Team REWIRE-CAN, led by Professor Bart Vanhaesebroeck of the UCL Cancer Institute, will receive up to $25m over approximately five years to take on the rewiring cancer cells challenge.

The Pre-Cancer Immunology Lab (James Reading Lab) is mapping pre-invasive T cell dynamics during carcinogenesis to detect and intercept cancer development.

The 2nd European Cancer Dependency Map Symposium is a scientific event open to the national and international scientific community working in computational genomics, pharmacogenomics, and therapeutic ...

Using organoids, researchers have found that 'revival' stem cells could hold the key to why people's cancers respond differently to treatment

Using organoids, researchers have found that 'revival' stem cells could hold the key to why people's cancers respond differently to treatment

The CRC-STARS team will learn more about how bowel cancer behaves so that it can potentially be treated in a more personalised way

Salary for this Role: From £39,950 per annum with benefits, subject to skills and experience Job Title: Senior Laboratory Research Scientist Reports to: Fabian Frohlich Closing Date: 13/Apr/2025 23.59...

Cellular phenotypes are regulated by dynamic signalling processes that involve proteins, post-translational modifications, epigenetic events, and tran…

The dictum “Everything should be made as simple as possible, but no simpler” poses a problem for biology. How simply can it be told without doing damage to its complex nature? The answer might be foun...

Oncofetal (OnF) reprogramming, driven by YAP and AP-1, induces phenotypic plasticity and therapy resistance in WNT-dependent colorectal cancer (CRC). Targeting the OnF state in combination with chemot...

Positive research cultures provide the environment for scientists to explore ideas, grow as individuals, develop team science and create a positive impact on those around them. Here we focus on key a...

This work presents a graph signal processing method, gene signal pattern analysis, to embed gene signals from single-cell sequencing data. In diverse experimental set-ups and case studies, GSPA establ...

imageimageA single-cell signaling framework is developed for quantitative measurements of information flow within the phosphoinositide 3-kinase (PI3K) pathway, enabling high-resolution studies of grow...

A new chimeric antigen receptor T cell (CAR-T) therapy has delivered promising results in treating patients with an aggressive blood cancer, in results from a clinical trial led by researchers at UCL ...