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Florey Lab

@floreylab.bsky.social
580 followers 636 following 58 posts

Cell Biologist interested in lysosomes and different flavors of autophagy…. and having fun

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Florey Lab @floreylab.bsky.social · 25/09/2026
Check it out! Really interesting stuff from my colleague @ianmcgough.bsky.social and his team!
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MOREL Lab / MEMBRAMICS research @membramics-lab.bsky.social · 28/07/2026
together with an interview of @frengerquentin.bsky.social !! see there for details: journals.biologists.com/jcs/article/...
journals.biologists.com
First person – Quentin Frenger
First Person is a series of interviews with the first authors of a selection of papers published in Journal of Cell Science, helping researchers promote themselves alongside their papers. Quentin Fren...
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bioRxiv Cell Biology @biorxiv-cellbio.bsky.social · 09/07/2026
SOLAR Mediates Lysosomal Membrane Repair and Redox Defense www.biorxiv.org/content/10.64898/20…
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bioRxiv Cell Biology @biorxiv-cellbio.bsky.social · 08/07/2026
CASM regulates p62/KEAP1/NRF2 antioxidant responses to lysosome damage www.biorxiv.org/content/10.64898/20…
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Florey Lab @floreylab.bsky.social · 10/07/2026
Please check out our new preprint! We find an unexpected role for #CASM in regulating p62 mediated activation of the KEAP1/NRF2 pathway to initiate a cytoprotective antioxidant transcriptional response. More functions for #CASM in responding to lysosome stress. www.biorxiv.org/content/10.6... 1/2
biorxiv.org
CASM regulates p62/KEAP1/NRF2 antioxidant responses to lysosome damage
Effective lysosome function is essential for health, and declines with ageing and disease. Upon lysosome damage, cells mount a complex stress response to restore homeostasis. Membrane ATG8ylation play...
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Journal of Cell Science @jcellsci.bsky.social · 26/03/2026
Our Cell Scientist to Watch is Helene Knævelsrud @helene-knavelsrud.bsky.social. We spoke to Helene about her career, her research and her advice on mentorship. journals.biologists.com/jcs/article/... #autophagy #kidneycancer #mentorship #conferences #procrastination #advocacy #beer
Helene Knævelsrud
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Florey Lab @floreylab.bsky.social · 14/03/2026
Excited to be on my way to #GRCautophagy2026 to co-chair with @rushika-perera.bsky.social . But first the GRS! See you there
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Journal of Cell Biology @jcb.org · 11/03/2026
Are you headed to #GRC #Autophagy in Stress, Development and Disease next week, and interested in speaking with a JCB editor about publishing? Get in touch with our Executive Editor Tim Spencer, who will be there! ✉️ Email Tim: rupress.org/jcb/pages/ed...
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satooze.bsky.social @satooze.bsky.social · 26/03/2025
I am looking for a post/doc! Are you motivated to study the fundamental questions in autophagy? Have a look!
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Babraham Institute @babrahaminst.bsky.social · 26/01/2026
We are pleased to welcome Prof Sir Jim Smith as the Institute's Interim Director. Read more 👇
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Florey Lab @floreylab.bsky.social · 10/12/2025
Don't miss out on attending the Mar 15-20th 2026 GRC on #Autophagy in Ventura, California! All the latest findings from the field - check out the program and come tell us about your amazing science. www.grc.org/autophagy-in...
grc.org
2026 Autophagy in Stress, Development and Disease Conference GRC
The 2026 Gordon Research Conference on Autophagy in Stress, Development and Disease will be held in Ventura, California. Apply today to reserve your spot.
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Florey Lab @floreylab.bsky.social · 06/11/2025
Don't miss out on hearing all the latest #autophagy discoveries at the 2026 GRC meeting in Ventura, US. We and the amazing line up of speakers look forward to meeting YOU 🫵. Follow link to register!!! www.grc.org/autophagy-in...
grc.org
2026 Autophagy in Stress, Development and Disease Conference GRC
The 2026 Gordon Research Conference on Autophagy in Stress, Development and Disease will be held in Ventura, California. Apply today to reserve your spot.
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Florey Lab @floreylab.bsky.social · 21/10/2025
Check out the line up of amazing speakers at the 2026 GRC Autophagy meeting in Ventura, California, 15-20 March. Register now and share your latest findings. www.grc.org/autophagy-in...
grc.org
2026 Autophagy in Stress, Development and Disease Conference GRC
The 2026 Gordon Research Conference on Autophagy in Stress, Development and Disease will be held in Ventura, California. Apply today to reserve your spot.
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Florey Lab @floreylab.bsky.social · 18/10/2025
Want to hear about the latest #autophagy discoveries? Join us in Ventura California for the 2026 GRC Autophagy meeting 15-20 March. Keynote speakers Sharon Tooze, Eileen White and Ivan Dikic. Registration open now⬇️ Bring your science! www.grc.org/autophagy-in...
media.tenor.com
a man in a tuxedo and suspenders is holding a baton and says science
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Rushika M. Perera @rushika-perera.bsky.social · 17/10/2025
Join us in sunny California for the 2026 GRC Autophagy meeting! Excited to co-chair with Oliver Florey and vice chairs Helene Knaevelsrud and @robzonculab.bsky.social Keynote speakers incl. Eileen White, @idikic.bsky.social and Sharon Tooze- Registration is open: link⬇️ www.grc.org/autophagy-in...
grc.org
2026 Autophagy in Stress, Development and Disease Conference GRC
The 2026 Gordon Research Conference on Autophagy in Stress, Development and Disease will be held in Ventura, California. Apply today to reserve your spot.
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Florey Lab @floreylab.bsky.social · 30/09/2025
Last day in the lab for student Jake @jakecross96.bsky.social. So we had a naming ceremony for a freezer in his honor. Good luck at the @cellbiol-mrclmb.bsky.social
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Florey Lab @floreylab.bsky.social · 22/09/2025
This will end up being another attack on research institutions in the US. I worked in New York on an H1 visa for many years. It benefited me and the lab I was in. Would it have happened if I cost an additional $100,000 per year? www.whitehouse.gov/presidential...
whitehouse.gov
Restriction on Entry of Certain Nonimmigrant Workers
BY THE PRESIDENT OF THE UNITED STATES OF AMERICA A PROCLAMATION The H-1B nonimmigrant visa program was created to bring temporary workers into the United
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Florey Lab @floreylab.bsky.social · 22/09/2025
So, Farage wants to kick out my mum, a French citizen who has lived, worked, paid taxes and raised 2 kids in the UK for over 50 years. I'll make sure to yell at her to "go back to where you came from".
media.tenor.com
a man in a suit and tie is saying `` i have no words '' .
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Florey Lab @floreylab.bsky.social · 07/08/2025
Don't know about him joining ICE.....
media.tenor.com
a man in a superman costume is holding up a metropolitan police mugshot .
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Florey Lab @floreylab.bsky.social · 21/07/2025
Another excellent study showing #CASM at play in plant stress responses!
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Florey Lab @floreylab.bsky.social · 02/06/2025
Neighbors may not like our overgrown lawn. But if it lets wild flowers like this grow, who cares! Bee Orchid #biodiversity
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Florey Lab @floreylab.bsky.social · 06/05/2025
7 months later....BBSRC grant scored 6,6,5,4 (out of 6) - rated excellent. Committee D: Not funded.
media.tenor.com
a man wearing a tuxedo and bow tie is making a funny face .
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Florey Lab @floreylab.bsky.social · 04/04/2025
Sometimes science can wait
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Yamuna Krishnan @krishnanyamuna.bsky.social · 02/04/2025
Unbelievable. Richard Youle, winner of the Breakthrough Prize for Life Sciences, just got fired from the NIH. If you want to know what madness looks like, here it is, my friend.
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Edismauro Freitas-Filho, Ph.D. @efreitasfilho.bsky.social · 29/03/2025
🚀Our latest work reveals how RAB5c orchestrates LC3-associated phagocytosis (LAP) to boost macrophage defense against A. fumigatus! 🦠🔬 🧵 Dive into the mechanisms linking endosomal traffic to innate immunity! #Immunology #Autophagy #Phagocytosis #Macrophage #Preprint doi.org/10.1101/2025...
doi.org
RAB5c controls the assembly of non-canonical autophagy machinery to promote phagosome maturation and microbicidal function of macrophages
Non-canonical conjugation of ATG8 proteins, including LC3, to single membranes implicates the autophagy machinery in cell functions unrelated to metabolic stress. One such pathway is LC3-associated ph...
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lmachesky.bsky.social @lmachesky.bsky.social · 27/03/2025
Congrats to Ian Ganley of Dundee University on winning the #BSCB Hooke Medal 🥇for his outstanding work on mitophagy 🎉🎉🌟
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Max Gutierrez @maxgg.bsky.social · 27/03/2025
Happy to share the latest work from the lab @crick.ac.uk. Outstanding work from Di Chen and Tony Fearns showing the link between Mtb membrane damage, calcium leakage and ATG8/LC3 lipidation in macrophages. Congratulations Di and Tony! www.science.org/doi/10.1126/...
science.org
Mycobacterium tuberculosis phagosome Ca2+ leakage triggers multimembrane ATG8/LC3 lipidation to restrict damage in human macrophages
Ca2+ leakage triggers LC3 lipidation on multimembrane as Mtb phagosome damage response, independent of autophagy.
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Florey Lab @floreylab.bsky.social · 10/03/2025
Twitter suffered an outage….. and I didn’t even notice.
media.tenor.com
a picture of a woman with the words i always found them irrelevant on it
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Florey Lab @floreylab.bsky.social · 19/02/2025
American politics is a joke. With a chief joker. Heartbreaking for the world
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Florey Lab @floreylab.bsky.social · 19/02/2025
I wonder when Trump will start referring to the Ukraine war as "the Russian humanitarian effort"
media.tenor.com
a puppet of donald trump sitting at a desk
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Florey Lab @floreylab.bsky.social · 12/02/2025
Honored to be involved with this event. Celebrating Len and Phill, titans of lipid signalling!
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Florey Lab @floreylab.bsky.social · 22/01/2025
Quick, US colleagues. Add something about Ley Lines and nanobots into your NIH grants! Good luck
media.tenor.com
a woman with curly hair crosses her fingers
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Florey Lab @floreylab.bsky.social · 16/01/2025
Sad. He did some of my favorite screen things.
media.tenor.com
a man in a suit and tie is wearing ear buds and looking at the camera .
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Florey Lab @floreylab.bsky.social · 13/01/2025
Musk and Zuckerberg didn’t do the cage fight thing. But now they are competing to see who’s the biggest douchebag. But wait, a new contender has entered the ring…….
media.tenor.com
a blurry picture of donald trump in a blue suit and white shirt
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Journal of Cell Biology @jcb.org · 11/12/2024
Headed to #CellBio2024 in San Diego this weekend? Come by our booth in the Exhibit Hall to chat about the journal! Pick up a copy of this year's Year in Cell Biology magazine 📙 and grab one of our exclusive puzzles 🧩🎁 See you at booth 520
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Florey Lab @floreylab.bsky.social · 07/12/2024
Happily watching Star Wars A new Hope........ My kids you say? Well, they are on their screens not interested in this "ancient" film
media.tenor.com
a man with a beard and long hair says maybe some day
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Francesco Scavone @fscavone.bsky.social · 22/11/2024
📣 Today's paper in The EMBO J. by tarafisch.bsky.social 👏🥳 "STING induces HOIP-mediated synthesis of M1 ubiquitin chains to stimulate NF-κB signaling" #STING #linear-Ub #K63-polyUb link: www.embopress.org/doi/full/10....
embopress.org
STING induces HOIP-mediated synthesis of M1 ubiquitin chains to stimulate NF-κB signaling | The EMBO Journal
imageimageUpon activation, STING traffics to the Golgi and induces NF-κB signaling through poorly understood mechanisms. This study shows that E3 ligase HOIP recruitment to STING-positive Golgi-relate...
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Florey Lab @floreylab.bsky.social · 17/11/2024
Just moved the Bluesky shortcut to the front of my phone. The “other one” is at the back.
media.tenor.com
a man in a yellow shirt and black tie says i 'm satisfied with the current arrangement ..
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Florey Lab @floreylab.bsky.social · 14/11/2024
I have a joke about western blots, but I’m still developing it. #bringbackscijokes
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Florey Lab @floreylab.bsky.social · 13/11/2024
I was years late to twitter, and probably slow to get here. But here I am.
media.tenor.com
a man in a superhero costume is saying `` no need to worry , i 'm here '' .
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