iiinova — where your digital self keeps evolving

Rainero lab @erainerolab.bsky.social · 30/01/2026

Latest addition to our Wall of Fame!! Ifeoluwa Oyelade @mcb-sheffield.bsky.social

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mcb-sheffield.bsky.social @mcb-sheffield.bsky.social · 30/01/2026

Join us in Sheffield! We are keen to support early career researchers in applying for independent research fellowships to join our friendly & collaborative environment, in areas related to gene expression, mechanistic cell biology & cancer biology. For more info 👇 sheffield.ac.uk/biosciences/...

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Rainero lab @erainerolab.bsky.social · 22/10/2025

Fantastic presentation by Ife at the Sheffield Pancreatic Cancer Network!! @mcb-sheffield.bsky.social

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mcb-sheffield.bsky.social @mcb-sheffield.bsky.social · 08/10/2025

We are delighted to host Harsha Kantamneni today from the University of Bradford. "Endosomal Sorting Complex Required for Transport (ESCRT): Roles in receptor trafficking, signalling pathways, drug resistance and disease" 📍 Alfred Denny Conference Room 📅 18th October - 1pm

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Rainero lab @erainerolab.bsky.social · 30/09/2025

Congratulations to Shahd on passing her PhD viva!!!! Thanks to Christoph and Jason @jasonkinglab.bsky.social for examining

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Rainero lab @erainerolab.bsky.social · 17/09/2025

Great talk by our own Zhe Bao at the School of Biosciences 3rd year PGR symposium!! @mcb-sheffield.bsky.social

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Rainero lab @erainerolab.bsky.social · 16/09/2025

#NPAW2025 #PostdocAppreciationWeek Mona is a @cancerresearchuk.org funded postdoc in our lab. She demonstrated that the #ECMatrix supports breast cancer cell growth under starvation by promoting tyrosine catabolism. You can read more about this here: 👇 pubmed.ncbi.nlm.nih.gov/38227562/

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Rainero lab @erainerolab.bsky.social · 01/09/2025

Our own Ife will present her PhD work!!

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bioRxiv Cancer Bio @biorxiv-cancer.bsky.social · 01/09/2025

SMART: A Spatio-Molecular Atlas of Response Trajectories in Triple-Negative Breast Cancer www.biorxiv.org/content/10.1101/202…

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Saez-Rodriguez Group @saezlab.bsky.social · 25/08/2025

We present our MetaProViz #Rpackage for #metabolomics analysis & prior knowledge integration to generate mechanistic hypotheses on how metabolic changes affect metabolite classes, pathways & environment interaction 🔗 www.biorxiv.org/content/10.1... 📦 saezlab.github.io/MetaProViz/ 🧵 Thread ⬇️

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Rainero lab @erainerolab.bsky.social · 03/07/2025

On my way to #CRUKAllFellows meeting. Looking forward to it!

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Alex Gould Lab @alexgouldlab.bsky.social · 01/07/2025

Calling all meeting organizers… @biologists.bsky.social now have a calculator to estimate your event’s carbon footprint and to test various reduction scenarios. thenode.biologists.com/event-carbon...

thenode.biologists.com

Event carbon calculator - the Node

I am excited to announce the release of our event carbon calculator, our latest resource to support the creation of sustainable events. Estimate your

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Rainero lab @erainerolab.bsky.social · 01/07/2025

Welcome to the lab Fatmagul!! Joining the lab summer walk is a great way to start! @mcb-sheffield.bsky.social

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Rainero lab @erainerolab.bsky.social · 01/07/2025

Fantastic lab walk with @helenkmatthews.bsky.social ! Thanks to Bian, Rachele and @vichart33.bsky.social for organising

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Derivery Lab - MRC LMB @deriverylab.bsky.social · 23/06/2025

🚨 JOB ALERT 🚨 We're hiring a Research Assistant – no PhD needed! Join us to explore the molecular mechanisms of receptor sorting in endosomes. Experience in protein expression/purification, cloning & cell culture desired 🧫🔬 Apply now 👉 www.nature.com/naturecareer... #STEMCareers #ResearchJobs

A picture of 3 rows of people on steps at the MRC LMB. From left to right - top row: Akaash, Vic, Lara - Middle row: Kerrie, Manu, Paddy - bottom row: Meg and Julie

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Victoria Hart @vichart33.bsky.social · 23/06/2025

I am excited to share our new Sheffield Pancreatic Cancer Research Network website! Please check it out at... sites.google.com/sheffield.ac... @fohsheffield.bsky.social @mcb-sheffield.bsky.social

sites.google.com

Sheffield Pancreatic Cancer Research Network

Meet the Team

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mcb-sheffield.bsky.social @mcb-sheffield.bsky.social · 18/06/2025

We are delighted to host @cassiejclarke.bsky.social today from the @cruk-si.bsky.social! "Neutrophil metabolism supports metastasis of mammary cancer by altering immune and extracellular matrix landscapes" 📍 Alfred Denny Conference Room 📅 10th June - 1pm

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Manuela Casasoli @manuelacasasoli.bsky.social · 09/06/2025

Extracellular matrix plays an important role in #cancer. "Understanding spatial matrix heterogeneity and its interactions with immune cells is critical for improving immunotherapy responses in matrix-rich cancers, such as pancreatic cancer." 🧪🧬 #Science #Biology #Health www.cell.com/trends/cance...

Image Source:
https://www.cell.com/trends/cancer/fulltext/S2405-8033(25)00126-8

Figure 1 Key anti- and protumour functions of the extracellular matrix (ECM).

Antitumour functions are shown in green and protumour functions are shown in red.

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Rainero lab @erainerolab.bsky.social · 12/06/2025

Exciting opportunity to join the cancer research community in Sheffield!!

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Cassie Clarke @cassiejclarke.bsky.social · 09/06/2025

Delighted to share the work of @gounismichalis.bsky.social describing how metabolic reprogramming of micrometastatic cells influences EV release to generate invasive microenvironments.Michalis is an immense talent & it really is an honour to share his PhD work & my first senior author paper #ProudPI

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Chris Tape @christophertape.bsky.social · 10/06/2025

2 weeks left to apply for our new fully funded postdoc position studying plasticity regulators in metastatic CRC!

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Leonardo Almeida-Souza @leonardoasouza.bsky.social · 09/06/2025

🧵1/6 — Preprint Alert! I am super proud to present the latest work of our lab. Earthlings and those just visiting, I introduce you…. EndoNB: A better, smarter and versatile way to study the dynamics of cell surface proteins. 🧪 www.biorxiv.org/content/10.1...

biorxiv.org

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Rainero lab @erainerolab.bsky.social · 05/06/2025

Congratulations Bian on passing you PhD viva!!! Thanks to @zech-lab.bsky.social, @helenkmatthews.bsky.social and John for examining @mcb-sheffield.bsky.social

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mcb-sheffield.bsky.social @mcb-sheffield.bsky.social · 04/06/2025

We are delighted to host @vickysanzmoreno.bsky.social today from the @icr.ac.uk! "Biomechanical hallmarks and vulnerabilities of metastatic cancer cells" 📍 Alfred Denny Conference Room 📅 4th June - 1pm @insigneoinstitute.bsky.social @sheffielduni.bsky.social @sheffielduni.bsky.social

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InFLAMES Research Flagship @inflames-flagship.bsky.social · 03/06/2025

In a new study led by InFLAMES PI Professor Johanna Ivaska and Dr James Conway have developed a new fluorescent probe to visualise signaling dynamics in moving cancer cells which they used to uncover a new therapeutic possibility for limiting breast cancer spread. #Illusia @ivaskalab.bsky.social

inflames.utu.fi

New visualisation tool helps researchers to target breast cancer dissemination - InFLAMES Research Flagship

Cancer cell movement during metastasis is a dynamic process regulated by several different signals. However, the way cells receive, process and respond to these signals has been extremely hard to dete...

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Rainero lab @erainerolab.bsky.social · 23/05/2025

Totally agree!! It was an amazing meeting

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Rainero lab @erainerolab.bsky.social · 22/05/2025

Amazing talk by Ife at the @mcb-sheffield.bsky.social 2nd year PGR symposium

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mcb-sheffield.bsky.social @mcb-sheffield.bsky.social · 22/05/2025

📣 New paper alert! The El-khamisy lab uncovered how a key protein, NuMA, helps repair damaged DNA and protect important control regions of our genome, especially after oxidative stress. 🛡️ Protecting the genome = protecting health. www.cell.com/cell-reports...

cell.com

ADP-ribosylation of NuMA promotes DNA single-strand break repair and transcription

Abugable et al. investigated the role of ADP-ribosylation in NuMA function during DNA repair. They demonstrate that ADP-ribosylation-deficient NuMA impairs repair kinetics and transcription and fails ...

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Guillaume Jacquemet @guijacquemet.bsky.social · 19/05/2025

I cannot wait for this meeting, it's going to be awesome

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Rainero lab @erainerolab.bsky.social · 16/05/2025

Congratulations to Rachele for passing her PhD viva!!! Well done!!! Thanks to Bian for the amazing cake

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