Anthropic is an AI safety and research company that's working to build reliable, interpretable, and steerable AI systems.

Maslennikova et al. identify the ER membrane protein CLCC1 as an interaction partner of the dystonia-linked AAA+ ATPase Torsin1A. Torsin1A sustains the function of CLCC1, which is proposed to facilitate fusion of the nuclear envelope during NPC biogenesis by forming an oligomer that promotes lipid bilayer approach and remodeling.

Nature Communications, Published online: 28 March 2026; doi:10.1038/s41467-026-70887-1Organelle biogenesis in the rapidly growing malaria parasite requires extensive membrane genesis and remodeling. Here a mechanism to directly supply lipids from the ER to the inner membrane complex (IMC), a de novo formed organelle needed for progeny formation, is shown.

Senior Research Scientist at Flatiron Institute. Research in computational biology and biophysics.

Nature Structural & Molecular Biology - Rocha-Roa et al. identify TMEM170 proteins as endoplasmic reticulum lipid scramblases that partner with bridge-like lipid transfer proteins BLTP1/Csf1...

Elhan et al. show that ATG2A acts with DGAT2, the enzyme producing triacylglycerol (TAG), in lipid droplet growth. By delivering diacylglycerol to lipid droplets, ATG2A not only fuels TAG production b...