Efficient coupling of cellular energy status to ribosome regulation is fundamental for cellular survival. Here, we identify the Archaeal Ribosome regulatory Complex (ARC)—a previously uncharacterized ...

Ribosome hibernation preserves translation machinery during stress. Here, the authors identify a ribosome hibernation factor that is widespread in archaea and combines bacterial HPF/RaiA-like and cyst...

Hibernation factors preserve ribosomes during cellular dormancy. Here, the authors identify a family of archaeal hibernation factors and use genetic, biochemical, and structural studies to show how th...

Ribosome hibernation helps cells survive stress by reversibly silencing translation and preserving ribosomal complexes. Although well characterized in bacteria and eukaryotes, archaeal hibernation rem...

Ribosome hibernation helps cells survive stress by reversibly silencing translation and preserving ribosomal complexes. Although well characterized in bacteria and eukaryotes, archaeal hibernation rem...

Contribute to leepusp/ppigfinder development by creating an account on GitHub.

Sequence and structural analyses reveal a divergent peptidyl transferase centre and a hibernation factor in archaea.

The emergence of cell compartmentalization depends on membrane fission to create the endomembrane compartments. In eukaryotes, membrane fission is commonly executed by ESCRT-III, a protein complex con...

Asgard archaea have two ESCRT-III subunits with the conserved traits that drive stepwise membrane remodeling in eukaryotes.