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Jenn Kim

@drjennkim.bsky.social
153 followers 256 following 23 posts

🧠 postdoc @lieberinstitute.bsky.social studying reward circuits in addiction and development • previously @ubc @sfstatebio.bsky.social @ucsantabarbara.bsky.social • proud dog mom 🐾

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Reposted by Jenn Kim
Jay Gallagher @jay-gallagher.bsky.social · 15/09/2026
🐟🚨 New paper! 🚨🐟 Where do behavioral differences come from? Early life environment clearly matters... ...or not? Early environment affected behavior, but NOT how different individuals became from each other. Those differences were seeded before birth through factors OTHER than genetic variation 🤯
onlinelibrary.wiley.com
Born This Way: Individuality Is Seeded Before Birth and Robust to Ecological Stress
We reared and recorded behaviours of clonal Amazon mollies in standardized environments, with and without predation stress, from birth through week four of life, to understand how the developmental e...
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Reposted by Jenn Kim
Liisa Galea @liisagalea.bsky.social · 09/09/2026
Our new preprint with @ciernialab.bsky.social we investigated transcriptional profiles of microglia (❤️the name) from hAPOEe4/3 female/male mice in HPC &CTX. We saw loads of sex x genotype interactions in both regions Cell cycling, ER stress, lipid metabolism ++ www.biorxiv.org/content/10.6...
biorxiv.org
Sex and APOE Genotype Differentially Shape Microglial Transcriptomic Profiles Across the Hippocampus and Cortex
Female sex and the APOEε4 allele are top risk factors for Alzheimer’s disease (AD). Microglia play a role in the pathogenesis of AD, yet how sex and APOE genotype affect microglia remain poorly unders...
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Bernie Mulvey @berniejmulvey.bsky.social · 11/09/2026
Excited to share work with cryostat wizard @heenadivecha.bsky.social looking at gene expression in my favorite brain region (LC) in adult postmortem brain! (Long URL to spare the trouble of identifying cars, buses, beds in 5x5 pixel imgs). (1/x) link.springer.com/epdf/10.1007...
link.springer.com
Molecular programs in human locus coeruleus link APOE and neuromelanin to Alzheimer’s vulnerability
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Michael Totty @mictott.bsky.social · 27/08/2026
Incredibly proud to share our newest work where we developed a multiscale spatial transcriptomic atlas of the human amygdala using three complementary technologies! 1/12 🧵 www.biorxiv.org/content/10.6...
biorxiv.org
Multiscale spatial transcriptomics resolves the cellular and molecular architecture of the human amygdala
The amygdala is a central hub for emotional learning that is dysregulated across numerous psychiatric disorders, yet its molecular architecture in humans remains poorly defined. We here present a spat...
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Jenn Kim @drjennkim.bsky.social · 21/08/2026
me too, it’s the perfect friday ☺️ huge thanks to @jorge-miranda.bsky.social for being the best teacher!
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Jenn Kim @drjennkim.bsky.social · 21/08/2026
definitely one of my core postdoc memories ✨ happy to join the #patchcult
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Robin Magnard @robinmagnard.bsky.social · 30/07/2026
🧠🧬 What are the effects of intravenous fentanyl self-administration on the habenula and amygdala transcriptomes? In our new Addiction Biology paper, we addressed this question using a chronic long-access model in rats! Here are some highlights 🧵👇 Paper 👉 dx.doi.org/10.1111/adb....
dx.doi.org
Transcriptional Response to Chronic Long‐Access Fentanyl Self‐Administration in Rat Habenula and Amygdala
Chronic intravenous long-access fentanyl self-administration in rats produced transcriptional remodeling in the habenula and amygdala. Bulk RNA-sequencing identified 453 habenula and 3,041 amygdala d...
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Reposted by Jenn Kim
Soyon Hong @soyonhonglab.bsky.social · 10/07/2026
Thrilled to share: we show that neuronal hyperactivity drives C1q-mediated synapse loss via brain-recruited B cell/IgM, revealing unexpected neuroimmune crosstalk in the adult brain. Congrats to Gerard Crowley who led this w/ resilience & creativity & our whole team! www.science.org/doi/10.1126/...
science.org
C1q and immunoglobulins mediate activity-dependent synapse loss in the adult brain
Complement component 1q (C1q), the initiator of the classical complement cascade, mediates synaptic elimination in development and disease, yet the triggers for its deposition on synapses remain uncle...
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Reposted by Jenn Kim
Ed Banigan @irate-physicist.bsky.social · 12/07/2026
waited until nearly the last minute, but I joined 250k+ others and submitted a comment on the disastrous OMB proposal for rule changes to federal funding of science. used the great thread/articles quoted below. comment here: www.federalregister.gov/documents/20...
federalregister.gov
Regulation for Federal Financial Assistance
The Office of Management and Budget (OMB) proposes to revise the Guidance for Federal Financial Assistance to improve government- wide policies and requirements related to the management of grants, co...
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Reposted by Jenn Kim
Jorge Miranda Barrientos @jorge-miranda.bsky.social · 26/06/2026
Thrilled to share that our latest paper investigating how mPFC-LC projectors contribute to sustained #attention is now out in @npp-journal.bsky.social This is so meaningful to me and the team, Its @rehg-j.bsky.social first first-author paper and my first corresponding one. rdcu.be/fqBJp
rdcu.be
Top-down control of sustained attention by medial prefrontal cortex—locus coeruleus (mPFC-LC) projection neurons during the rodent continuous performance test (rCPT)
Neuropsychopharmacology - Top-down control of sustained attention by medial prefrontal cortex—locus coeruleus (mPFC-LC) projection neurons during the rodent continuous performance test (rCPT)
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Keri Martinowich @martinowk.bsky.social · 10/06/2026
Excited to see this preprint from @drjennkim.bsky.social @kr-maynard.bsky.social, Annie Ciernia and colleagues. I've highlighted this approach and toolset in several recent talks: spatial transcriptomics isn't just about the gene expression - www.biorxiv.org/content/10.6...
biorxiv.org
Spatially-resolved integration of microglia morphological diversity and gene expression using Visium with protein co-detection
Microglia exhibit a dynamic range of morphologies that actively shift in response to local environmental cues. There has been a concerted effort as a field to move away from dualistic characterization...
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Keri Martinowich @martinowk.bsky.social · 02/06/2026
Grateful for some absolutely spectacular weather ☀️ for our annual cross-research teams spring party!!
A group of people sitting on a dock
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Kenneth Harris @kenneth-harris.bsky.social · 19/05/2026
New method for identifying the fine transcriptomic types of thousands of neurons recorded in vivo!
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Justus Kebschull @justuskebschull.bsky.social · 17/05/2026
New from the lab: BARseq3! Barcodes + high efficiency spatial transcriptomics and translatomics in the same cells, or just a nice spatial transcriptomics assay. All in a modular, expandable system to enable truly multimodal measurements. Check it out: www.biorxiv.org/content/10.6...
biorxiv.org
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Dayu Lin @moccalin.bsky.social · 14/05/2026
Happy to share our new review on Neural Mechanisms of Social Hierarchy across Species. We discussed different routes to achieve high social status across species, from fish to humans, and the neural circuits that support each of those strategies. www.nature.com/articles/s41...
nature.com
Neural basis of social hierarchy across species
Nature Reviews Neuroscience - Structured social hierarchies, in which individuals differ in their access to resources and influence over other group members, are a characteristic of many social...
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Jenn Kim @drjennkim.bsky.social · 26/03/2026
@libdrstats.bsky.social videos and blog posts continue to be a great resource for me as I delve into snRNAseq analyses, and for lots of other bioinformatics-related topics! Learn more here: research.libd.org/rstatsclub/
research.libd.org
LIBD rstats club
Continuous rstats learning
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Jenn Kim @drjennkim.bsky.social · 26/03/2026
Check out my first @libdrstats.bsky.social presentation on one strategy our team @lcolladotor.bsky.social at @lieberinstitute.bsky.social is taking to deal with doublets during quality control for single nucleus RNA-sequencing data: www.youtube.com/watch?v=SMA-...
youtube.com
[2026-02-27] Strategy to drop doublets during snRNAseq QC steps
YouTube video by Leonardo Collado Torres
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Mariko Bennett @nachoriko.bsky.social · 24/03/2026
I defended my PhD 10 years ago today. That was the least remarkable thing that happened that day. Sharing something I wrote about it last year. Since then "the horrors persist but so do we." And with dignity.
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Karl Deisseroth @deisseroth.bsky.social · 15/03/2026
Great work from Claire, Ravi, and the whole team– the initial lifelong continuous screen of behaving vertebrates provided a wealth of ideas on progression/staging of brain function across lifespan. Behavior is unmatched as a noninvasive quantitative readout of brain function (and, one that matters).
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Reza Shadmehr @rezashadmehr.bsky.social · 15/03/2026
Today I received a note from a grad student who lives in Tehran. Her note gives you firsthand experience of what it’s like to live in a city that is being bombed, and what it’s like to be young and feel despair about your future. rezashadmehr.blogspot.com/2026/03/hope...
rezashadmehr.blogspot.com
Hopeless in Tehran
Essays on neuroscience
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Jenn Kim @drjennkim.bsky.social · 15/03/2026
😍 looks like a lovely time!
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Reposted by Jenn Kim
Keri Martinowich @martinowk.bsky.social · 09/03/2026
Super excited about these #FluorescentFriday images 🔬🧪 as part of project led by @drjennkim.bsky.social in @kr-maynard.bsky.social lab to understand the molecular anatomy of VTA-NAc circuitry in the developing human 🧠
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Joshua Weitz @joshuasweitz.bsky.social · 07/03/2026
The data is in: the NIH goalposts have shifted. What were once almost certain fundable scores have become coin flips and what used to be likely grants have become aspirational, leading to fewer awards. Another manifestation of how HHS policies have led to fewer awards and less science.
Graph of award probability of R35 and R01 from NIH factbook as a function of review rank percentile. As is apparent, 2025 is a significant departure, with lower award probabilities at all scores <40 and significant departures from norm, where even being in the top 10% is no longer a nearly certain indicator of success.

Data source: https://report.nih.gov/nihdatabook/report/302
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Jenn Kim @drjennkim.bsky.social · 07/03/2026
#FluorescenceFriday to mark my first foray into human neuroanatomy @lieberinstitute.bsky.social 🧠 RNAscope of marker genes for the ventral tegmental area (VTA) and nucleus accumbens (Ac) in the developing human brain
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Reposted by Jenn Kim
Sang Ho (Sangho) Kwon @shkwon-bcmbneuro.bsky.social · 18/02/2026
FIRST post here on Bluesky - we’re excited to share that our large spatial transcriptomics study of the human dlPFC in schizophrenia is now available on bioRxiv📄: www.biorxiv.org/content/10.6... (1/9)
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Jenn Kim @drjennkim.bsky.social · 14/02/2026
#patchcult 😎
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Headquarters @headquartersnews.bsky.social · 09/02/2026
Bad Bunny sends a message at the Super Bowl: "God Bless America" "The only thing more powerful than hate is love"
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Keri Martinowich @martinowk.bsky.social · 09/01/2026
Honored to be appointed Chief Scientific Officer @lieberinstitute.bsky.social. LIBD is a uniquely collaborative place with extraordinary biological resources and a commitment to translation 🧠🔬🧪. Grateful to my colleagues and excited to help guide our next chapter! www.libd.org/keri-martino...
libd.org
Keri Martinowich, Ph.D., Chief Scientific Officer | The Lieber Institute for Brain Development | Research & Discovery
Lieber Institute for Brain Development Appoints Keri Martinowich, Ph.D., as Chief Scientific Officer Baltimore, MD (January 6, 2025) — The Lieber Institute for Brain Development (LIBD) announced the a...
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Jenn Kim @drjennkim.bsky.social · 01/01/2026
Happy new year from Ollie & Bella 🐾 May your 2026 be as cozy and warm as these two ❤️
Ollie (left, black and white dog) and Bella (right, brown and white dog) cuddling nose to nose
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Alex Kwan @alexkwan.bsky.social · 15/12/2025
“Basic neuroscience hasn’t produced new drugs.” 💊 Not true - zuranolone (PPD), suzetrigine (pain), gepants (migraine), and more... were born out of a long arc of studies in the lab. I wrote a Perspective on why this matters. @thetransmitter.bsky.social www.thetransmitter.org/drug-develop...
thetransmitter.org
How basic neuroscience has paved the path to new drugs
A growing list of medications—such as zuranolone for postpartum depression, suzetrigine for pain, and the gepants class of migraine medicines—exist because of insights from basic research.
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Jason Rehg @rehg-j.bsky.social · 15/12/2025
Finally on Bluesky and I’m really excited to share this latest preprint with @jorge-miranda.bsky.social in which we functionally examined the role of a medial prefrontal cortex (mPFC)- Locus Coeruleus (LC) circuit in regulating sustained attention. 1/7 www.biorxiv.org/content/10.6...
biorxiv.org
Top-down control of sustained attention by the medial prefrontal cortex (mPFC)- locus coeruleus (LC) circuit during the rodent continuous performance task (rCPT)
The medial prefrontal cortex (mPFC) plays a pivotal role in attention by exerting top-down control to allocate cognitive resources toward behaviorally relevant stimuli based on learned context and exp...
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Reposted by Jenn Kim
Louise Huuki-Myers @lahuuki.bsky.social · 11/12/2025
Excited to share our latest preprint from @lieberinstitute.bsky.social spatial + single-cell RNA-seq map the ERC & explore how AD risk shapes gene expression doi.org/10.1101/2025... Our major finding: “APOE E4 Alzheimer’s Risk Converges on an Oligodendrocyte Subtype in the Human Entorhinal Cortex”
Experimental design for LIBD LFF Spatial ERC project
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Fabian Theis @fabiantheis.bsky.social · 10/12/2025
Excited to share new preprint led by Sergio Salas on “unassigned RNAs” in imaging-based spatial transcriptomics. Across technologies, 30-40% of transcripts fall outside segmentation, & many show structured, biologically meaningful extrasomatic patterns. 📄 www.biorxiv.org/content/10.6...
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Keri Martinowich @martinowk.bsky.social · 07/11/2025
Our paper using endoscopic in vivo calcium imaging to uncover how neuronal population dynamics in the prelimbic cortex track attention and task engagement during the rodent continuous performance test (rCPT) is now online www.nature.com/articles/s41...
nature.com
Patterns of neural activity in prelimbic cortex neurons correlate with attentional behavior in the rodent continuous performance test - Translational Psychiatry
Translational Psychiatry - Patterns of neural activity in prelimbic cortex neurons correlate with attentional behavior in the rodent continuous performance test
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Nature Portfolio @natureportfolio.nature.com · 07/11/2025
Scientists point to a long list of findings that emerged out of fundamental research, the type of studies the US government is cutting, and went on to change the world. Nature lists a few of their examples. 🧪
go.nature.com
7 basic science discoveries that changed the world
Ozempic, MRI machines and flat screen televisions all emerged out of fundamental research decades earlier — the very types of study being slashed by the US government.
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Jenn Kim @drjennkim.bsky.social · 06/11/2025
And ofc, an unforgettable time with the best class 😎 huge thank you to all the course leaders and lecturers for the fun and incredible learning experience! 3/
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Jenn Kim @drjennkim.bsky.social · 06/11/2025
Also had the opportunity to generate/analyze our own data, which was really useful to solidify all the new concepts we learned about. Some fun lab pics fr/ preparing virus, dissecting brain regions for MAPseq, brain tissue clearing, and in situ sequencing our BARseq-prepped tissue on the scope 🤩 2/
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Jenn Kim @drjennkim.bsky.social · 06/11/2025
Had the most rewarding time at the HTNA #cshlcourses It was fun science-ing all day/night for 2wks to learn modern viral, whole 🧠 imaging & barcode-based seq approaches to understand neuroanatomy/function. Inspired & energized as I think of all the ways these tools can be applied in my own work!🧪 1/
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bioRxiv Neuroscience @biorxiv-neursci.bsky.social · 04/11/2025
Circuit-specific gene editing for precision modulation of neuronal activity with CRISPR-rabies virus www.biorxiv.org/content/10.1101/202…
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Louise Huuki-Myers @lahuuki.bsky.social · 04/11/2025
Proud to announce our paper ‘Transcriptomic Analysis of the Human Habenula in Schizophrenia’ from @lieberinstitute.bsky.social is the cover article for the November issue of the American Journal of Psychiatry! 🧠 #HabenulaLIBD #snRNAseq #Habenula doi.org/10.1176/appi...
doi.org
Transcriptomic Analysis of the Human Habenula in Schizophrenia | American Journal of Psychiatry
Objective: The objective of this study was to define the molecular neuroanatomy of the human habenula (Hb) and identify transcriptomic differences between brains of individuals with schizophrenia and ...
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Kevin Terretaz @kwolbachia.bsky.social · 04/11/2025
My new ImageJ / Fiji toolkit is out 🔥! The goal is to make image handling & visualization easy, with an intuitive interface! Install it on Fiji with the "Image Viewer" update site #microscopy #ImageJ #FluorescenceFriday #microscopyMonday imagej.net/plugins/imag...
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🇲🇽 Leonardo Collado-Torres @lcolladotor.bsky.social · 24/10/2025
"What Makes a Good Data Visualization?" 🤔 Check @christinezhang.bsky.social's 🤩 excellent 💯 guest lecture for 140.776 Statistical Computing at @johnshopkinssph.bsky.social 📽️: youtu.be/SeLucCb05Dk Slides: speakerdeck.com/lcolladotor/... #RStats @jhubiostat.bsky.social @lieberinstitute.bsky.social
youtu.be
[2025-10-16] What Makes a Good Data Visualization?
YouTube video by Leonardo Collado Torres
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Amy Gleichman @amygleichman.bsky.social · 11/10/2025
Thrilled to share this work from my postdoc with Tom Carmichael, available online @ Neuron! Long story short: we find even more evidence that all reactive astrocytes are not equal, and we can take advantage of those differences to improve repair after stroke. www.sciencedirect.com/science/arti...
sciencedirect.com
Regionally mapped astrocytic responses to cortical and white matter stroke show differential roles in astrocyte-induced vascular remodeling
Stroke is a major cause of disability. Astrocytes respond to stroke in a gradated manner, but details of that response and its consequences for tissue…
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Crystal Rogers, PhD @rogerslabucd.bsky.social · 30/09/2025
Effective and empathetic scientific communication is so critical right now. We had an interactive workshop at the #2025ICDB led by @rebeccacalisi.bsky.social and Dr. Kevin Alicea-Torres and facilitated by @spiraldoc.bsky.social and myself- and we practiced this. Please check out our perspective!
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Katie Wilkinson @drkwilkinson.bsky.social · 27/09/2025
All scientists can easily respond to this and you can choose to stay anonymous. I modified my comment from the FASEB response. We all know that international scientists are essential to US science and that these proposed rules are cruel to our colleagues. www.regulations.gov/comment/ICEB...
regulations.gov
Regulations.gov
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Keri Martinowich @martinowk.bsky.social · 25/09/2025
We have several positions open at various levels (Research Assistant, Research Associate, Postdoctoral Fellow) across our highly interactive teams in the Division of Translational Neuroscience 🧠🔬🧪 @lieberinstitute.bsky.social www.libd.org/careers/ Links to individual positions in the thread below.
libd.org
Careers at LIBD | Medical Research Jobs | Lieber Institute
View our career opportunities with Lieber Institute for Brain Development including investigators, medical research jobs, scientists, & lab techs
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Jimmy Kimmel @jimmykimmel.com · 24/09/2025
As I was saying…
youtu.be
Jimmy Kimmel is Back!
YouTube video by Jimmy Kimmel Live
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John Ngo @johntngo.bsky.social · 22/09/2025
🚀 Our new paper is out @natmethods.nature.com! Kuffer & Marzilli engineered conditionally stable MS2 & PP7 coat proteins (dMCP & dPCP) that degrade unless bound to RNA, enabling ultra–low-background, single-mRNA imaging in live cells. 🔗 www.nature.com/articles/s41... 🧬 www.addgene.org/John_Ngo/
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Dominique Baker @bakerdphd.bsky.social · 20/09/2025
Look at academia giving me a little hope
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Allen Orr @allenorr.bsky.social · 20/09/2025
The Trump Administration has announced measures to gut longstanding pathways based on exceptional ability, national interest, & merit in favor of pay-to-play immigration. @urbanviewradio.bsky.social This sends a signal to the world’s top talent that the U.S. is closing its doors. bit.ly/4nz1XBE
bit.ly
AILA: Trump Administration H-1B Crackdown and “Gold Card” Visa Imperil Jobs, Innovation, and Rural Healthcare
AILA President Jeff Joseph and ED Ben Johnson responded to the Trump Administration attempting to apply a new $100,000 fee to H-1Bs and supplant existing visa programs with a “Gold Card” visa, noting ...
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