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Eyal Rozenfeld

@eyalrozenfeld.bsky.social
190 followers 170 following 18 posts

Neuroscientist | Leon Levy Scholar, Postdoctoral fellow at the Dayu Lin Lab @NYU | PhD at the @MosheParnas Lab | scholar.google.com/citations?user=4…

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Reposted by Eyal Rozenfeld
Dayu Lin @moccalin.bsky.social · 26/08/2026
Happy to share our new study comparing aggression level across 7 strains of mice, led by a talented undergraduate student, Xiuzhi Dai. Strain differences in aggression can be explained a lot by differences in the physiological properties of VMHvl cells. www.nature.com/articles/s41...
nature.com
Hypothalamic representation of aggressiveness across mouse strains - Nature Communications
Genetics profoundly influences aggression by shaping neural circuits, but the underlying mechanisms remain unclear. Here, authors show that strain differences in male mouse aggression are linked to di...
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Dayu Lin @moccalin.bsky.social · 15/07/2026
Happy summer! Share my short review on Oxytocin in Social Conflict. Full text link below. urldefense.com/v3/__https:/...
urldefense.com
Oxytocin in social conflict
Nature Reviews Endocrinology - Although oxytocin is widely known as the ‘love hormone’, it is also released during social conflict, promoting acute social defence and facilitating...
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Dayu Lin @moccalin.bsky.social · 14/05/2026
Happy to share our new review on Neural Mechanisms of Social Hierarchy across Species. We discussed different routes to achieve high social status across species, from fish to humans, and the neural circuits that support each of those strategies. www.nature.com/articles/s41...
nature.com
Neural basis of social hierarchy across species
Nature Reviews Neuroscience - Structured social hierarchies, in which individuals differ in their access to resources and influence over other group members, are a characteristic of many social...
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Dayu Lin @moccalin.bsky.social · 15/04/2026
What has changed in mama bear brain (well, actually mice) to make her risk her life to attack a potential threat and protect her young? Oxytocin is the key! Happy to share our new study led by two awesome postdocs: Takashi Yamaguchi and Rongzhen Yan. www.nature.com/articles/s41...
nature.com
The neural mechanisms supporting the rise and fall of maternal aggression - Nature
In mice, female aggression is governed by an amygdala–to–medial hypothalamus circuit that is strengthened during pregnancy and is dynamically amplified by oxytocin during lactation.
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mosheparnas.bsky.social @mosheparnas.bsky.social · 11/02/2026
1/6 Check out our new study in @currentbiology.bsky.social that examines how our brain accommodates for two opposing demands - efficient and yet accurate learning. 🧵👇
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mosheparnas.bsky.social @mosheparnas.bsky.social · 03/02/2026
Congratulations Shai! Very proud to be a part of this project.
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Shai Israel @shaisrael.bsky.social · 03/02/2026
Super excited to share that the “sequel” to my PhD research at the Parnas lab has been published as a featured article in Communications Biology! 🧵👇 www.nature.com/articles/s42...
nature.com
A new system for studying neuronal remodeling and its relation to behavior in Drosophila - Communications Biology
Authors show that the adult Moonwalker SEZ neuron is a developmentally-conserved larval neuron that drives backward locomotion at both larval and adult stages and undergoes ec...
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Andrew Lin @andrewclin.bsky.social · 01/09/2025
Excited to share our latest work - expressing the bacterial sodium channel in fly Kenyon cells surprisingly *decreases* their excitability, thanks partly to decreased endogenous sodium channels. This prevents learning and decreases odor-evoked calcium influx doi.org/10.1113/JP28...
doi.org
Ectopic sodium channel expression decreases excitability of Drosophila Kenyon cells
Abstract figure legend: We tested the effects of expressing the bacterial voltage-gated sodium channel NaChBac in the Kenyon cells of the Drosophila memory centre, the mushroom body. NaChBac expressi...
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Dayu Lin @moccalin.bsky.social · 09/05/2025
Congrats, Eyal! A great way to start.
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NYU Grossman School of Medicine Postdoctoral Affairs @nyumedpostdocs.bsky.social · 08/05/2025
✨😀Congratulations to postdocs Eyal Rozenfeld and Francesco Limone on being named 2025 Leon Levy Scholars by The New York Academy of Sciences! @sciencelemon92.bsky.social @eyalrozenfeld.bsky.social @moccalin.bsky.social @liddelowsa.bsky.social www.nyas.org/press-releas...
nyas.org
The New York Academy of Sciences and the Leon Levy Foundation Announce the 2025 Leon Levy Scholars in Neuroscience - NYAS
The New York Academy of Sciences and the Leon Levy Foundation have announced the 2025 class of Leon Levy Scholars in Neuroscience.
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mosheparnas.bsky.social @mosheparnas.bsky.social · 20/03/2025
1/ Check out our Juila Manoim, Tal Camchy, @eyalrozenfeld.bsky.social, Hadas Lerner, Hao-Hsin Chang, Ran Darshan, and Ya-Hui Chou new study in @currentbiology.bsky.social. www.sciencedirect.com/science/arti...
sciencedirect.com
Nonlinear high-activity neuronal excitation enhances odor discrimination
Discrimination between different signals is crucial for animals’ survival. Inhibition that suppresses weak neural activity is crucial for pattern deco…
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Tal Laviv @lavivtal.bsky.social · 20/02/2025
I started my lab more then 4 years ago, and we have endured some very challenging times ever since.…I am very excited to share the first paper from my lab, published now in @naturemethods.bsky.social www.nature.com/articles/s41...
nature.com
Genetically encoded biosensor for fluorescence lifetime imaging of PTEN dynamics in the intact brain - Nature Methods
A first-in-class fluorescence lifetime-based FRET sensor for phosphatase and tensin homolog (PTEN) enables the dynamic monitoring of PTEN activity in cultured cells and in vivo with high spatiotempora...
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Wolf Huetteroth @wolfhuette.bsky.social · 10/02/2025
Our story about flies on carousels is out in @currentbiology.bsky.social! After formally engaging the fantastic @clarahowcroft.bsky.social and integrating helpful reviewer feedback, we present a more concise story with detailed behavioural quantification and cooler videos! doi.org/10.1016/j.cu...
media.tenor.com
a dog sits on a merry go round while a boy sits on a scooter
ALT: a dog sits on a merry go round while a boy sits on a scooter
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Sean Piantadosi @piantadosisean.bsky.social · 31/01/2025
So happy to see this paper out! Congrats @victoriacorbit.bsky.social and @ahmarilab.bsky.social! Lots of fond memories from running these experiments. The similarity in the behavioral and striatal neural response time course produced by driving M2 inputs was really striking.
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Jonas Wietek @jwietek.bsky.social · 30/01/2025
An early surge of norepinephrine along brainstem pathways drives sensory-evoked awakening www.biorxiv.org/content/10.1... Happy to see this great work (and some PdCO application) out in the wild.
The locus coeruleus norepinephrine (LC-NE) system regulates arousal and awakening; however, it remains unclear whether the LC does this in a global or circuit specific manner. We hypothesized that sensory-evoked awakenings are predominantly regulated by specific LC-NE efferent pathways. Anatomical, physiological, and functional modularities of LC-NE pathways involving the mouse basal forebrain (BF) and pontine reticular nucleus (PRN) were tested. We found partial anatomical segregation between the LC->PRN and LC->BF circuits. Extracellular NE dynamics in BF and PRN exhibited distinct sound-evoked activation during sleep, including a fast sound-evoked NE peak specific to PRN. Causal optogenetic interrogation of LC efferent pathways, by retro-ChR2 activation or PdCO silencing of synapses in target regions, revealed a pivotal role for early LC->PRN activity in driving arousal and sound-evoked awakenings. Together, our results uncover a prominent role for early LC-NE PRN activity in connecting sensory and arousal pathways and establish LC heterogeneity in regulating arousal.
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Bianca Jones Marlin, PhD @bjmarlin.bsky.social · 29/01/2025
Marlin Lab’s 1st Thesis Defense ✨ Hear the science @2:30pm EST bit.ly/MarlinLab Have the cheers @5:00 pm EST JLG✨ Columbia Biology student Beka Stecky will share her discoveries on “What the Nose, Knows” after learning an odor predicts a stressful experience.👃🏽🧬🧪
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Rachel Gatlin, PhD (she/her) @rachelgatlin5.bsky.social · 23/01/2025
My thesis defense date is official! And yes I put my cat and Tac2 neurons on my poster 🥰
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Dayu Lin @moccalin.bsky.social · 22/01/2025
Antipsychotics is often used to suppress hyper-aggression. Does it really suppress aggression or just cause sedation? Antipsychotics targets dopamine receptors. Our new study revealed that dopamine modulates aggression based on animals' fighting experience. www.nature.com/articles/s41...
nature.com
Experience-dependent dopamine modulation of male aggression - Nature
Dopaminergic neurons in the ventral tegmental area have a role in modulating aggression in adult male mice, and this effect of dopamine depends strongly on fighting experience.
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Richard Benton @bentonlab.bsky.social · 15/01/2025
Fly neuro people: has anyone tried the Ting lab’s scFLARE (or variants) for labelling active neurons in Drosophila? Thanks.
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Julieta Lis @julietalis.bsky.social · 16/01/2025
🚨Postdoc and Postbac positions available in my group at the NIEHS/NIH! Interested in investigating the neural mechanisms for social behaviors across development in a supportive environment? Make sure to apply! Job ads in🧵Feel free to DM/email w/ questions, please RT
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Björn Brembs @brembs.mastodon.social.ap.brid.gy · 07/01/2025
We are hiring! We are looking for two PhD students interested in the regulation of habit formation. Habits are useful to decrease cognitive load, but carry the risk of becoming stereotyped and hard to control - it’s hard to shake a bad habit. The fruit fly Drosophila also forms habits and we […]
mastodon.social
Original post on mastodon.social
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Reposted by Eyal Rozenfeld
Annegret Falkner @neurrriot.bsky.social · 02/01/2025
New year new work from the lab! We explore whether aggression experience and observation lead to similar changes in future aggression strategy. (They do!) We perform 2-color imaging across the whole social behavior network across time and track changes www.biorxiv.org/content/10.1...
biorxiv.org
Aggression experience and observation promote shared behavioral and neural changes
The ability to observe the social behavior of others and use observed information to bias future action is a fundamental building block of social cognition. A foundational question is whether social o...
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Yulong Li Lab @yulonglilab.bsky.social · 28/12/2024
(1/6) Excited to introduce our first generation red acetylcholine sensors! #acetylcholine #GRAB #RedSensors www.biorxiv.org/content/10.1...
biorxiv.org
Red-shifted GRAB acetylcholine sensors for multiplex imaging in vivo
The neurotransmitter acetylcholine (ACh) is essential in both the central and peripheral nervous systems. Recent studies highlight the significance of interactions between ACh and various neuromodulat...
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Masseck Lab @massecklab.bsky.social · 18/12/2024
🎄PinkyCaMP- our christmas gift to you! 🎁: We are excited to present PinkyCaMP, the first mScarlet based calcium sensor with: ✨exceptional, brightness ✨phototability ✨and optogenetic compatability. Check out our new preprint: www.biorxiv.org/content/10.1...
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Timothy O'Leary @timothyoleary.bsky.social · 17/12/2024
Apropos of never ending discussions about whether ANNs are "good" models of the nervous system, here is a slide I present to masters students showing a network that is found in motor control circuits *across phyla* (that's pretty ubiquitous!) I ask them to guess what it does...
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Johannes Felsenberg @felsenberg.bsky.social · 16/12/2024
Why not joining us?
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Jonas Wietek @jwietek.bsky.social · 16/12/2024
Wanna switch on/off synaptic transmission but not the ideal vector for your🧠🧪🔬, we are happy to help! Requested recently & available to you: ChrimsonR(no soma targeting)+PdCO (Cre & non-Cre) DoxOn/OFF PdCO-EGFP (TREtight) -> docs.google.com/spreadsheets... Probably soon @addgene.bsky.social too.
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Carolina Rezaval @crezaval.bsky.social · 15/11/2024
Sex or survival—what’s more important? Excited to share our @Nature paper on how flies resolve this conflict. We found a dopamine-based filter that reduces threat perception, helping flies focus on courtship when close to mating. www.nature.com/articles/s41...
nature.com
Mating proximity blinds threat perception - Nature
A state-dependent dopamine filter system in the male Drosophila brain balances threat perception against the drive to mate.
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Daniela Duarte Domingues @neurodaniela.bsky.social · 15/12/2024
Hi everyone! I am Daniela, a pre-clinical psychedelic researcher doing a PhD at the Paris Brain Institute under the supervision of Eric Burguière. I am working with the SAPAP3-KO mice and LSD. I am a great advocate for open science, diversity and science communication! Nice to meet you all 🥰
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Luke Sjulson @lukesjulson.bsky.social · 13/12/2024
Neuroscience students asked us to teach a PRACTICAL course on experimental methods, and it is now on YouTube! Please like and repost to help us get the word out! www.youtube.com/playlist?lis... Lecture 1: Signals and data acquisition Focusing on hardware, digital/analog I/O, synchronization 🧵
youtube.com
Neuroscience methods - YouTube
Nanocourse: Approaches to Study Neural Circuits This course was taught by Anita Autry, Tiago Gonçalves, and Luke Sjulson at Albert Einstein College of Medici...
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Lena Riabinina @lenariab.bsky.social · 01/12/2024
I made the Insect Sensory Neuro starter pack - let me know in the comments if you'd like to be added! (and also I'm sure I missed tons of people - tag them in!) go.bsky.app/JW7c5LN
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Catherine (Katie) Schretter @ceschretter.bsky.social · 12/12/2024
Excited to have this paper out (rdcu.be/d0T3Y)! In it, we focused on how flies know what to attend to in a complex environment (like below)? We uncovered neuronal pathways through which social states (like aggression 🥊) modulate visual processing in #Drosophila. #WomenInSTEM #neuroscience 🧪 1/
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Adithya Rajagopalan @adiraj95.bsky.social · 12/12/2024
It was nice to take a break from project-related OFC/amygdala papers & read a fun fly study from the Parnas lab this morning: www.science.org/doi/full/10.... Exciting to see potentially distinct pathways for cue- & action- outcome learning in the fly, drawing parallels between the MB & striatum.
science.org
Neuronal circuit mechanisms of competitive interaction between action-based and coincidence learning
Parallel and interfering neuronal circuits are responsible for operant and classical learning.
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Luke Sjulson @lukesjulson.bsky.social · 10/12/2024
Everyone knows that failure is bad. We devote a lot of time to trying to avoid it. But sometimes failure is good. A brief story: ~11 yrs ago, when my friends were all starting their own labs, I was starting my 2nd postdoc. My 1st postdoc (w/ Gord Fishell at NYU) had ended in disaster when 1/
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Eyal Rozenfeld @eyalrozenfeld.bsky.social · 08/12/2024
1/ 🧠 Ever wondered how different types of learning coexist in our brains? Spoiler: Sometimes, they don’t! Our new study flips the script on what we thought about memory and learning in Drosophila. Dive in for a surprising twist! 🧵👇 www.science.org/doi/10.1126/...
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mosheparnas.bsky.social @mosheparnas.bsky.social · 08/12/2024
1/ How do animals integrate different forms of learning? Our @eyalrozenfeld.bsky.social new study in Science Advances shows that active mechanisms prevent the co-formation of competing memories. Here’s what we found! 🧵👇 science.org/doi/10.1126/...
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Simon Sprecher @simon-sprecher.bsky.social · 08/12/2024
Very cool work: interfere between classic and operant conditioning!
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Eyal Rozenfeld @eyalrozenfeld.bsky.social · 08/12/2024
1/ 🧠 Ever wondered how different types of learning coexist in our brains? Spoiler: Sometimes, they don’t! Our new study flips the script on what we thought about memory and learning in Drosophila. Dive in for a surprising twist! 🧵👇 www.science.org/doi/10.1126/...
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Katrin Vogt @katrinvogt.bsky.social · 07/12/2024
This exciting new paper about the neural mechanisms underlying classical and operant learning in flies 🪰 is finally out - it matters which paradigm you use to test your animals!
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Carolina Rezaval @crezaval.bsky.social · 06/12/2024
New from Shiko Parnas' lab: Classical & operant learning in *Drosophila* rely on distinct neuronal pathways, challenging current paradigms! Unstoppable www.science.org/doi/10.1126/...
science.org
Neuronal circuit mechanisms of competitive interaction between action-based and coincidence learning
Parallel and interfering neuronal circuits are responsible for operant and classical learning.
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Annegret Falkner @neurrriot.bsky.social · 05/12/2024
Thanks Stories of Win! It felt really great to be able to gush about the lab and the people who have made it so awesome. 😊
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Stories of WiN @storiesofwin.bsky.social · 05/12/2024
Check out our latest profile! Dr. Annegret Falkner (@neurrriot.bsky.social) studies how social experiences and internal states shape behavior. To learn more & listen to the full interview, follow the link below! www.storiesofwin.org/profiles/202... #StoriesOfWiN #WomenInNeuroscience #WomenInNeuro
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Eyal Rozenfeld @eyalrozenfeld.bsky.social · 05/12/2024
Every intro to neuroscience textbook features voltage gated sodium channels, but did you know that #GPCRs are also voltage dependent? In our @natureportfolio.bsky.social paper we found that GPCR voltage dependency controls neuronal plasticity and behavior. www.nature.com/articles/s41...
nature.com
GPCR voltage dependence controls neuronal plasticity and behavior - Nature Communications
G-protein coupled receptors are regulated by the membrane potential in vitro. Here, the authors show that muscarinic receptor voltage independence causes a strong behavioural effect of increased odour...
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Ann Clemens @annmclemens.bsky.social · 05/12/2024
In our paper @currentbiology.bsky.social we uncover the tactile & afferent mechanisms of the rat pup transport response. Teamwork ✋ Zheyi, Connor, Arturo, Marta, Yu, Michael @sidb-edinburgh.bsky.social @edinunineuro.bsky.social @mblscience.bsky.social Read the dispatch too! tinyurl.com/4ez3k9uw
cell.com
Tactile mechanisms and afferents underlying the rat pup transport response
Ni et al. uncover mechanisms underlying rat pup transport response (TR). Anterior neck grasp, 4-Hz shake, and translation promote TR; reversal occurs with ground simulation. Anterior neck sensory endings labeled after TR; neck cortex thins in development. Mechano-sensory neck skin afferents may specialize for offspring-maternal cooperative transport.
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Alice Ting @aliceyting.bsky.social · 04/12/2024
Could one envision a synthetic receptor technology that is fully programmable, able to detect diverse extracellular antigens – both soluble and cell-attached – and convert that recognition into a wide range of intracellular responses, from gene expression and real-time fluorescence to modulation..
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Jonas Wietek @jwietek.bsky.social · 03/12/2024
here are only 38 patch-clampers on this plattform!?! Who else? 🧠 🔬 🧪 go.bsky.app/RuCRCgX
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Ofer Yizhar @oyiz.bsky.social · 28/11/2024
Many people have asked me what's the deal with "SIO" in our Addgene vectors (www.addgene.org/Ofer_Yizhar/) - we use these in most of our Cre-dependent AAVs - so here's a brief explanation of how it works.
addgene.org
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Carolina Rezaval @crezaval.bsky.social · 26/11/2024
Flies raised in isolation develop fear of their peers, but exposure to others helps them regain sociability. Cool research from the Ramdya Lab! www.biorxiv.org/content/10.1....
biorxiv.org
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Nikolas Karalis @nikolaskaralis.bsky.social · 17/11/2024
How to rebuild your network on @bsky.app and improve your experience here? I made a short starter guide with resources. www.neuronaldynamics.eu/resources/bl... Also, a thread 🧵 below.
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