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Srishti Patil

@srishtipatil.bsky.social
160 followers 186 following 1 posts

(she/her) PhD student working on colorectal cancer evolution in the theoretical systems biology division @DKFZ, Heidelberg

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Reposted by Srishti Patil
Rob Noble @robjohnnoble.bsky.social · 22/05/2026
Great to have @srishtipatil.bsky.social presenting her new research on early-onset tumours, here at ISEEC 2026. Tomorrow I'll be talking about her previous work with me
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Reposted by Srishti Patil
Chaitanya Gokhale @gokhalecs.bsky.social · 12/03/2026
Fantastic double feature seminar today by @sabinenoebel.bsky.social on tradition, culture and mate copying in #drosophila and a superb theory study of the same by @srishtipatil.bsky.social ! It’s been a pleasure hosting you both here @cctb-wue.bsky.social @uni-wuerzburg.de
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Reposted by Srishti Patil
Chaitanya Gokhale @gokhalecs.bsky.social · 24/02/2026
Thrilled to share our new paper with the brilliant @srishtipatil.bsky.social & @sabinenoebel.bsky.social ! 🎉 Can mate copying maintain phenotypic diversity with multiple male options to choose from? find out @ doi.org/10.1073/pnas... @dkfz.bsky.social @unihalle.bsky.social @cctb-wue.bsky.social
doi.org
PNAS
Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...
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Reposted by Srishti Patil
Genetics Society of America @genetics-gsa.bsky.social · 03/02/2026
In #GENETICS, @srishtipatil.bsky.social, @robjohnnoble.bsky.social, and colleagues present a theoretical framework to determine how to exploit the vulnerability of small tumours to stochastic extinction and the optimal time to switch treatments. buff.ly/HDhvCEN
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Rob Noble @robjohnnoble.bsky.social · 29/11/2025
Now free to read in Genetics (@genetics-gsa.bsky.social): "Preventing evolutionary rescue in cancer using two-strike therapy" #mathonco study by @srishtipatil.bsky.social, @armaanahmed.bsky.social, Yannick Viossat and me, determining the optimal time to switch treatments. doi.org/10.1093/gene...
doi.org
Preventing evolutionary rescue in cancer using two-strike therapy
Abstract. First-line cancer treatment frequently fails due to initially rare therapeutic resistance. An important clinical question is then how to schedule
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Reposted by Srishti Patil
Dan Schrider @samurscicop.bsky.social · 17/01/2025
In the latest from the lab (www.biorxiv.org/content/10.1...), PhD student Amjad Dabi used simulation to investigate the emergence of resistance to therapy in cancer under an evolutionary rescue model. Why does treatment for some cancers fail after a period of initial effectiveness? (1/n)
biorxiv.org
Evolutionary rescue model informs strategies for driving cancer cell populations to extinction
Cancers exhibit a remarkable ability to develop resistance to a range of treatments, often resulting in relapse following first-line therapies and significantly worse outcomes for subsequent treatment...
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