iiinova — where your digital self keeps evolving

Prachee Avasthi @pracheeac.bsky.social · 21/08/2026

Here’s a hugely important vacancy at the NIH at a critical moment of technological and scientific change. The NIH is looking for a deputy director of intramural research. 1/

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Arjun Krishnan @compbiologist.bsky.social · 13/04/2026

What is the PhD actually for, especially now that AI can do increasingly more of what we train scientists to do? compbiologist.substack.com/p/what-is-th... A response to @pracheeac.bsky.social's thought-provoking essay "Free the PhD".

compbiologist.substack.com

What is the PhD actually for?

A response to Prachee’s “Free the PhD”, and a critique of my own work

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Prachee Avasthi @pracheeac.bsky.social · 13/01/2026

New job alert! If you're passionate about open science, organized, enthusiastic about meeting new people doing exciting work in this space, and want to nerd out with me on all the ways we can move the needle on open science @asterainstitute.bsky.social, apply now! jobs.ashbyhq.com/astera/f085e...

jobs.ashbyhq.com

Open Science Operations Associate

Join Astera as an Open Science Operations Associate! Support open science programs, connect with researchers, and help accelerate scientific progress. In-person, based in Emeryville, CA.

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Michael Hoffman @michaelhoffman.bsky.social · 12/01/2026

The "my competitor will see my preprint and replicate/rush their story to a journal" = their competitor has to have already done at least the rate-limiting parts of the work. To me, this is about someone wanting to receive exclusive credit for work that other groups were doing simultaneously.

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Michael Hoffman @michaelhoffman.bsky.social · 10/01/2026

What genetic change to Indian wheat led to superior baking in a tandoor? A naan sense mutation

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Prachee Avasthi @pracheeac.bsky.social · 07/11/2025

After working closely together across two open science orgs over the last 7+ years, I’ll really miss working with @jessicapolka.bsky.social. She’s a total pro, an exceptional operator, a sharp strategist, and just a fantastic human ❤️. Really excited to see all she does next!

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Prachee Avasthi @pracheeac.bsky.social · 04/11/2025

Spoke recently to the great folks at the science foundation on their efforts to fund curiosity-driven science. They have a new RFA out for catalytic awards (up to $10K). Take a look if you’re itching to expand or try out a new idea. science-foundation.org

science-foundation.org

Public Science, Public Good – Public Science, Public Good

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Prachee Avasthi @pracheeac.bsky.social · 22/10/2025

ICYMI: the deadline to nominate a publishing trailblazer so we can amplify their efforts is October 31!

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SPARC @sparcopen.bsky.social · 21/10/2025

ICYMI: Read our impact story on policies at HHMI, Gates & Astera promoting #OpenAccess #OpenScience #OpenData. Thought leaders helping accelerate discovery in science @madubs.bsky.social @openaccessmaven.bsky.social @pracheeac.bsky.social! sparcopen.org/impact-story...

sparcopen.org

Funders Roll Out Next Gen Open Policies - SPARC

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Prachee Avasthi @pracheeac.bsky.social · 16/10/2025

We have a bunch of new job ads out @arcadiascience.com. If you haven’t checked them out, take a look! www.arcadiascience.com/careers

arcadiascience.com

Careers | Arcadia Science

Evolve with Arcadia.

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Prachee Avasthi @pracheeac.bsky.social · 16/10/2025

We have a bunch of new job ads out @arcadiascience.com. If you haven’t checked them out, take a look! www.arcadiascience.com/careers

arcadiascience.com

Careers | Arcadia Science

Evolve with Arcadia.

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Ronen Tamari @ronentk.me · 15/10/2025

1/ 📢 New blog post! @pracheeac.bsky.social recently wrote a great piece about the need for paradigm shifts in science communication: “Stop building faster horses when we need fundamentally different vehicles.” 🧵https://bsky.app/profile/pracheeac.bsky.social/post/3m2exwtn6o22i

bsky.app

Prachee Avasthi (@pracheeac.bsky.social)

New Blog Post: Scholarly Communication Is a Research Problem. This Means You. https://pracheeac.substack.com/p/scholarly-communication-is-a-research

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Prachee Avasthi @pracheeac.bsky.social · 15/10/2025

🚨New job alert! We’re trying to put some tailwind behind developing out some of our new molecular, organismal, and high dimensional phenotyping capabilities @arcadiascience.com and are launching an effort to fuel the fire. But first I need a project director to oversee it.

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Prachee Avasthi @pracheeac.bsky.social · 10/10/2025

Waiting for incentives to change in scientific publishing? We’ve got you! I hope other funders follow suit to make the most of their research dollars

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Prachee Avasthi @pracheeac.bsky.social · 08/10/2025

Some scientists aren’t waiting for journals to catch up. They’re showing us what’s next. The Beyond the Journal awards honor those breaking the mold in how science is shared. More details: pracheeac.substack.com/p/off-roadin... Nominate or self-nominate here: www.experiment.foundation/beyond

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Prachee Avasthi @pracheeac.bsky.social · 08/10/2025

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Prachee Avasthi @pracheeac.bsky.social · 04/10/2025

New Blog Post: Scholarly Communication Is a Research Problem. This Means You. pracheeac.substack.com/p/scholarly-...

pracheeac.substack.com

Scholarly Communication Is a Research Problem. This Means You.

Scholarly Communication Is a Research Problem.

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Prachee Avasthi @pracheeac.bsky.social · 29/09/2025

A serious and useful thread with permission to take AGI seriously by @jascha.sohldickstein.com over at X x.com/jaschasd/sta...

x.com

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Prachee Avasthi @pracheeac.bsky.social · 28/09/2025

Ordered a shirt that reminds me unambiguously of @richardsever.bsky.social 😂

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Prachee Avasthi @pracheeac.bsky.social · 26/09/2025

So @mbeisen.bsky.social and I wrote this not just to sway HHMI to stop walking the tightrope to make all parties comfortable and be clear about their trajectory but because it’s in all scientist’s hands to decide what they want to do open.substack.com/pub/thescien...

open.substack.com

Open letter to HHMI on their Immediate Access to Research Policy

The following is in response to a letter sent to the HHMI community on September 24, 2025 and refers to HHMI’s new Immediate Access to Research Policy. The original letter appears at the bottom below ...

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Prachee Avasthi @pracheeac.bsky.social · 15/09/2025

Right now is the best chance the scientific community has ever had to end the artificial scarcity of academic journals. 1/

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Prachee Avasthi @pracheeac.bsky.social · 15/09/2025

Right now is the best chance the scientific community has ever had to end the artificial scarcity of academic journals. 1/

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Prachee Avasthi @pracheeac.bsky.social · 08/09/2025

While journal publishing has always been deeply problematic, hurting both the pace and trajectory of science, something is happening in this moment that is finally causing the system to crumble under its own weight and cost. 1/

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James Fraser @fraserlab.com · 08/09/2025

Why hasn't Preprint Peer Review caught on more? I discovered a small, but simple reason - authors are missing out on the JOY of getting feedback because they aren't notified when feedback occurs. more in thread below!

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Stephanie Wankowicz @stephanieaw.bsky.social · 31/08/2025

TTPD #6 with @fraserlab.com. We chatted about the recent meetings, latest news, open science, social media, and, of course, the recent engagement. podcasts.apple.com/us/podcast/e... wankowiczlab.com/2025/08/31/T...

podcasts.apple.com

Episode 6: Open Science and the Future of Engagement

Podcast Episode · The Tortured Proteins Department · 08/31/2025 · 54m

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Prachee Avasthi @pracheeac.bsky.social · 31/08/2025

Just declined to participate in the “biotech, pharma, & curiosity-driven labs” panel at @ascbiology.bsky.social this year because I am not sure I’ll attend (the 1st ASCB meeting I’ll have skipped in 15 years). That said, we’re actively recruiting @arcadiascience.com from this community/skillset…

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openRxiv @openrxiv.bsky.social · 18/08/2025

We’re excited to share @tracykteal.bsky.social will be the new CEO of openRxiv. 🎉 A scientist & nonprofit leader, she has served as Interim COO since launch. Her appointment signals continuity in leadership & our commitment to independence, transparency & open science. openrxiv.org/announcing-c...

openrxiv.org

Dr. Tracy Teal named CEO of openRxiv, to lead the next phase in the evolution of open science - openRxiv

After an exhaustive, international search, the openRxiv Board of Directors has appointed Dr. Tracy Teal as the organization’s inaugural CEO. Dr Teal has served as interim COO of openRxiv since its lau...

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Prachee Avasthi @pracheeac.bsky.social · 15/08/2025

Was fantastic to have @ronent.bsky.social @cosmik.network as an open science fellow at @asterainstitute.bsky.social! Excited to see how they’ll progress!

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Prachee Avasthi @pracheeac.bsky.social · 14/08/2025

Thrilled we're getting tons of interest from the community looking to follow along and participate! We'll be working on a concerted effort to keep in touch with folks – but for now, if you're interested, please get in touch via the google form in the post below so we can learn a bit more about you!

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Prachee Avasthi @pracheeac.bsky.social · 13/08/2025

Open science can sometimes been seen as a risk but IME there are definitely people out there doing research more openly to advance science despite that. 1/4

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Prachee Avasthi @pracheeac.bsky.social · 12/08/2025

Happy @diffuseproject.bsky.social launch day! Check out our latest effort. We're grappling with how to better understand protein dynamics and capture/share the information that would best allow the community to make use of that data. Take a look!

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Prachee Avasthi @pracheeac.bsky.social · 09/08/2025

Encourage following @ryan-york.bsky.social who is new to this site & our Head of Platform at Arcadia. When we say we aim to leverage the structure of biology (evolution) to inform hypotheses & test them efficiently, what does that mean? Ryan runs the part of the org that develops those solutions

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Prachee Avasthi @pracheeac.bsky.social · 08/08/2025

We’re growing @arcadiascience.com & are on the lookout for talent to run new pilot projects contributing to our broader goals. Seeking computational + wet lab fluency to iterate independently on new projects. If you’re a creative scientist w/ ambitious ideas, apply! jobs.lever.co/arcadiascien...

jobs.lever.co

Arcadia Science - Project Scientist

A Bit About Us: We are Arcadia Science, an evolutionary biology company founded and led by scientists. Our mission is to turn natural innovations into real-world solutions by developing systematic, an...

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Prachee Avasthi @pracheeac.bsky.social · 12/02/2025

Basic science in the private sector for the benefit of human health? We hope this is just the beginning! Check out our latest effort @arcadiascience.com to help match genes of interest with research organisms using Zoogle! zoogle.arcadiascience.com Blog post: arcadiascience.com/blog/zoogle

zoogle.arcadiascience.com

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Sri Kosuri @srikosuri.bsky.social · 08/02/2025

It’s been a tough few weeks. My 10yo daughter was diagnosed with a very rare, aggressive cancer called interdigitating dendritic cell sarcoma (IDCS). I’m reaching out to identify clinicians/patients who have encountered pediatric IDCS or other (non-LCH) dendritic or histiocytic sarcomas cases.

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Ubadah Sabbagh @ubadahsabbagh.com · 07/02/2025

New job @arcadiascience.com! Ideally you've got a few years of experience post-PhD, in academia or elsewhere, and have some computational fluency in addition to experimental expertise. Added bonus, you'd get to join our pastry-fueled preprint comment parties like the one we're having today :)

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Prachee Avasthi @pracheeac.bsky.social · 07/02/2025

🚨Job Alert @arcadiascience.com! Are you an independent, generative, rigorous scientist that can pivot quickly? Can you apply your unique skills to a wide range of bio & tech problems? Can you work with other stellar scientists skilled in orthogonal domains? Join us! jobs.lever.co/arcadiascien...

jobs.lever.co

Arcadia Science - Project Scientist

A Bit About Us: We are Arcadia Science. Arcadia is a science company founded and led by scientists. Our mission is to transform evolutionary innovations into real-world solutions by openly developing ...

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Prachee Avasthi @pracheeac.bsky.social · 27/01/2025

IMO this is a particularly bad time to sequester oneself from information voluntarily

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Prachee Avasthi @pracheeac.bsky.social · 25/01/2025

Mad at you @mikefeigin.bsky.social for making me come here to tell you I’m stoked for our annual matchup

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Richard Sever @richardsever.bsky.social · 24/01/2025

The "bioRxiv should check methods" issue came up frequently on twitter. See thread in which @pracheeac.bsky.social @michaelhoffman.bsky.social and I explain the complexity x.com/cshperspecti... which I'll summarizeagain _here_ for those who don't want to go _there_ 1/n

x.com

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