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Deepa Agashe

@deepaagashe.bsky.social
938 followers 265 following 40 posts

Curious biologist

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Sara Mitri @saramitri.bsky.social · 22/09/2026
Check out @sulheim.bsky.social's paper! The latest from our lab showing that some species do actually coexist robustly, no matter what or how much you feed them, whether the environment around them is constant, and whether or not they depend on each other metabolically for amino acids and vitamins.
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Chris Gug @gugunderwater.bsky.social · 18/09/2026
I’ve seen it >100 times, but I’ve never been about to capture it until now. Presumably, it is spawning (but I can’t be positive). But what is the green cloud, and what is the smaller blue squiggly??? #blackwater, #blackwaterdiving #polychaete
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Tobias Warnecke @tobiaswarnecke.bsky.social · 22/08/2026
Who needs chromatin anyway...? NOT THIS GUY! www.biorxiv.org/content/10.6... 1/n
biorxiv.org
Chromatin is dispensable for bacterial life
Inside cells, DNA is intimately associated with proteins, forming chromatin. The protein constituents of chromatin vary across the tree of life: histones are the principal building blocks of chromatin...
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Darrin T. Schultz @dts.bsky.social · 19/08/2026
Our new paper in Science Advances asks how animals' genomes have changed since their origin from a common ancestor over 600 million years ago, and what patterns in their DNA have arisen in the churn of speciation and extinction. www.science.org/doi/10.1126/...
Five-panel diagram explaining fusion-with-mixing in chromosome evolution. Red and blue represent two different ancestral chromosomes throughout.

A, Fusion-with-mixing: a red chromosome and a blue chromosome fuse into one half-red, half-blue bar. Down the page, successive rows show inversions, drawn as X-shaped crossings between rows, progressively interleaving the two colors until the bottom bar is finely striped. A widening gray wedge labeled Entropy runs alongside an arrow marked Time plus evolution, pointing down.

B, Independent regulation: two separate chromosomes, one red and one blue. In each, a regulatory element, drawn as an oval, acts by an arrow on a gene within its own chromosome only.

C, FWM and novel regulation: on a fused, mixed chromosome, a red gene and a blue gene now sit next to each other across an inversion breakpoint. Red and blue arrows show regulatory elements reaching across it to act on the other chromosome's gene.

D, Regulatory entanglement: an extensively mixed chromosome, finely striped. Below it, a row of alternating red and blue genes is linked by a dense web of crossing curved arrows, so many overlapping regulatory connections that unmixing the chromosome would break them.

E, Emergence of entangled loci: a five-species phylogeny. A red and a blue chromosome fuse at an ancestral node, and helical icons on later branches mark continued mixing. Colored boxes mark four new red-blue regulatory interactions arising after inversions. Species A keeps its two chromosomes separate. In species B through E, the two earliest interactions, cyan boxes 1 and 2, are present in every descendant lineage, while later ones, yellow 3 and magenta 4, appear in fewer.
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Deepa Agashe @deepaagashe.bsky.social · 02/08/2026
Thank you @dj-acid-reflux.bsky.social for Villager! Wonderfully strange to read rich stories set in the moor, while monsoon winds swoosh through big green clumps of bamboo behind me, here in India. I haven't even finished my first full read yet, and already looking forward to returning to the book.
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Vaughn Cooper @vscooper.micropopbio.org · 26/07/2026
In 2014, Jason Rosch and I met at a GRC in Tuscany and sketched an idea on a cocktail napkin: what if we evolved S.pneumo in mice, treated them with antibiotics, varied their immune systems and watched what won? 11 years and a huge team effort later, it's out in @cp-cellhostmicrobe.bsky.social 🧵
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Quentin Bacquelé @quentinbacquele.bsky.social · 23/07/2026
1/ The world's songbirds sing in just 8 basic sounds. And where a bird lives decides which ones it uses. My first PhD paper is out now in @science.org (www.science.org/doi/10.1126/science.aee6239) Here is what we found:
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Meike Wortel @meikewortel.bsky.social · 29/05/2026
Great to see this out! doi.org/10.1093/evle.... Lead by @karenbisschop.bsky.social and Thomas Blankers. It discusses: If you repeat 𝐭𝐡𝐞 𝐬𝐚𝐦𝐞 𝐞𝐯𝐨𝐥𝐮𝐭𝐢𝐨𝐧𝐚𝐫𝐲 𝐞𝐱𝐩𝐞𝐫𝐢𝐦𝐞𝐧𝐭 𝐚𝐭 𝐝𝐢𝐟𝐟𝐞𝐫𝐞𝐧𝐭 𝐢𝐧𝐬𝐭𝐢𝐭𝐮𝐭𝐞𝐬, do you get the same result in terms of fitness? The answer is… not necessarily. Glad to have played a part!
doi.org
Additive effects of environmental and demographic variation shape the repeatability of evolution across replicated experiments
Abstract. The repeatability of evolution is fundamentally important for understanding the origin and diversification of life as well as for developing evol
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European Society for Evolutionary Biology @eseb.bsky.social · 13/04/2026
📣 The ESEB Equal Opportunities Committee invites proposals for activities that increase awareness of inequalities and improve representation and equal opportunities within evolutionary biology 💰€1K grants available 👥 All ESEB members eligible to apply 🌐 Find out more: shorturl.at/7GEAo
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Alex Cope, PhD (he/him) @alexcope241.bsky.social · 13/05/2026
I'm looking for postdoc opportunities for the 2026-2027 academic year. If you're looking for a postdoc with a broad skill set spanning evolutionary genetics, bioinformatics, and various omics methods, feel free to reach out. Some recent pubs: (1) doi.org/10.1126/scie... (2) doi.org/10.1073/pnas...
doi.org
Macroevolutionary divergence of gene expression driven by selection on protein abundance
The regulation of messenger RNA (mRNA) and protein abundances is well-studied, but less is known about the evolutionary processes shaping their relationship. To address this, we derived a new phylogen...
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MichaelMcMurray lab @mcmurraylab.bsky.social · 22/04/2026
Doing the periodic cleaning of used plasmid miniprep columns and realized in honor of Earth Day it may be worth reminding you molecular biologists: Plasmid miniprep columns can be cleaned and reused essentially indefinitely! Just add 1 M HCl, soak overnight and wash 3x w/ water. Save $ and plastic
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Society for Molecular Biology and Evolution @official-smbe.bsky.social · 21/04/2026
This year's SMBE Mid-Career Excellence Award goes to Matt Pennell, professor @cornelluniversity.bsky.social Visit our website to learn more about the SMBE Faculty Awards 🔗 smbe.org/faculty-awards #society
SMBE Mid-Career Excellence Award - Matt Pennell
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European Society for Evolutionary Biology @eseb.bsky.social · 21/04/2026
Safe to say that we are very excited about this here at ESEB! Huge thanks to Brian Golding for entrusting us with the fantastic service that you have created and curated for the years! Follow @evoldir.bsky.social
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EvolDir @evoldir.bsky.social · 21/04/2026
📣 EvolDir is now managed by @eseb.bsky.social! We are delighted to be taking the reins and express our gratitude to both Brian Golding who began this service to the community in the mid-1980s and to @rdmpage.bsky.social who ran this account until now 👏 You can now find evoldir here: evoldir.net
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Eoghan Daltun 🌍 @irishrainforest.bsky.social · 06/04/2026
One of Ireland's less common butterflies, the green hairstreak, in a rewilding part of the farm yesterday. Rewilding isn't just about getting more trees and forests back, but increasing diversity and abundance of *all* our natural species and ecosystems.
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S Otto @sarperotto.bsky.social · 31/03/2026
Insightful summary of an extraordinary person being extraordinarily fired: "you don't silence a woman of color who raised concerns about racism by silencing her...The fingerprints are distributed perfectly across the system." www.linkedin.com/pulse/uclas-...
linkedin.com
UCLA's Most Decorated Ecologist Just Got Fired : Here's the sequence
In January of 2025, at the ICTP ICTS winter school at NCBS, Priyanga Amarasekare offered to take me and a few other students out for my birthday. She didn't have to do that.
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Evolutionary Applications @evolappjournal.bsky.social · 23/03/2026
Special Issue on Genetic Rescue is out 🎉🎉🎉 The 21 papers on the SI highlight how evolutionary biology can enhance resilience & long-term survival of biodiversity. Introducing genetically diverse individuals can boost fitness in small, isolated populations 🧬🌿 doi.org/10.1111/eva.70225
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Society for the Study of Evolution @sse-evolution.bsky.social · 23/03/2026
SSE offers free virtual #Evol2026 registration to all countries in our Global Membership Assistance program, including India, Brazil, Mexico, Colombia, and 152 countries and territories around the world. Request your free registration code today! www.evolutionsociety.org/index.php?mo...
Evolution 2026 meeting logo. Clilp art of a globe and laptop showing a virtual presentation. Text: Society for the Study of Evolution Global Meeting Participation.
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c0nc0rdance @c0nc0rdance.bsky.social · 26/02/2026
I can't be the only one who is made /uncomfortable/ by the way that razor clams burrow into sand, right? The final moments of this video by Kate Crump on the Oregon coastline are sort of the crowning glory of horror. 😬 But how does this even work? Let's talk about bivalve mobility (if we must).
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Deepa Agashe @deepaagashe.bsky.social · 23/02/2026
Do come listen to this public talk — open to all — by @danielbolnick.bsky.social. So happy to be hosting him in Bangalore!
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Tim Janicke @timjanicke.bsky.social · 19/02/2026
Led by my talented PhD student @justine-armg.bsky.social we’re running a #meta-analysis of #cross-sex-genetic-correlations in fitness components. If you have unpublished data or know of studies that might not appear in a systematic search, please reach out, we’d love to include them! Please share!
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Deepa Agashe @deepaagashe.bsky.social · 19/02/2026
Looking forward to this, and some fun discussion that will hopefully follow!
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Claire Willett @clairewillett.bsky.social · 07/02/2026
one of the greatest human triumphs of my lifetime is the relentless, unceasing, heroic effort by DECADES' worth of doctors and scientists to find a cure for a disease much of the world didn't take seriously for years because it predominantly affected a community they thought kinda deserved it
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Tom Cox @dj-acid-reflux.bsky.social · 05/02/2026
Solvitur ambulando is my favourite Latin phrase. It means "it is solved by walking".
A photograph I took quite early on New Year's Day, 2019, while walking on the Isle of Purbeck during the research for my book Ring The Hill, not long before I did a tweet using the photo and this same caption. I imagine it won't have as much impact here, since loads of people have since reused it, and the phrase is now more widely known. It is still very very true, though. Lots of things are solved by walking. Although not everything, obviously.
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STCmicrobeblog @stcmicrobeblog.bsky.social · 02/02/2026
#ProtistsOnSky no 'swimming' by 𝘝𝘢𝘮𝘱𝘺𝘳𝘦𝘭𝘭𝘢, definitively no 'staying still'. just a relaxed walk towards the lunch...
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Society for Molecular Biology and Evolution @official-smbe.bsky.social · 02/02/2026
SMBE is calling for nominations for Best Graduate Student Papers of 2025, recognizing outstanding papers in @molbioevol.bsky.social and @genomebiolevol.bsky.social 🗓️ Deadline Feb 27 Articles published in 2025 are eligible. The nominated student must be first author; anyone can nominate authors.
SMBE Best Graduate Student Paper
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Paula Ramiro-Martínez @paularamiro.bsky.social · 27/01/2026
New paper out in PNAS!!! 🎉 Do more plasmid copies mean faster evolution? 🧵 Dive into the story www.pnas.org/doi/10.1073/...
pnas.org
Plasmid mutation rates scale with copy number | PNAS
Plasmids are extrachromosomal DNA molecules that spread by horizontal transfer and shape bacterial evolution. Plasmids are typically present at mul...
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Isheng Jason Tsai @ishengtsai.bsky.social · 07/01/2026
Registration now open for @embo.org workshop on the evolution of biological interactions on April 24 - 27, 2026! Come join us in Taipei, Taiwan to see how interactions shaped the genomes of various organisms and meeting people from across the globe. Info: meetings.embo.org/event/26-bio...
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𝐔𝐧𝐛𝐥𝐨𝐜𝐤𝐚𝐛𝐥𝐞 𝐆𝐨𝐮𝐫𝐦𝐚𝐧𝐝 𝐂𝐫𝐚𝐛 @johnxuandou.bsky.social · 13/08/2025
This is one of the most beautiful things I have witnessed, the craft here is impeccable.
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Alex Wild @alexwild.bsky.social · 19/12/2025
A real treat to watch a male Lyrebird perform at the Healesville Sanctuary yesterday. Truly magnificent.
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Molecular Biology and Evolution @molbioevol.bsky.social · 19/12/2025
@laasya2.bsky.social @deepaagashe.bsky.social et al. quantified the growth cost of mistranslation rates and exposure to antibiotics in E. coli, finding that altered translation accuracy can shape adaptive outcomes. 🔗 doi.org/10.1093/molbev/msaf312 🖌️ Nishant Asawadekar #evobio #molbio
MBE | Cost of Altered Translation Accuracy Shapes Adaptation to Antibiotics in E. coli

Bacteria with varying levels of accuracy in protein synthesis (blue cells, using tRNAs to produce amino acid chains) face antibiotics (purple demons). Mistranslation exacts a fitness cost, and as errors increase (red amino acids), so does the cost (the red rubbish heap under each cell). Wild type, mistranslating and hyper-accurate cells also experience different ancestral fitness costs from antibiotic exposure. Strains adapt to antibiotics with varying success, using distinct mutations (represented by the nucleotide sequences).

Image credit: Nishant Asawadekar
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Deepa Agashe @deepaagashe.bsky.social · 19/12/2025
How do bacteria deal with double costs? And how costly are unusual levels of mistranslation anyway? In short - antibiotics are more of an issue than less/more mistranslation, but the latter changes how populations deal with antibiotics. For the long story, check out our new paper!
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Microbiome Virtual International Forum @microbiomevif.bsky.social · 17/12/2025
We have an early New Year present for you: 🎁The new #MVIF program is out🎁 Highlights: 🇳🇵 Bishwash Thapa 🇮🇷 Zahra Nezamivand Chegini Keynote: 🇨🇭 @saramitri.bsky.social Talks: 🇺🇸 @liliancaesar.bsky.social 🇮🇹 Haseeb Manzoor 🇦🇹 Laurenz Holcik Free registration: cassyni.com/s/mvif-45 See you in January!
MVIF 45
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European Society for Evolutionary Biology @eseb.bsky.social · 08/12/2025
The Congress Attendance Aid (CAA) Grant is offered by ESEB to promote equal participation, diversity, and accessibility @empseb31.bsky.social June 2025, Oberwiesenthal, Germany For more information and to apply click here: eseb.org/prizes-fundi...
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Jeffrey Ross-Ibarra @jrossibarra.bsky.social · 05/12/2025
A great piece below about science and art. And a great anecdote in the comments by @annfinkbeiner.bsky.social. Both ring pretty true to me.
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Sarah McAnulty, Ph.D. @sarahmackattack.bsky.social · 22/11/2025
ARTISTS! I need your help! In collab. w/the Society for Integrative & Comparative Biology, I'm organizing a group of artists to come to our Jan. meeting! We're looking for artists to create based on what they learn at the conference. $1000 stipend. Application is V short! forms.gle/ah1i8KwNJinZ...
A picture of a frog on a leaf with the SICB and Skype a Scientist logos on the bottom right with the following words on top: "Call for Artists!" Learn about the latest animal research adn create art inspired by the science at the SICB meeting in Portland, OR. Deadline to apply: dec 12, Project dates Jan 3-7, Stipend $1000"
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Society for the Study of Evolution @sse-evolution.bsky.social · 20/11/2025
Did you publish part of your PhD work in @journal-evo.bsky.social or @evolletters.bsky.social this year? Submit your paper for the SSE Presidents’ Award! Up to two recipients will each present an award talk during the virtual portion of #Evol2026 in May. Deadline: January 30. shorturl.at/CnVo6
Text: Society for the Study of Evolution SSE Presidents' Award for Outstanding Dissertation Paper, Deadline January 30. Recent covers of Evolution Letters and Evolution.
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Eduardo Valdés-Hevia 👁️ @valdevia.art · 20/11/2025
Today is my birthday! 🎂 If you like my work and want to make my day, I only ask that you share my art and stories with someone who might enjoy them :) Or trick your gullible friend for a minute. That's also a good one.
A single human skull lies on the overgrown floor. It has many faces, eyes, noses, repeating in a fractal pattern. From the cracks in the bone, a small fractal flower emerges. The water behind swirls in shimmering patterns.A picture taken from the floor of a hospital room. In the foreground, a person lies on the floor. Behind its head, their spinal cord, brain and eyes tumble outside, appearing to slither like a snake.In the far distance, way behind the mountains, a face that is too large to comprehend looks back at you, eyes wide open.A large 747 aircraft flies low close to a runway on a foggy day. The plane is completely dilapidated, with a missing cockpit area, several large holes in the fuselage and destroyed motors. It is surrounded by a coat of black smoke.
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Deepa Agashe @deepaagashe.bsky.social · 19/11/2025
Please apply for this, and/or encourage your mentees and peers to do so!
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Chris Thorogood @christhorogood.bsky.social · 19/11/2025
WE FOUND IT! We trekked day and night through tiger-patrolled Sumatran rainforests accessible only under permit for this: Rafflesia hasseltii. Few people have ever seen this flower, and we watched it open by night. Magic.
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European Society for Evolutionary Biology @eseb.bsky.social · 17/11/2025
APPLICATIONS welcomed for the ESEB #Outreach Initiative Fund for educational initiatives that promote #evolution, public outreach seminars, public exhibitions, workshops, etc. Up to €4K available per project. eseb.org/prizes-fundi...
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Hanna Kokko @kokkonut.bsky.social · 14/11/2025
For a while (many years!) back, @eseb.bsky.social gave us €€€ to form a Special Topic Network. Formally, the network no longer exists, but informally for sure AND we can now pick the fruits of our labours! Here is one and the next post shows another... Thank you ESEB! 🙏
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Chris Thorogood @christhorogood.bsky.social · 16/11/2025
Deep in the Sumatran jungle today we found the extraordinary flowers of Rhizanthes pushing their fangs through the forest floor. A sap-sucking, leafless parasite, this is one of the world's weirdest plants.
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Leonora Bittleston @leonorabit.bsky.social · 16/11/2025
I was thrilled to be interviewed by Matt Candeias for his cool podcast In Defense of Plants! Check it out if you want to hear about sagebrush, pitcher plants and leaf microbiomes! www.indefenseofplants.com/podcast/2025...
indefenseofplants.com
Ep. 551 - Sagebrush, Pitcher Plants, & Leaf Microbiomes — In Defense of Plants
In Defense of Plants' Matt Candeias talks with Microbial Ecologist Dr. Leonora Bittleston about the leaf microbiomes of sagebrush (Artemisia tridentat) and pitcher plants (Sarracenia, Nepenthes, and C...
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European Society for Evolutionary Biology @eseb.bsky.social · 13/11/2025
📣CALL FOR APPLICATIONS!! The next deadline for the #GodfreyHewitt mobility award is 31st January 2026. Open to ECRS in support of research trips or lab visits. For more information, eligibility and how to apply: eseb.org/prizes-fundi...
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Megan Behringer @megbehri.bsky.social · 13/11/2025
Excited to share our latest paper led by Ph.D. Candidate, Owen Hale, titled Elevated rates and Biased Spectra of Mutations in Anaerobically Cultured Lactic Acid Bacteria out now in mBio! journals.asm.org/doi/10.1128/...
journals.asm.org
Elevated rates and biased spectra of mutations in anaerobically cultured lactic acid bacteria | mBio
Despite Earth’s oxygen-free origins and the abundance of microorganisms that thrive without oxygen, little is known about the rates and patterns of mutations in anaerobic species. This study directly ...
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Krushnamegh Kunte @krushnamegh.bsky.social · 13/11/2025
I wrapped up field work in Siang & Dibang Valleys, Arunachal Pradesh, India, two days ago. At my last rest stop, a stunning visitor landed on the dining table, as if saying, 'don't leave!'. It was Banded Redeye (Gangara lebadea; www.ifoundbutterflies.org/gangara-leba...). I'll be back next year!
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Microbiome Virtual International Forum @microbiomevif.bsky.social · 12/11/2025
Today, join #MVIF 43! We will discuss the new bioinformatics approaches, latest findings in drug development, cancer studies and more! There's still time to register: cassyni.com/s/mvif-43
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Society for the Study of Evolution @sse-evolution.bsky.social · 30/10/2025
Now accepting nominations for the Gould Prize, which recognizes an individual who has advanced public understanding of evolutionary science and its importance. The awardee will present a public lecture at #Evol2026 in Cleveland. Nominations due January 15! shorturl.at/jornc
Text: Society for the Study of Evolution Gould Prize to recognize individuals who have increased public understanding of evolutionary biology. Nominations due January 15.
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Society for Molecular Biology and Evolution @official-smbe.bsky.social · 29/10/2025
We are excited to welcome our three new SMBE Fellows! Ioanna Kotari, Shady Kuster, and Haoran Cai will join @molbioevol.bsky.social and @genomebiolevol.bsky.social as writing fellows. Keep an eye on our next Highlight articles in MBE and GBE! #society #scicomm #evobio #molbio #genome #evolution
SMBE Fellows Program | 2025 cohort
Ioanna Kotari (University of Veterinary Medicine Vienna)
Shady A. Kuster (Colorado State University)
Haoran Cai (University of California, Los Angeles)
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