iiinova — where your digital self keeps evolving

Reposted by Cihan Erkut

Deutsches Krebsforschungszentrum (DKFZ) @dkfz.bsky.social · 17/09/2026

Dreaming of a career in cancer research? Join the International PhD Program at @DKFZ — Germany’s largest biomedical research center. Explore #cancerresearch including #cancerbiology, #bioinformatics, #epidemiology & #medicalphysics. The Winter Selection is open now 👉 apply t1p.de/hl56b

055

Reposted by Cihan Erkut

Nils Homer @nilshomer.com · 28/06/2026

🚀 new bwa-mem3 is out. Why use it? - 🏛️keep using a bwa-mem variant (avoid revalidation/reprocessing) - 🚅 1.7x faster/20% less memory than bwa-mem2 - 🧬native methylation support (asymmetric scoring) - ✅ matches bwa-mem2 output - 👊opt-in knobs to go even 2x faster bwa-mem3.readthedocs.io/en/latest/

bwa-mem3.readthedocs.io

Home - bwa-mem3

Accelerated short-read alignment, derived from bwa-mem2

14219

Reposted by Cihan Erkut

Physics of Life Dresden @poldresden.bsky.social · 24/06/2026

🏆 Introducing the inaugural Suzanne Eaton Awards for Physics of Life! We're thrilled to announce the 2026 recipients: L. Mahadevan @harvard.edu and Anna Erzberger @embl.org. 👨‍🔬Both scientists will give award lectures on 20. November, more info to follow ➡️Read our announcement here: tud.link/cjm8t2

25816

Reposted by Cihan Erkut

Daniel Lipka @dblipka.bsky.social · 29/05/2026

🧵 NEW PAPER in @bloodjournal.bsky.social! Why do IDH1 mutations almost exclusively drive myeloid #leukemia, while IDH2 mutations occur in both myeloid AND lymphoid cancers? 🤔 #AML #Epigenetics Despite sharing the same biochemical mechanism, they are NOT equivalent. Here's what we found 👇

2329

Reposted by Cihan Erkut

EACR - European Association for Cancer Research @helloeacr.bsky.social · 13/05/2026

We’ve welcomed participants from 33 countries at the EACR's Cancer Genomics, Multiomics and Computational Biology conference in Essen this week! 🤩 This afternoon's poster session has sparked many interesting conversations between researchers.

073

Reposted by Cihan Erkut

Matthia Karreman @matthiakarreman.bsky.social · 13/05/2026

What if brain metastatic cells do not act alone, but form #networks to help them grow? In our new #preprint, we show that #brainmetastases form malignant, gap-junction mediated #networks that drive cell cycle progression & neural features through Ca²⁺ signaling. www.biorxiv.org/content/10.6... 🧵👇

2259

Reposted by Cihan Erkut

NCT Heidelberg @nct-heidelberg.bsky.social · 10/04/2026

🧬 Der desmoplastische klein- und rundzellige Tumor ist selten, aggressiv und schwer zu behandeln. Forschende am NCT Heidelberg und am @dkfz.bsky.social haben 30 Tumoren umfassend analysiert und für fast alle Betroffenen potenzielle personalisierte Therapieoptionen abgeleitet. (1/2)

144

Reposted by Cihan Erkut

Deutsches Krebsforschungszentrum (DKFZ) @dkfz.bsky.social · 27/03/2026

Dreaming of a career in cancer research? Join the International PhD Program at DKFZ - Germany’s largest biomedical research center. Explore #cancerresearch including #cancerbiology, #bioinformatics, #epidemiology & #medicalphysics. The Summer Selection is open now 👉 apply here: t1p.de/hl56b

11111

Reposted by Cihan Erkut

Xuebing Wu @xuebingwu.bsky.social · 31/01/2026

Does the noncoding genome actually carry more genetic information than coding seqs? Motivated by this question we mutated every bp in the 10kb MYC locus. Results are even more exciting: Decoding the MYC locus reveals a druggable ultraconserved RNA element www.biorxiv.org/content/10.6...

biorxiv.org

412846

Reposted by Cihan Erkut

Hasindu Gamaarachchi @hasindu2008.bsky.social · 04/12/2025

Cornetto v0.2.0 is now released for using programmable selective nanopore sequencing for genome assembly. GitHub: github.com/hasindu2008/... Paper: nature.com/articles/s41... Datasets: hasindu2008.github.io/cornetto/doc... ... and a banner made by Ira Deveson referring to ‘no boring bits’.

1218

Reposted by Cihan Erkut

EMBL @embl.org · 27/11/2025

Anthony A. Hyman will become EMBL’s next Director General. He joins EMBL from @mpi-cbg.de in Dresden. He is also Professor of Molecular Biology @tudresden.bsky.social, and was a group leader at EMBL Heidelberg from 1993 to 1999. www.embl.org/news/people-...

1125368

Reposted by Cihan Erkut

Lars Velten @larsplus.bsky.social · 20/11/2025

We are looking for a postdoc to join our team! If you're interested in translating a cutting edge genomics technology (www.nature.com/articles/s41...) to real-life applications in hematology, this is for you. We offer a unique working environment ON THE BEACH: recruitment.crg.eu/content/jobs...

Yes, this is where you would work (the round building, not the boat)

01716

Reposted by Cihan Erkut

Deutsches Krebsforschungszentrum (DKFZ) @dkfz.bsky.social · 05/11/2025

🚀 Thinking about your next big career step in science? The Int'l PhD Program at DKFZ could be a perfect fit for you. 🌍 Work in an international environment, with 500+ doctoral researchers 🔬 Do cutting-edge cancer research Curious? Join our online info session on 20 Nov. Register here: t1p.de/ws7q3

0910

Reposted by Cihan Erkut

Max Planck Institute for the Science of Light (MPL) @mpi-scienceoflight.bsky.social · 08/10/2025

With deep sadness, we share that Prof. Jochen Guck, Director at the Max Planck Institute for the Science of Light passed away on October 3. His visionary work bridged physics and medicine. We have lost a brilliant scientist and dear friend. mpl.mpg.de/news/article... @fau.de 📸 Stephan Spangenberg

Professor Jochen Guck, Director at the Max Planck Institute for the Science of Light (MPL), He headed the division “Cell Physics” at MPL and the Max-Planck-Zentrum für Physik und Medizin (MPZPM).

58030

Cihan Erkut @cihanerkut.bsky.social · 04/09/2025

It has been an honor for me to have worked in this fantastic project with great scientists and brilliant students for the last few years.

021

Reposted by Cihan Erkut

Cancer Core Europe @cancercoreeurope.bsky.social · 18/08/2025

📢 Registration now open for HARPOON Conference, Nov 27–28 2025 in Heidelberg! Precision oncology, multi-omics, & translational research. indico.dkfz.de/event/1230/ @nct-heidelberg.bsky.social @dkfz.bsky.social @vhio.bsky.social @ki.se @crukcamcentre.bsky.social @nkinl.bsky.social @gustaveroussy.fr

1116

Reposted by Cihan Erkut

TanentzapfLab @tanentzapflab.bsky.social · 13/08/2025

The goal of a PhD is not to learn some facts or read a few papers or learn a bunch of techniques. The goal of a PhD is to learn independence, problem solving, how to finish things you start, resilience, & gain the ability to adapt & think creatively. Learning these things is hard.

433787

Reposted by Cihan Erkut

Robert Reich @rbreich.bsky.social · 08/07/2025

Your Prime Day reminder that half of Amazon warehouse workers struggle with food & housing costs. A third have had to rely on government assistance like SNAP — which is about to get cut. If Bezos can spend $50M on a wedding, Amazon can afford to treat its workers with dignity.

10053308510395

Cihan Erkut @cihanerkut.bsky.social · 19/06/2025

After so many inspiring talks and thought-provoking conversations, it's now time to go home. Many thanks to the organizers of #EACR2025 for this extraordinary event. Hope to meet everyone again next year in Budapest.

340

Cihan Erkut @cihanerkut.bsky.social · 18/06/2025

If you are at the #EACR2025 today and interested in integrative genomics of rare cancers, feel free to visit me by the poster P-006 in Pavilion 1 during the poster session.

1103

Cihan Erkut @cihanerkut.bsky.social · 17/06/2025

This was one of the most inspiring talks I've ever heard in my life! #eacr2025

041

Reposted by Cihan Erkut

Johanna Joyce @johannajoyce.bsky.social · 16/06/2025

Incredible opening keynote by Charlie Swanton - spanning tumour initiation, aging, environmental exposure and much more 👏👏 #EACR2025 @charlesswanton.bsky.social @crick.ac.uk @helloeacr.bsky.social

0405

Reposted by Cihan Erkut

ETEP Isolde @etep-isolde.bsky.social · 22/04/2025

„Kinder, die lernen, ihre eigenen Gefühle zu verstehen, können auch die Gefühle anderer besser wahrnehmen.“ Lisa Feldman Barrett #blueLZ

0134

Reposted by Cihan Erkut

Janelle Shane @janelleshane.com · 13/04/2025

1. LLM-generated code tries to run code from online software packages. Which is normal but 2. The packages don’t exist. Which would normally cause an error but 3. Nefarious people have made malware under the package names that LLMs make up most often. So 4. Now the LLM code points to malware.

12078743580

Reposted by Cihan Erkut

Wissenschaftsrat @wissenschaftsrat.de · 09/04/2025

The German Science and Humanities Council and the German Rectors' Conference criticise attacks on academic freedom and declares its solidarity with US institutions and scientists. An attack on science anywhere is an attack on science everywhere. #AcademicFreedom #HandsOff

28741

Reposted by Cihan Erkut

Stefan Fröhling @stefanfrohling.bsky.social · 19/03/2025

Are you interested in groundbreaking research in the field of personalized cancer therapies? If so, please join us at DKFZ for an exciting and inspiring afternoon and hear from key opinion leaders and rising stars about what is on the horizon.

282

Reposted by Cihan Erkut

NCT Heidelberg @nct-heidelberg.bsky.social · 19/03/2025

** Meyenburg-Preis an Michel Sadelain ** 🏆Verleihung im Rahmen des Cancer Research Award Symposiums der Meyenburg-Stiftung 📅 2. April 2025 am Deutschen Krebsforschungszentrum in Heidelberg Programm und Anmeldung unter www.nct-heidelberg.de/das-nct/news... @dkfz.bsky.social

032

Reposted by Cihan Erkut

micamer.bsky.social @micamer.bsky.social · 11/03/2025

We would love feedback on a new NCBI-BLAST service we are launching today: sky-blast.com Under the hood it's the same BLAST executable and databases provided by NCBI, with a replica of the NIH's interface - providing an alternative to the US gov service that's less congested, faster & more reliable

1012274

Reposted by Cihan Erkut

Richard Sever @richardsever.bsky.social · 11/03/2025

Big news: we are setting up a new non-profit organization to run bioRxiv and medRxiv. It's called openRxiv [no it's not a new preprint server; it's dedicated organization to oversee the servers] openrxiv.org 1/n

openrxiv.org

Homepage - openRxiv

openRxiv is an independent non-profit, the new organizational home for bioRxiv and medRxiv, enabling researchers to instantly share groundbreaking findings with the global scientific community.

552558846

Reposted by Cihan Erkut

The German Human Genome-Phenome Archive @ghga.bsky.social · 26/02/2025

New release headed by GHGA Member Kübra Narcı! This pipeline is designed to assess and validate the accuracy of variant calling methods in genomic research.

141

Reposted by Cihan Erkut

Wolfgang Huber @wkhuber.bsky.social · 15/02/2025

Heidelberg 2025-02-15

0478

Reposted by Cihan Erkut

Winkler Laboratory @winklerlab.bsky.social · 12/02/2025

#aufstehenfuerdemokratie Um 11:55 Uhr versammelte sich eine große Gruppe von Wissenschaftlern & Unterstützern, um ein Statement für faktenbasierte Entscheidungen und Demokratie abzugeben: Geht wahlen-mit Verstand! Inspirierende Worte von Prof. E. Winkler und Prof. S. Pfister - Danke an Alle!

23513

Reposted by Cihan Erkut

Nadia Davidson @nadia-davidson.bsky.social · 10/02/2025

Our new paper examining how to analyse longread RNA-seq with no reference genome. We compare approaches for assembly and downstream analysis, from transcript accuracy to differential expression. Lead by @alexyfyf.bsky.social. Thnx to all contributors incl. @qgouil.bsky.social for the pea data!

12811

Reposted by Cihan Erkut

Wolfgang Huber @wkhuber.bsky.social · 03/01/2025

How to do differential expression with scRNAseq data? State of the art is "pseudo-bulk" analysis with RNA-seq methods like edgeR or DESeq2, where "cell type" is encoded as discrete categories. Biologically, discrete categories are not always the most appropriate concept.(1/3) doi.org/10.1038/s415...

doi.org

Analysis of multi-condition single-cell data with latent embedding multivariate regression - Nature Genetics

Latent embedding multivariate regression models multi-condition single-cell RNA-seq using a continuous latent space, enabling data integration, per-cell gene expression prediction and clustering-free ...

724793

Reposted by Cihan Erkut

Chise @sailorrooscout.bsky.social · 27/12/2024

HOW COOL IS THIS?! Scientists have discovered a new way to destroy cancer cells. By stimulating aminocyanine molecules with near-infrared light, cancer cells vibrate in sync, enough to break apart their membranes! These “molecular jackhammers” DESTROYED 99% of cancer cells! 🧪🧵⬇️

17663111715

Reposted by Cihan Erkut

Almut Schulze @almutschulze.bsky.social · 20/12/2024

Excited to announce two DFG-funded PhD positions to study Lipid Droplet Heterogeneity in cancer as part of FOR5815. Join us @dkfz-heidelberg if you are interested in #cancermetabolism and #lipidbiology jobs.dkfz.de/en/jobs/1673... jobs.dkfz.de/de/jobs/1673...

jobs.dkfz.de

PhD Student in Lipid Metabolism in Cancer

0127

Reposted by Cihan Erkut

Stefan Fröhling @stefanfrohling.bsky.social · 16/12/2024

Exciting times ahead! The first joint clinical trial of the National Center for Tumor Diseases #OneNCT will address the unresolved question of whether treatment based on multi-layered molecular profiling can improve outcomes in patients with advanced #RareCancers. nct.dkfz.de/en/nct/news/...

nct.dkfz.de

RATIONALE focuses on rare cancers

First multi-site study by the National Center for Tumor Diseases (NCT)

1144

Cihan Erkut @cihanerkut.bsky.social · 13/12/2024

Insider tip: Daniel offers here a very promising project in a very nice workplace. 😉

020

Reposted by Cihan Erkut

Daniel Lipka @dblipka.bsky.social · 08/12/2024

Happy to share our data on the effects of IDH1-mutations on hematopoietic differentiation today at the #ASH24 poster session and now with #HemeSky!

0444

Reposted by Cihan Erkut

Stephen Turner @stephenturner.us · 16/11/2024

Bluesky for Science Starter packs for genomics, bioinformatics, #Rstats, Nextflow. Moderation lists. Feeds. Let's rebuild the old scitwitter community and keep this place nice blog.stephenturner.us/p/bluesky-fo... 🧬🖥️🧪

blog.stephenturner.us

Bluesky for Science

Bluesky starter packs for genomics, bioinformatics, R, and Nextflow

3518268

Reposted by Cihan Erkut

Karla Neugebauer @karlaneugebauer.bsky.social · 27/11/2024

We are happy to share the development of Co-transcriptional Structure Tracking by @leoschaerfen.bsky.social, which measures RNA structure formation during its synthesis in vivo. We are excited to discover the activity of helicases on nascent rRNA! www.biorxiv.org/content/10.1...

biorxiv.org

Rapid folding of nascent RNA regulates eukaryotic RNA biogenesis

An RNA′s catalytic, regulatory, or coding potential depends on RNA structure formation. Because base pairing occurs during transcription, early structural states can govern RNA processing events and d...

47028