The move came after the NIH director refused Trump’s request to cut Harvard grants in an Oval Office meeting.

Up to 20% of that crowd drives in from Ontario, and a few tough guys still got hurt by a 90 second song.

He showed that specialized cells retain the genes to form an organism.

In vivo loss-of-function CRISPR screens were performed to identify genes influencing CAR T cell persistence and function in human multiple myeloma, highlighting CDKN1B as a promising target.

Bridge recombinases are naturally occurring RNA-guided DNA recombinases that we previously demonstrated can programmably insert, excise, and invert DNA in vitro and in Escherichia coli. In this study,...

The switch between proliferation and invasion is triggered by mechanical force.

G-quadruplexes (G4s) are prevalent DNA structures that regulate transcription but also threaten genome stability. How G4 dynamics are controlled remains poorly understood. Here, we report that RNA tra...

The discovery that DNA methylation of different CpG sites can serve as digital barcodes of clonal identity led to the development of EPI-Clone, an algorithm that enables single-cell lineage tracing th...

Jordan’s beautiful and gentle soul was tragically taken from his family, … Heather La Forme needs your support for Honor Jordan: Support for funeral expenses.

On March 7, 2025, we rally to defend science as a public good and pillar of social, political, and economic progress.

The Trump administration hobbles research and endangers the public health.

Expression of the transporter SLC43A2 by tumour cells allows them to outcompete T cells for methionine and thereby disrupt the survival and function of tumour-infiltrating T cells.

The intrinsically disordered protein α-synuclein plays a key role in the pathogenesis of Parkinson's disease (PD). We show here that the native state of α-synuclein consists of a broad distribution of...

A spatially resolved single-cell transcriptomics map of the mouse brain at different ages reveals signatures of ageing, rejuvenation and disease, including ageing effects associated with T cells and r...