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Dr. CSP

@drcsp.bsky.social
459 followers 1.1K following 245 posts

Retired scientist. Clinician. Artist. Mom. I hope something good happens to you today.

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Reposted by Dr. CSP
PessoaBrain @pessoabrain.bsky.social · 27/05/2026
What is the minimal machinery needed for complex, cognition-like behavior? Very cool.
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Dominique Baker @bakerdphd.bsky.social · 22/05/2026
Well that's a thorough summary. One of the best articulations of university governance for a public audience that I've seen in a while.
Screenshot of article which reads: This  is how you end up with an elite university where the president can drive his car into a group of students and be lauded by the board. The president and the trustees are on the same team. The students are on the other team. The trustees know Kotlikoff will reliably enforce their agenda, including cracking down on protests that might be bad for cashflow. It almost doesn’t matter what he does; if there’s any conceivable defense, they’ll keep him in place. (If not, they’ll replace him with someone else who can talk about loving free speech while moving to crush it in practice.) Kotlikoff, after all, has already proved his worth: It was on his watch that Cornell agreed to pay $60 million to the U.S. government to get Trump to unfreeze its research grants.
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Carl T. Bergstrom @carlbergstrom.com · 22/05/2026
"An email from NIH’s National Institute of General Medical Sciences (NIGMS) to research-center grantees, seen by Science, requires their institutions to promise that U.S. authors of papers NIH has flagged because of foreign co-authors will not collaborate with them in the future."
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Alejandra Caraballo @esqueer.net · 20/05/2026
Breaking: the 1st circuit denied the emergency injunction request by the Rhode Island child advocate. As a result, Rhode Island children's will have to turn over medical records of trans youth to judge Reed O' Connor in Texas within the next 45 minutes. storage.courtlistener.com/recap/gov.us...
storage.courtlistener.com
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Tony Beales @tonybeales.bsky.social · 20/05/2026
Here's a Scottish badger for a change. I think this is the matriarch of the sett having a look around. From other shots it is obvious she is feeding young cubs at the moment. #UKwildlife #mammals
A daylight shit of a badger emerging from the sett, raised up high on her front legs and looking half right (to left of photo).
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Elizabeth Wrigley-Field @wrigleyfield.bsky.social · 20/05/2026
I bought this cookbook, despite its distinctly unpromising title, because a cookbook roundup by Dan Kois said that it had increased his family’s vegetable consumption by 200-300%, & I‘ve become a huge fan Not always the best for quick weeknight dinners, but extremely delicious dinners even 4yo eats
hettymckinnon.com
Tenderheart — Hetty McKinnon
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Tina Smith @smith.senate.gov · 20/05/2026
Nothing makes someone look guiltier than forcing the Justice Department to promise never to investigate your taxes or prosecute you for anything they might find
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neocolonial malcontent chic @azadirachta-indica.bsky.social · 18/05/2026
"The point is to wander through physics. Even if math terrifies you, you are entitled to spend some time with it." BOOM. @chanda.blacksky.app probably just took a booster dose to my years of accumulated educational hurt (signified crucially by, but not limited to, maths)
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Aaron Sojourner @aaronsojourner.org · 18/05/2026
We did things that disemployed almost 6 million US manufacturing workers. It's not job destruction that blocks policy. It's profit destruction.
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Laurel @laurelfynes.bsky.social · 17/05/2026
Blossoms I have smelled this morning. Well, the plum and lilacs had a fragrance, not so much the redbud and apple. It’s spectacular out here this morning.
A red-leaved plum tree covered in little, round-petalled pink flowers with dark pink centres.Redbud tree, bright pink flowers opening along all the branches, bright blue sky behind it.Closeup on apple blossoms, pink buds with pale pink flowers on branches with bright green leaves. Classic mauve lilac flowers opening on green branches.
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Holly @hollyrandersen.bsky.social · 18/05/2026
We can end gun violence. We don’t have to live like this. To the land of the free: this is not what freedom looks like.
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Spook-ass, Christ oh boo! boo! @loukas.bsky.social · 18/05/2026
Now would be a great time for a social-economic historian of WW1 and/or WW2 to drop a thread about how wartime production of food and logistics shaped what we nowadays think of as 'British' or 'American' food. This is BlueSky. I know you must be out there.
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TDr. Linda Maepa (born at 325ppm) @lmaepa.blacksky.app · 18/05/2026
After turning off predictive text on my keyboard, the typos were wayyyyy up and the typing speed in the gutter. I was committed to my path. 3/4 days, turns out it was mostly bad habits reinforced by predictive text. Everything's good now 💅🏾 What other "habits" has tech formed in me? In others?
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Dr. Holly Walters @manigarm.bsky.social · 17/05/2026
I just can't get past "What do you mean I have to check AAALLLLLLLL my citations?" Like, dude, what? My PhD advisor would have hung me by my toenails on the quad if I didn't know what one of my citations was for.
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Mark @njdoc.bsky.social · 17/05/2026
www.medscape.com/viewarticle/...
medscape.com
First Lyme Vaccine in Decades Nears Approval
Positive phase 3 findings may reshape Lyme disease prevention among people with frequent tick exposure across endemic regions.
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z. @zanadu.bsky.social · 17/05/2026
A thing! I hear it! #CatsOfBluesky
A brownish and black tabby cat, Obi-Wan Katnobi, with a white chin and very prominent ears. She is alert. She is standing with her front paws on the bottom of her kitty condo.
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Daniel Summers @danielrsummers.bsky.social · 16/05/2026
Highly encourage folks to listen to Dr. Topol's conversation with @donmilton.bsky.social and read that NYT piece. Spillover events will continue happening with increasing frequency, public health must adapt and adopt maximally cautious approaches to transmission to contain future outbreaks.
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Brant Reeves @bireeves95.bsky.social · 17/05/2026
This Needs to Happen…. Idea: a law that says if you’re going to build a data center, you have to also build enough solar panels to power it. We can call it the Bring Your Own Damn Grid Act.
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Emma Mitchell @silverpebble2.bsky.social · 16/05/2026
Younger daughter & I found these fossilised crinoid rock stars (segments of the ‘stem’ of Jurassic feather stars/sea lilies, related to starfish & sea urchins) in the gravel on the edge of a lake nr Peterborough UK. She used them to make an ammonite:
A spiral of crinoid ossicles from the Jurassic arranged in a spiral according to size on a white glazed plate
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FrontRangeWildflowers @frwildflowers.bsky.social · 16/05/2026
Ponderosa bark puzzle 🌿 Sisters Trail today
Reddish brown bark looking like a jigsaw puzzle
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Lupita Nihongo @otsumamiboy.blacksky.app · 17/05/2026
The Onion should do a satire with a good outcome just to see if they can manifest it.
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Tina Hoggatt @thoggatt.bsky.social · 17/05/2026
Janet always brings the bird joy.
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Miiriya @miiriya.com · 16/05/2026
Really wish I could go viral on BlueSky. I created an app that merges Mutual Aid with Black Businesses: on the app, you can shop Black Businesses on 1 app, all Black Owned conveniently under 1 roof. On the same app you can see people struggling with overdue bills/rent/evictions etc & give them aid.
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David M. Perry @lollardfish.bsky.social · 17/05/2026
… we have lost much of the civil rights act, most of roe v wade, most of the EPA, any remnants of a progressive tax code, the voting rights act. I’ll be shocked if the ADA makes it through the next two years. I want to vote for candidates who recognize the scope and are ready to try new things.
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Raysident Evil @sireviscerate.myatproto.social · 07/02/2024
Under 'medical history', we were hoping for something more specific to you personally. You wrote "Fleming discovered penicillin in 1928".
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Brian Phillips @brianphillips.lol · 15/05/2026
The president of Cornell hit some students with his car, lied about what happened, and cast himself as the victim. Cornell's trustees, palpably aghast at the idea that a powerful man could be held accountable for his actions, have issued an official statement saying fuck the students
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Mara 👻 aBOOlish I.C.E. @mauratwit.bsky.social · 15/05/2026
Use alt text so everyone can enjoy your photos and graphics!
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Nature @nature.com · 15/05/2026
The personalized treatment encourages the immune system to attack glioblastomas go.nature.com/4uliVYg
go.nature.com
Bespoke DNA vaccine offers hope for treatment of notorious brain cancer
The personalized treatment encourages the immune system to attack the tumours called glioblastomas.
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Mike Hutchinson @hutchymon.bsky.social · 15/05/2026
Dog and cottonwood fluff
A golden retriever on a path lined by drifted cottonwood fluff
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I Scare You Like Sound Dog @chadstanton.blacksky.app · 15/05/2026
“The result: more than 4 million people — a cohort the size of Los Angeles’ population — have already lost SNAP since the law took effect. Hunger prevention advocates say Black Americans have been disproportionately affected, and that the worst is still ahead.” wordinblack.com/2026/05/hung...
wordinblack.com
Hunger By Policy: SNAP Cuts Hit Hardest in Black America
Supplemental Nutrition Assistance Program recipients in several states now have work requirements and other restrictions.
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UAINE @mahtowin1.bsky.social · 15/05/2026
Without tribal consultation, US Bureau of Land Management cancelled the “Public Land Rule" that required BLM to consider conservation & development equally in land-use decisions. This leaves millions of acres across the West vulnerable to oil/gas extraction & mining. www.kotatv.com/2026/05/14/f...
kotatv.com
Feds officially cancel conservation rule for public lands
The Bureau of Land Management has officially rescinded the 2024 Public Land Rule, removing guidance that required conservation to be weighed equally with development on public lands.
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The Contrarian @contrariannews.org · 15/05/2026
"True democracy was ushered in and kicked out in my mother’s lifetime. When she was 15, Black people like her finally were granted the right to vote and now at 76 saw 6 members of SCOTUS declare that, for all intents and purposes, especially now as a FL resident, she no longer has those rights."
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Ethan Siegel @startswithabang.bsky.social · 14/05/2026
Do we even promote science at the NSF anymore? Or is this just a way to divert the already starved funds away from physics, astronomy, biology, chemistry, and geosciences towards AI, computation, and any grifter who uses the word "quantum" slyly enough? Asking for a concerned planet.
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Martin Rücker @martinruecker.bsky.social · 14/05/2026
"Breaking the vicious cycle: How two German scientists seek to solve #ME" #MECFS - my latest article has just been published by @thesicktimes.org thesicktimes.org/2026/05/14/b...
thesicktimes.org
Breaking the vicious cycle: How two German scientists seek to solve ME - The Sick Times
A “unifying” hypothesis of the mechanisms, triggers, and risk factors for myalgic encephalomyelitis (ME), is gaining support. Further evaluation and development of a potential drug depend on funding.
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Christopher Mims @mims.bsky.social · 14/05/2026
I have nearly unlimited (and often early) access to all the AI, and my #1 productivity unlock of the past year has been to revert to taking handwritten notes. I even re-learned cursive to make it faster.
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Corey Rayburn Yung @coreyryung.bsky.social · 14/05/2026
The Trump administration is not anti-fraud. It's anti-government-assistance to the poor and minorities. "Anti-fraud" is just the newest eupheminism for it. The administration is decidely pro-fraud. The media needs to be explicit about this and not just uncritically convey Trumpist talking points.
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April Glick Pulito @aprilglick.bsky.social · 14/05/2026
I feel I should alert Bluesky to the baby foxes in our yard
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Sarah Rose @thesarahrose.bsky.social · 13/05/2026
The good taxpayers of New York have given me a pair of Meta glasses because I am low vision disabled, and I seem to have used them more than a lot of people on here, so let me say a little about my experiences:
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emily blight 🐦‍⬛ @threnody.northsky.social · 14/05/2026
gwen does fantastic work as usual on some of the 401,000 trans people who’ve had to flee hostile territory in their own country in the past 18 months.
Poster which shows color photo scene of moving, a room with boxes and clothes sitting on the floor, a chair, and the end of a bed (white rails forming a headrest and a mattress with a red cover). The text of the poster is: "Impact (small logo top left)," "According to a new survey by the Movement Advancement Project, approximately 401,000 transgender people have relocated from one U.S. state to another since the 2024 presidential election." "The mass relocations in 2025 due to safety concerns, political conditions, and anti-trans laws nd policies have largely impacted conservative states across the country."
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Timothy McBride @mcbridetd.bsky.social · 14/05/2026
STAT+: MIT says research has fallen 10%, and grad student enrollment is down www.bostonglobe.com/2026/05/14/b...
bostonglobe.com
‘A loss for the nation.’ MIT president says research has fallen 10 percent, and grad student enrollment is down - The Boston Globe
Total research funding has dropped 10 percent from a year ago while the school expects to enroll 500 fewer graduate students in the next academic year.
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Dr. CSP @drcsp.bsky.social · 13/05/2026
Best article I have read this week- it’s always fun to read about brilliant scientists and their brilliant ideas but I love love love it when people lead with their full humanity. Really looking forward to reading her book
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Dr Surekha Davies, Historical Monster Consultant (she/her) @drsurekhadavies.bsky.social · 13/05/2026
"A piece of this book is me saying there is value in banding with the poets, and fighting for the value of being curious and trying to articulate the world with whatever tools are available to us. Not for the purposes of selling something, but for the purpose of fulfilling our humanity.” 1/ 💙📚 🧪
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Dr. Damien P. Williams, dread portent down from a mountain cave @wolven.blacksky.app · 05/09/2024
Every good thing this society half-assedly started due to COVID should've been not just continued but constantly improved upon; but too many of y'all have The Fear, & those programs remind you of the thing that scared you. So instead you burn down your house 'cause your basement made spooky shadows
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Dr. CSP @drcsp.bsky.social · 13/05/2026
Every time I read about this it blows me away. So cool.
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John Greally @greally.bsky.social · 13/05/2026
1/ There is a bill going through the New York State legislature that would transform our ability to provide medical genetics care: www.nysenate.gov/legislation/...
nysenate.gov
NY State Assembly Bill 2025-A3229A
Prohibits insurance companies from discriminating based on genetic predisposition including refusing to issue or renew, charging any increased rate, or restricting any length of coverage; prohibits insurers from requiring genetic testing.
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Mark Peifer (He, him) @peiferlabunc.bsky.social · 13/05/2026
While BioNtech & Moderna become household names because of their Covid vaccines, those emerged from different projects: finding ways to treat the most challenging cancers. They hypothesized that we could vaccinate patients against their own tumors, & evidence is mounting that they were right! 1/n 🧪
https://www.nature.com/articles/s41586-025-10004-2
Individualized mRNA vaccines evoke durable T cell immunity in adjuvant TNBC

    U. Sahin, M. Schmidt, E. Derhovanessian, A. Cortini, I. Vogler, T. Omokoko, E. Godehardt, S. Attig, S. Newrzela, J. Grützner, N. Bidmon, S. Bolte, S. Brachtendorf, T. Stuhlmann, D. Langer, D. Brüne, J. Blake, A. Feldner, H. Lindman, A. Schneeweiss, M. Eichbaum & Ö. Türeci 
Triple-negative breast cancer (TNBC) is frequently associated with metastatic relapse, even at an early stage1. Here we assessed an individualized neoantigen mRNA vaccine in 14 patients with TNBC following surgery and after neoadjuvant or adjuvant therapy. In peripheral blood of nearly all patients, high-magnitude, vaccine-induced, mostly de novo T cell responses to multiple neoantigens were detected that remained functional for several years. Characterization of individual patients revealed that a large proportion of these T cells developed into two subsets: a late-differentiated phenotype with markers indicative of ‘ready-to-act’ cytotoxic effector T cells, and T cells with a stem cell-like memory phenotype. Eleven patients remained relapse-free for up to six years post-vaccination. Recurrence occurred in three patients: the individual with the weakest vaccine-induced T cell response relapsed, but achieved complete remission on subsequent anti-PD-1 therapy; another patient had a tumour with low major histocompatibility complex (MHC) class I expression with MHC class I-deficient cells growing out under vaccination; and the third patient was BRCA-positive and had a recurrence from a genetically distinct primary tumour. These findings demonstrate the feasibility of individualized RNA vaccines in TNBC, document persistence of vaccine-induced, functional neoantigen-specific T cells and provide insights into possible immune escape mechanisms that will guide future approaches.
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