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Athena Akrami

@athenaakrami.bsky.social
1.5K followers 354 following 160 posts

Neuroscientist at The Sainsbury Wellcome Centre, UCL, in London. Leading the "Learning, Inference & Memory" laboratory. Accidental advocate of #longcovid www.lim.bio

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Athena Akrami @athenaakrami.bsky.social · 26/09/2026
Now accepted at #NeurIPS2026 🎉 aab, ccd & eef share a pattern, regardless of the specific elements. How RNNs build abstract representations of sequence structure? Led by Vezha Boboeva, who is on the faculty job market now. If you're hiring in comp/systems neuro, she's exactly who you want!
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Masahiro Nakano @masahironakano.bsky.social · 19/09/2026
My first paper has been published in Hippocampus! bsky.app/profile/masa... Thank you Caswell and Claudia for your support!
bsky.app
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Mariam Aly @mariamaly.bsky.social · 15/09/2026
How do keep a narrative active in our mind despite interruptions? The default mode network can maintain a representation of an interrupted story over a delay, even when the delay is filled with a demanding task. This representation is strikingly transformed from the initial experience!
biorxiv.org
Cortical and Hippocampal Pathways to Mental Continuity
How do people preserve mental continuity when tasks are interrupted? One established pathway runs through the hippocampus, which stores snapshots of our mental context for later reinstatement. We prop...
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Terence Tao @teorth.bsky.social · 11/09/2026
A group of 25 Fields Medalists, including myself, have made a joint declaration on Math and AI: mathandai.org . We welcome additional signatories. See also this article in the Economist announcing the declaration: www.economist.com/science-and-...
mathandai.org
Declaration — Math and AI
Read the declaration and add your name.
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Athena Akrami @athenaakrami.bsky.social · 07/09/2026
Another bittersweet moment; another PhD student graduated. Huge congratulations to Dr. Quentin Pajot-Moric, who just passed his viva! 🥳🎉 And big thanks to the examiners @kerrywalker.bsky.social and @adilgkhan.bsky.social! 🙏 ❤️
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Jieyu Zheng @jieyusz.bsky.social · 04/09/2026
How fast can mice learn complex mazes? With @mameister4.bsky.social we reveal memory, generalization, latent learning, and remote credit assignment of mice in the Manhattan Maze. Do mice born without a cortex or hippocampus have them too? Check it out! www.biorxiv.org/content/10.6...
biorxiv.org
Rapid spatial cognition in mice, with and without neocortex and hippocampus
Rapid learning, memory, and generalization are often attributed to circuits of the neocortex and hippocampus, but their specific role remains unclear. To examine these cognitive abilities together in ...
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Sainsbury Wellcome Centre @sainsburywellcome.bsky.social · 13/08/2026
Congratulations to the winners of the SWC Emerging Neuroscientists Seminar Series 2026/27! 🎉 • Lucas Tian, Rockefeller University • @matteoguardamagna.bsky.social, Kavli Institute for Systems Neuroscience • @albarran.bsky.social, Columbia University • Krithika Mohan, University of California
sainsburywellcome.org
Emerging Neuroscientists Seminar Series 2026/27 winners announced | Sainsbury Wellcome Centre
The Sainsbury Wellcome Centre is delighted to announce the winners of our 2026/27 Emerging Neuroscientists Seminar Series (ENSS). The prestigious ENSS competition spotlights aspiring leaders who are a...
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Helen Barron @helencbarron.bsky.social · 28/07/2026
***New preprint from the lab*** showing “Generative replay across hippocampal-neocortical circuits”. In sleep we show spiking sequences in V1 (sensory neocortex!) that represent information that has not been directly experienced www.biorxiv.org/content/10.6... @bndu.ox.ac.uk @ndcnoxford.bsky.social
biorxiv.org
Generative replay across hippocampal-neocortical circuits
To make flexible decisions, the brain needs to make inferences between events that were not directly experienced together. In sharp-wave ripple (SWR) events, during periods of rest and sleep, spiking ...
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Reza Shadmehr @rezashadmehr.bsky.social · 28/07/2026
If an action results in error, each neuron requires an individualized teaching signal that guides change in its output. This is the credit assignment problem of learning. Are there neurons in the brain that can compute such a sophisticated teaching signal? Yes. www.biorxiv.org/content/10.6...
biorxiv.org
Climbing fibers encode the gradient of a loss function for the cerebellum
Neurons in the brain are often many synapses away from motoneurons, yet if a movement results in error, each distant neuron needs a teacher that considers its specific contribution to production of th...
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Sainsbury Wellcome Centre @sainsburywellcome.bsky.social · 08/06/2026
SWC & @gatsbyucl.bsky.social are looking to sponsor early career researchers in mechanistic theories of neural computation for external fellowships. Join a collaborative, world-class community at the interface of theory and experiment. Apply by 16 July www.sainsburywellcome.org/content/fell...
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AntonioFR @antferrui.bsky.social · 06/07/2026
Our work on goal-directed theta sweeps is out! We found two different types of theta sweeps in the rat hippocampus. During random foraging, left-right alternating sweeps dominated (Vollan, 25). However, during memory-guided navigation sweeps pointing to hidden goal locations emerged with learning.
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Athena Akrami @athenaakrami.bsky.social · 06/07/2026
The lab is at @fens.org, with 5 posters — spatial & auditory working memory, prefrontal decision-making, dopamine in statistical learning, and a 2-photon rat-brain atlas for BrainGlobe. Unfortunately, I couldn't make it this year, but come find the rest of the lab on Tue, Thurs, & Fri! #FENS2026
Flyer — LIM Lab (Akrami Lab, Sainsbury Wellcome Centre / UCL) posters at FENS Forum 2026, Barcelona, 6–10 July. Tue 7 July board 129 (Arpit Agarwal); Thu 9 July boards 639 (Audra Rybak), 641 (Kyunghye Lee), 022 (Viktor Plattner); Fri 10 July board 353 (Lida Pentousi).
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Neil Burgess @neilburgess10.bsky.social · 01/07/2026
Ever wondered how the hippocampal cognitive map is read-out? @changmin-yu.bsky.social @zilong-ji.bsky.social with Jake & John, show that, during navigation, theta sweeps indicate remembered goal-directions (cf. current/next movements or perceptual targets) 1/2 www.nature.com/articles/s41...
Decoded locations from place cell firing sweep towards a remembered goal location during each theta cycle irrespective of the current movement or head direction
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Hugo Spiers @hugospiers.bsky.social · 25/06/2026
Learning shapes neural geometry in the primate prefrontal cortex www.nature.com/articles/s41...
nature.com
Learning shapes neural geometry in the primate prefrontal cortex - Nature Neuroscience
Learning transforms prefrontal cortex activity from flexible, high-dimensional representations into compact, task-relevant and abstract codes, enabling efficient generalization of learned rules to new...
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Michael Okun @michael-okun.bsky.social · 10/06/2026
I’ve officially resigned as Associate Editor for Frontiers in Systems Neuroscience. It used to be a reputable journal, but became a case study in how forced automation destroys academic integrity. 👇
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Sainsbury Wellcome Centre @sainsburywellcome.bsky.social · 08/06/2026
Know a brilliant postdoc in neuroscience? Encourage them to apply for the SWC Emerging Neuroscientists Seminar Series - a chance to present to the London neuroscience community. Travel and accommodation covered, no CV’s or references needed. www.sainsburywellcome.org/web/content/...
Quote from Dr Sonja Blumenstock, 2025 ENSS Speaker "It's really achieving what it's designed to do: give researchers a chance to connect, discuss ideas and exchange perspectives."
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Athena Akrami @athenaakrami.bsky.social · 04/06/2026
When I watched Persepolis in 2007, during my PhD in Italy, it felt as if someone had crawled inside my mind, read its deepest memories, griefs & longings, & put them on screen. Nothing about Iran has resonated w me like that since. Her family noted she “died of sadness” after losing her husband 😔💔
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Athena Akrami @athenaakrami.bsky.social · 23/05/2026
"Support academic institutions under attack" A short correspondence with @sepikeshavarzi.bsky.social and @roozbehkiani.bsky.social -- Defending academic life is not peripheral to the mission of science. It is part of it. www.nature.com/articles/d41...
nature.com
Support academic institutions under attack
Letter to the Editor
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Athena Akrami @athenaakrami.bsky.social · 22/05/2026
This is super cool! Monkeys' frontal cortex when drawing: action strokes exhibit 3 features indicating symbolic representation: 1.invariance over low-level motor parameters 2.categorical structure reflecting discrete action types 3.recombination into novel sequences www.nature.com/articles/s41...
nature.com
Neural representation of action symbols in primate frontal cortex - Nature
A drawing-like task designed to study compositional generalization identifies a specific neural population in the ventral premotor cortex in primates that encodes action symbols.
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Roxana Zeraati @roxana-zeraati.bsky.social · 21/05/2026
Some incredibly exciting news that still feels a bit surreal: I am starting my research group @mpicybernetics.bsky.social! The best part? We are hiring at all levels! Curious about the science we plan to tackle, read along :) #NeuroSky
An illustration of different species, from worms to humans, foraging, indicating the main topic of our research group.
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Sepiedeh Keshavarzi @sepikeshavarzi.bsky.social · 21/05/2026
Together with @roozbehkiani.bsky.social and @athenaakrami.bsky.social, we published a Nature correspondence highlighting our open letter’s core message: the academic community must speak out against attacks on academic institutions. doi.org/10.1038/d415... Open access version: rdcu.be/fju9B
doi.org
Support academic institutions under attack
Letter to the Editor
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Ben Hayden @benhayden.bsky.social · 06/05/2026
New paper from the lab! "Plasticity and language in the anaesthetized human hippocampus" www.nature.com/articles/s41...
nature.com
Plasticity and language in the anaesthetized human hippocampus - Nature
In the hippocampus, complex processing of sensory stimuli occurs even in the unconscious state.
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Athena Akrami @athenaakrami.bsky.social · 30/04/2026
This is incredibly sad. A huge pool of young, fierce talent-living through a 2-month internet blackout, a fragile ceasefire that could break at any moment, practically suspended university classes-turned away from Neuromatch, one of the most noble efforts to democratize education & bridge borders 😔😡
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ines-schoenmann.bsky.social @ines-schoenmann.bsky.social · 27/04/2026
New peer-reviewed paper w/ @mheilbron.bsky.social, @predictivebrain.bsky.social & Jakub Szewczyk! Pre-onset brain encoding has been taken as evidence that brains–like LLMs–predict upcoming words. We show that the same signatures arise in systems that cannot predict. (elifesciences.org) (1/8)
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Kenji Lee @kenjilee.bsky.social · 27/04/2026
Super excited to (finally!) show our work on identifying cell types! Now in press www.nature.com/articles/s41.... We show how to identify cell types from ephys recordings *without* optotagging. This opens the study of not just individual cell types, but the interacting neural circuit during behavior
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Sainsbury Wellcome Centre @sainsburywellcome.bsky.social · 20/04/2026
A migratory bird brain, the Eurasian blackcap, has been mapped for the first time using high-resolution light microscopy. The open-source software tools developed form a foundation for new brain atlases to be built for any species, providing a valuable resource.
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Blake Richards @tyrellturing.bsky.social · 15/04/2026
I think this is a super interesting paper from @markhisted.org and co: www.cell.com/neuron/abstr... My personal bet is that the phenomenon seen here would be different for some types of inter-laminar recurrence. #neuroscience 🧪
cell.com
Recurrent cortical networks encode natural sensory statistics via sequence filtering
The visual cortex receives a stream of high-dimensional sensory input. The role of dense local, recurrent cortical connections in shaping responses to these inputs has been unclear. Here, we show that...
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Georg Keller @georgkeller.bsky.social · 15/04/2026
For nearly a century, we believed the therapeutic effect of ECT is the seizure. Our latest research suggests we may have been looking at the wrong event. A thread on why cortical spreading depression (CSD) might be the driver of therapeutic benefit. Work led by @therehugolad.bsky.social
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Matteo Carandini @carandinilab.net · 15/04/2026
Going from neural activity to blood flow just became easier! Two brainwide populations, each with its neurovascular coupling. (But going backwards... is now a tad more complicated.) By @agnesland.bsky.social & team. Thanks @intlbrainlab.bsky.social @wellcometrust.bsky.social @simonsfoundation.org
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Christos Constantinidis @cconstan.bsky.social · 15/04/2026
Very excited to announce that my textbook on “Working Memory” is now available for pre-order! shop.elsevier.com/books/workin... A few thoughts
shop.elsevier.com
Working Memory
Working Memory provides a comprehensive examination of the neural basis of working memory, defined as the cognitive ability to maintain information ov
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Athena Akrami @athenaakrami.bsky.social · 13/04/2026
New preprint! 🧠 How do RNNs learn abstract rules from sequences, independent of specific stimuli? By Vezha Boboeva, with Alberto Pezzotta & George Dimitriadis "From sequences to schemas: low-rank recurrent dynamics underlie abstract relational representations" www.biorxiv.org/content/10.6...
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Jeremiah Cohen @jeremiahycohen.bsky.social · 13/04/2026
Delighted to share our discoveries about one of the brain's neurotransmitter systems: www.biorxiv.org/content/10.6... Together with colleagues at the @alleninstitute.org, we have learned a lot about a tiny cluster of neurons in the brainstem locus coeruleus (LC) that releases norepinephrine (NE). 1
biorxiv.org
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Sepiedeh Keshavarzi @sepikeshavarzi.bsky.social · 07/04/2026
When universities and research institutions become military targets, academics cannot remain silent. I co-initiated an open letter calling for global academic solidarity and support for affected students and scholars. Please share. to read and sign: sites.google.com/view/protect...
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Athena Akrami @athenaakrami.bsky.social · 07/04/2026
Academic friends, It's beyond heartbreaking to watch what's unfolding in Iran & the region. A few of us drafted an open letter calling for protection of civilians & of educational, research, medical & cultural institutions. Please read & sign if you agree: sites.google.com/view/protect... #IranWar
sites.google.com
Protect Academic Life in Iran
We, the undersigned academics and researchers from around the world, express our profound concern over recent military strikes on Iran, the retaliatory responses, and the reported impact on civilian l...
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Amirreza Bahramani @amir137.bsky.social · 06/04/2026
Last night, US/Israeli strikes bombed Sharif University, my alma mater, heavily damaging the IT Center, Philosophy of Science building, EE, and more. Trump spoke of sending Iran "back to the Stone Age." That is the goal of this war. Scientists worldwide should speak up against these atrocities.
Philosophy of Science GroupElectrical Engineering DepartmentI think this is a part of the civil engineering department.
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Joao Barbosa @jbarbosa.org · 03/04/2026
Wanna do neuroscience in Paris but can't find interesting lab? Want to come do a sabbatical but don't know who to collaborate? Check this webpage aggregating ~all the neuroscience labs (+200) in Paris. ⚠️only the information of 'verified' profiles is reliable⚠️ Please retweet 🙏 parisneuro.fr
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Athena Akrami @athenaakrami.bsky.social · 02/04/2026
Pasteur Institute of Iran, founded in 1920 now destroyed by Israel-US bombing😞 It played a pivotal role in developing vaccines & public health services, for over a century, now gone😞 A few days ago a pharmaceutical plant was bombed, accused of making anesthetic fentanyl #War #PasteurInstituteIran
Rubble and ruins -- Iran Pasteur Institute in Tehran, bombed by US-IsrealRubble and ruins -- Iran Pasteur Institute in Tehran, bombed by US-IsrealRubble and ruins -- Iran Pasteur Institute in Tehran, bombed by US-IsrealRubble and ruins -- Iran Pasteur Institute in Tehran, bombed by US-Isreal
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Katharina Schmack @kathaschmack.bsky.social · 31/03/2026
🥁🎉The Psychosis Collective proudly presents our first preprint 𝐂𝐥𝐨𝐳𝐚𝐩𝐢𝐧𝐞 𝐬𝐮𝐩𝐩𝐫𝐞𝐬𝐬𝐞𝐬 𝐚𝐮𝐭𝐨𝐢𝐦𝐦𝐮𝐧𝐢𝐭𝐲 𝐝𝐫𝐢𝐯𝐢𝐧𝐠 𝐩𝐬𝐲𝐜𝐡𝐨𝐬𝐢𝐬-𝐥𝐢𝐤𝐞 𝐛𝐞𝐡𝐚𝐯𝐢𝐨𝐮𝐫 𝐢𝐧 𝐦𝐢𝐜𝐞 𝘈 𝘥𝘪𝘴𝘤𝘰𝘷𝘦𝘳𝘺 𝘫𝘰𝘶𝘳𝘯𝘦𝘺 𝘪𝘯 𝘵𝘩𝘳𝘦𝘦 𝘢𝘤𝘵𝘴 starring Le He & Harriet Feldman www.biorxiv.org/content/10.6... We wanted to understand how antipsychotics work. Thread🧵
Graphical abstract showing that NMDAR immunisation drives psychosis-like behaviour in mice, while clozapine reverses this. Upper panel: arrows show NMDAR immunisation producing a mouse exhibiting psychosis-like behaviour, with clozapine reversing this effect. Lower panels: anti-NMDAR antibodies bind neuronal NMDA receptors, which are then eliminated by microglia via phagocytosis, leading to psychosis. Clozapine restores NMDA receptor levels by reducing anti-NMDAR antibody levels, consistent with an immunomodulatory mechanism of action.
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Constantinople lab @constantinoplelab.bsky.social · 25/03/2026
Thrilled to share our new paper, which shows that the relative timing of cholinergic and dopamine release dynamically gates whether dopamine acts as an RPE for in vivo plasticity and reinforcement learning. www.nature.com/articles/s41...
nature.com
Acetylcholine demixes heterogeneous dopamine signals for learning and moving
Nature Neuroscience - Jang et al. measured dopamine and acetylcholine release in the striatum of rats performing a decision-making task and found that the relative timing of cholinergic and...
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Athena Akrami @athenaakrami.bsky.social · 21/03/2026
More than any other time, this year it feels like we have to mark Nowruz. This year we welcome Spring with heavy hearts, but we still welcome it. May the turning of the season remind us that nothing stays frozen forever. With hope for peace, freedom, sanity & justice - Happy Spring, happy Nowruz🌱🪻
A Haft-Seen Nowruz display on a small round table by a window
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Marlene Cohen @marlenecohen.bsky.social · 20/03/2026
New preprint: our lab’s first Alzheimer’s paper! “Loss of neuronal population organization links pathology to behavior in a model of Alzheimer's disease” www.biorxiv.org/content/10.6... 🧪🧵1/
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Athena Akrami @athenaakrami.bsky.social · 15/03/2026
A heartbreaking message from a brilliant med student in Iran, determined to pursue neuroscience. She graduated only one week before the war started and now is volunteering to care for the injured. What would you tell her? (Part #4, especially). Please share your thoughts and comments. #IranWar
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Athena Akrami @athenaakrami.bsky.social · 14/03/2026
Happening now! If you want to know more about our recent preprint on unsupervised learning of abstract auditory sequences (decoupled from any reward) in hippocampus, go talk to Dammy! #cosyne2026
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Athena Akrami @athenaakrami.bsky.social · 13/03/2026
“In Iran, the black rain probably contains pollutants from the burning of heavy fuel, says Kastury. This could include cancer-causing benzene, acetone, toluene and methylene chloride, she adds.” ‘Black rain’ in Tehran — what are the health effects? www.nature.com/articles/d41...
nature.com
‘Black rain’ in Tehran — what are the health effects?
Toxic smoke from burning oil depots has blanketed Iran’s capital following missile strikes.
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Athena Akrami @athenaakrami.bsky.social · 13/03/2026
Today (now) poster session Go talk to Kira, who'll tell you 'all you need is serial bias to explain well known anti-cardinal biases in orientation working memory recall tasks' ‐ it's not efficient coding as thought before, but interesting serial biases formed by hierarchical complex representations
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Athena Akrami @athenaakrami.bsky.social · 12/03/2026
At @cosynemeeting.bsky.social? Come see some of our works! Tonight (March 12): [1-050] From sequences to schemas: How recurrent neural networks learn temporal abstractions 20:30 – 23:30 Pavilion 1 (I will present on behalf of the lead author Vizhe Boboeva, who is on maternity leave) #cosyne2026
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Matteo Guardamagna @matteoguardamagna.bsky.social · 11/03/2026
1/7 🧠 My journey into development begins with this work and question: how does the brain's spatial navigation system develop? We found that the neural networks for spatial navigation (tori and rings) are preconfigured and only later anchor gradually to the world with experience! 🧵
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Athena Akrami @athenaakrami.bsky.social · 11/03/2026
Very happy to share our review on Reinforcement Learning vs Statistical Learning, with @ambrafer.bsky.social and @predictivebrain.bsky.social: www.sciencedirect.com/science/arti... A nice summary: www.sainsburywellcome.org/blog/two-eng...
sciencedirect.com
Where learning paths meet: Convergence and divergence of statistical and reinforcement learning
Learning enables organisms to adapt to a dynamic world by forming and updating internal representations of their environment. Statistical Learning (SL…
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Athena Akrami @athenaakrami.bsky.social · 10/03/2026
Thanks @natmesanash.bsky.social for covering our new work, in @thetransmitter.bsky.social!
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