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Sean Piantadosi

@piantadosisean.bsky.social
325 followers 308 following 9 posts

Post-doctoral fellow in the Bruchas lab at the University of Washington.

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Reposted by Sean Piantadosi
Tallie Z Baram @talliezee.bsky.social · 01/12/2025
🙏 @sfnjournals.bsky.social now out! & while celltype &ephys are alike across sexes, behavioral functions and axon terminal distribution in NAc and brainwide diverge by sex and #stress. @ladenardo.bsky.social
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Matt Hill @cannabrain.bsky.social · 25/11/2025
New lab paper drop, this one has been a long time coming! Driven by Rob Aukema (now a postdoc with Kerry Ressler) this paper in Science Advances answered the lingering question of what role the amygdala plays in stress-induced neuroendocrine responses. www.science.org/doi/10.1126/...
science.org
A network of basolateral amygdala projection neurons contributes to stress-induced activation of the hypothalamic-pituitary-adrenal axis
A network of basolateral amygdala neurons, but not singular projections, contributes to the neuroendocrine response to stress.
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Jeremy Day @daylab.bsky.social · 26/11/2025
New computational paper from the lab! Thanks to the reviewers for helping us improve this paper from the preprint version and Nucleic Acids Research for a smooth publication process.
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Ben Saunders @bensaunders.bsky.social · 24/11/2025
So excited to see our latest paper out today in @natcomms.nature.com! Studies led by the amazing @margestelzner.bsky.social www.nature.com/articles/s41.... VTA GABA neurons have a unique role in economic decision making - they integrate reward seeking motivation and the current cost of seeking
nature.com
Ventral tegmental area GABA neurons integrate positive and negative valence - Nature Communications
The role of ventral tegmental area GABA neurons in behavior is unclear. Here, authors show that VTA GABA but not dopamine neurons integrate positive and negative valence to encode motivational conflic...
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Sean Piantadosi @piantadosisean.bsky.social · 09/10/2025
cool new work from @ppiantad.bsky.social and the Holmes laboratory looking at how BLA neurons encode risk using a variety of approaches. check it out!
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John Tuthill @tuthill.bsky.social · 07/04/2025
UW folks, don't miss @ishmailsaboor.bsky.social's seminar tomorrow.
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Tom Kash @superkash.bsky.social · 07/04/2025
Our work, lead by former graduate student Olivia Hon on the BNST, CRF and regulation of different types of fear is finalized as an elife reviewed preprint. elifesciences.org/reviewed-pre...
elifesciences.org
Sex Differences in BNST Signaling and BNST CRF in Fear Processing: Implications for Unpredictable Threat in Sustained Fear
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Chris Zimmerman @czimmerman.bsky.social · 03/04/2025
How do we associate the flavors we experience during a meal 🍽️😋 with postingestive effects like food poisoning 🤢🤮 that arise much later? Our answer in @nature.com this week: Illness signals from the gut reactivate and strengthen flavor representations in the amygdala. 📄: nature.com/articles/s41...
nature.com
A neural mechanism for learning from delayed postingestive feedback - Nature
Illness signals from the gut reactivate and strengthen flavour representations in the amygdala to support learning from delayed postingestive feedback.
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Alex Kwan @alexkwan.bsky.social · 02/04/2025
Our latest study identifies a specific cell type and receptor essential for psilocybin’s long-lasting neural and behavioral effects 🍄🔬🧠🧪 Led by Ling-Xiao Shao and @ItsClaraLiao Funded by @NIH @NIMHgov 📄 Read in @nature.com - www.nature.com/articles/s41... 1/12
nature.com
Psilocybin’s lasting action requires pyramidal cell types and 5-HT2A receptors - Nature
A pyramidal cell type and the 5-HT2A receptor in the medial frontal cortex have essential roles in psilocybin’s long-term drug action.
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Kaixin (Catherine) Huang @kxhuang.bsky.social · 12/03/2025
Thrilled to share our latest work🚀! Interested in corticostriatal circuits and genetics of anorexia nervosa? Check out our preprint on bioRxiv! www.biorxiv.org/content/10.1...
biorxiv.org
A genetic signature of resistance to activity-based anorexia in striatal projecting cortical neurons
Anorexia nervosa (AN) is a complex psychiatric disorder characterised by severe pathological weight loss and persistent cognitive inflexibility. Converging evidence from neuroimaging studies and genom...
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Susanne Ahmari @ahmarilab.bsky.social · 14/02/2025
🚨Amidst all the uncertainty at NIH Welcome Leap just launched an important new $50M program in Women’s Health👩🏻‍🔬🧠 CARE focuses on the link between Alzheimer’s and perimenopausal hormonal changes wellcomeleap.org/care/ Note: full indirects! Please share widely to support women’s health 🙏🏼
wellcomeleap.org
CARE Program Details | Wellcome Leap: Unconventional Projects. Funded at Scale.
NEW $50M Program in Women's Health care Cutting Alzheimer's Risk through EndocrinologyWe are pleased to announce the selected performers.Sabine Vollstädt-Klein, Central Institute of Mental Health ...
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Susanne Ahmari @ahmarilab.bsky.social · 31/01/2025
Feels odd to post in a normal way about science right now, but I am REALLY proud of this work from the amazing @victoriacorbit.bsky.social from her grad student days in my lab 💪🧠💗 Huge congrats to her, @piantadosisean.bsky.social, & the whole team on this tour-de-force!🎊🎊🎊 Bluetorial on the way...
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bioRxiv Neuroscience @biorxiv-neursci.bsky.social · 01/02/2025
The NIH BRAIN Initiatives Impacts in Systems and Computational Neuroscience, 2014-2023 www.biorxiv.org/content/10.1101/202…
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Victoria Corbit, PhD @victoriacorbit.bsky.social · 31/01/2025
FYI @ahmarilab.bsky.social is still following up on this work if any trainees are interested 👀 Great opportunity to study behavior relevant for OCD🐀🧠 use cutting edge techniques🔬🧬 and have a supportive and encouraging mentor 🫶 Not to mention, Pittsburgh is the best 💛🖤
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Sean Piantadosi @piantadosisean.bsky.social · 31/01/2025
So happy to see this paper out! Congrats @victoriacorbit.bsky.social and @ahmarilab.bsky.social! Lots of fond memories from running these experiments. The similarity in the behavioral and striatal neural response time course produced by driving M2 inputs was really striking.
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Mel Sharpe @melissajsharpe.bsky.social · 29/01/2025
Folks at #wcbr- Come check out our symposium on lateral hypothalamus and addiction tomorrow (Wed), 4:30pm in Alpine B. Organised by @marcusweera.bsky.social! I’ll be presenting on #dopamine in lateral hypothalamus and how this changes after methamphetamine self-admin! 🧠 🧪 🧬
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Susanne Ahmari @ahmarilab.bsky.social · 28/01/2025
NIH memo addresses ‘confusion’ about restrictions imposed by Trump, easing some concerns | Science | AAAS www.science.org/content/arti...
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Phil Corlett @philcorlett.bsky.social · 27/01/2025
Early start (7:30am symposium) in Grand Ballroom C, for WinterBrain ❄️🧠 I’ll be talking about translational approaches to paranoia, and consilience across rodents, primates, and humans
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Daniela Duarte Domingues @neurodaniela.bsky.social · 20/01/2025
Registrations are open for the 2nd "Beginners training school on the use of home-cage technologies to monitor rodents". If you are working or interested in working in animal behaviour using home-cage systems, you need to sign up! All costs covered! 17-20 June Bratislava buff.ly/3E7MiaW
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Phil Corlett @philcorlett.bsky.social · 14/01/2025
@kurtfraser.bsky.social and I just had our paper on dopamine, salience, and psychosis accepted @ Am J Psychiatry. We review the history of aberrant salience and the data gathered since: osf.io/preprints/ps...
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Sean Piantadosi @piantadosisean.bsky.social · 14/01/2025
Be sure to check out new Bruchas lab work from @davidjmarcus.bsky.social and co-authors! An exciting and nuanced story unraveling how endocannabinoid signaling influences behavioral engagement. Make sure to dive into the Supplemental Figures which describes the circuit's role in aversive behavior.
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Paul Frankland @franklandlab.bsky.social · 10/01/2025
A reminder about our position at SickKids/U of T. Accepting applications until February 15th. Please share widely. can-acn.org/scientist-se...
can-acn.org
Scientist/Senior Scientist – Research Institute, Hospital for Sick Children, University of Toronto – Canadian Association for Neuroscience
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Sean Piantadosi @piantadosisean.bsky.social · 19/12/2024
Very excited for this! Abstract submission is open now and the due date is Februrary 14th, 2025!
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Masseck Lab @massecklab.bsky.social · 18/12/2024
🎄PinkyCaMP- our christmas gift to you! 🎁: We are excited to present PinkyCaMP, the first mScarlet based calcium sensor with: ✨exceptional, brightness ✨phototability ✨and optogenetic compatability. Check out our new preprint: www.biorxiv.org/content/10.1...
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davidweinshenker.bsky.social @davidweinshenker.bsky.social · 11/12/2024
Saving the best for last! If you are still at #ACNP2024 stop by grad student Abby Galvez's poster (W48) describing mesolimbic dopamine dysfunction in a selectively bred rat model of bipolar disorder.
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Sean Piantadosi @piantadosisean.bsky.social · 11/12/2024
If you are still at #ACNP2024 and are interested in the locus coeruleus and/or the amygdala, please stop by my poster from the @mbruchas lab examining how both nodes of this circuit mediate stress-induced anxiety-like behavior tonight (W169)!
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Paul Frankland @franklandlab.bsky.social · 11/12/2024
Coming soon: We have a Scientist position in the Neuroscience & Mental Health Program at SickKids. Should post details later this week. Stay tuned.
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Sarah Stern @sarahstern.bsky.social · 11/12/2024
If you’re still hanging around at #ACNP2024 tonight and you’re interested in the insular cortex, interoception, food intake or single-cell seq, stop by my poster (170)!
media.tenor.com
a girl wearing sunglasses with the words see you there on the bottom
ALT: a girl wearing sunglasses with the words see you there on the bottom
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Brain in a Jar @braininajar.bsky.social · 09/12/2024
Hello #ACNP2024 I’m Kasey Girven a Postdoc in the Bruchas Lab at The University of Washington. I study how a neuropeptide S, peri-coerulear projection to the OFC is recruited during repeat exposure to high value rewards 🐭🧀💉 Come listen to my spiel this Wednesday at 3PM in the Grand Sonoran JK 🧠
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Raaj Gowrishankar @outraajeous.bsky.social · 09/12/2024
Hi #ACNP2024! I'm a NIDA K99 postdoc in Michael Bruchas' lab at UW, interested in how endogenous opioids in the basal ganglia promote goal-directed behavior. Come by my poster on Wed (W171) if you'd like to hear more. I'm also on the job market and would love to chat about potential opportunities!
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Jeremy Day @daylab.bsky.social · 08/12/2024
Hey #ACNP2024 attendees, UAB Neurobiology is looking to recruit 4 faculty in the areas of addiction neuroscience, iPSC/organoids, and neurodevelopmental disorders. All searches are open rank. Specific ads are forthcoming, but you can also apply at this link! uab.peopleadmin.com/postings/18636
uab.peopleadmin.com
School of Medicine - Open Rank Neurosciences Strategic Hire
The University of Alabama at Birmingham* (UAB) Heersink School of Medicine (HSOM)** is recruiting up to 20 investigators as part of a major strategic initiative in the Neurosciences to build on a stro...
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Ben Saunders @bensaunders.bsky.social · 08/12/2024
Sad to miss #ACNP2024 but check out our new studies by the amazing @margestelzner.bsky.social - comparing dopamine vs GABA neurons in the VTA in different forms of learning - our results support an overall re-evaluation of midbrain representation of valence and appetitive motivation (thread)
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Susanne Ahmari @ahmarilab.bsky.social · 08/12/2024
Acting NIMH Director Shelli Avenevoli, Ph.D. kicking off NIMH section of #ACNP2024 Directors Panel by highlighting job search for permanent NIMH Director- deadline extended to Feb 28, 2025 👀 hr.nih.gov/jobs/search/...
hr.nih.gov
Director, National Institute of Mental Health
The National Institutes of Health (NIH), the world’s premier biomedical research institution, is seeking applications from exceptional candidates for the exciting position of Director, National Instit...
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Eyal Rozenfeld @eyalrozenfeld.bsky.social · 08/12/2024
1/ 🧠 Ever wondered how different types of learning coexist in our brains? Spoiler: Sometimes, they don’t! Our new study flips the script on what we thought about memory and learning in Drosophila. Dive in for a surprising twist! 🧵👇 www.science.org/doi/10.1126/...
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Keri Martinowich @martinowk.bsky.social · 07/12/2024
Lateral septum is really important for many behaviors relevant to neuropsychiatric disorders - and just super cool! Check out our LS panel, co-chaired by me and @ewhizabeth.bsky.social and w/ @superkash.bsky.social and Corey Harwell Wed AM. Image of LS in human 🧠 - details in Alt text #ACNP2024
Immunofluorescence staining of human lateral septum brain tissue. Magenta marking TRPC4 expression - marker of lateral septal neurons.
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Daniel Castro @flanbrain.bsky.social · 07/12/2024
Headed to @acnporg.bsky.social come see our panel on opioids and depression Monday morning, and DEFINITELY stop by our lab’s postdoc @katybraden.bsky.social poster to learn more!! 🤩🤩💃🏻💃🏻👯‍♂️👯‍♂️👯‍♂️
media.tenor.com
a woman wearing glasses and a black top says you have a lot to learn
ALT: a woman wearing glasses and a black top says you have a lot to learn
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Tom Kash @superkash.bsky.social · 04/12/2024
write up about new cluster hire: research.unc.edu/2024/12/04/c...
research.unc.edu
Carolina cluster hire program will strengthen substance use disorder research - UNC Research
As a strategy of the Research Roadmap, Carolina is hiring up to four researchers to build a new cross-disciplinary team that expands the University’s capacity to develop resources for our communities.
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Ofer Yizhar @oyiz.bsky.social · 28/11/2024
Many people have asked me what's the deal with "SIO" in our Addgene vectors (www.addgene.org/Ofer_Yizhar/) - we use these in most of our Cre-dependent AAVs - so here's a brief explanation of how it works.
addgene.org
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