Sign in

Josie Maidment

@jmaidment.bsky.social
195 followers 273 following 15 posts

Postdoctoral scientist @phimresearch.bsky.social) &‬ @cbsmontpellier.bsky.social Biochemical/structural studies of proteins to understand plant disease/immunity & improve crop health 🌾🌱 She/her. Views my own.

PostsRepliesMedia
Josie Maidment @jmaidment.bsky.social · 25/09/2026
Happy to share that our study of the interaction between the MAX effector AVR-Pia and rice HMA domain-containing proteins has been published (as the cover article!) in PLOS Pathogens. journals.plos.org/plospathogen...
journals.plos.org
Two folds, many faces: The Magnaporthe oryzae MAX effector AVR-Pia targets novel rice HMA domain-containing proteins
Author summary Blast, caused by the fungal pathogen Magnaporthe oryzae, is one of the world’s most devastating rice diseases. During infection, M. oryzae secretes a diverse set of molecules, known as ...
33219
Reposted by Josie Maidment
Martin Pacesa @martinpacesa.bsky.social · 21/09/2026
ʙɪɴᴅᴄʀᴀꜰᴛ2 is out, and we're not waiting for the paper. The full code drops today, free for academic and industry use. We're releasing it early so you can start designing right now, and bring its full power to the current Adaptyv competition. github.com/PacesaLab/Bi...
4292142
Reposted by Josie Maidment
Milot Mirdita @milot.bsky.social · 16/09/2026
ColabFold 1.6.3 is out! 2.5x faster, pip-installable, ipSAE+pDockQ2 scores. Thanks Choonghwan Lee, Marielle Russo, Gyuri Kim 🐍pip install colabfold[alphafold] CF2 Sneak Peak with AF3/Boltz/Protenix/ESMFold2… 🐍pip install "colabfold[alphafold3]@git+https://github.com/sokrypton/ColabFold@af3-preview"
29736
Reposted by Josie Maidment
Plant Physiology @plantphys.bsky.social · 04/09/2026
🚨Plant Physiology Assistant Features Editors Application Closing Next Tuesday, September 8!🌱 Learn more and apply now!👉https://blog.aspb.org/plantphys_afe_recruitment_2026/. #PlantScience #PlantSci
0105
Reposted by Josie Maidment
Michael Hothorn @structplantbio.bsky.social · 05/08/2026
Out in @natplants.nature.com, mapping of brassinosteroid chemical features required for (1) receptor binding, (2) ligand positioning and (3) co-receptor recruitment. Fantastic work by Alberto Caregnato & @hmchen93.bsky.social and our friends in Olomouc. Funding:@snf-fns.ch -> doi.org/10.1038/s414...
15831
Reposted by Josie Maidment
Nitzan Shabek @shabeklab.bsky.social · 05/08/2026
check out our latest review. Beyond prediction: Why experimental structural biology remains essential in plants. www.sciencedirect.com/science/arti...
sciencedirect.com
Beyond prediction: Why experimental structural biology remains essential in plants
Structural biology is undergoing a transformative era driven by advances in artificial intelligence (AI)-based protein structure prediction and cryo-e…
2199
Reposted by Josie Maidment
Plant Physiology @plantphys.bsky.social · 06/04/2026
#ASPBPlantPhysMonday #ICYMI
001
Reposted by Josie Maidment
Plant Physiology @plantphys.bsky.social · 24/02/2026
100 Years of Plant Physiology! How has the journal impacted your career? Submit a 90-second video for our Centennial Competition. Winning videos will be shared on social media & featured at #PlantBio2026 in Ottawa (July 18–22). Details: blog.aspb.org/100-years-of... #PlantPhys100 #PlantScience
Image Text: Plant Physiology Centennial Story Contest Ad. Featuring Plant Physiology and ASPB logos.
0179
Reposted by Josie Maidment
Michael Hothorn @structplantbio.bsky.social · 23/03/2026
New method paper from Alberto Caregnato and former PhD student @hohmannulrich.bsky.social. A tailored crystallisation screen for plant receptor kinase ectodomains, with examples from our lab and from @cellsensing.bsky.social. Check it out: www.biorxiv.org/content/10.6...
04224
Reposted by Josie Maidment
Bruno Ngou @brunongou.bsky.social · 24/03/2026
Cell-surface receptors play key roles across many biological processes. In plants, these receptor families have undergone remarkable expansion. Here, we systematically review these receptors in @theplantjournal.bsky.social Happy to see this out! onlinelibrary.wiley.com/doi/10.1111/...
onlinelibrary.wiley.com
Plant cell surface receptors
Plant cell surface receptors have evolved to perceive peptides, proteins, glycans, lipids, and small molecules through diverse ectodomains, integrating these inputs into distinct physiological output....
23823
Reposted by Josie Maidment
Team Thomma @teamthomma.bsky.social · 14/02/2026
📣 Our latest story just dropped on bioRxiv:: A structurally unique effector shared between Verticillium dahliae and Fusarium oxysporum is involved in cotton defoliation and virulence on other hosts www.biorxiv.org/content/10.6... 🧵
biorxiv.org
34630
Reposted by Josie Maidment
Center for Structural Biology (CBS Montpellier) @cbsmontpellier.bsky.social · 18/02/2026
Discover and share the CBS Montpellier starter pack, to follow current and formers members of the Centre de Biologie Structurale on Bluesky. go.bsky.app/G682pvP @cnrs.fr @inserm.fr @umontpellier.bsky.social
056
Reposted by Josie Maidment
Martin Steinegger 🇺🇦 @martinsteinegger.bsky.social · 30/01/2026
FoldMason is out now in @science.org. It generates accurate multiple structure alignments for thousands of protein structures in seconds. Great work by Cameron L. M. Gilchrist and @milot.bsky.social. 📄 www.science.org/doi/10.1126/... 🌐 search.foldseek.com/foldmason 💾 github.com/steineggerla...
science.org
Multiple protein structure alignment at scale with FoldMason
Protein structure is conserved beyond sequence, making multiple structural alignment (MSTA) essential for analyzing distantly related proteins. Computational prediction methods have vastly extended ou...
4302147
Reposted by Josie Maidment
Société Française de Phytopathologie @sfp-france.bsky.social · 13/01/2026
#JJC2026 @fmartin54.bsky.social gives us an amazing evening talk about his 45-year career on forest ecosystems, ectomycorrhizae, fungal genomics and mycobiome research
1185
Reposted by Josie Maidment
Société Française de Phytopathologie @sfp-france.bsky.social · 13/01/2026
Bruno Le Cam @irhs-angers.bsky.social is kicking off the #JJC2026 conference on #Mycology and #Phytopathology. 4 days of science in the scenic mountains of #Aussois!
02110
Josie Maidment @jmaidment.bsky.social · 13/01/2026
Delighted to be attending (and sharing our latest results!) at the Journées Jean Chevaugeon (@sfp-france.bsky.social) #JJC2026 this week 🌱 Looking forward to the great science and connecting with fellow researchers over the coming days - all in this wonderful location!
1105
Reposted by Josie Maidment
Isabel saur @izzysaurlab.bsky.social · 10/01/2026
Wei Shi @wshisky.bsky.social & Merle‘s work is online. Wei really pushed this work from scratch and Merle linked it to MLA diversification…3rd (co-)first author paper in her PhD. Very proud PI! And only possible through collaboration with G. Döhlemann, @grandpahiro.bsky.social &, Matt Platre. (1/x)
doi.org
Targeting of the barley cell-surface receptor SRF3 by the Blumeria hordei effector AVRA13 overlaps with AVRA13 recognition by MLA and the induction of NLR-mediated cell death.
Pathogens secrete effector proteins to promote virulence. Despite their recognition by barley Mla resistance genes, the structurally-related Blumeria hordei ( Bh ) AVRA effectors are maintained in the...
44936
Reposted by Josie Maidment
Florent Delhommel @florentdelh.bsky.social · 07/01/2026
Our latest work is now out in @cp-molcell.bsky.social ! We have looked at Sgt1, an essential Hsp90 co-chaperone in yeast. We determined its interaction with Hs90 and showed that it stabilises the chaperone-client complex and prevents its dissociation by Aha1. www.cell.com/molecular-ce...
Schematic showing the function of Sgt1 in yeast.
242
Reposted by Josie Maidment
New Phytologist @newphyt.bsky.social · 07/01/2026
Mismatch screening in Nicotiana benthamiana to explore Pik-1/Pik-2 paired NLR platforms for receptor engineering Yuxuan Xi (席玉轩) and Mark J. Banfield nph.onlinelibrary.wiley.com/doi/10.1111/... #PlantScience
Pik pairs as resources for determining optimal ‘chassis’ for engineering recognition.
0106
Reposted by Josie Maidment
Bruno Ngou @brunongou.bsky.social · 22/12/2025
We wrote a review on the mᴏdular properties of plant cell-surface receptors, and how this knowledge can be used to reprogram and engineer them: www.sciencedirect.com/science/arti...
sciencedirect.com
A guide to designing cell-surface receptors in plants
Cell-surface receptors perceive environmental cues and trigger appropriate responses. In plants, these receptors comprise ectodomain, juxta-membrane, …
12417
Reposted by Josie Maidment
Maël Baudin @baudinmael.bsky.social · 05/01/2026
🧬 New preprint on fungal effector 🍄🍎 We identify AvrRvi6, the first AVR from Venturia inaequalis. AvrRvi6 is a MAX effector with apoplastic activity, expanding the functional landscape of this major effector family. 📄 bioRxiv: www.biorxiv.org/content/10.6...
biorxiv.org
Ancient MAX Effector Variants of a Fungal Pathogen Evade Apoplastic Immunity in Apple
Venturia inaequalis is an Ascomycota fungus responsible for apple scab, the main disease in apple orchards. During infection, the pathogen colonizes the subcuticular space and secretes hundreds of eff...
02517
Reposted by Josie Maidment
bioRxiv Microbiology @biorxiv-microbiol.bsky.social · 26/12/2025
Ancient MAX Effector Variants of a Fungal Pathogen Evade Apoplastic Immunity in Apple www.biorxiv.org/content/10.64898/20…
053
Reposted by Josie Maidment
Mary Williams @PlantTeaching @plantteaching.bsky.social · 01/10/2025
Profile of @plantphys.bsky.social EIC Yunde Zhao & RUBY reporter his lab developed; free for use in academic labs & classrooms. “RUBY is making a difference in so many ways because we opened it up to all of science". "Fundamental research is crucial because it can lead to unexpected discoveries.”
today.ucsd.edu
Seeing Red: A UC San Diego Invention is Transforming the Way Scientists Track Genes
UC San Diego biologists have created a transformative new way to monitor genes. The game-changing tool known as RUBY is an inexpensive, easy-to-use technology that allows researchers to visualize gene...
1288
Josie Maidment @jmaidment.bsky.social · 02/10/2025
Deeply saddened by this news. A truly incredible woman who has done so much for so many. "Find your reasons for hope and let them guide you onward." Jane Goodall, The Book of Hope 🌱 www.bbc.com/news/live/c9...
bbc.com
'An extraordinary legacy': Tributes after chimpanzee expert Jane Goodall dies age 91
The primatologist was a
011
Reposted by Josie Maidment
Martin Pacesa @martinpacesa.bsky.social · 27/08/2025
Exciting to see our protein binder design pipeline BindCraft published in its final form in @Nature ! This has been an amazing collaborative effort with Lennart, Christian, @sokrypton.org, Bruno and many other amazing lab members and collaborators. www.nature.com/articles/s41...
14305109
Reposted by Josie Maidment
bioRxiv Plant Bio @biorxiv-plants.bsky.social · 27/08/2025
An activated wheat CCG10-NLR immune receptor forms an octameric resistosome www.biorxiv.org/content/10.1101/202…
053
Reposted by Josie Maidment
Mary Williams @PlantTeaching @plantteaching.bsky.social · 27/07/2025
A whole bunch of Assistants Features Editors from @theplantcell.bsky.social and @plantphys.bsky.social getting to know each other 💚 #PlantBio2025
A great group of young scientists.
27917
Reposted by Josie Maidment
Mary Williams @PlantTeaching @plantteaching.bsky.social · 26/07/2025
#PlantBio2025. Be sure to stop by the ASPB booth in the exhibition hall to learn about the AFE program. We have more than 20 AFEs at the conference! 👉 The Plant Cell is accepting applications for Assistant Features Editors share.google/wqUgOmxQYW4u... Apply by September 15 #PlantBio
share.google
The Plant Cell is accepting applications for Assistant Features Editors | Plant Science Today
Are you an early career researcher passionate about plants and science communication? The Plant Cell is accepting applications for new Assistant Features Editors (AFEs) to begin in 2026 and 2027.
03216
Josie Maidment @jmaidment.bsky.social · 26/07/2025
Excited to be in Milwaukee for the @plantphys.bsky.social editorial board meeting and Plant Biology conference #PlantBio25 🌿 Very grateful to the Plant Phys AFE program for this opportunity and looking forward to great discussions over the coming days!
150
Reposted by Josie Maidment
Qun Liu @qunliu07.bsky.social · 17/07/2025
Our paper is now online in Science Advances! Congrats @saskiahogenhout.bsky.social @johninnescentre.bsky.social and all coauthors! www.science.org/doi/10.1126/...
science.org
Aphid effectors suppress plant immunity via recruiting defense proteins to processing bodies
Aphids hijack plant immunity via p-bodies, but plants fight back with a heat shock protein in an unexpected twist on defense.
05925
Reposted by Josie Maidment
Mariana Schuster @marischuster.bsky.social · 14/07/2025
I am looking for a (bio)chemist to join the lab and help us making affinity-based probes for proteases! The project is truly interdisciplinary with a strong computational chemistry component, peptide synthesis and plant biochemistry! Text me if interested and please spread the word!
02339
Reposted by Josie Maidment
Yu Sugihara @yusugihara.bsky.social · 16/07/2025
🎉 Exciting news during #2025ISMPMI Our AlphaFold sensor vs helper NLR paper is now published in @newphyt.bsky.social‬! Big thanks to the reviewers for their constructive feedback 🙏 📖 Check out the peer-reviewed version here 👇 🔗 nph.onlinelibrary.wiley.com/doi/10.1111/... bsky.app/profile/yusu...
nph.onlinelibrary.wiley.com
Can AI modeling of protein structures distinguish between sensor and helper NLR immune receptors?
Click on the article title to read more.
14316
Josie Maidment @jmaidment.bsky.social · 17/07/2025
After great talks at #2025ISMPMI on de novo design of pathogen protein binders for receptor engineering - perfect timing for this preprint from colleagues at the Centre de Biologie Structurale!
050
Reposted by Josie Maidment
Dani Stevens, Ph.D. @danimstevens.bsky.social · 16/07/2025
#2025ISMPMI 📣 In silico screening of PRR-epitope interactions is now possible! Here, we developed mamp-ml to predict their immunogenic outcomes without structural context. Let's accelerate engineering plant receptors for robust resistance! 🚀🌱 Small 🧵 www.biorxiv.org/content/10.1...
biorxiv.org
mamp-ml: A deep learning approach to epitope immunogenicity in plants
Eukaryotes detect biomolecules through surface-localized receptors, key signaling components. A subset of receptors survey for pathogens, induce immunity, and restrict pathogen growth. Comparative gen...
17741
Josie Maidment @jmaidment.bsky.social · 15/07/2025
Very happy to share our preprint on heavy metal associated (HMA) domain-containing rice proteins bound by the rice blast MAX effector AVR-Pia! 🌾
0136
Josie Maidment @jmaidment.bsky.social · 14/07/2025
Such a great evening with past and present members of the CIME team! #2025ISMPMI @phimresearch.bsky.social
072
Reposted by Josie Maidment
International Society for Molecular Plant-Microbe Interactions @ismpmi.bsky.social · 14/07/2025
Connections are in action in Cologne! At #2025ISMPMI, the poster sessions aren’t just about groundbreaking research—they’re about meeting peers, collaboration, and sharing ideas that move plant-microbe science forward. Full poster hours here: bit.ly/44LqCvc #plantscience #networking
1198
Reposted by Josie Maidment
Angus Bucknell @ahbucknell.com · 14/07/2025
Big thanks to everyone who stopped by my poster today at #2025ISMPMI! For those that missed it, you can check it out on Zenodo! zenodo.org/records/1588...
zenodo.org
Engineering new-to-nature immune sensors for novel recognition of Magnaporthe oryzae
Phytopathogenic fungi significantly impact global food security, causing up to 40% of annual crop yield losses worldwide. Alone, the blast fungus Magnaporthe oryzae has a global economic impact of $66...
01910
Josie Maidment @jmaidment.bsky.social · 13/07/2025
Looking forward to the start of #2025ISMPMI today! If you're interested in structural studies of effector/host target complexes, come talk to me! 🗣️ Talk: Thurs 17th 16:25 Concurrent session "Structure Informed Synthetic Biology: From Design To Function" 📄 Poster: P-212, Thurs 17th 13:30-15:15 🌱🦠
073