The T7 bacteriophage deactivates bacterial defence systems through T7K phosphorylation of nearly all host and phage proteins during infection.

Antony Hyman and Clifford Brangwynne receive their 2023 Breakthrough Prize

Mitochondrial fission promotes antibacterial defense via the mitochondrial unfolded protein response and inducible lipid droplets.

Modern lipid biology has evolved far beyond the traditional view of lipids as simple building blocks or energy substrates. Lipids are now recognised as dynamic regulators of biological structures and…

Liu, Gad et al. develop an approach to purify the endoplasmic reticulum and integrate genetic, structural, molecular and cell biological analyses to identify SLC33A1 as an endoplasmic reticulum oxidiz...