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jennifersapia.bsky.social

@jennifersapia.bsky.social
34 followers 66 following 3 posts

Computational Chemist at InVirtuoLabs| PhD in Computational Biophysics/Biochemistry at @unifr.bsky.social

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Vanni Lab at UNIFR, Switzerland @labvanni.bsky.social · 24/06/2026
Check this mind-blowing story! How can a transmembrane protein adapt to a hugely diverse membrane topology to perform his job? Truly amazing in situ and integrative structural biology, and a great collaborative work by @veijosalo.bsky.social @yoelklug.bsky.social and @jennifersapia.bsky.social!
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Reposted by @jennifersapia.bsky.social
Veijo Salo @veijosalo.bsky.social · 07/04/2026
Excited to see this work led by @jennifersapia.bsky.social online! Substrate-dependent oligomerization modulates DGAT1 activity and subcellular localization www.biorxiv.org/content/10.6...
biorxiv.org
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Reposted by @jennifersapia.bsky.social
bioRxiv Biochemistry @biorxiv-biochem.bsky.social · 11/02/2026
Lipid Droplet Targeting Drives Substrate Access during Very Long Chain Fatty Acid Activation by Fat1 www.biorxiv.org/content/10.64898/20…
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Reposted by @jennifersapia.bsky.social
Vanni Lab at UNIFR, Switzerland @labvanni.bsky.social · 23/07/2025
Happy to share the latest work from the lab, led by @mudgal17.bsky.social‬, in collaboration with the Weis lab @ethzurich.bsky.social. How do nuclear membranes fuse during NPC assembly? We answer this question in our latest work, where we identify a new mechanism for membrane fusion… (1/13)
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jennifersapia.bsky.social @jennifersapia.bsky.social · 01/07/2025
Hey there!✨I’m thrilled to share that our latest research, in collaboration with the Tontonoz Lab (UCLA), has just been published in Nature Metabolism. Our study explores the fascinating role of polyunsaturated fatty acids in fat storage. Check it out! @labvanni.bsky.social @natmetabolism.nature.com
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jennifersapia.bsky.social @jennifersapia.bsky.social · 10/06/2025
Happy to share some glimpses of my recent PhD dissertation defense✨🎓📜 @unifr.bsky.social @unifrbiology.bsky.social #computationalbiophysics #moleculardynamics #biochemistry
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jennifersapia.bsky.social @jennifersapia.bsky.social · 15/04/2025
We are hiring!🎇💣 if you are looking for a position as PhD student or Postdoctoral researcher in the field of computational biophysics, apply via email! lnkd.in/ex7CseJP
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Reposted by @jennifersapia.bsky.social
Vanni Lab at UNIFR, Switzerland @labvanni.bsky.social · 19/03/2025
Jennifer also contributed to this amazing tour-de-force on the characterization of LPCAT3 and the role of polyunsaturated lipids in white adipose tissue. Congratulations to first authors Marcus Tol and Yuta Shimanaka from the Tontonoz lab! (3/3) www.biorxiv.org/content/10.1...
biorxiv.org
Dietary control of peripheral adipose storage capacity through membrane lipid remodelling
Complex genetic and dietary cues contribute to the development of obesity, but how these are integrated on a molecular level is incompletely understood. Here, we show that PPARγ supports hypertrophic ...
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Reposted by @jennifersapia.bsky.social
Vanni Lab at UNIFR, Switzerland @labvanni.bsky.social · 19/03/2025
The work of “soon-to-be” (we will miss her!) graduate Jennifer Sapia on the S-acylase ABHD17 (in collaboration with the lab of @lizconibear.bsky.social and grad student Sydney Holme) is also out! (1/3) buff.ly/4b3E0xy
buff.ly
An S-acylated N-terminus and a conserved loop regulate the activity of the ABHD17 deacylase
ABHD17 enzymes remove fatty acids from membrane proteins like NRas. This study shows that their activity depends on two mobile regions: an S-acylated N-ter
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