iiinova — where your digital self keeps evolving

Reposted by Benjamin Schuster-Böckler

Yun S. Song @yun-s-song.bsky.social · 23/09/2026

Please help spread the word! We are recruiting multiple Postdoctoral Fellows as part of the recently launched Bakar Computational Biomedicine Initiative (BCBI) at UC Berkeley and UCSF. BCBI website: bcbi.berkeley.edu Apply by Nov 1, 2026: berkeley.infoready4.com#freeformComp... (1/n)

bcbi.berkeley.edu

Bakar Computational Biomedicine Initiative | Bakar Computational Biomedicine Initiative

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Ian Sudbery @iansudbery.bsky.social · 12/09/2026

Holy moly, @ensembl.org killed biomart! Hope many R scripts are there out there that depend on biomaRt? How many people have informatics practicals, or undergraduate project instructions that depend on a web interface for bulk selection of data?

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Roger Highfield @rogerhighfield.bsky.social · 22/08/2026

More than 50 studies on cell ageing have apparently used the wrong antibody to identify a key protein in experiments, according to a science sleuth. www.nature.com/articles/d41...

nature.com

Sleuth identifies dozens of studies that used the wrong antibody

The case is the latest example of a scientific workhorse being misused in experiments.

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John Cocker @joecocker.bsky.social · 22/08/2026

For Lia 🪨

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Oxford Mathematics @oxfordmathematics.bsky.social · 16/08/2026

'Riffing with Roger', an Oxford Mathematics Unoriginal starring Roger Penrose. And another Roger (sort of).

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Lucy Siegle @lucysiegle.bsky.social · 16/08/2026

Hot hooves strikes again!

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Count Binface @countbinface.bsky.social · 16/08/2026

A brief note for Nadhim Zahawi.

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John Cocker @joecocker.bsky.social · 16/08/2026

On this day in 1942, a 5 year old Dutch Jewish girl arrived at Auschwitz with her mother and sister (12) where they were murdered in the gas chamber after selection. The father perished on the 30 Sep 1942. Her name was Betty Stodel Please support @auschwitzmemorial.bsky.social

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John Cocker @joecocker.bsky.social · 16/08/2026

On this day in 1942, a 7 month old Dutch Jewish girl arrived at Auschwitz with her mother where they were murdered in the gas chamber after selection. The father perished on the 30 Sep 1942. Her name was Edith Poppelsdorf Please support @auschwitzmemorial.bsky.social

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Count Binface @countbinface.bsky.social · 12/08/2026

For thousands of years, a solar eclipse has been a prophetic harbinger of a spectacular, epoch-making event. Just saying. #VoteBinface #Clacton

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Count Binface @countbinface.bsky.social · 07/08/2026

In Clacton right now. (Real, not AI!) #VoteBinface

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Oxford Clarion @oxfordclarion.bsky.social · 08/07/2026

Yes - he CAN! (Sorry, we had to).

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Headington News @headingtonnews.bsky.social · 04/07/2026

On 6 July 2026 Oxfordshire County Council will repair the lower part of the old stone wall in the alleyway alongside the Mason's Arms in Quarry, but the upper part of the stone wall will be replaced with a metal fence. See this Facebook post plus informative comment www.facebook.com/FriendsofQua...

facebook.com

Facebook

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Daphne Jackson Trust @daphnejacksontr.bsky.social · 02/07/2026

Yesterday we attended the launch of the Women in Research Charter with the Secretary of State for Science, Technology and Innovation, Liz Kendall - along with some of our Fellows. See the Trust being included in the Charter’s “Best Practice pack” - www.gov.uk/government/p...

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Netherlands Cancer Institute @nkinl.bsky.social · 01/07/2026

We are looking for a Junior Group Leader in Early Cancer Detection: an innovative scientist ready to build an independent research group and bring new ideas to one of our key research themes. Apply: www.nki.nl/news-events/... #tenure #vacancy #juniorPI #faculty #NKI

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Reposted by Benjamin Schuster-Böckler

Nitika Taneja @TanejaLab @nitikataneja.bsky.social · 01/07/2026

Very excited to share our new Nature study! We discovered that replication stress stabilizes CTCF-dependent chromatin loops enclosing stressed nascent DNA, where G9a-mediated heterochromatin protects it from nucleolytic degradation. rdcu.be/frzLg Huge thanks to all our collaborators and co-authors!

nature.com

Replication-stress-induced chromatin loops protect fork stability - Nature

Replication stress induces the formation of transient chromatin loops that enclose de novo heterochromatin-enriched stalled replication forks.

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Genetics Society UK @gensocuk.bsky.social · 26/06/2026

Congratulations to Prof Richard Durbin, winner of the 2026 Genetics Society Medal! His pioneering work in computational genomics has transformed how we analyse and understand genome sequences.

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UK 🇬🇧 🤝 🇺🇦 □ @ukbastard.bsky.social · 07/06/2026

Scientists ejected from diabetes conference for distributing journal reprints Those ousted included ADA journal editor-in-chief Steven Kahn and former ADA president Desmond Schatz arstechnica.com/science/2026...

arstechnica.com

Scientists ejected from diabetes conference for distributing journal reprints

Those ousted included ADA journal editor-in-chief Steven Kahn and former ADA president Desmond Schatz...

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Madhu Pai, MD, PhD @madhupai.bsky.social · 06/06/2026

We need to make sure this editorial goes viral Misguided Brushes of a Pen Continue to Dismantle and Destroy Biomedical Research in the United States: We Can No Longer Afford Complacency and Fear. We Must All Act Now! diabetesjournals.org/care/article...

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Dan Landau @landau.bsky.social · 04/06/2026

Exciting breakthrough technology from the lab, now live in @cellcellpress.bsky.social ! Instead of cutting the genome where proteins bind (e.g., Cut&Tag), D&D-seq scars the DNA with a deaminase, allowing single cell genome mapping of TFs and chromatin remodellers!

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Benjamin Schuster-Böckler @dagams.bsky.social · 31/05/2026

Is it just me, or did @anthropic.com crank up the sycophancy levels again in Opus 4.8? I'm getting a lot of "great idea" and "very good point" comments since moving from 4.7 🤔

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Benjamin Schuster-Böckler @dagams.bsky.social · 30/05/2026

This is really exciting - and more evidence for Rust taking over bioinformatics.

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Rob Klose @robklose.bsky.social · 29/05/2026

Help please! We need to do some large(ish) cell culture inhibiting E-cadherin with a monoclonal antibody. Does anyone have the DECMA-1 hybridoma cell line so we could purify our own antibody? or a similar monoclonal that would do the job. Any help greatly appreciated, just DM me. Please repost!

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Benjamin Schuster-Böckler @dagams.bsky.social · 29/05/2026

Cool new paper from Singapore's Gastric cancer consortium. They show that intestinal metaplasia in the stomach invariably features SBS17, just like Barrett's esophagus. They also confirm our findings from 2018 that SBS17 is strongly DNA-replication asymmetrical, but still no answer to what causes it

aacrjournals.org

Mutational Signatures and Clonal Hematopoiesis in Intestinal Metaplasia across Countries with Varying Stomach Cancer Incidence

International analysis of premalignant intestinal metaplasia identifies Helicobacter pylori variants, somatic drivers, mutational signatures, and clonal hematopoiesis as risk factors associated with p...

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Benjamin Schuster-Böckler @dagams.bsky.social · 22/05/2026

I know Sean from when I worked on PFAM, then met him again many times at HHMI's Janelia Farm campus. Seeing his group being destroyed like this is devastating - he's a titan of bioinformatics, his contributions have been transformational for genomics and proteomics. Utter madness!

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Robin Bisson @robinbisson.bsky.social · 22/05/2026

Patrick Vallance has twice written to MPs saying the budget for curiosity-driven research “will grow as the economy grows” But UKRI has flat cash for curiosity-led research through to 2030 When @isaacbarbosa1.bsky.social asked DSIT where the growth would come from, they had no answer A mystery

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Johan Duchêne @johanduchene.bsky.social · 21/05/2026

@sholtodavid.bsky.social Have you seen this WB from ThermoFisher? Still anti-p53 antibody, but another clone (MA-12648 instead MA5-12557). It also looks like that the band in lane 3 was rotated and reused in lane 4. Moreover, it seems that same band was used for the 2 different clones.

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Ian Sudbery @iansudbery.bsky.social · 13/05/2026

Incredible work. Will be going straight in my final year lectures as an example of how to combine genome-wide data with modelling to answer mechanistic hypotheses.

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Benjamin Schuster-Böckler @dagams.bsky.social · 09/05/2026

Extremely cool stuff coming from the team here: re-implementing htslib from scratch, with a focus on performance, compile-time checks and easier API #bioinformatics #ngs

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Reposted by Benjamin Schuster-Böckler

Seth Stadick @ducktapeprogrammer.bsky.social · 03/05/2026

For the most read-data heavy path in perbase, seqair is ~1.5x faster, which is awesome! I need to explore with some more datasets, but that's a pretty awesome win right off the bat.

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Oxford Clarion @oxfordclarion.bsky.social · 09/05/2026

Oxford City Council is to mark Europe Day today, by flying the European flag. Louise Upton, Lord Mayor of Oxford, fresh from her visit to twin town Leiden's Liberation Day celebration, (and re-election on Thursday), is hosting a European Reception in her Parlour at Oxford Town Hall.

Photo from last year's European reception. Around.a dozen people stand in front of an EU flag in a wood panelled room

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Isabel @isabelott.bsky.social · 07/05/2026

When viruses hijack our cells, they give our cells instructions on how to make their proteins. The current flu vax uses viruses grown in eggs, which make proteins a bit differently than we do. We usually need to defend against flu viruses that were made in human cells. mRNA vax=partial instructions!

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Benjamin Schuster-Böckler @dagams.bsky.social · 01/05/2026

Some cool news from the lab: Pascal just built a faster, more memory efficient htslib in pure Rust that passes the same test suite used for htslib itself! Give how fundamental htslib is to NGS applications, this could be hugely impactful. We'd love to get feedback and contributions! #rust #bioinf

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Joachim Frank @joachim123.bsky.social · 29/04/2026

I came here in 1975. I'm a Nobel Prize-winning scientist born in Germany during WWII, came here in 1975 thinking there was no way fascism could take hold in this country. I was wrong. I don't not want to be book-ended by two fascist regimes. We will stand up and set things right.

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Benjamin Schuster-Böckler @dagams.bsky.social · 21/04/2026

This is a really important issue - pubmed and other websites distort authorship contributions by only using the first/last author instead of honouring the "equal contributions" designation. This has real-life impact and disincentivises team science:

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Ludwig Cancer Research @ludwigcancer.bsky.social · 20/04/2026

Ludwig @oxfordcancer.bsky.social’s Sabrina James presented her research at #AACR2026 in a poster titled “Unexpected identification of tumor-infiltrating H. pylori or human papillomavirus (HPV) 16 in three exceptional responders in immunochemotherapy-treated esophageal cancer.” #CanSky #OncoSky

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Stephen Curry @scurry.bsky.social · 14/04/2026

Good piece. “If your problem with open access is that commercial publishers are hoovering up all the money, design open access interventions that specifically prevent commercial publishers from receiving your money.”

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Oxford Clarion @oxfordclarion.bsky.social · 12/04/2026

The Oxford Tube express coach is reinstating its White City stop, dropped in March’s timetable change in favour of a new Acton stop for the Elizabeth Line, after passenger feedback. White City will be a request stop, requiring passengers to ring the bell to alight. www.oxfordtube.com/service-upda...

oxfordtube.com

Service Updates | Oxford Tube - London to Oxford

Check real-time service updates, disruptions, timetable changes, fares and stop information. Stay informed before you travel.

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Tobias Warnecke @tobiaswarnecke.bsky.social · 08/04/2026

I wrote an essay. It’s about gain-of-function mutations. And penguins. Also ion channels, chihuahuas, the film Alien, recycled cardboard, and the Apollonian mind. Oh, and muffins. Thanks to the editors of #GENETICS @genetics-gsa.bsky.social for letting me take some stylistic liberties. 1/2

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Posit @posit.co · 08/04/2026

We are thrilled to announce that Positron Server is now available for academic use via JupyterHub! This gives students a robust #RStats & #Python data science IDE without needing a local install or new infrastructure. Learn more: positron.posit.co/blog/posts/2...

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