmicsPred support by @smlmbrt in #498 Bug fixes Fix compatibility with strict syntax in Nextflow v26 Fix quarto report generation with recent Fusion filesystem...

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The Polygenic Score Catalog @pgscatalog.bsky.social · 14/04/2026

Lots of exciting new scores in our latest release! Including: - Multiple metabolic PRS: www.pgscatalog.org/publication/... - First score for Eosinophilic Esophagitis: www.pgscatalog.org/score/PGS012... & much more! Share your data at www.pgscatalog.org/submit!

pgscatalog.org

PGS Catalog - About the Polygenic Score Catalog

The Polygenic Score (PGS) Catalog is an open database of published PGS and the relevant metadata needed to apply and evaluate them correctly.

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The Polygenic Score Catalog @pgscatalog.bsky.social · 15/12/2025

Wish it was easier to calculate PGS in trusted research environments (TRE) like DNAnexus or the All of Us workbench? Us to! We've been hard at work on a new version of pgsc_calc to make it more scalable in those TREs! Introducing pgsc_calc v3.0.0-alpha.1: pgsc-calc.readthedocs.io/en/v3-alpha.1/

buff.ly

pgsc_calc: a reproducible workflow to calculate polygenic scores | PGS Catalog Calculator documentation.

The `pgsc_calc` workflow makes it easy to calculate a polygenic score

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The Polygenic Score Catalog @pgscatalog.bsky.social · 11/11/2025

Another month and lots of new & useful data added to www.PGSCatalog.org! Including new multi-ancestry insulin resistance scores, a score tailored for heart failure in East Asian individuals & more!

pgscatalog.org

PGS Catalog - The Polygenic Score Catalog

The Polygenic Score (PGS) Catalog is an open database of published PGS and the relevant metadata needed to apply and evaluate them correctly.

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GWAS Catalog @gwascatalog.bsky.social · 14/10/2025

🚨 Countdown to #ASHG25: Predicted Effector Gene standard is coming! 🚨 Join us and be part of the conversation! 📌 Poster Oct 16 | 2:30–4:30 | Poster Hall 🗓️ Session Oct 17 | 11:45–1:15 | Room 259A Learn more: kpnashg2025.wordpress.com/pegs-workshop/

kpnashg2025.wordpress.com

PEGs Workshop

Friday, October 17th | 11:45AM – 1:15PM | Convention Center room 259A The meeting will open with an introduction (Noel Burtt), include a recap of the landscape analysis (Laura Harris), presentation…

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GWAS Catalog @gwascatalog.bsky.social · 15/10/2025

At #ASHG25 and want to meet members of the GWAS Catalog & PGS Catalog teams? Stop by the @impc-phenotypes.bsky.social booth 1420 where we're helping out!

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The Polygenic Score Catalog @pgscatalog.bsky.social · 06/08/2025

Some recent data: - First scores for frailty measurements (@isyfoote.bsky.social & @andrewgrotzinger.bsky.social‬): www.pgscatalog.org/publication/... - Comprehensive comparison of type 2 diabetes PGS in Qatari Biobank: www.pgscatalog.org/publication/... Share PGS 👉 www.PGSCatalog.org/submit!

pgscatalog.org

PGS Catalog - Foote IF, Nat Genet (2025) (Publication)

The Polygenic Score (PGS) Catalog is an open database of published PGS and the relevant metadata needed to apply and evaluate them correctly.

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The Polygenic Score Catalog @pgscatalog.bsky.social · 24/07/2025

Check out the latest and most powerful polygenic scores for body mass index and obesity from @roelofajsmit.bsky.social et al. in the PGS Catalog: www.pgscatalog.org/publication/.... Thanks to the authors for submitting the data pre-publication! Submission information @ www.pgscatalog.org/submit

pgscatalog.org

PGS Catalog - Smit RAJ, Nat Med (2025) (Publication)

The Polygenic Score (PGS) Catalog is an open database of published PGS and the relevant metadata needed to apply and evaluate them correctly.

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The Polygenic Score Catalog @pgscatalog.bsky.social · 22/07/2025

At #ISMB2025 in Liverpool? Interested in polygenic scores? Ben Wingfield will be back at his poster this afternoon at 4 PM (B507 / TransMed) to discuss all things pgsc_calc - our portable, scalable Nextflow workflow, designed for PGS calculation at scale in TREs! Go say hello!

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The Polygenic Score Catalog @pgscatalog.bsky.social · 17/06/2025

Check out this PRS (www.pgscatalog.org/publication/...) and more in the latest PGS Catalog data release! Thanks to @pnatarajanmd.bsky.social & co for submitting their scores! See www.pgscatalog.org/submit for information about how to share your work!

pgscatalog.org

PGS Catalog - Flores AM, JAMA Cardiol (2025) (Publication)

The Polygenic Score (PGS) Catalog is an open database of published PGS and the relevant metadata needed to apply and evaluate them correctly.

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The Polygenic Score Catalog @pgscatalog.bsky.social · 26/05/2025

Great to see so many PGS Catalog IDs in the wild on posters at #ESHG2025, #OpenData and #FAIRdata for all! Users and submitters are the lifeblood of the resource, get in touch if you ever have feedback or suggestions for improvement!

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Sam Lambert @iamslambert.bsky.social · 23/05/2025

Great fun sharing the @pgscatalog.bsky.social at the pre- #ESHG25 course on open-source genomics resources. Thanks to Juliana Cerqueira and Inga Prokopenko for the invite! Looking forward to the rest of the conference!

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The Polygenic Score Catalog @pgscatalog.bsky.social · 20/05/2025

Interested in the results of the BARCODE PRS-guided prostate cancer screening study last month in @nejm.org? Just added to the Catalog is the PRS that was used in the cohort: www.pgscatalog.org/score/PGS005.... This and more in the latest release!

pgscatalog.org

PGS Catalog - PGS005205 / Prostate cancer (Polygenic Score)

The Polygenic Score (PGS) Catalog is an open database of published PGS and the relevant metadata needed to apply and evaluate them correctly.

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Andrea Ganna @andganna.bsky.social · 28/04/2025

🚨 EBI has just lunched a new portal to calculate genetic scores from individual-level genetic data. Check it out 👇. It is very cool! geneticscores.org It is linked with the @pgscatalog.bsky.social This was supported by INTERVENE

geneticscores.org

GeneticScores.org

GeneticScores.org provides tools and data to help AI developers and human health researchers make better polygenic scores

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Sam Lambert @iamslambert.bsky.social · 01/04/2025

Interested in calculating polygenic scores in the All Of Us workbench? Like those from @pgscatalog.bsky.social? Take a look at our new documentation for how to run pgsc_calc in the cloud environment: pgsc-calc.readthedocs.io/en/latest/ho.... Very much work-in-progress, optimisations incoming!

pgsc-calc.readthedocs.io

Running the PGS Catalog Calculator via the All of Us workbench — Polygenic Score (PGS) Catalog Calculator documentation

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The Polygenic Score Catalog @pgscatalog.bsky.social · 31/03/2025

Discover data from our latest release: - New PGS for atrial fibrillation (buff.ly/E1TkmKv) - PGS optimised for East Asian ancestry in cancer (buff.ly/gLkYKVo) and 10 other common diseases (buff.ly/nG7rOIq) Find out how to submit your data here: buff.ly/nJCjUMr

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EMBL-EBI Training @training.ebi.embl.org · 11/03/2025

We're pleased to announce our latest free online tutorial! This is for anyone who wants to find out more about polygenic scores and how to explore the data in the PGS Catalog: www.ebi.ac.uk/training/onl... Produced in collaboration with @pgscatalog.bsky.social

Online tutorial
Polygenic scores and the PGS Catalog
Predicting genetic risks and traits
Access anytime, anywhere

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The Polygenic Score Catalog @pgscatalog.bsky.social · 04/03/2025

📣 Excited to share our new tutorial with @training.ebi.embl.org ! The course covers the basics of polygenic scores and describes the PGS Catalog resources (buff.ly/L8e6a3J, including pgsc_calc), a great overview of the area. Access the course online at buff.ly/CEBWMio!

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The Polygenic Score Catalog @pgscatalog.bsky.social · 26/02/2025

Now available in the PGS Catalog 🔗: www.pgscatalog.org/publication/...! Thanks to authors like Sean for submitting the data directly, find out how to submit your data at pgscatalog.org/submit

pgscatalog.org

PGS Catalog - Zheng SL, Nat Genet (2025) (Publication)

The Polygenic Score (PGS) Catalog is an open database of published PGS and the relevant metadata needed to apply and evaluate them correctly.

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The Polygenic Score Catalog @pgscatalog.bsky.social · 06/02/2025

Welcome @omicspred.bsky.social (www.omicspred.org) to 🦋! OmicsPred focuses on curating genetic scores for omics-traits (genes, proteins, metabolites) to power large-scale association analyses. Check it out!

omicspred.org

OmicsPred is an atlas of genetic scores for prediction of multi-omics data.

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GWAS Catalog @gwascatalog.bsky.social · 20/01/2025

Are you going to #FOG2025? Meet us to learn about the integration of processes with PGSCatalog or metadata generation and harmonisation pipelines for #SumStats. Share your data bit.ly/38rNSjx #openaccess

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The Polygenic Score Catalog @pgscatalog.bsky.social · 26/11/2024

Let's start with introductions! The PGS Catalog is an open database of polygenic scores and the relevant metadata required for accurate application and evaluation. Everything is on our website www.PGSCatalog.org, and our newest publication describes how far we've come: rdcu.be/d1vTG since 2019!

Gif of Julie Andrews singing "Let's start at the very beginning" from Sound of Music.

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The Polygenic Score Catalog @pgscatalog.bsky.social · 27/11/2024

If you're interested in the PGS Catalog Calculator we're hosting a free training webinar @ebi.embl.org on December 4th: www.ebi.ac.uk/training/eve... (registration required). Come along, or catch up with the recording after! cc @iamslambert.bsky.social

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The Polygenic Score Catalog @pgscatalog.bsky.social · 26/11/2024

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