Members of the UK Cilia and Centrosome Network have prepared the following briefing on the UKRI funding pause collating publicly available information:n Background: UKRI has been given a £38.6 billion four-year budget (2026–2030) by the government [1]. This will be divided into 4-streams (buckets) to align with national priorities. Curiosity driven research ...

Latest AlphaFold Database update adds high-value datasets for microbial and viral proteins, generated by specialist communities

Latest AlphaFold Database update adds high-value datasets for microbial and viral proteins, generated by specialist communities

Researchers have revealed how parasites hide thousands of antigens behind a single-colour coat and how disrupting this control could make the parasit...

Humanity’s Last Exam, a multi-modal benchmark at the frontier of human knowledge, is designed to be an expert-level closed-ended academic benchmark with broad subject coverage.

TrypTag is a genome-wide database of the subcellular protein localisation in the unicellular parasite Trypanosoma brucei. The main paper describing this resource is Billington et al., 2023.

YouTube video by MPI-CBG

Discovery by researchers in Dresden and Edinburgh points to new understanding of the onset of ALS.

Both natural and synthetic ciliary arrays exhibit diverse coordination patterns. Proper coordination of cilia is essential for the normal physiology of many organisms, from single cells to humans. Yet...

In the face of metahuman science, humans have become metascientists.

Uechi et al. found that a small-molecule lipoamide dissolves stress granules (SGs) by targeting SFPQ, a redox-sensitive disordered SG protein, alleviating pathological phenotypes caused by amyotrophic...

Uechi et al. found that a small-molecule lipoamide dissolves stress granules (SGs) by targeting SFPQ, a redox-sensitive disordered SG protein, alleviating pathological phenotypes caused by amyotrophic...