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Philipp Brand

@pbrand.bsky.social
1.1K followers 1.2K following 88 posts

PI of Evolutionary Neuroscience and Behavior Group at the Max Planck Institute for Brain Research. Evolution of behavior, neural circuits, chemical senses, and speciation. he/him brain.mpg.de/brand

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Reposted by Philipp Brand
Leah Houri-Zeevi @leahhouri.bsky.social · 25/09/2026
🩸🩸🩸TODAY WE SHARE TWO MAJOR DISCOVERIES🩸🩸🩸 1. We peered into genomes and brains of the rare mosquitoes that QUIT feeding on blood and found what biting is built from 2. Humans got rid of isoleucine in their blood, malaria suffers from it, and mosquito proteomes budget for it THREADS>
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Stephen Montgomery @ebablab.bsky.social · 15/09/2026
Are you a #NewPI in Ecology & Evolution? Would you like to meet with peers to chat about work, the future and life as a new PI? 🍪☕️ Then I have the form for you! 📋 Help us gauge interest in a new network/event by filling in this short survey: forms.cloud.microsoft/e/K4wUiuLuFn Please RT! 🙏
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Philipp Brand @pbrand.bsky.social · 01/09/2026
We are looking for a research assistant to join our team. brain.mpg.de/brand Apply using the link below if you are interested in doing research on the neural and genetic underpinnings of behavioral evolution. jobs.brain.mpg.de/jobposting/6...
Description of job ad for Research Assistant in the lab of Evolutionary Neuroscience and Behavior Lab at the Max Planck Institute for Brain Research.Description of job ad for Research Assistant in the lab of Evolutionary Neuroscience and Behavior Lab at the Max Planck Institute for Brain Research.
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Alexis Stamatakis @stamatak.bsky.social · 12/09/2026
The RAxML-NG v2.0 preprint is out: www.biorxiv.org/content/10.6... v2.0 features integrated model testing, fast branch support metrics, automatic parallelization, phylogenetic difficulty prediction, genotype evolution models, to name but the most important features. And it is A LOT FASTER of course
biorxiv.org
RAxML-NG 2: Automatic model selection, novel tree search heuristics, and fast branch support metrics
RAxML-NG is a widely used tool for maximum likelihood based phylogenetic inference. In the seven years since the last RAxML-NG publication, we have continuously improved and extended the code. Here, w...
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Philipp Brand @pbrand.bsky.social · 03/09/2026
We're about to start an exciting new project with generous support from the @erc.europa.eu In SIMBIO, we want to know how bacterial endosymbionts modify neurons on the genetic and functional level and how this shapes the evolution of their host's mating behavior.
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Max Farnworth @maxfarnworth.bsky.social · 31/08/2026
🚨 I AM HIRING a 3-year postdoc & 4-year PhD student 🚨 [PLEASE SHARE WIDELY] My Emmy Noether @dfg.de funded Neural Circuit & Systems Evolution lab (🌟) at the @unimainz.bsky.socialÍ wants to start existing. So..., what do we need? WELL... we need you! APPLY UNTIL 21 SEPTEMBER.
static.klipy.com
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Philipp Brand @pbrand.bsky.social · 01/09/2026
We are looking for a research assistant to join our team. brain.mpg.de/brand Apply using the link below if you are interested in doing research on the neural and genetic underpinnings of behavioral evolution. jobs.brain.mpg.de/jobposting/6...
Description of job ad for Research Assistant in the lab of Evolutionary Neuroscience and Behavior Lab at the Max Planck Institute for Brain Research.Description of job ad for Research Assistant in the lab of Evolutionary Neuroscience and Behavior Lab at the Max Planck Institute for Brain Research.
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Mohammed Khallaf @khallaf.bsky.social · 15/07/2026
Our new paper is out in @nature.com! We uncovered how a naked mole-rat queen 👑 controls an entire colony: a natural contraceptive scent that suppresses reproduction in other females! A remarkable mammalian parallel to bees and ants! 🐝🐜 @garyrlewin.bsky.social youtu.be/enfv3zJrWKM?...
youtu.be
Naked mole-rats are ruled by a queen: this chemical puts her in power
YouTube video by nature video
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European Drosophila Society @fly-eds.bsky.social · 13/07/2026
📣 📣 📣 📣 To all Drosophilists: the call for Workshop proposals at the 2027 European Drosophila Research Conference in Bonn (20-23 September 2027) is OPEN! Go to link below for instructions. Closing date: 30 September 2026. 👇🏻👇🏻👇🏻 tinyurl.com/45y8trzd
The image is the logo of the 2027 European Drosophila Research Conference in Bonn, Germany: an adult male fly overlaid on a view of Bonn city.
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Jason Shepherd @jasonsynaptic.bsky.social · 29/06/2026
Very excited for our new paper, now out in @cellcellpress.bsky.social! /🧵 The protein Tau forms intracellular toxic tangles in neurons in Alzheimer’s disease and Tauopathies. Tau pathology slowly spreads from cell-to-cell but the mechanisms are not clear /1 authors.elsevier.com/sd/article/S...
authors.elsevier.com
Arc mediates intercellular tau transmission via extracellular vesicles
Tau pathology spreads cell to cell, but the mechanisms of intercellular tau transmission remain unclear. We find that the neuronal gene Arc is critica…
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Ben Hopkins @brhopkins92.bsky.social · 06/03/2026
Quick plug for our new resource, the Drosophila Species Stock Exchange. This is a database and mailing list that documents species currently in culture and the labs holding them. If you want to know more or sign up then please get in touch. See attached for more info and please share!
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Jenny Tung @jennytung.bsky.social · 05/03/2026
Leipzig U and the MPI for Evolutionary Anthropology (MPI-EVA) have an open faculty position (W2) in evolutionary population genetics! This position is tenured and comes with generous core funding. We are eager to welcome a new colleague! Deadline March 11. www.uni-leipzig.de/en/newsdetai...
uni-leipzig.de
Professorship in population genetics in the field of evolutionary anthropology and medicine (W2)
Faculties & Facilities
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Philipp Brand @pbrand.bsky.social · 27/02/2026
@annaryba.bsky.social's paper on the neural underpinnings of intraspecific behavioral variation is now out in @currentbiology.bsky.social Highly recommend! -> Paper identifies neural substrate for variation in promiscuity among Drosophila melanogaster strains🧪 www.sciencedirect.com/science/arti...
sciencedirect.com
Strain variation identifies a neural substrate for behavioral evolution in Drosophila
Sexual selection acts on heritable differences within species, driving the parallel diversification of signal production in one sex and behavioral res…
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Jeffrey Ross-Ibarra @jrossibarra.bsky.social · 09/02/2026
Fun news! @gcbias.bsky.social and I are teaching a 2-week online population genetics workshop this summer to raise money for the Center for Population Biology at UC Davis. We're trying to gauge interest -- please fill this out if you might be interested! And please share broadly!
docs.google.com
Davis Summer Population Genomics Program
Want to learn population genetics? Please fill out this form to indicate your potential interest in a 2-week intensive online summer population genetics course taught by Jeffrey Ross-Ibarra and Graham...
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Tobias Ackels @tobiasackels.bsky.social · 01/02/2026
Postdoc position in systems neuroscience! Excited to recruit a postdoc for my lab at the University of Bonn. 🔬 In vivo physiology (Neuropixels, 2P/miniscope) 🐭 Head-fixed & freely moving behaviour 💡 Optogenetics/chemogenetics ⏳ Start: ASAP | Application deadline: 28.02.2026 More info below ⬇️
The research group “Sensory Dynamics and Behaviour” of Prof. Dr. Tobias Ackels at the Institute of Experimental Epilepsy and Cognition Research at the
University Hospital Bonn invites applications for a position as:
Postdoctoral Researcher (m/f/d)
The position is initially limited to three years (TV-L E13/100%),
starting from April 2026 or as soon as possible.
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James Lightfoot @jameslightfoot.bsky.social · 21/01/2026
Why do some worms graze on bacteria while others hunt and kill? Our study, published today in Nature, reveals how predatory aggression evolved in nematodes. Led by @gunizgozeeren.bsky.social and @leoboeger.bsky.social across the @jameslightfoot.bsky.social and @monikakscholz.bsky.social labs.
nature.com
Predatory aggression evolved through adaptations to noradrenergic circuits - Nature
Noradrenergic circuits support and balance aggressive behavioural states in predatory nematodes, distinguish predatory from non-predatory nematode species and are associated with the evolution of comp...
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The Rockefeller University @rockefeller.edu · 15/01/2026
A study in @science.org from Paul Cohen's lab, led by @maschakoenen.bsky.social, demonstrates how beige fat directly influences blood pressure. The findings offer a new target for treating vascular disease and could lead to more precise therapies for hypertension: bit.ly/4pK0hGh
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Sachin Sethi @sethisachin.bsky.social · 06/01/2026
www.cell.com/cell/fulltex... We had a lot of fun working on this project (led by Itzel Ishida, not on bluesky). Some interesting highlights from the paper -
cell.com
Neuronal calcium spikes enable vector inversion in the Drosophila brain
In the fly central complex, PFNa neurons switch from firing classical sodium spikes when depolarized to firing non-canonical T-type calcium spikes when hyperpolarized. This bidirectional spiking allow...
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Hannah Haberkern @hannah-haberkern.bsky.social · 23/12/2025
📢 Join us, the Haberkern lab, @uni-wuerzburg.de for a postdoc studying neural circuit mechanisms of navigation. You’ll spearheading neurophysiology experiments on our brand new 2P! ⏳ Apply by 28th February 2026 Details: www.haberkernlab.de/docs/ENPostd... #neuroscience #academicjobs #postdoc
On the left, the image shows a schematic of a fly head, ring neurons and EPG neurons together with some calcium imaging frames. On the right is a photo of a fly on a ball in virtual reality and another schematic of a VR system.
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Richard Gao @rdgao.bsky.social · 03/12/2025
Finally got the job ad—looking for 2 PhD students to start spring next year: www.gao-unit.com/join-us/ If comp neuro, ML, and AI4Neuro is your thing, or you just nerd out over brain recordings, apply! I'm at neurips. DM me here / on the conference app or email if you want to meet 🏖️🌮
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Enrico Bertolini @enriberti.bsky.social · 27/11/2025
My main postdoc work is now out :) In the group of @tomtom-auer.bsky.social with Justine Pascual, @bruzz-1.bsky.social , Noemi Sgammeglia , with crucial collaboration with @dahaniel.muench.bio and @ribeirocarlitos.bsky.social www.nature.com/articles/s41...
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Jacopo Razzauti @jacoporazzauti.bsky.social · 19/11/2025
Our preprint is out! www.biorxiv.org/content/10.1... Peter Skovorodnikov and I are excited to present FERAL: a new video-understanding toolkit that maps raw video directly to behavior, no pose estimation required. It works across species, from lab to field, and even in collective systems. (🧵1/n)
biorxiv.org
FERAL: A Video-Understanding System for Direct Video-to-Behavior Mapping
Animal behavior unfolds continuously in time, yet quantitative analyses often require segmenting it into discrete, interpretable states. Although manual annotation can achieve this, it remains slow, s...
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Philipp Brand @pbrand.bsky.social · 17/11/2025
@rorycoleman.bsky.social and I wrote an opinion piece called 'From neurons to novelty: Circuit mechanisms shaping courtship evolution' We argue that now is a great time for neuro-evo research www.sciencedirect.com/science/arti...
sciencedirect.com
From neurons to novelty: Circuit mechanisms shaping courtship evolution
The vast diversity of animal behaviors has long inspired ethologists and neuroscientists, but circuit mechanisms driving this variation remain elusive…
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MPI for Biological Intelligence @mpiforbi.bsky.social · 19/09/2025
Apply now to become a speaker at our Institute! We invite excellent postdocs in neuroscience, ecology and other fields related to our research to apply for our Emerging Scientist Talk Series. Apply by October 24: www.bi.mpg.de/ess @chr-mayer.bsky.social @fleyes.bsky.social @michaelahau.bsky.social
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Mario Vallejo-Marin @nicrodemo.bsky.social · 24/10/2025
Do you want to do a Masters in Evolutionary Biology? The call for applying to the MEME program is now open! MEME is a fantastic 2-year MSc between four European Universities on all areas of Evolutionary Biology. Apply and study in Sweden/France/the Netherlands/Germany/USA/Switzerland! www.evobio.eu
Picture of MEME students on the beach
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Yuki Haba @yukihaba.bsky.social · 25/10/2025
How does life evolve to adapt to modern cities? Out now in Science, my PhD work with @lindymcbr.bsky.social uncovers the ancient origin of the “London Underground mosquito” – one of the most iconic examples of urban adaptation. 🧵(1/n) @science.org www.science.org/doi/10.1126/science.ady4515
science.org
Ancient origin of an urban underground mosquito
Understanding how life is adapting to urban environments represents an important challenge in evolutionary biology. In this work, we investigate a widely cited example of urban adaptation, Culex pipie...
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Kelsey Tyssowski @kelseytea.bsky.social · 22/10/2025
🧠🌟🐭 Excited to share some of my postdoc work on the evolution of dexterity! We compared deer mice evolved in forest vs prairie habitats. We found that forest mice have: (1) more corticospinal neurons (CSNs) (2) better hand dexterity (3) more dexterous climbing, which is linked to CSN number🧵
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Matthew Cobb @matthewcobb.bsky.social · 17/10/2025
People thought I was bonkers studying courtship and mating in Drosophila erecta nearly 50 years ago. Sometimes you just have to wait.
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Philipp Brand @pbrand.bsky.social · 17/10/2025
Our new paper would not have been possible without a brilliant team! Huge thanks to Katie Keller, @rorycoleman.bsky.social, @noelleeghbali.bsky.social, Sarah Zylka, @neuroluci.bsky.social 🪰🧪✨ Especially grateful for guidance and inspiration by my mentor Vanessa Ruta www.biorxiv.org/content/10.1...
biorxiv.org
Ecological cues orchestrate concerted courtship in a Drosophila host specialist
Mating decisions are often attributed to the sensory signaling between prospective sexual partners. Yet these interactions are also shaped by the broader environmental context in which they unfold, to...
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Philipp Brand @pbrand.bsky.social · 16/10/2025
Excited to share our new #biorxivpreprint We discovered that the fruit fly #drosophila erecta requires food odor to mate and arousal is further enhanced by social group motion. Cross-species analysis of brain activity reveals a novel gate evolved from within a conserved circuit shorturl.at/gGYm7
a group of Drosophila erecta fruit flies on a small food patch. flies on white background
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Oded Rechavi @odedrechavi.bsky.social · 15/10/2025
BIG ANNOUNCEMENT📣: I haven’t been this excited to be part of something new in 15 years… Thrilled to reveal the passion project I’ve been working on for the past year and a half!🙀🥳 (thread 👇)
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Greg Jefferis @jefferis.bsky.social · 15/10/2025
Excited to share our new #biorxivpreprint: “Sexual dimorphism in the complete connectome of the Drosophila male central nervous system” www.biorxiv.org/content/10.1... We describe the #connectomics reconstruction and analysis of an entire adult #maleCNS #drosophila central nervous system. 1/10
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Janelia FlyEM @janelia-flyem.bsky.social · 05/10/2025
We're very proud to be releasing the complete male fly CNS connectome! It's the product of a huge team effort here at Janelia in partnership with the Cambridge Fly Connectomics group (@jefferis.bsky.social and colleagues), plus invaluable collaborators. More soon... www.janelia.org/project-team...
janelia.org
Male CNS Connectome
A team of researchers has unveiled the complete connectome of a male fruit fly central nervous system —a seamless map of all the neurons in the brain and nerve cord of a single male fruit fly and the ...
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Ben Williamson @benpatrickwill.bsky.social · 07/09/2025
Academic authors, here's a peek into the black box of journal publishing from an journal editor if you can bear it:
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Daniel Kronauer @danielkronauer.bsky.social · 21/08/2025
If you’re interested in ants, olfaction, gene regulation, or all of the above, here’s a new preprint from the lab for you. It describes an unorthodox mechanism of transcriptional interference by which ant olfactory sensory neurons produce a single functional receptor. www.biorxiv.org/content/10.1...
biorxiv.org
Transcriptional Interference Gates Monogenic Odorant Receptor Expression in Ants
Communication is crucial to social life, and in ants, it is mediated primarily through olfaction. Ants have more odorant receptor (OR) genes than any other group of insects, generated through tandem d...
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Greg Jefferis @jefferis.bsky.social · 21/08/2025
Neuronal diversity is written in transcriptional codes 🧬. But what is the logic of these codes that define cell types and wiring patterns? To find out we built a #scRNAseq developmental atlas of the Drosophila nerve cord and linked it to the #connectome 🪰🧠 #preprint thread ⬇️1/8
ALT text: A UMAP representation of a single cell RNAseq dataset from the Drosophila ventral nerve cord as well as images of the Drosophila nerve cord connectome and different stages of fly development.
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Philipp Brand @pbrand.bsky.social · 21/08/2025
Exciting new Ruta lab preprint by @annaryba.bsky.social et al. on the neural underpinnings of intraspecific behavioral variation: Strain variation identifies a neural substrate for behavioral evolution Drosophila www.biorxiv.org/content/10.1...
biorxiv.org
Strain variation identifies a neural substrate for behavioral evolution in Drosophila
Sexual selection acts on heritable differences within species, driving the parallel diversification of signal production in one sex and behavioral responses in the other. This coevolution implies that...
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Ralph Emilio Peterson @ralphpeterson.bsky.social · 25/07/2025
New preprint!

 tl;dr — We ran around late at night to record wild rats in NYC and figured out how to quantify their behavior and environment. 🧵 w/ Dima Batenkov, @zamakany.bsky.social, Emily Mackevicius www.biorxiv.org/content/10.1...
biorxiv.org
Computational Urban Ecology of New York City Rats
Urban rats are highly adaptable, thriving in the dynamic and often inhospitable conditions of modern cities. Despite substantial mitigation efforts, they remain an enduring presence in urban environme...
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Felix Baier @felixbaier.bsky.social · 23/07/2025
🚨Very happy that my PhD work is now out in @nature.com! We discovered that evolution, by acting in the midbrain, shifted the threshold to escape in Peromyscus mice, to fine-tune defensive strategies in different environments www.nature.com/articles/s41... This was a truly collaborative effort! 🧵⬇️
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Lucia Prieto Godino @neuroluci.bsky.social · 12/06/2025
How do brain circuits evolve? We started looking for some answers by using synapse-resolution cross-species comparative connectomics on an entire olfactory circuit 👇 bit.ly/44aVm9E
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Genetics Society of America @genetics-gsa.bsky.social · 05/05/2025
🏅 Congrats to 2025 GSA Medal recipient @nkwhiteman.bsky.social (@ucberkeleyofficial.bsky.social)! His research reveals how plants and herbivores co-evolve through chemical warfare. Read more about his career & research: buff.ly/mxnPQon
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Max Farnworth @maxfarnworth.bsky.social · 07/05/2025
Really happy to share our new preprint on the central complex of Heliconiini butterflies www.biorxiv.org/content/10.1.... Check it out! @neuroethology.org @brainevolutionnews.bsky.social @prelights.bsky.social @tibbe-evolneuro.bsky.social #brainevolution #heliconius #centralcomplex
biorxiv.org
Distinct evolutionary trajectories of two integration centres, the central complex and mushroom bodies, across Heliconiini butterflies
Neural circuits have evolved to produce cognitive processes that facilitate a species variable behavioural repertoire. Underlying this variation are evolutionary forces, such as selection, that operat...
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Graham Coop @gcbias.bsky.social · 24/04/2025
I'm honoured to have been elected as a member of the American Academy of Arts and Sciences. It's a wonderful recognition of all the hard work by the amazing folks in the lab over the years. A huge thanks to them all.
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Daniel Münch @dahaniel.muench.bio · 10/04/2025
🚀 I’m thrilled to announce I’ve started a tenure track position as Professor for Animal Neurophysiology at @jlugiessen.bsky.social As of April 1, the Münch Lab is open! 🔬🧠🪰 We’ll study chemosensory processing, multisensory integration & feeding in flies. 🎓 PhD position coming soon, stay tuned!
media.tenor.com
a large group of people are sitting in a lecture hall with a sign that says cbs on it
ALT: a large group of people are sitting in a lecture hall with a sign that says cbs on it
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Marcus Stensmyr @marcusstensmyr.bsky.social · 07/04/2025
We are looking for a PhD student! If you are interested in Drosophilids, systematics, bioinformatics, fiddling with museum specimens of old/weird flies, and chemosensation, then maybe this is for you! Please rebutterfly(?)! Apply below. lu.varbi.com/en/what:job/...
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Philipp Brand @pbrand.bsky.social · 20/03/2025
Proud that one of my photographs has made the cover of Cell. (first 'official' photograph publication) Very happy to contribute the pic and highlight the latest publication of the Ruta lab.
Macrophotography of a pink flower in the center on a green background. Three Drosophila flies are on the flower, two of which interact with one another
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Michelle Stitzer @mcstitzer.bsky.social · 27/01/2025
New preprint featuring my favorite maize-relatives, the Andropogoneae! We sequenced the genomes of 27 species, including lemongrass, kangaroo grass, little and big bluestem, and more -- key species that shape grasslands and prairies worldwide. www.biorxiv.org/content/10.1...
On top, five Andropogoneae grass species, from left to right Zea mays subsp. mays, Hemarthria uncinata, Miscanthus sinensis, Sorghum bicolor, Andropogon gerardi. On bottom, a map of the world, with collection sites of Andropogoneae grasses in points. A green background shows the distribution of Andropogoneae grasses throughout tropical and temperate latitudesOn left, a phylogeny of Andropogoneae species, with 14 independent polyploidy origins noted. On right, genome size and repeat content of each assembly. Across all assemblies, average assembly size is 1.9 Gb, and average repeat size is 1.5 Gb.
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