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Dr Neil Stone

@drneilstone.bsky.social
13K followers 4.8K following 394 posts

Infectious Diseases specialist doctor in London. Fungal disease researcher (UCL). Officially the 1st person to use word #Covid (according to the Oxford English Dictionary. Really). Personal views only.

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Reposted by Dr Neil Stone
Mycoses Study Group Education & Research Consortium @msgerc.bsky.social · 07/05/2026
15th May deadline for abstracts for the biennial meeting of the MSGERC in Denver, Colorado in September! Get your abstracts in!
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Mycoses Study Group Education & Research Consortium @msgerc.bsky.social · 25/04/2026
For those interested in mycology clinical trials Sign up to this online event! msgerc.wildapricot.org/event-6653782
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Dr Neil Stone @drneilstone.bsky.social · 21/04/2026
Well that's a wrap for #escmidglobal2026 in Munich The annual ID /Microbiology "mega conference" has been a roaring success once again. See you all next time in Stockholm, Sweden 🇸🇪 for #escmidglobal2027!!
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Dr Neil Stone @drneilstone.bsky.social · 21/04/2026
The single most important thing in a scientific presentation is clarity. A good presentation is a clear presentation.
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Prof Jenny Rohn @jennyrohn.bsky.social · 21/04/2026
Jazmin Díaz-Regañón presenting interesting post-hoc analysis of Phase 3b trial of gepotidacin - looked at baseline rUTI, older age & more severe baseline symptoms. Endpoints included CSI/CSR. Concluded this antibiotic could work in harder-to-treat #UTI subgroups. #ESCMIDGlobal2026 #UTISky
Poster presented on a screen with a speaker
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Ursula Hofer @hoferu.bsky.social · 21/04/2026
#ESCMIDGlobal2026 has been fabulous -- it's been such a treat to meet authors, students, friends etc. Thank you so much for all the lovely and constructive feedback about the journal and Lancet in general. My favourite probably was "it was great when you rejected me, the comments were so helpful" 😉
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Prof Jenny Rohn @jennyrohn.bsky.social · 21/04/2026
OMG - STAMP, what a technique! Would love to try this. Bacteria with 200 different barcodes so you can track infection dynamics through a tissue. Here, Kieran Toms using it to track intracerebral Listeria clonality and spread 👏 #ESCMIDGlobal2026
A slide showing a brain, a mouse and some bacteria explaining the STAMP technique
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Gabriele Pollara @gpollara.bsky.social · 19/04/2026
Normal urine is not sterile! Urine microbiome being introduced by @nicoledenisco.bsky.social #ESCMIDGlobal2026 #UTISky
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Dr Neil Stone @drneilstone.bsky.social · 21/04/2026
It's not only Cefiderocol Increasing observation of Aztreonam-Avibactam resistance, especially in China We are losing these drugs before most people even have access to them...😩 #EscmidGlobal2026
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Dr Neil Stone @drneilstone.bsky.social · 21/04/2026
Sobering talk from Timothy Walsh from Oxford, UK on the rising antibacterial resistance even to the NOVEL agents For example we are already seeing growing reports of Cefiderocol resistance - and we have barely started using it. As usual we are being outrun by the bacteria #EscmidGlobal2026
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Dr Neil Stone @drneilstone.bsky.social · 20/04/2026
URINE IS NOT A STERILE SITE BACTERIA DOES NOT EQUAL INFECTION
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Dr Neil Stone @drneilstone.bsky.social · 20/04/2026
The old chestnut of Tazocin or Meropenem for ESBL bacteraemia The PeterPen study interim results have thrown the cat amongst the pigeons @angelahuttner.bsky.social did a great job analysing it and comparing to MERINO Bottom line -this debate ain't going away any time soon #escmidglobal2026
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Bug Pharmacist // Tim Gauthier @idstewardship.bsky.social · 20/04/2026
📊 Looking at Bluesky and X, the science community is still stronger on X from what I’m seeing with #ESCMIDglobal2026 content cc: @absteward.bsky.social @krutikamh.bsky.social @drneilstone.bsky.social
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Dr Neil Stone @drneilstone.bsky.social · 20/04/2026
Tremendous day at #escmidglobal2026 Interim results of the PeterPen trial by Mical Paul Year in ID - A superb overview from Dafna Yahav Not to be missed if you can catch them online
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Krutika Kuppalli, MD FIDSA @krutikakuppalli.bsky.social · 20/04/2026
Key take-home at #ESCMIDGlobal2026: 🧬 Partial cross-reactive immunity to H5 exists 💉 Likely from prior seasonal influenza exposure ⚠️ May not prevent infection—but could blunt severity 👉 Population not fully naïve to H5N1 👀
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Krutika Kuppalli, MD FIDSA @krutikakuppalli.bsky.social · 20/04/2026
Next up at #ESCMIDGlobal2026 🧬 Whole genome sequencing–guided precision medicine for rifampicin-resistant TB (SMARTT trial) 🎯 Goal: tailor therapy → shorten treatment A major step toward individualized TB care 👀
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Krutika Kuppalli, MD FIDSA @krutikakuppalli.bsky.social · 20/04/2026
SMARTT trial design at #ESCMIDGlobal2026: 🧬 WGS-guided therapy → individualized regimens ⏱️ Goal: shorten RR-TB treatment (~6 months vs standard longer courses) 🌍 Pragmatic, real-world setting in South Africa Precision medicine moving TB care from standardized → tailored 👀
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Krutika Kuppalli, MD FIDSA @krutikakuppalli.bsky.social · 20/04/2026
The last paper in this session at #ESCMIDGlobal2026 💊 Adjunctive steroids in Mycoplasma pneumoniae CAP 🫁 Target: hypoxemic hospitalized adults 📊 RCT evidence now emerging ❓ Key question: do steroids improve outcomes—or risk harm?
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Josh Davis @gurujosh.bsky.social · 20/04/2026
David Paterson at #ESCMIDGlobal2026 Highlights important issue of generic versus brand name meropenem – previous work has suggested chemical differences, harder to dissolve and even higher mortality with generic preparations
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Krutika Kuppalli, MD FIDSA @krutikakuppalli.bsky.social · 20/04/2026
Highlights from late-breaking @TheLancet at #ESCMIDGlobal2026 📊 🔹 WGS + AI for RR-TB → better outcomes 🔹 UTI → nitrofurantoin best; fosfomycin worst 🔹 H5 immunity → partial cross-protection 🔹 M. pneumoniae CAP → steroids speed recovery 🚀 Precision + smarter antimicrobial use are shaping ID
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Antibiotic Steward 🅱️C🆔🅿️🌟 @absteward.bsky.social · 20/04/2026
🔥Late Breakers PeterPen RCT prelim results challenges carbapenem default in ESBL BSI Pip/tazo vs MER (EI) ✅Non-inferior 7d failure(29.4% vs 33.5%) ❌No early mortality signal 30d mortality 14.4%(interim) 👉Will mortality follow?MERINO taught us the hard way! #ESCMIDGlobal2026 #IDsky
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Antibiotic Steward 🅱️C🆔🅿️🌟 @absteward.bsky.social · 20/04/2026
▶️💥When the fairy dust settles: critical appraisal of presented trials Excellent talk by Prof.HUTTNER @angelahuttner.bsky.social How did PeterPen replicate the MERINO trial? Co-intervention bias? Are you going forward to 1000 patients for 30d mortality? Did you get FUBC? 🌟7d? #ESCMIDGlobal2026
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Dr Neil Stone @drneilstone.bsky.social · 20/04/2026
Back on home territory for me..fungal disease Then future of biomarkers for invasive fungal infection...we've been focusing on the pathogen..time to focus on host biomarkers Beautifully presented by Laura Alcazar Fuol 🇪🇸 #escmidglobal2026
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Angela Huttner @angelahuttner.bsky.social · 19/04/2026
Listening to @drneilstone.bsky.social talk about Twitter vs Bluesky in Arena 3: Says don’t concede space in Twitter to anti-science influencers #ESCMIDGlobal2026 #IDSky #clinmicro
Dr Neil Stone talking at a podium showing slides
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Prof Jenny Rohn @jennyrohn.bsky.social · 19/04/2026
Despite its worldwide prevalence, research about #UTI is sparse here at #ESCMIDGlobal2026. But managed to find a concentrated mini-population of researchers at the poster session niche—enriched for the London strain, but quite a small sample size, p values not reaching significance! #UTISky #IDSky
Smiling selfie 1Smiling selfie 2
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Angela Huttner @angelahuttner.bsky.social · 19/04/2026
From Carl Sagan via @neilstone.bsky.social “When we are unable to distinguish between what feels good and what's true, we will side, almost without noticing, back into superstition and darkness.” #ESCMIDGlobal2026 #IDSky #clinmicro
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ESCMID @escmid.bsky.social · 19/04/2026
ESCMID is shaping the future of #infectiousdiseases care through evidence-based guidelines that strengthen diagnosis and treatment. The open call for guideline projects is now live! Join the open meeting at #ESCMIDGlobal2026 in 1 hour, and get involved in what comes next.
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Dr Neil Stone @drneilstone.bsky.social · 19/04/2026
Phase II trial of giving probiotics in allogeneic stem cell transplants to reduce infectious complications Well tolerated but unfortunately didn't show any benefit #escmidglobal2026
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Dr Neil Stone @drneilstone.bsky.social · 19/04/2026
Screening patients for colonisation of drug resistant organisms can help reduce carbapenem use and duration of antibiotics in febrile neutropenia #escmidglobal2026
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Dr Neil Stone @drneilstone.bsky.social · 19/04/2026
Day 3 of #escmidglobal2026 here in Munich 🇩🇪 Bugs on the menu..food borne pathogen Dr Megan Carey on XDR typhoid which continues to spread
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Oliver Cornely @olivercornely.bsky.social · 18/04/2026
Day 2 at #ESCMID - great to see first contributions from Cologne! 🙌 Starting with an oral session on viral infections in immunocompromised hosts, chaired by @salmantongarcia.bsky.social from our team. Amazing Bavarian-style atmosphere, sunshine & beer garden vibes ☀️🍻 #InfectiousDiseases #Science
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Krutika Kuppalli, MD FIDSA @krutikakuppalli.bsky.social · 18/04/2026
Key IPC takeaways from #ESCMIDGlobal2026 👀 🔹 Quality > compliance (hand hygiene) 🔹 Gel Nail polish may not ↑ risk 🔹 PICCs: “antimicrobial” ≠ better 🔹 Gowns: limited added value 🔹 PPE ↓ possible without ↑ infections 🔹 Microplastics → emerging AMR risk Data should drive practice.
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Krutika Kuppalli, MD FIDSA @krutikakuppalli.bsky.social · 18/04/2026
Microplastics & AMR—an emerging concern 👀 🔹 Enhance E. coli biofilms & select for more resistant cells 🔹 Effects persist even after removal 🔹 May act as a catalyst—implications for biofilm infections & hospital sinks/drains Environmental exposure may be driving AMR #ESCMIDGlobal2026
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Dr Neil Stone @drneilstone.bsky.social · 18/04/2026
Interesting phase II trial of adding Daptomycin to Ceftriaxone for pneumococcal meningitis in France 🇫🇷 Needs more study but encouraging signal for a reduction in disability #escmidglobal2026
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Eli Perencevich @eliowa.bsky.social · 18/04/2026
“Year in Infection Control” papers #ESCMIDGlobal2026 talk by Nico Mutters Papers highlighted included @jamanetworkopen.com study jamanetwork.com/journals/jam...
jamanetwork.com
Plastic Waste and COVID-19 Among Hospital Staff After Deescalation in PPE Use
This quality improvement study evaluates whether personal protective equipment (PPE) deescalation guidelines in Singapore was associated with staff COVID-19 incidence as well as the environmental sust...
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David van Duin @davidvanduin.bsky.social · 18/04/2026
Now up: a change of pace looking at how new antibacterials should be evaluated. Conducting stand-alone two-arm trials very time and money consuming. Dr. Melissa Hardy proposes GNR research should take a page out of SNAP playbook and conduct platform trials instead. #ESCMIDGlobal2026
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Gabriele Pollara @gpollara.bsky.social · 18/04/2026
For those that don't know (included me!), Gremubamab binds specifically to the Pseudomonas aeruginosa PcrV protein and the Psl exopolysaccharide. Both are virulence factors used for adhesion and biofilm stability. Thanks @microsoft-copilot.bsky.social ! #ESCMIDGlobal2026 #IDSky #ClinMicro
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Dr Neil Stone @drneilstone.bsky.social · 18/04/2026
The ALLIUM trial Novel antibiotic cefepime -enmetazobactam is non inferior vs piperacillin-tazobactam for pyelonephritis #escmidglobal2026
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Dr Neil Stone @drneilstone.bsky.social · 18/04/2026
Fascinating new approach to pseudomonas in bronchiectasis...the novel bispecific antibody Gremubamab #escmidglobal2026
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Dr Neil Stone @drneilstone.bsky.social · 18/04/2026
Oral carbapenem Great new tool? Or the gateway to resistance hell? #escmidglobal2026
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Dr Neil Stone @drneilstone.bsky.social · 18/04/2026
Nacubactam - a novel antibiotic which in combination with aztreonam looks a promising new therapy for difficult to treat carbapenem resistant organisms #escmidglobal2026
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Krutika Kuppalli, MD FIDSA @krutikakuppalli.bsky.social · 17/04/2026
🧫 136 million hospital-associated #AMR infections occur globally every year. Not a projection. The current reality. At #ESCMIDGlobal2026, the message is clear: antimicrobial resistance doesn’t pause for austerity. Smarter policy isn’t optional — it’s survival. #AntimicrobialResistance
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Krutika Kuppalli, MD FIDSA @krutikakuppalli.bsky.social · 17/04/2026
The economic case for IPC. Per @who.int: every $1 invested in hand hygiene yields $24.60 in economic gain. Global IPC implementation could generate $112B in healthcare savings + $124B in economic gains. IPC is one of the smartest investments health systems can make. #ESCMIDGlobal2026
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Bug Pharmacist // Tim Gauthier @idstewardship.bsky.social · 17/04/2026
🪦Mortality outcomes can require huge participant numbers, other things matter. #ESCMIDglobal2026 …I will be posting more videos like this as 1 of 4 official social media ambassadors for the congress 🙏 so please share, follow, like and use the official hashtag when posting!! 2/n @escmid.bsky.social
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ESCMID @escmid.bsky.social · 17/04/2026
Trainee Association of ESCMID (TAE) Day lands at #ESCMIDGlobal2026 this Saturday with a revised and exciting programme for #clinicalmicrobiology and #infectiousdiseases trainees! Connect directly with leading experts for honest conversations about careers and what comes next.
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Cristina Loader (she/her) @crisloader.bsky.social · 17/04/2026
At #ESCMID this afternoon and looking for something genuinely worthwhile? Join our two-hour educational session: Clinical Challenges in Tropical Medicine, lessons for global health. 🕐 13:30–15:30📍 Session Hall ICM 5 We have an outstanding group of speakers from across the globe #ESCMIDGlobal2026
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Onisillos @onisillos.bsky.social · 17/04/2026
If papers in @lancetmicrobe.bsky.social get mentioned at #ESCMIDGlobal2026 I’d love to hear about it
media.tenor.com
a black cat is peeking out from behind a cabinet
ALT: a black cat is peeking out from behind a cabinet
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ESCMID @escmid.bsky.social · 17/04/2026
Get ready for #ESCMIDGlobal2026 on the move 📱 Download the official mobile app to explore the programme, view session replays, network and stay up to date, all while keeping your personalised agenda in sync throughout the congress!
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ESCMID @escmid.bsky.social · 17/04/2026
Join the conversation by using #ESCMIDGlobal2026 and stay connected to live discussions, key insights and updates from across the programme in real time.
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rbentvelsen.bsky.social @rbentvelsen.bsky.social · 17/04/2026
Good start of my #ESCMIDGlobal2026 with best practices on stewardship, interpretation, detection limitations and clinical management through the #antibiogram from Norway by dr Lindemann, dr Jeannot, dr Stefani and dr Howe. #CPE #MRSA
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