How rigid a tissue is coordinates a crucial period of cell patterning, ensuring that embryos develop the right shape and organise their cell layers correctly at the same time.

Autorino et al. report a feedback loop between Nodal signalling and tissue phase transitions in zebrafish embryos. Nodal alters adhesion, triggering tissue rigidification and reduced porosity, which l...

A new study observed the key signalling role that metabolism plays in controlling the tempo of development.

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