ALT: Man Lying on a Pile of Money

Grinat et al. identify IRS2 as a central regulator of placental syncytiotrophoblast differentiation. Using mouse genetics, CRISPR-engineered trophoblast stem cells, and human trophoblast stem cells an...

Parents want accountability after study went disastrously wrong, Science and Retraction Watch investigation reveals

During regeneration, tissues must translate transient cellular variability into stable spatial organization. Tissue architecture generates a density-dependent window of heterogeneity in the mechanosen...

During regeneration, tissues must translate transient cellular variability into stable spatial organization. Tissue architecture generates a density-dependent window of heterogeneity in the mechanosen...

The recent launch of qed’s “top 1%” preprint ranking has sparked controversy, with concerns about its arbitrary nature, potential harm to authors, and low-quality inclusions. Whil…

Welcome to preLights, the preprint highlights service run by the biological community and supported by The Company of Biologists. Here, a team of scientists regularly review, highlight and comment on ...

Summary: This Editorial offers an honest look at impact factor trends in developmental biology, explains how Development serves its community, and makes the case that sustaining developmental biology ...

The rapid accumulation of single-cell RNA-Seq (scRNA-seq) data across multiple repositories presents major challenges for data accessibility, integration, and reproducibility. While primary…

Summary: Interferon-Φ1 signaling is required for early neutrophil recruitment after zebrafish heart injury, revealing a key immune trigger that shapes inflammation and may influence efficient cardiac ...

Islets of Langerhans are highly structured mini-organs containing hormone-producing cells of the pancreas that regulate glucose metabolism. Studies of…

The ERC Scientific Council has listened to the concerns from members of the research community about the recent announcement on changes to the re-submission rules. The changes, intended to manage the ...

All animal embryos begin as totipotent zygotes that cleave and produce cells with restricted fate potentials. However, the timing of when totipotency is lost and the processes through which embryonic cells acquire fates vary across species. Embryos with invariant cleavage programs, e.g., of nematode …

This Review discusses the genetics of obesity, highlighting its diverse forms and describing technological advancements in genetic studies that may enable precision medicine strategies to combat obesi...

When a prestigious journal scrapped accept-reject decisions on submitted papers, some scientists rebelled, and the editor-in-chief was fired.