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Sam Collie

@collieman13.bsky.social
141 followers 213 following 22 posts

PhD student at the University of Michigan He/Him || Studying Cell Signaling in Neutrophils || I like Tea, Climbing, and Science

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Sam Collie @collieman13.bsky.social · 16/12/2025
Neutrophils promote the preservation of fat storage by adipocytes during cold-induced lipolysis www.nature.com/articles/s41... A new context that show the importance of Neutrophils and LTB4!!
nature.com
Neutrophils preserve energy storage in sympathetically activated adipocytes - Nature
Neutrophil-derived IL-1β has a role in preserving lipid stores during metabolic stress.
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Sam Collie @collieman13.bsky.social · 16/12/2025
these are amazing! it’s so scary to be in the situation with a loved one and not have a clear idea of whether it’s worth it to epi-pen since my understanding before this was that always meant 6 hours in the ER. Clear guidance is a god send here and will have me pushing for epi administration more.
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Sam Collie @collieman13.bsky.social · 09/12/2025
So happy to be making my return to @ascbiology.bsky.social CellBio after attending as an undergrad in 2019. It’s been an amazing conference and I’ve loved learning about all the different nuclear biology research being done!
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H. B. Beryl Rappaport @hbrappap.bsky.social · 25/11/2025
So happy to announce our new preprint, “A geothermal amoeba sets a new upper temperature limit for eukaryotes.” We cultured a novel amoeba from Lassen Volcanic NP (CA, USA) that divides at 63°C (145°F) 🔥 - a new record for euk growth! #protistsonsky 🧵
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Michael Baym @baym.lol · 20/11/2025
Hot off the press! Our latest paper led by @fernpizza.bsky.social, understanding how plasmids evolve inside cells. These small, self-replicating DNA circles live inside bacteria and carry antibiotic resistance genes, but also compete with one another to replicate. 1/ www.science.org/doi/10.1126/...
science.org
Intracellular competition shapes plasmid population dynamics
From populations of multicellular organisms to selfish genetic elements, conflicts between levels of biological organization are central to evolution. Plasmids are extrachromosomal, self-replicating g...
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Prakash Lab at Stanford @prakashlab.bsky.social · 01/11/2025
Success. Nearly 259 Foldscope deployed in hands of unsuspecting candy crazy kids. Halloween is always more colorful with the microscopes - specially in a few weeks they could look at the micro-fauna of the teeth with so much sugar consumption.
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Omaya Dudin 𓂆 ¦🍉¦🦠¦🔬¦ @dudinlab.bsky.social · 31/10/2025
🚨Our collaboration with @centriolelab.bsky.social & @gautamdey.bsky.social is out today in @cp-cell.bsky.social We show that #Expansion #Microscopy is a broad-spectrum modality for Euks, enabling 3D phenotypic maps rooted to phylogeny. #ProtistsOnSky #SciComm #SciSky www.cell.com/cell/fulltex...
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Sam Collie @collieman13.bsky.social · 09/10/2025
Great example of incredibly useful and relevant “negative” data
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Dr. Cate Peña @cate-cholamine.bsky.social · 09/10/2025
I freaking love that this team must have been like TIME TO PREPRINT Prenatal Acetaminophen Exposure Does Not Disrupt Human Fetal Brain Development in Cortical Organoid Models www.biorxiv.org/content/10.1...
biorxiv.org
Prenatal Acetaminophen Exposure Does Not Disrupt Human Fetal Brain Development in Cortical Organoid Models
Acetaminophen (APAP) is the most widely used analgesic during pregnancy, yet epidemiological studies have reported conflicting associations between prenatal exposure and neurodevelopmental disorders (...
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Sam Collie @collieman13.bsky.social · 09/09/2025
This article by @pracheeac.bsky.social and @mbeisen.bsky.social sums up (in much stronger language) a lot of what I heard in a recent talk by Gary Ward (U of Vmt). thescientistpapers.substack.com/p/how-to-be-...
thescientistpapers.substack.com
How to be a scientist in a post-journal world
When we created this site to write about things in science that need to be fixed, we chose not to start with publishing, even though it has been our preoccupation for decades.
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Sam Collie @collieman13.bsky.social · 04/09/2025
Really compelling argument to get rid of p-values in cell biology in favor of confidence intervals. Everytime I think about the state of statistics in biological research it makes me want to run, hide and become a statistician. rupress.org/jcb/article/...
rupress.org
Journal of Cell Biology | Rockefeller University Press
Journal of Cell Biology (JCB) publishes advances in any area of basic cell biology as well as applied cellular advances in fields such as immunology, neurobiology, metabolism, microbiology, developmen...
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Better Things Are Possible @internethippo.bsky.social · 20/08/2025
I'm not right wing but some of this "woke" stuff is a little over the top [6 months later] Slavery was fine. Your city is under martial law
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NY Times Pitchbot @nytpitchbot.bsky.social · 23/07/2025
Opinion | Don't get angry at ICE agents. They are just following orders. by Adolf Eichmann
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Sam Collie @collieman13.bsky.social · 22/07/2025
Cool new method for generating CAR-Macrophages In Vivo utilizing their phagocytosis of exogenous ennucleated stem cells! www.pnas.org/doi/10.1073/...
pnas.org
In vivo generation of CAR macrophages via the enucleated mesenchymal stem cell delivery system for glioblastoma therapy | PNAS
Glioblastoma multiforme (GBM) is one of the most aggressive intracranial tumors for which there is no effective treatment. Chimeric antigen recepto...
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Carl T. Bergstrom @carlbergstrom.com · 08/06/2025
"Through AI Fluency, Ohio State students will be ‘bilingual’ — fluent in both their major field of study and the application of AI in that area" Ohio State really not beating the allegations out of Ann Arbor here.
nbc4i.com
Ohio State announces every student will use AI in class
COLUMBUS, Ohio (WCMH) — Starting this fall, every Ohio State student will be asked to use artificial intelligence. “Through AI Fluency, Ohio State students will be ‘bilingual’ — fluent …
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Carole Parent Lab @caroleparentlab.bsky.social · 23/05/2025
Excited to share our recently published study on how DNA secretion in neutrophils modulates their inflammatory response spearheaded by @sbarya.bsky.social Thanks to all our collaborators and contributors for their help getting this story to press. 👏👏 www.nature.com/articles/s41...
nature.com
Neutrophils secrete exosome-associated DNA to resolve sterile acute inflammation - Nature Cell Biology
Arya et al. report that migrating neutrophils resolve acute inflammation by releasing exosomes associated with nuclear DNA. This process is distinct from the release of neutrophil extracellular traps,...
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Ebrahim Lab @ebrahim-lab.bsky.social · 17/05/2025
Early for #MicroscopyMonday: #Hemifusomes- Newly discovered ESCRT-independent intermediates of intraluminal vesicle and multivesicular body formation! In collaboration with the Kachar Lab at the NIH and out today in @natcomms.nature.com : rdcu.be/emtQu #cryoET #trafficking #organelle #hemifusion
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Carl T. Bergstrom @carlbergstrom.com · 04/04/2025
Pretty much everything is fucked, but here is some beautiful and exciting science from @archaeon-alex.bsky.social and colleagues. www.science.org/doi/10.1126/...
science.org
Tissue-like multicellular development triggered by mechanical compression in archaea
The advent of clonal multicellularity is a critical evolutionary milestone, seen often in eukaryotes, rarely in bacteria, and only once in archaea. We show that uniaxial compression induces clonal mul...
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Chelsey Spriggs @drsprggs.bsky.social · 02/04/2025
Many brilliant scientists are now being punished by having our funding terminated because we are from underrepresented groups. We did everything right and we EARNED these awards. Remember us when you’re making decisions on whether DEI should be sacrificed to “protect” research funding. #InMyFeelings
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Sam Collie @collieman13.bsky.social · 28/03/2025
Incredible findings regarding the mechanism of active transport through Nuclear Pore Complexes. Seems importin travels only through the periphery of the central channel leaving a large dead zone in the center. www.nature.com/articles/s41...
nature.com
Overlapping nuclear import and export paths unveiled by two-colour MINFLUX - Nature
High spatiotemporal precision tracking using 3D MINFLUX shows that nuclear import and export occur in overlapping regions of the central pore, providing insight into transport across the nuclear pore ...
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Alex Webb Lab @alexwebblab.bsky.social · 28/11/2024
www.nature.com/articles/s41... I am amazed at this achievement. This is done using fairly off the shelf components. 🧪
nature.com
Ångström-resolution fluorescence microscopy - Nature
The authors introduce a single-molecule DNA-barcoding method, resolution enhancement by sequential imaging, that improves the resolution of fluorescence microscopy down to the Ångström scale using off...
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Developing Future Biologists @dfb-um.bsky.social · 19/03/2025
Thank you so much to our donors so far! You’re helping to make DFB possible. There’s still time to donate! You can use the link in our bio to access the official DFB Giving Blueday page. #givingblueday
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Developing Future Biologists @dfb-um.bsky.social · 19/03/2025
Happy Giving Blueday! We appreciate all you do to help us continue our missing and make developmental biology accessible to students across the country #givingblueday You can support us at maizeraise.umich.edu/schools/Univ...
maizeraise.umich.edu
Developing Future Biologists
Join me and make a gift to Giving Blueday 2025
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Developing Future Biologists @dfb-um.bsky.social · 19/03/2025
Hear from current and previous instructors, some of our alumni and one of our faculty advisors about the importance of the work we are doing! Donate now to help support our mission.
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Sam Collie @collieman13.bsky.social · 13/01/2025
Fascinating science inspires incredible art. Check out the video, it’s one of the least clickbait things i’ve seen
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JP @jpbrammer.bsky.social · 13/01/2025
Black Swan is my comfort movie
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Sam Collie @collieman13.bsky.social · 12/01/2025
I had an amazing time at the Directed Cell Migration Gordon Research Seminar. Excited for the next phase of amazing science and community in beautiful Tuscany!!
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Better Things Are Possible @internethippo.bsky.social · 12/01/2025
The scientific method served humanity well for hundreds of years but it was rendered obsolete in 2013 with the discovery of Vibes
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Tim @timisstuck.bsky.social · 11/01/2025
Hello Florence! From here to the Gordon conference on Directed Cell Migration, can’t wait!
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Sam Collie @collieman13.bsky.social · 30/12/2024
Game of the year: Balatro Album of the year: Peter Cat Recording Co. - BETA Movie of the year: The Holdovers Book of the year: The Way of Kings - Brandon Sanderson (i read it this year)
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Sam Collie @collieman13.bsky.social · 23/11/2024
everyone should go see John Proctor is a Villain
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Sam Collie @collieman13.bsky.social · 21/11/2024
not to be totally ancient, but scrolling on here has me thinking back to a simpler time of old school twitter where getting mad on the internet was still fun and fresh to me
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