Klose et al. provide structural insights into a supercomplex between the EMC and Spf1 that brings together cellular machines for membrane protein insertion and extraction into a single entity, providi...

Fungal pathogens often carry dispensable chromosomes (DCs) that confer a selective advantage in adverse environments or during host infection but can be spontaneously lost under non-selective conditio...

Secondary metabolites, including metal chelators and antibiotics, are synthesized by diverse biosynthetic pathways. Here authors find that peatlands harbour extensive biosynthetic novelty, but their a...

Anoxic live-cell imaging shows actin-dependent crawling motility and dynamic protrusions in Asgard archaea, providing insights into cellular innovations that may have contributed to eukaryotic evoluti...

Thallus growth stage affects community-wide capacity for carbon metabolism in the alpine heath lichen Ochrolechia frigida

Author summary Blast, caused by the fungal pathogen Magnaporthe oryzae, is one of the world’s most devastating rice diseases. During infection, M. oryzae secretes a diverse set of molecules, known as ...

This month's ERGA BioGenome Analysis & Applications Seminar will feature talks by Emile Gluck-Thaler and Aaron Vogan on the recently discovered Starship giant transposons and their implications for…

Budding yeast cells can transition from vegetative to filamentous growth under specific environmental stimuli. Saccharomyces cerevisiae has served as a model to understand this process, which is linke...

Structures of Candida albicans class II chitin synthase reveal mechanisms of oligosaccharide translocation and inhibition. The translocation channel is a class II-specific druggable site, and its inhi...

To cause rice blast disease, the filamentous fungus Magnaporthe oryzae develops a specialised infection cell called an appressorium, which generates enormous turgor to breach the rice leaf cuticle. Al...

To cause rice blast disease, the filamentous fungus Magnaporthe oryzae develops a specialised infection cell called an appressorium, which generates enormous turgor to breach the rice leaf cuticle. Al...

Lichens are stable multipartite symbioses in which a fungal mycobiont associates with one or more photosynthetic partners while hosting complex microbiomes. Secreted antimicrobial proteins (AMPs) have...

In bacteria, glutamine synthetase (GS) is the main ammonium assimilation enzyme. Its activity is tightly regulated according to cellular energy status and carbon/nitrogen balance through reversible AM...

Croll lab at University of Neuchatel. The lab of Daniel Croll wants to understand how pathogens evolve to cause disease. For this, we mainly focus on major crop pathogens to unravel mechanisms of rapi...

Abstract. Dikaryotic rust fungi maintain two distinct haploid nuclei for most of their life cycle, making their large, repeat-rich genomes difficult to ass

Temperate Bacillus phages use arbitrium peptides to coordinate lysis–lysogeny decisions, but whether the mature communication peptide can be sensed directly by Bacillus subtilis and affect its physiol...

Gao et al. show that yeast grow faster by proportionally increasing mRNA and ribosome concentrations to increase actively translating ribosomes, while elongation remains constant. A mass-action model ...

A simulation-based approach was developed to design synthetic microbial communities (SynComs) by simplifying complex microbial communities through metabolic modelling. The simulation-based approach w...