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ERR_Moody

@emoody.bsky.social
623 followers 356 following 39 posts

Computational Evolutionary Biologist. Focusing on deep nodes in the tree of life. University of Barcelona linktr.ee/err_moody

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Systematics Association @systassn.bsky.social · 23/09/2026
We are delighted to announce the speaker for this year's Founders' Lecture: Dr. Mark Wilkinson, @nhm-london.bsky.social and former SystAssn president! TITLE: Caecilians and the growth of knowledge WHEN: Thursday, October 8th at 6PM WHERE: Burlington House, London JOIN US: tinyurl.com/ndx5az2a
Poster with details and QR code to register for the SystAssn Founders' Lecture
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Hady George @houdzgeorge.bsky.social · 16/09/2026
Welcome Dinodontosaurus isiyavamanda! I'm delighted to introduce you to a new species of protomammal. Hailing from the Triassic of Tanzania, this is the first record of Dinodontosaurus outside of South America, and it informs on the origin of dinosaurs. Here's a thread summarising our findings 🧵
Life reconstruction of two Dinodontosaurus isiyavamanda individuals by Gabriel UguetoSkull and jaw of the holotype of Dinodontosaurus isiyavamanda. Original photos by Jonathan Jackson
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Hady George @houdzgeorge.bsky.social · 16/09/2026
Finally, huge thanks to my coauthors, I couldn't have done it without them, only the phylogenetics wizard @emoody.bsky.social is on this platform. Also, thanks goes to @serpenillus.bsky.social for the stunning artwork. You can read the full research article here: tandfonline.com/doi/full/10....
tandfonline.com
Craniomandibular osteology of Dinodontosaurus isiyavamanda sp. nov. (Therapsida: Anomodontia) from the Manda Beds of Tanzania and new support for a younger age for the alleged oldest dinosaurs
Fossils from the Manda Beds of Tanzania have greatly informed on the diversity and evolution of Triassic tetrapods, including on what might be the oldest dinosaurs. Here, a new dicynodont taxon fro...
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ERR_Moody @emoody.bsky.social · 12/08/2026
Managed to snap some photos of the eclipse as seen from my parents'garden in the UK, telescope set-up courtesy of @petermoody.bsky.social
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DaganLab @daganlab.bsky.social · 09/08/2026
📢 We have an open PhD position to study the evolution of antibiotic resistance plasmids! Ad and Application (English below): jobs.uni-kiel.de/jobposting/8... Candidates who read the recommended papers (see ad) will be well positioned to prepare a strong application. Deadline: 6. Septermber 2026.
jobs.uni-kiel.de
wissenschaftliche*r Mitarbeiter*in Zielrichtung Promotion
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Sandra Álvarez @sabifo4.bsky.social · 03/08/2026
Registrations are open to attend the Computational Molecular Evolution course next year (May 9th - 20th) in wonderful Crete! ☀️ Do not miss the deadline, follow the link below for more info and registration details! 🔽 meetings.embo.org/event/27-com...
meetings.embo.org
Computational molecular evolution
The need for effective and informed analysis of biological data is increasing with the explosive growth of genomic data. A phylogenetic framework is central to many molecular evolutionary approaches …
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Alexis Stamatakis @stamatak.bsky.social · 17/07/2026
Applications for the 2027 summer school on Computational Molecular Evolution on Crete are now open at: meetings.embo.org/event/27-com...
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Francesco Cicconardi @fcicconardi.bsky.social · 12/07/2026
1/4 I met Claudio (Cucini) at the @sibe-iseb.bsky.social meeting in 2022 and asked if he’d like to collaborate on springtails. A few years and many discussions later, our first preprint is finally out! Here are some highlights… #Phylogenomics #Evolution #Collembola #Systematics
biorxiv.org
Ancient Rapid Radiation Underlies Persistent Phylogenomic Conflict in Early Collembola Diversification
Collembola (springtails) are among the most abundant and ecologically important soil arthropods, representing one of the oldest extant terrestrial hexapod lineages, with a fossil record extending to t...
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ssolo.bsky.social @ssolo.bsky.social · 04/07/2026
Ancestral genome reconstructions get noisier the deeper in time you go. The usual response: distrust them and joke about reading entrails. Ours is to train on the noise! The result is calibrated phenotype prediction back to the LBCA deep in the Archaean. New preprint www.biorxiv.org/content/10.6...
biorxiv.org
Models trained with noisy genomes extend bacterial phenotype prediction into deep time
Predicting phenotype from genotype in extant organisms is increasingly tractable through the accumulation of genome sequences and the development of machine-learning algorithms. Here we show that mach...
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ERR_Moody @emoody.bsky.social · 30/05/2026
Very exciting to see this out at last, we use both sequence-based and structural phylogenetics to try and understand the pre-eukaryotic origins of the commander complex! Also some serious protein crystallography and cryo-EM, (five new pdb entries!) www.nature.com/articles/s41...
nature.com
The prokaryotic origins of the COMMD protein family involved in eukaryotic membrane trafficking - Nature Communications
COMMD proteins assemble into a heterodecameric ring in the Commander complex, which plays a role in endosomal membrane trafficking and signalling in eukaryotes. Here, Liu et al. identify COMMD-like pr...
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Daniel Tamarit @danieltamarit.bsky.social · 22/05/2026
I'm looking for an enthusiastic student to join my team as a PhD candidate on archaeal genome evolution 🦠💻 Work in beautiful Utrecht, at @binfutrecht.bsky.social, an international group full of caring, amazing scientists, and with frequent cake breaks! www.uu.nl/en/organisat... Please share! 🙏
uu.nl
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ERR_Moody @emoody.bsky.social · 10/04/2026
Excited to announce a speedy new multiple-sequence alignment trimming software, led by Giorgio Bianchini: academic.oup.com/mbe/advance-... AliFilter aims to replicate manual trimming through learnt features, make your own model! Tutorial and docs here: github.com/arklumpus/Al... #phylogenetics
academic.oup.com
AliFilter: a Machine Learning Approach to Alignment Filtering
AbstractIntroduction. Multiple sequence alignments are a crucial step in many bioinformatic and computational biology analyses, from protein structure and
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Fiona J Whelan @whelanfj.bsky.social · 13/03/2026
📣 The Whelan lab is hiring a bioinformatics postdoc 📣 Together with @fabricejpierre.bsky.social, we are offering a 1-year bioinformatic PDRA position in comparative genomics of Pseudomonas aeruginosa. To find out more please visit whelanlab.co.uk/contact/. Applications close 3 April 2026!
jobs.manchester.ac.uk
Research Associate in Microbial Genomics:Manchester
This postdoctoral research position is part of a Cystic Fibrosis Canada Early Career Investigator Award funded for 3-years led by Dr. Fabrice Jean-Pierre and Dr. Fiona Whelan. The aim of this project is to identify the genetic changes that arise in the Pseudomonas aeruginosa genome following perturbations – such as antibiotic treatment – in an in vitro system. The PDRA will use a large dataset of P. aeruginosa genomes and experimental metadata to predict key mutationsto the organism.
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The Palaeontological Association @thepalass.bsky.social · 26/02/2026
The Palaeontological Association has written to the President of the University of Leicester, requesting that the concerns of the PhD community over the planned redundancy of their supervisors are addressed. [1/3]
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Carl T. Bergstrom @carlbergstrom.com · 24/02/2026
1. Kevin Gross and I have a new paper out today PLOS Biology. We used economic models based around screening games and the market for unpaid labor to highlight a meltdown cycle threatening peer review.
journals.plos.org
Screening, sorting, and the feedback cycles that imperil peer review
The process of peer review is vital to contemporary science, but is also under enormous strain. This study uses mathematical models to dissect the threats to the long-term viability of peer review, su...
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James McInerney @jomcinerney.bsky.social · 14/10/2025
Last day to apply to come work with me on developing AI approaches to understanding pangenome evolution www.jobs.ac.uk/job/DOU184/p...
jobs.ac.uk
Postdoctoral Research Associate - Grade 7 at University of Liverpool
An opportunity for an academic position as a Postdoctoral Research Associate - Grade 7 is available, as advertised on jobs.ac.uk. Apply now and explore other academic job openings.
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ERR_Moody @emoody.bsky.social · 02/10/2025
Excited to announce I have officially joined the University of Barcelona for my Marie Skłodowska-Curie Actions fellowship! I'll be working with Jesus Lozano Fernandez in the DeepEvo lab at the @geneticsub.bsky.social, on various deep nodes in the tree of life!
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Brett Collins @brettcollins.bsky.social · 03/09/2025
🧵In collaboration with Caroline Puente-Lelievre, Ed Moody, Rosie Cater, and Tom Williams we just submitted a new paper describing the prokaryotic origins of the COMMD protein family. @cpuentelelievre.bsky.social‬, ‪@rosemaryjcater.bsky.social‬. @kmichie.bsky.social‬. 1/n
biorxiv.org
The prokaryotic origins of the COMMD protein family involved in eukaryotic membrane trafficking
The ten eukaryotic COMMD proteins are core components of the Commander complex, with central roles in endosomal membrane trafficking and signalling. Each protein has an α-helical N-terminal (HN) domai...
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Romain Strock @romainstrock.bsky.social · 15/08/2025
This first-author publication is my… first! Archaea kill bacteria by targeting their Achilles’ heel: peptidoglycan. Big shoutout to @ahocher.bsky.social‬, @valeriesoo.bsky.social‬, Pauline Misson, @tobiaswarnecke.bsky.social‬ and MRC LMS Proteomics. A thread 🔽 journals.plos.org/plosbiology/...
journals.plos.org
Archaea produce peptidoglycan hydrolases that kill bacteria
Archaea regularly interact with bacteria but reports of archaea killing bacteria are very rare. This study shows that many archaea encode peptidoglycan hydrolases, which specifically target bacterial ...
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Philip Donoghue @phil-donoghue.bsky.social · 11/08/2025
The proceedings volume from our Nov24 meeting on the evolution of biospheres is just in PhilTransB @royalsocietypublishing.org delivering insights into how our biosphere evolved - and how other biospheres may evolve
royalsocietypublishing.org
Philosophical Transactions of the Royal Society B: Biological Sciences: Vol 380, No 1931
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ERR_Moody @emoody.bsky.social · 12/08/2025
Very happy to announce our new paper on the evolution of metabolism is out now! royalsocietypublishing.org/doi/10.1098/... With @tweethinking.bsky.social @sabifo4.bsky.social @ssolo.bsky.social Davide Pisani, Tim Lenton and @phil-donoghue.bsky.social (1/2)
royalsocietypublishing.org
The emergence of metabolisms through Earth history and implications for biospheric evolution | Philosophical Transactions of the Royal Society B: Biological Sciences
We investigate the evolution of microbial metabolisms from the last universal common ancestor to the extant biota through comparative phylogenomics, reconciling the evolution of the genes that underpi...
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Kim Chandler @kimchandler.bsky.social · 06/08/2025
Great to see some nice news articles out about the new display we've been working on @dublindeadzoo.bsky.social ! 🦓🐢🐇🦥🦇 www.irishtimes.com/ireland/dubl...
irishtimes.com
New lease of life: Dead Zoo Lab brings back beloved Natural History Museum collection
Collins Barracks is displaying about 1,300 objects while original Merrion Street location undergoes refurbishment
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ERR_Moody @emoody.bsky.social · 01/07/2025
Our paper on VPS29 is out now! Pleased to have been part of the team: www.pnas.org/doi/10.1073/...
pnas.org
Identification of a VPS29 isoform with restricted association to Retriever and Retromer accessory proteins through autoinhibition | PNAS
The endosomal–lysosomal network is a hub of organelles that orchestrate the dynamic sorting of hundreds of integral membrane proteins to maintain c...
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Saioa Manzano-Morales @microbiobits.bsky.social · 16/06/2025
(1/14) ¿Has probado alguna vez a trazar tu árbol genealógico? Es un ejercicio interesante para entender tus raíces, a pesar de que se complica cuantas más generaciones atrás intentas llegar… Imagínate un árbol así, pero a escala de toda la vida en la Tierra. #HiloDivulgación
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Max Farnworth @maxfarnworth.bsky.social · 07/05/2025
Really happy to share our new preprint on the central complex of Heliconiini butterflies www.biorxiv.org/content/10.1.... Check it out! @neuroethology.org @brainevolutionnews.bsky.social @prelights.bsky.social @tibbe-evolneuro.bsky.social #brainevolution #heliconius #centralcomplex
biorxiv.org
Distinct evolutionary trajectories of two integration centres, the central complex and mushroom bodies, across Heliconiini butterflies
Neural circuits have evolved to produce cognitive processes that facilitate a species variable behavioural repertoire. Underlying this variation are evolutionary forces, such as selection, that operat...
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Prof Sam Illingworth @samillingworth.com · 10/04/2025
☕🌊 Coffee too weak? Pour more slowly A new study found that even a gentle water jet creates avalanches in coffee grounds, boosting mixing and extraction. Slower pours = stronger brews with less coffee. 🔗 doi.org/10.1063/5.02... #Coffee #SciComm 🧪
doi.org
Pour-over coffee: Mixing by a water jet impinging on a granular bed with avalanche dynamics
Coffee is one of the most consumed beverages in the world. However, issues such as climate change threaten the growth of the temperature-sensitive Coffea arabic
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Matthew Hahn @3rdreviewer.bsky.social · 10/04/2025
Not really my announcement to make--I am but a lesser co-author--but IQ-TREE 3 has just been released! (Most credit to Minh Bui and @roblanfear.bsky.social and their labs) ecoevorxiv.org/repository/v...
ecoevorxiv.org
IQ-TREE 3: Phylogenomic Inference Software using Complex Evolutionary Models
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the Node @the-node.bsky.social · 10/04/2025
Featured image with Allan Carrillo-Baltodano This is an image of a larva of a phoronid worm. To swim, the larva propels itself using cilia 💃 Find out about @allancarbal.bsky.social and his #EvoDevo research on marine annelids: thenode.biologists.com/featured-ima...
Actinotroch larva of a phoronid worm with phalloidin shown in yellow and acetylated tubulin in magenta. Imaged with a Zeiss LSM 800 at 10 x magnification
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Margot Finn @eicathomefinn.bsky.social · 09/04/2025
'Bluesky has overtaken its flailing rival X in hosting posts related to new academic research, indicating the platform is fast becoming the go-to place for scholars to share their work.'
timeshighereducation.com
X’s dominance ‘over’ as Bluesky becomes new hub for research
Data indicates more scholars turning to alternative social media site to post about their work after Elon Musk’s Twitter takeover
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ERR_Moody @emoody.bsky.social · 04/04/2025
Ecstatic to have played a small part in this, we find that the first aerobes predate the GOE by almost a billion years! Photosynthesis implications Lead by Adrián Davín, @benjwoodcroft.bsky.social @xrefugee13.bsky.social @tweethinking.bsky.social @ssolo.bsky.social www.science.org/doi/10.1126/...
science.org
A geological timescale for bacterial evolution and oxygen adaptation
Microbial life has dominated Earth’s history but left a sparse fossil record, greatly hindering our understanding of evolution in deep time. However, bacterial metabolism has left signatures in the ge...
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Masaru Nobu @masarunobu.bsky.social · 27/02/2025
New isolates from eukaryote's closest archaeal relative: ‘Hodarchaeales’!! Syntrophic microaerotolerant peptide-degrading anaerobic archaea w/ simple cell structure & protrusions. Features conserved across the phylum provide new insight into our ancestor’s biology! www.biorxiv.org/content/10.1...
biorxiv.org
Eukaryotes' closest relatives are internally simple syntrophic archaea
Eukaryotes are theorized to have originated from an archaeal phylum Promethearchaeota (formerly 'Asgard' archaea)1,2. The first cultured representatives revealed valuable insight3,4 but are distantly ...
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EvolDir @evoldir.bsky.social · 20/02/2025
Three-year postdoc in computational evolutionary biology at the University of Glasgow. Ideal for PhD holders in bioinformatics. Applications close on March 18, 2025. More info: vibelab.co.uk #postdoc
vibelab.co.uk
VIBE Research Lab
Viral Informatics, Biostatistics, and Evolution Research Lab at the CVR, University of Glasgow
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Philip Donoghue @phil-donoghue.bsky.social · 18/02/2025
Job Alert: Senior Research Associate in Phylogenomics @bristolpalaeo.bsky.social researching timing, sequence and phenotypic consequences of rediploidisation following whole genome duplication - comparative genomics, molecular clock and phenotypic disparity methods, with @jameswclark.bsky.social
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Tom Williams @tweethinking.bsky.social · 18/02/2025
Job announcement: a four-year postdoc position in phylogenomics at the Milner Centre for Evolution, Bath, with James Clark and me (I'm moving to Bath later in the year...). www.bath.ac.uk/jobs/Vacancy...
bath.ac.uk
ED12442 Research Associate in Phylogenomics (fixed-term) - Jobs at Bath
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Laura Kelly @laura-j-kelly.bsky.social · 17/02/2025
PDRA opportunity at Kew - chance to work on an exciting new project with a wonderful boss! (speaking from first hand experience ☺️)
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Emily Mitchell @egmitchell.bsky.social · 13/02/2025
How may evolutionary rates vary on different planets? See our preprint where we think how temperature impacts the timings of the origins of major groups
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Dr. Becca @docbecca.bsky.social · 12/02/2025
Now hanging prominently in lab so we always remember why we’re here and that what we do matters
A print out of the letter in the previous post’s link
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Anja (she/her) @anja1.bsky.social · 12/02/2025
Are you interested in studying archaea with their diverse symbionts? We look forward hearing from you: workingat.nioz.nl/o/postdoc-po...
workingat.nioz.nl
NIOZ - Postdoc position: “to elucidate the role of archaeal symbionts in cellular evolution and ecology”
The EvoSym Team within the Department of Marine Microbiology and Biogeochemistry (MMB) located at the Netherlands Institute for Sea Research (NIOZ), is looking for a postdoctoral researcher with a bac
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Arthur Charles-Orszag @acharlesorszag.bsky.social · 05/02/2025
Mark your calendars! Archaea power hour is back!
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MRC Laboratory of Molecular Biology @mrclmb.ac.uk · 11/02/2025
New research on ancient Asgard archaeal ESCRT-III proteins reveals evolutionary secrets of membrane remodelling. Diorge Souza, Javier Espadas and Sami Chaaban, investigated the ESCRT-III proteins with Buzz Baum and Aurelien Roux. Read more: www2.mrc-lmb.cam.ac.uk/asgard-archa... #LMBResearch (1/2)
Evolution, structure and membrane remodelling function of the ESCRT-III superfamily in eukaryotes and their closest relatives Asgard archaea. The two subfamilies, B-type and A-type, have distinct structural properties to perform sequential steps of the membrane remodelling pathway.
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ERR_Moody @emoody.bsky.social · 08/02/2025
Really cool project to work on, happy to see it out!
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Diorge Souza @diorgeps.bsky.social · 08/02/2025
Happy to share our paper’s final version on the evolution, structure, and membrane binding / remodeling of Asgard ESCRT-III proteins! And my first 🦋 post! www.science.org/doi/10.1126/...
science.org
Asgard archaea reveal the conserved principles of ESCRT-III membrane remodeling
Asgard archaea have two ESCRT-III subunits with the conserved traits that drive stepwise membrane remodeling in eukaryotes.
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Nature Ecology & Evolution @natecoevo.nature.com · 14/01/2025
January Editorial: We look back at papers published in NEE in 2024 www.nature.com/articles/s41... #1 Cited: 🔥 Extreme wildfires www.nature.com/articles/s41... #1 Accessed: 🦠 The nature of LUCA www.nature.com/articles/s41... #1 Altmetric: 🐘 Name-calling elephants www.nature.com/articles/s41...
All 12 cover images from Nature Ecology & Evolution during 2024
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Kim Chandler @kimchandler.bsky.social · 15/01/2025
Delighted to have the first paper of my PhD out in Royal Society Open Science royalsocietypublishing.org/doi/10.1098/...
royalsocietypublishing.org
Morphological change in an isolated population of red squirrels (Sciurus vulgaris) in Britain | Royal Society Open Science
The mechanical properties of dietary items are known to influence skull morphology, either through evolution or by phenotypic plasticity. Here, we investigated the impact of supplementary feeding of p...
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Robert Sansom @fossilrob.bsky.social · 13/01/2025
PhD project opportunity here in Manchester to do some cool inter-disciplinary stuff on the taphonomy and fossil record of collagen. Ancient, recent, modern, lab-work, theoretical, data, imaging, its all there! Deadline Jan 31st www.findaphd.com/phds/project...
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ERR_Moody @emoody.bsky.social · 09/01/2025
These predatory journal email addresses are slowly getting scarier.
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Falk Hildebrand @bioinf.bsky.social · 07/01/2025
New vacancy in my lab: explore microbial evolution in metagenomes in a 2 year post @TheQuadram @EarlhamInst , UK: quadram.ac.uk/vacancies/re... (closes 27th Jan) You will have access to unique software, 3rd gen deeply sequenced unique human cohorts.
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ERR_Moody @emoody.bsky.social · 19/12/2024
Wow! A real honour to be included on this year's list, thanks @quantamagazine.bsky.social and of course all the vital collaborators involved in the work youtu.be/p9XHI_26cPE?...
youtu.be
2024's Biggest Breakthroughs in Biology and Neuroscience
YouTube video by Quanta Magazine
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Vaughn Cooper @vscooper.micropopbio.org · 12/12/2024
I’m proud to join more than 30 colleagues today in sharing our analysis of potential risks from “mirror life”. We summarize our findings in a @science.org article, and in greater detail in a 300pg technical report: Article: www.science.org/doi/10.1126/... Report: purl.stanford.edu/cv716pj4036
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Joanna Masel @joannamasel.bsky.social · 12/12/2024
Our annotations of LUCA’s domains agree well with recent annotation of LUCA’s full-length genes by @emoody.bsky.social @phil-donoghue.bsky.social. doi.org/10.1038/s415... Recent gene-tree species-tree reconciliation methods are what made inferring LUCA possible for both groups. 13/15
Table showing that 95 of our pre-LUCA Pfams where deemed by Moody et al. to be >75% likely to be in LUCA proteins, 3 were 50-75% likely, 2 were <50% likely, and 1 was not in their dataset. For our single-copy LUCA Pfams, 672 were confirmed at the >75% level, 75 at the 50-75% level, 106 were <50%, and 15 were not in their dataset.
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