Abstract. Precise temporal and spatial control of gene expression greatly benefits the study of specific cellular circuits and activities. Compared to chem

University Freiburg Medical Center is a leading institution in biomedical research in the heart of Europe with close associations to other institutions and centers in the tri-national Eucor area (Germ...

Ascorbate peroxidase (APEX) is a versatile labeling enzyme used for live-cell proteomics at high spatial and temporal resolution. However, toxicity of its substrate hydrogen peroxide and background la...

Nature Communications - Human brain organoids are plagued by heterogeneity and poor reproducibility, critical parameters for reliable disease modeling and drug testing. Here, the authors report on...