The authors use recurrent neural networks to predict how structured prior experience shapes neural dynamics as mice learn flexible timing strategies during complex context-dependent behavior.

Detecting a target odor against complex backgrounds requires separating signal from interference. McCalmon et al. show that discrimination performance depends on target odor concentration but not back...

Primary cilia are microtubule-based organelles that mediate cellular responses to environmental cues. Although cilia disassemble and reassemble upon cell cycle entry and exit, respectively, in dividin...

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Combining a computational framework and optogenetic and chemogenetic manipulations within and downstream of the cortico-basal ganglia circuit identifies the specific cortico-basal ganglia synapse...

Comprehensive atlases of olfactory sensory neuron distribution and axonal projection reveal a precise topographical organization and define spatial domains activated by social odors.

Detailed maps of smell receptors in the nose overturn textbook models of olfactory receptor organization in mice.

Dorsoventral epithelial position induces graded expression of a transcriptional program that maps each of the 1,100 olfactory sensory neuron subtypes to stereotyped spatial distributions in the epithe...

Cichy et al. show that trimethylamine (TMA), a gut microbiome-derived metabolite, activates the receptor TAAR5 in the main olfactory system to regulate aggression and social dominance in male mice. Th...

By tracking the natural actions of freely moving rats, Välikangas et al. show that prefrontal cortex encodes abstract behavioral states rather than low-level physical aspects of movement. Prefrontal a...

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Weinreb et al. reveal a hierarchy of timescales in mouse behavior, including low-level syllables and high-level behavioral states. States and syllables are encoded in different brain areas. Prefrontal...

Sexual selection acts on heritable differences within species, driving the parallel diversification of signal production in one sex and behavioral res…

Sam Wang, a neuroscientist running for the U.S. House of Representatives, has been interested in “fixing bugs in democracy” for decades.